Clinical Trials on Arthropathy of Knee in South Africa

Total 1057 results

Medical University of South Carolina

Completed

Evaluation of the Duration of Bupivacaine Spinal Block in Orthopedic Procedures With and Without Epinephrine Wash

Arthropathy of Knee | Arthropathy of Hip

United States
Duke University
Orthopedic Research and Education Foundation; American Association of Hip and...

Recruiting

Antibiotic Prophylaxis in Patients Undergoing Elective TKA- Multi-center Trial

Arthropathy of Knee | Antibiotic Prophylaxis

United States
Medical University of South Carolina

Completed

Compare Epidural vs. Lumbar Plexus Analgesia After Hip Arthroplasty

Arthropathy of Hip

United States
University of Witwatersrand, South Africa

Completed

Habitual Physical Activity and Sedentary Behavior Following Total Knee Arthroplasty

Knee Osteoarthritis

South Africa
The Hawkins Foundation

Completed

Topical Tranexamic Acid (TXA) in Joint Arthroplasty

Osteoarthritis | Hip Arthropathy | Shoulder Arthropathy

United States
Janssen Research & Development, LLC

Completed

A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JNJ-39439335 in Patients With Osteoarthritis

Osteoarthritis, Knee

South Africa
University of Cape Town

Completed

Study of Hip and Knee Arthroplasty in South Africa

Arthritis, Rheumatoid | Osteoarthritis, Knee | Osteoarthritis, Hip | Arthritis Knee | Arthritis of Hip

South Africa
Aesculap AG
Raylytic GmbH

Recruiting

In-vivo Wear Behaviour of AS Coated Versus Uncoated Columbus® Total Knee Prosthesis (COLRAS)

Knee Osteoarthritis | Osteonecrosis | Knee Arthritis | Instability, Joint | Rheumatoid Arthritis of Knee | Deformity Knee | Primary Osteoarthritis of Knee Nos | Secondary Osteoarthritis of Knee Nos

Australia, Germany
PATH

Completed

Phase I/II Descending Age Study of P2VP8 Subunit Parenteral Rotavirus Vaccine in Healthy Toddlers and Infants

Evaluation of a Rotavirus Vaccine

South Africa
University of Witwatersrand, South Africa

Completed

Analysis of Surgical Mortalities Using the Fishbone Model for Quality Improvement

Complication of Surgical and Medical Care, Unspecified

South Africa
University of Vermont

Completed

Mobile Technology to Support Physical Therapy Exercise (MyTherEx)

Osteoarthritis of Knee | Osteoarthritis Of Hip

United States
Brown University

Completed

Schools Championing Safe South Africa

Prevention or Reduction of HIV Risk Behavior | Prevention or Reduction of Intimate Partner Violence

South Africa
AstraZeneca

Completed

Centralized Pan-South African Survey on the Undertreatment of Hypercholesterolaemia (CEPHEUS)

Undertreatment of Hypercholesterolaemia

South Africa
Cleveland Chiropractic College
Durban University of Technology; Murdoch University

Completed

Comparing Manipulation, Rehabilitation and Combination of the Two in the Treatment of Knee Osteoarthritis

Osteoarthritis, Knee

United States, South Africa
Sefako Makgatho Health Sciences University

Completed

Comparing Quality of Recovery Between Desflurane & Isoflurane in Eye Surgery Patients at Dr George Mukhari Acad Hospital (DIQoR)

Quality of Recovery | Anesthesia Recovery Period

South Africa
Cycle Pharmaceuticals Ltd.
Parexel

Completed

Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride

Acute Intermittent Porphyria | Anti-Psychotic | Management of Manifestations of Psychotic Disorders | Treatment of Schizophrenia | Control Nausea and Vomiting | Relief of Restlessness and Apprehension Before Surgery | Adjunct in the Treatment of Tetanus | Control Manifestations of the Manic Type... and other conditions

South Africa
University of KwaZulu
University of California, San Francisco; Centers for Disease Control and Prevention and other collaborators

Completed

Effectiveness of an HIV-adapted IMCI Training and Supervision Programme for Community Health Workers

Infant Feeding Practices | Prevention of Mother-to-child Transmission of HIV | Antenatal Health Care Utilization | Postnatal Health Care Utilization

South Africa
University of Stellenbosch
National Research Foundation of South Africa

Completed

Joint Position Sense in Individuals With Anterior Knee Pain

Proprioceptive Disorders | Anterior Knee Pain Syndrome

South Africa
Helen Joseph Hospital
University of Johannesburg; Abbott Point of Care; Lodox Systems (Ltd)

Completed

Early Point-Of-Care Blood Tests, ECG & X-rays in the Emergency Department (EPOC-BEX-ED)

Emergency Medicine | Point-of-Care Testing

South Africa
Taiwan Liposome Company

Completed

A Phase 2, Open Label, PK Study of TLC599 in Subject With Osteoarthritis of the Knee

OSTEOARTHRITIS OF THE KNEE

Taiwan, United States
University of Johannesburg

Completed

The Efficacy of Venavine Intensive® on the Quality of Life in Females With Chronic Venous Insufficiency

Venous Insufficiency

South Africa
Smith & Nephew, Inc.

Active, not recruiting

Ten Year Implant Survivorship of the ANTHEM™ PS Total Knee System (ANTHEM PS)

Arthroplasty, Replacement, Knee

Thailand, Korea, Republic of, China, Italy, South Africa
University of Washington
Bill and Melinda Gates Foundation; University of Witwatersrand, South Africa

Not yet recruiting

BIYELA - Bexsero Immunisation in Young Women in Africa

Gonorrhea | Gonorrhea of Pharynx | Gonorrhea of Anus | Gonorrhea of Cervix

South Africa
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Patient Specific Instrumentation in TKR

Osteoarthritis of the Knee

United Kingdom
University of Cape Town
Karolinska Institutet

Completed

Use of Low Sensitivity Pregnancy Test for Self-assessment of Medical Abortion (m-Assist+)

Completion of Medical Abortion

South Africa
Pacira Pharmaceuticals, Inc

Completed

Pharmacokinetic and Pharmacodynamic Study of FX006 in Patients With Osteoarthritis of the Knee

Osteoarthritis of the Knee

Australia
Fin-Ceramica Faenza Spa

Completed

Study for the Treatment of Knee Chondral and Osteochondral Lesions

Knee Chondral Lesion | Knee Osteochondral Lesion

Switzerland, Italy, Austria, Belgium, Germany, Norway, Poland, South Africa, Sweden
GlaxoSmithKline

Completed

Effectiveness Of Single Doses Of Ibuprofen In Patients With Osteoarthritis Of The Knee

Osteoarthritis

Australia
Xgene Pharmaceutical Group
Novotech (Australia) Pty Limited

Completed

A Study of Topical XG004 in Participants With Osteoarthritis of the Knee

Pain

Australia
University of the Western Cape

Completed

Interventions for Patients With a Shortened Dental Arch (SDA-RCT)

Anomaly of Dental Arch

South Africa
DePuy International

Terminated

A Single Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Primary Hip Resurfacing Surgery

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Nonunion of Femoral Fractures

South Africa
AstraZeneca

Completed

A Study of the Efficacy and Safety of MEDI7352 in Subjects With Painful Osteoarthritis of the Knee (BESPOKE)

Painful Osteoarthritis of the Knee

Spain, United Kingdom, South Africa, Poland, Estonia, Denmark, Germany
University of Pretoria

Completed

A Randomized Trial Comparing Oxytocin and Oxytocin + Ergometrine for Prevention of Postpartum Haemorrhage at Caesarean Section

Prevention of Post Partum Haemorrhage

South Africa
Ampio Pharmaceuticals. Inc.

Terminated

Open Label Extension to Assess the Safety of Long-Term Treatment With Ampion for Severe Osteoarthritis (OA) of the Knee

Severe Osteoarthritis of the Knee

United States
University of Pretoria

Not yet recruiting

Kefazolin Versus Kefazolin Plus Metronidazole to Reduce Postpartum Infection

Prevention of Postpartum Sepsis

South Africa
Novartis

Completed

A Quality of Life and Safety Study With Pimecrolimus Cream, 1% in Children (Age 2-12 Years) With Atopic Dermatitis

Atopic Eczema

South Africa
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

Drug-drug Interaction Study With MDV3100 and a Cocktail of Substrates

Castration Resistant Prostate Cancer (CRPC) | Pharmacokinetics of MDV3100

South Africa
Smith & Nephew, Inc.

Completed

Visionaire Health Economics Study Comparing Economic Outcomes Between Visionaire and Standard Instrumentation (VISHE13)

Osteoarthritis, Knee

South Africa
Eastern Virginia Medical School
Gilead Sciences; United States Agency for International Development (USAID); FHI... and other collaborators

Active, not recruiting

Project Engage: Oral PrEP Acceptability

Adherence, Medication | Acceptability of Health Care

South Africa, Zimbabwe
Olatec Therapeutics LLC

Completed

Phase 2 Efficacy Trial of OLT1177 Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee

Osteoarthritis of the Knee

United States
University of Cape Town

Unknown

Self-expandable Metal Stents Versus Multiple Plastic Stents for Palliation of Biliary Obstruction

Biliary Stricture | Cancer of the Pancreas | Bile Duct Obstruction, Extrahepatic | Cancer of the Bile Duct

South Africa
University of Pretoria

Completed

Efficacy of Using a Closing Pack to Reduce Postpartum Sepsis

Prevention of Postpartum Sepsis

South Africa
H. Lee Moffitt Cancer Center and Research Institute
Merck Sharp & Dohme LLC

Completed

Preparedness Study - HPV Vaccine

Sexual Transmission of Infection

United States, South Africa
The Hawkins Foundation

Completed

Sport Cord Test Following ACL Reconstruction

Injury of Anterior Cruciate Ligament

United States
Duke University
The Emmes Company, LLC

Recruiting

Pharmacokinetics of Antiretroviral Drugs in Lactating Women and Breastmilk Fed Infants Under 6 Months of Age in Botswana (BMS02)

HIV Infections | Lactating Women on Select DOI | Breastmilk Fed Infants of Mothers on Select DOI

South Africa
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); Medical Research Council, South Africa

Active, not recruiting

Siyakhana Peer: Evaluating a Peer Recovery Coach Model to Reduce Substance Use Stigma in South African HIV Care

Substance-Related Disorders | HIV | Substance Use | Substance Use Disorders | Treatment Adherence | Treatment Adherence and Compliance | Stigmatization | Delivery of Health Care | Stigma, Social | Attitude of Health Personnel | Community Health Workers | Health Personnel | Health Personnel Attitude | Health Care Seeking... and other conditions

South Africa
Unity Biotechnology, Inc.

Completed

A Study of Single and Repeat Dose Administration of UBX0101 in Patients With Osteoarthritis of the Knee

Knee Osteoarthritis

United States
Ampio Pharmaceuticals. Inc.

Completed

AP-003-C Study to Confirm the Efficacy of Ampion™ in Adults With Pain Due to Severe Osteoarthritis of the Knee

Knee Osteoarthritis | Osteoarthritis, Knee | Knee Arthritis | Knee Pain Chronic

United States
Harriet Shezi Children's Clinic

Unknown

Dosing, Safety and Pharmacokinetic Profile of Rifabutin in Children Receiving Concomitant Treatment With Kaletra (RBT)

Children With Confirmed HIV Infection | Receiving ART Regimen Containing 2 NRTIs + LPV/RTV at Standard Dose | Successfully Completed TB Treatment in the Past 2 to 6 Weeks of Enrollment

South Africa
Regeneron Pharmaceuticals
Teva Pharmaceutical Industries, Ltd.

Completed

Long-Term Safety and Efficacy Study of Fasinumab in Patients With Pain Due to Osteoarthritis (OA) of the Knee or Hip (FACT LTS & OA)

Osteoarthritis of the Knee or Hip

United States, Bulgaria, Chile, Colombia, Denmark, Estonia, Germany, Hong Kong, Hungary, Italy, Lithuania, Mexico, Peru, Poland, Romania, Russian Federation, South Africa, Spain, Sweden, Ukraine, United Kingdom

Clinical Trials on Arthropathy of Knee in South Africa

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