Clinical Trials on Arthrosis in South Africa

Total 712 results

Zimmer Biomet

Completed

A Study to Compare the NexGen LPS and LPS-Flex Knee Implants

Osteoarthritis | Total Knee Arthroplasty

United States, Canada
AbbVie

Active, not recruiting

A Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Participants With Psoriatic Arthritis Who Have an Inadequate Response to at Least One Non-Biologic Disease Modifying Anti-Rheumatic Drug (DMARD) (SELECT - PsA 1)

Psoriatic Arthritis

United States, Argentina, Australia, Belarus, Belgium, Bosnia and Herzegovina, Brazil, Bulgaria, Canada, Chile, China, Colombia, Croatia, Czechia, Estonia, Germany, Greece, Hong Kong, Hungary, Ireland, Israel, Italy, Japan, Korea, Republic... and more
Pfizer

Terminated

Tanezumab and Nerve Function In Arthritis Patients

Osteoarthritis

United States
Hoffmann-La Roche

Completed

An Extension Study of Tocilizumab (Myeloma Receptor Antibody [MRA]) in Patients Completing Treatment in Tocilizumab Core Studies

Rheumatoid Arthritis

France, Germany, Italy, Spain, Sweden, China, United States, Australia, Canada, Mexico, South Africa, United Kingdom, Czech Republic, Finland, Russian Federation, Switzerland, Thailand, Belgium, Denmark, Slovenia, Serbia, Israel, Hong... and more
MiMedx Group, Inc.
Rho, Inc.; NBCD A/S; United BioSource, LLC

Terminated

Phase 2B Micronized DHACM vs. Saline in the Treatment of Knee Osteoarthritis

Knee Osteoarthritis

United States
Hoffmann-La Roche

Completed

A Study to Assess the Effect of Tocilizumab Plus Methotrexate on Safety and Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis

Rheumatoid Arthritis

Colombia, Costa Rica, Mexico, Ecuador, Brazil, Argentina, Chile, Venezuela, Peru, Uruguay
Novartis Pharmaceuticals

Completed

Study to Evaluate the Safety and Efficacy of Secukinumab 300 mg and 150 mg in Adult Patients With Active Psoriatic Arthritis (PsA) After 16 Weeks of Treatment Compared to Placebo

Psoriatic Arthritis

United States, Puerto Rico
Eli Lilly and Company

Completed

A Study in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Germany, United States, Romania, Russian Federation, Argentina, Peru, Poland, Taiwan, Korea, Republic of, India, Chile
Hoffmann-La Roche

Completed

An Extension to Study MA21573, Evaluating Tocilizumab in Patients With Active Rheumatoid Arthritis and an Inadequate Response to Current Non-Biological DMARDs and/or Anti-tumor Necrosis Factor (TNF) Therapy

Rheumatoid Arthritis

Czech Republic, France, Italy, Spain, United Kingdom, Canada, Portugal, Netherlands, Poland, Australia, Saudi Arabia, Romania, Hungary, Greece
Amgen

Completed

Study to Assess if ABP710 is Safe & Effective in Treating Moderate to Severe Rheumatoid Arthritis Compared to Infliximab

Arthritis, Rheumatoid

United States, Spain, Australia, Bulgaria, Germany, Poland, Canada, Czechia, Hungary
Janssen Research & Development, LLC

Terminated

A Dose Range Finding Study of JNJ-38518168 in Patients With Active Rheumatoid Arthritis in Spite of Treatment With Methotrexate

Rheumatoid Arthritis

Poland, Ukraine, Taiwan, United States, Colombia, Mexico, Japan, Korea, Republic of, Russian Federation, Argentina, Chile, Thailand, Hungary, Romania, Czechia, Latvia
Hoffmann-La Roche

Completed

A Study of Tocilizumab in Patients With Active Polyarticular Juvenile Idiopathic Arthritis

Juvenile Idiopathic Arthritis

Belgium, Canada, United States, United Kingdom, Argentina, Germany, Italy, Russian Federation, Spain, Mexico, Poland, Brazil, Australia, France, Peru
Galapagos NV
Gilead Sciences

Completed

Long-term Follow-up Study of GLPG0634 in Active Rheumatoid Arthritis Patients (DARWIN3)

Rheumatoid Arthritis

New Zealand, Belgium, Israel, Chile, Argentina, Colombia, Spain, Australia, Latvia, Poland, Russian Federation, United States, Bulgaria, Czechia, France, Germany, Guatemala, Hungary, Mexico, Moldova, Republic of, Romania, Ukraine
UCB Pharma

Completed

A Placebo Controlled Study to Assess Efficacy and Safety of Certolizumab Pegol in the Treatment of Rheumatoid Arthritis

Rheumatoid Arthritis

United States, Canada, Belgium, Argentina, Israel, Bulgaria, Chile, Russian Federation, Australia, Czechia, Latvia, Ukraine, Croatia
Centocor Ortho Biotech Services, L.L.C.
Schering-Plough

Completed

RESTART C0168Z05 Rheumatoid Arthritis Study

Rheumatoid Arthritis

United States, United Kingdom, Spain, Israel, Finland, Canada, France, Austria, Germany, Netherlands
Hoffmann-La Roche

Completed

A Study of Tocilizumab (RoActemra/Actemra) Versus Adalimumab in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Belgium, Germany, Spain, Sweden, United Kingdom, United States, Brazil, Greece, Portugal, Turkey, Finland, Switzerland, Australia, Mexico, Czech Republic
Hoffmann-La Roche

Terminated

A Study of RoActemra/Actemra (Tocilizumab) Versus Adalimumab in Combination With Methotrexate (MTX) in Patients With Moderate to Severe Active Rheumatoid Arthritis And an Inadequate Response to Treatment With Only One Tumor Necrosis Factor (TNF)-Inhibitor

Rheumatoid Arthritis

Germany, Italy, Spain, United States, France, Sweden, Greece, Russian Federation, Denmark, Finland, Netherlands, Puerto Rico
Janssen Scientific Affairs, LLC

Completed

Comparative and Pragmatic Study of Golimumab Intravenous (IV) (Simponi Aria) Versus Infliximab (Remicade) in Rheumatoid Arthritis (AWARE)

Arthritis, Rheumatoid

United States
Pfizer

Completed

Study Comparing Etanercept in Combination With Methotrexate in Subjects With Rheumatoid Arthritis (PRESERVE)

Arthritis, Rheumatoid

Czech Republic, Colombia, Germany, France, Belgium, Spain, Russian Federation, Poland, Australia, Austria, Chile, Former Serbia and Montenegro, Hungary, Italy, Korea, Republic of, Mexico, Netherlands, Sweden, Taiwan, United Kingdom
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Study Of Celecoxib Or Diclofenac And Omeprazole For Gastrointestinal (GI) Safety In High GI Risk Patients With Arthritis (CONDOR)

Arthritis, Rheumatoid | Osteoarthritis

Canada, Costa Rica, France, Korea, Republic of, Spain, Ukraine, Croatia, Taiwan, China, Serbia, Brazil, Singapore, Belgium, India, Colombia, Netherlands, Russian Federation, United Kingdom, Estonia, Portugal, Sweden, Hong Kong, Latvia, South Africa and more
AbbVie

Completed

A Phase 3 Study to Compare Upadacitinib to Abatacept in Subjects With Rheumatoid Arthritis on Stable Dose of Conventional Synthetic Disease- Modifying Antirheumatic Drugs (csDMARDs) Who Have an Inadequate Response or Intolerance to Biologic DMARDs

Rheumatoid Arthritis (RA)

United States, Argentina, Australia, Belgium, Brazil, Bulgaria, Canada, Czechia, Germany, Greece, Hungary, Ireland, Israel, Italy, Korea, Republic of, Latvia, Mexico, Netherlands, New Zealand, Poland, Portugal, Puerto Rico, Romania, Russian... and more
Pfizer

Completed

A Study To Assess the Immune Response Following Administration Of Influenza and Pneumococcal Vaccines To Subjects With Rheumatoid Arthritis Receiving CP-690,550 Or Placebo

Rheumatoid Arthritis

United States, Poland
Takeda

Terminated

VELVET, a Dose Range Finding Trial of Veltuzumab in Subjects With Moderate to Severe Rheumatoid Arthritis (VELVET)

Rheumatoid Arthritis

United States, Argentina, Canada, Czech Republic, Germany, Hungary, Italy, Mexico, Poland, Spain, United Kingdom
Sandoz
Hexal AG

Completed

Clinical Trial to Compare Treatment With GP2017 and Humira® in Patients With Rheumatoid Arthritis (ADMYRA)

Rheumatoid Arthritis

United States, United Kingdom, Hungary, Italy, Malaysia, Serbia, Mexico, Spain, Czechia, Poland, Germany, Romania, Russian Federation
Nichi-Iko Pharmaceutical Co., Ltd.

Completed

A Phase 3 Study of NI-071 in Participants With Rheumatoid Arthritis (RADIANCE)

Rheumatoid Arthritis

United States, Czechia, Poland, Puerto Rico, Russian Federation, Spain, Ukraine, United Kingdom
Unity Biotechnology, Inc.

Completed

A Study of Single and Repeat Dose Administration of UBX0101 in Patients With Osteoarthritis of the Knee

Knee Osteoarthritis

United States
Pfizer

Completed

Efficacy Study Of Tofacitinib In Pediatric JIA Population

Juvenile Idiopathic Arthritis

United States, Spain, Turkey, Canada, Australia, Israel, United Kingdom, Argentina, Brazil, Poland, Mexico, Belgium, Russian Federation, Ukraine
Novo Nordisk A/S

Terminated

A Trial of NNC0109-0012, an Anti-IL-20 Biologic, in Patients With Active Rheumatoid Arthritis Who Are Inadequate Responders to Methotrexate

Inflammation | Rheumatoid Arthritis

United States, Mexico, Russian Federation, France, Italy, Spain, Argentina, Belgium, Brazil, Czechia, Germany, Poland, Ukraine, Hungary
Hoffmann-La Roche

Terminated

A Study of RO7123520 to Evaluate the Safety and Efficacy in Participants With Moderately To Severely Active Rheumatoid Arthritis (RA) Who Are Inadequately Responding to Anti-Tumor Necrosis Factor (TNF)-Alpha Therapy

Rheumatoid Arthritis

Spain, United Kingdom, United States, Italy, Peru, Argentina, Colombia, Mexico, Germany, Austria, Guatemala
Sandoz

Completed

Comparative Efficacy and Safety Study of GP2015 and Enbrel® in Patients With Rheumatoid Arthritis (EQUIRA)

Rheumatoid Arthritis

Estonia, Italy, Lithuania, United Kingdom, United States, Bulgaria, Czechia, Poland, Slovakia, Spain, Latvia, Serbia, Hungary, Russian Federation, Mexico, Germany
Abbott

Completed

Study Comparing 80 mg of Adalimumab With Placebo, and Demonstrating the Non-inferiority of Monthly 80 mg Adalimumab Dosing Compared With 40 mg Adalimumab Every Other Week Dosing

Rheumatoid Arthritis

United States, Canada, Puerto Rico, Australia, Germany, United Kingdom
UCB Pharma

Completed

A Comparison of Two Assessment Tools in Predicting Treatment Success of Cimzia in Rheumatoid Arthritis Subjects (PREDICT)

Rheumatoid Arthritis

United States
AbbVie

Active, not recruiting

A Study Comparing Risankizumab to Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Have a History of Inadequate Response to or Intolerance to at Least One Disease Modifying Anti-Rheumatic Drug (DMARD) Therapy (KEEPsAKE 1)

Psoriatic Arthritis

United States, Argentina, Australia, Belgium, Bosnia and Herzegovina, Brazil, Bulgaria, Canada, Chile, Croatia, Czechia, Denmark, Estonia, Finland, Germany, Greece, Israel, Italy, Korea, Republic of, Latvia, Lithuania, Malaysia, Mexico and more
Abbott

Completed

Post-marketing Observational Study in Subjects With Rheumatoid Arthritis (ReAlise)

Rheumatoid Arthritis

Australia, Austria, Belgium, France, Germany, Greece, Italy, Netherlands, Portugal, Spain, United Kingdom
Arthrosi Therapeutics

Active, not recruiting

Phase 2 to Assess Efficacy and Safety in AR882 Alone or in Combination With Allopurinol in Patients With Tophaceous Gout

Hyperuricemia | Gout | Arthritis, Gouty | Gout Chronic

United States, New Zealand
Janssen Pharmaceutica N.V., Belgium

Completed

A Study on Assessment of STELARA and Tumor Necrosis Factor Alpha Inhibitor Therapies in Participants With Psoriatic Arthritis (PsaBio)

Psoriatic Arthritis

France, United Kingdom, Belgium, Spain, Netherlands, Greece, Russian Federation
UCB Pharma

Completed

Certolizumab Pegol for the Treatment of Patients With Active Rheumatoid Arthritis (REALISTIC)

Rheumatoid Arthritis

United States, France, Italy, Germany, Spain, Canada, Netherlands
Pfizer

Completed

A Study Comparing 2 Doses Of CP-690,550 Vs. Placebo For The Treatment Of Rheumatoid Arthritis In Patients On Other Background Arthritis Medications

Arthritis, Rheumatoid

United States, Spain, Colombia, Finland, Sweden, Croatia, China, Germany, Australia, Mexico, Poland, Slovakia, Russian Federation, Chile, Denmark, Thailand, United Kingdom, Venezuela, Malaysia, Greece
Janssen Research & Development, LLC
GlaxoSmithKline

Completed

A Study of CNTO 136 (Sirukumab), Administered Subcutaneously, in Patients With Active Rheumatoid Arthritis Despite Disease-Modifying Antirheumatic Drug (DMARD) Therapy (SIRROUND-D)

Arthritis, Rheumatoid

United States, Poland, Ukraine, Taiwan, Mexico, Bulgaria, Malaysia, Romania, Serbia, South Africa, Korea, Republic of, Japan, Canada, Russian Federation, Chile, Lithuania, Colombia, Croatia
Amgen

Completed

Efficacy, Safety, and Tolerability Study of Apremilast to Treat Early Oligoarticular Psoriatic Arthritis. (FOREMOST)

Arthritis, Psoriatic

United States, Spain, Netherlands, Canada, France, Russian Federation, Belgium, Austria, Germany, Italy, United Kingdom
Hoffmann-La Roche

Completed

An Exploratory Study of Tocilizumab in Patients With Active Rheumatoid Arthritis (RA) and an Inadequate Response to Current Non-Biologic DMARDs and/or Anti-TNF Therapy.

Rheumatoid Arthritis

Belgium, Czech Republic, France, Italy, Spain, Sweden, United Kingdom, Canada, Greece, Ireland, Portugal, Turkey, Netherlands, Denmark, Finland, Germany, Luxembourg, Austria, Switzerland, Poland, Australia, Hungary, Saudi Arabia, Romania and more
Axsome Therapeutics, Inc.

Unknown

A Study to Assess the Efficacy and Safety of AXS-02 in Subjects With Knee OA Associated With Bone Marrow Lesions (COAST-1)

Osteoarthritis, Knee

United States, Australia
Janssen Research & Development, LLC
GlaxoSmithKline

Completed

Long-term Safety and Efficacy of Sirukumab in Participants With RA Completing Studies CNTO136ARA3002 or CNTO136ARA3003 (SIRROUND-LTE)

Arthritis, Rheumatoid

United States, Poland, Ukraine, United Kingdom, Germany, Taiwan, Mexico, Portugal, Spain, Bulgaria, Malaysia, Romania, Serbia, South Africa, Korea, Republic of, Japan, Canada, Russian Federation, Chile, Puerto Rico, Austria, Argen... and more
Pfizer

Terminated

A Study Of The Safety And Efficacy Of PF-04191834 In Patients With Osteoarthritis Of The Knee

Osteoarthritis, Knee

United States, Sweden, Canada
Gilead Sciences
Galapagos NV

Completed

Filgotinib Versus Placebo in Adults With Active Rheumatoid Arthritis (RA) Who Have an Inadequate Response to Biologic Disease-modifying Anti-rheumatic Drug(s) (DMARDs) Treatment (FINCH 2)

Rheumatoid Arthritis

United States, France, Germany, Spain, Israel, Japan, Korea, Republic of, Belgium, Argentina, Poland, Hungary, United Kingdom, Mexico, Australia, Switzerland
Hoffmann-La Roche
Genentech, Inc.

Completed

Extension Study to Assess the Efficacy and Safety of Repeat Treatment With Rituximab (MabThera) in Participants With Active Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

Belgium, Germany, Poland, Spain, United States, Canada, Mexico, New Zealand, United Kingdom, Finland, Israel, Italy, Sweden, Australia, Brazil, Czech Republic
Noven Pharmaceuticals, Inc.

Completed

A 12-week Study to Evaluate the Efficacy and Safety of HP-5000 in Subjects With Osteoarthritis Pain of the Knee

Osteoarthritis Pain of the Knee

United States
Cubist Pharmaceuticals LLC
Pfizer

Completed

Efficacy and Safety Study Evaluating ADL5859 and ADL5747 in Participants With Pain Due to Osteoarthritis of the Knee

Osteoarthritis of the Knee

United States
Avanos Medical

Completed

Cooled Radiofrequency vs. Hyaluronic Acid to Manage Knee Pain

Osteoarthritis of the Knee

United States
Kolon TissueGene, Inc.

Recruiting

A Study to Determine the Safety and Efficacy of TG-C in Subjects With Kellgren and Lawrence Grade 2 or 3 OA of the Knee

Degenerative Osteoarthritis

United States

Clinical Trials on Arthrosis in South Africa

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