Clinical Trials on Atherogenic Dyslipidemia

Total 2820 results

Pfizer

Terminated

Carotid B-mode Ultrasound Study to Compare Anti-Atherosclerotic Effect of Torcetrapib/Atorvastatin to Atorvastatin. (RADIANCE 2)

Mixed Hyperlipidemia

United States, Canada, Czech Republic, Finland, France, Netherlands
AstraZeneca

Completed

12-week Open-label, Phase IIIb Comparing Efficacy and Safety of Rosuvastatin (CRESTOR™) in Combination With Ezetimibe (GRAVITY)

Atherosclerosis | Hypercholesterolemia | Coronary Heart Disease

Chile, Argentina, Brazil, United States, Colombia, Lithuania, Netherlands, Peru, Venezuela
University of Turku
University of Eastern Finland

Active, not recruiting

OAT-GUT-BRAIN: Effects of Oats and Rice on Comprehensive Health of Metabolically Challenged Individuals

Overweight and Obesity | High Blood Pressure | High Cholesterol/Hyperlipidemia

Finland
LIB Therapeutics LLC
Medpace, Inc.

Active, not recruiting

Study of Long-Term Efficacy and Safety of LIB003 in CVD or High Risk for CVD Patients Needing Further LDL-C Reduction (LIBerate-HR)

Cardiovascular Diseases | Hypercholesterolemia | Cardiovascular Risk Factor | Cardiovascular Stroke

United States, Israel, India
Mayo Clinic

Completed

Renal Hemodynamic Effects of the HMG-CoA Reductase Inhibitors in Normal Volunteers and in Patients With Chronic Renal Failure

Hypertension | Hyperlipidemia | Chronic Renal Failure
Organon and Co

Completed

A Long-term Safety and Tolerability Study of Ezetimibe Plus Atorvastatin in Participants With Coronary Heart Disease, Multiple Risk Factors, or Hypercholesterolemia Not Controlled by Atorvastatin (P01418/MK-0653-032)

Hypercholesterolemia
Organon and Co

Completed

Effectiveness and Safety of Ezetimibe Added to Atorvastatin in Patients With High Cholesterol and Coronary Heart Disease (Study P03740)

Hypercholesterolemia | Coronary Heart Disease
Organon and Co
Merck Sharp & Dohme LLC

Completed

Comparison of Co-administration of Ezetimibe Plus Simvastatin Versus Simvastatin Alone in Primary Hypercholesterolemia (P03476)

Atherosclerosis | Hypercholesterolemia | Coronary Heart Disease
Organon and Co

Completed

Investigational Drug Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-801)

Coronary Disease | Hypercholesterolemia
Organon and Co

Completed

Co-administration Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-802)(COMPLETED)

Coronary Disease | Hypercholesterolemia
Organon and Co

Completed

An Investigational Drug Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-804)(COMPLETED)

Coronary Disease | Hypercholesterolemia
Shenzhen People's Hospital
Innovent Biopharmaceutical Co., Ltd.

Active, not recruiting

Application of PCSK9 Inhibitors in Patients With Heterozygous Familial Hypercholesterolemia

Efficacy and Safety | Heterozygous Familial Hypercholesterolemia | PCSK9

China
Assiut University

Active, not recruiting

Familial Hypercolerstremia as Risk Factor in Stemi Patient Who Underwent Ppci

Familial Hypercholesterolemia

Egypt
First Affiliated Hospital of Harbin Medical University

Unknown

Lipid-lowering Effects of Gefarnate in Statin-treated Coronary Heart Disease Patients With Residual Hypertriglyceridemia

Coronary Artery Disease

China
Sun Yat-sen University

Unknown

The Healthy Cantonese Diet on Cardiometabolic Syndrome

Hyperglycemia | Cardiovascular Diseases | Hypertension | Hyperlipidemias | Cardiovascular Risk Factor | High Blood Pressure
Albert Einstein College of Medicine
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Controlling Hypertension in Diabetes- Feasibility Study (COACH-D)

Hypertension | Type 2 Diabetes | Hyperlipidemia

United States
St. Louis University

Completed

Digital Ankle Brachial Index (ABI) as a Screening Tool in Detecting Peripheral Arterial Disease

Smoking | Hypertension | Diabetes | Amputation | Hypercholesterolemia | Peripheral Artery Disease

United States
Merck Sharp & Dohme LLC

Completed

Lipid Efficacy and Safety in Participants With Mixed Hyperlipidemia (MK-0524B-024)

Mixed Hyperlipidemia
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Safety and Efficacy of Mipomersen (ISIS 301012) As Add-on Therapy in High Risk Hypercholesterolemic Patients

Hypercholesterolemia | Coronary Heart Disease

United States
Laval University

Completed

Effects of LDL Apheresis System on the Expression of Genes Involved in Lipoprotein Metabolism and Inflammation in Homozygotes for Familial Hypercholesterolemia (LA-PBMC)

Familial Hypercholesterolemia

Canada
Nordic Pharma, USA
Nutrasource Pharmaceutical and Nutraceutical Services, Inc.

Withdrawn

Efficacy Study of Daily Pro-Omega LDL for Low-Density Lipoprotein Cholesterol and Triglyceride Reduction (PrOteCT)

Mixed Hyperlipoproteinemia
Daping Hospital and the Research Institute of Surgery...
AstraZeneca

Unknown

Effect of Rosuvastatin Therapy on HDL2 Level

Coronary Heart Disease | Hyperlipemia

China
Washington University School of Medicine
Pennington Biomedical Research Center

Completed

Addition of Phytosterols to a Low Phytosterol Diet (phyteaux-I)

Hypercholesterolemia | Coronary Heart Disease

United States
Amsterdam Molecular Therapeutics
The Clinical Trial Company

Unknown

Study to Re-assess and Re-confirm Data Previously Recorded About the Incidence and Severity of Acute Abdominal "Pancreatitis" Episodes in Lipoprotein Lipase Deficient (LPLD) Subjects Previously Enrolled on AMT Clinical Studies

Lipoprotein Lipase Deficiency

Canada
Positive Trial Group

Terminated

Primary Prevention of Major Adverse Cardiac Events (MACE) With Standard and Intensive Statin Treatment in Patients With Diabetes: Survival and Cardiovascular Event Assessments (POSITIVE)

Hypertension | Type 2 Diabetes | Hypercholesterolemia

Japan
AstraZeneca

Completed

Polaris - Crestor 40 mg vs Atorvastatin 80 mg for 26 Weeks (POLARIS)

Hypercholesterolemia | Coronary Heart Disease
Medical University of Vienna

Completed

Correlation of Flicker Induced and Flow Mediated Vasodilatation in Patients With Endothelial Dysfunction and Healthy Volunteers.

Hypertension | Diabetes Mellitus, Type 1 | Hypercholesterolemia | Regional Blood Flow

Austria
AstraZeneca

Completed

Evaluation of the Efficacy of Rosuvastatin in Daily Practice (TARGET)

Hypercholesterolemia | Coronary Heart Disease
Drexel University
Mercy Health

Not yet recruiting

Effects of Remote-based Resistance Training on Cardiometabolic Risk Factors, Cognitive Function, and Quality of Life in Adults Living With Alzheimer's Disease and/or Related Dementias

Quality of Life | Hypertension | Obesity | Body Weight | Cognitive Impairment | Dyslipidemias | Dementia | Alzheimer Disease | Blood Pressure | Aging | Mild Cognitive Impairment | Lewy Body Disease | Frontotemporal Dementia | Dementia, Vascular | Obesity, Abdominal | Blood Glucose, High | Blood Glucose, Low
Guangdong Provincial Hospital of Traditional Chinese...

Recruiting

Study on Hyperlipidemia Combined With Carotid Atherosclerosis With ShenJu Granules

Carotid Atherosclerosis | Hyperlipidemia

China
Novartis Pharmaceuticals

Recruiting

Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Adolescent ORION-16 or ORION-13 Studies (V-PEDS-OLE)

Heterozygous or Homozygous Familial Hypercholesterolemia

Netherlands, Israel, Hungary, Italy, Germany, Spain, United States, France, Norway, Russian Federation, South Africa, Turkey, United Kingdom, Canada, Switzerland, Brazil, Lebanon, Slovenia, Poland, Taiwan, Malaysia
Cairo University

Recruiting

Combined Effect of Acitretin and Narrow Band Ultraviolet B on Vitiligo Repigmentation

Depression | Liver Diseases | Hyperlipidemias | Xerosis

Egypt
Amgen

Completed

Safety and Tolerability of Repatha® (Evolocumab) in Indian Participants With Homozygous Familial Hypercholesterolemia (RAMAN)

Homozygous Familial Hypercholesterolemia HoFH

India
Wake Forest University

Active, not recruiting

The Medication Experience Study

Depression | Hypertension | Diabetes | Elevated Cholesterol

United States
Organon and Co
Schering-Plough

Completed

The Effects of Ezetimibe/Simvastatin 10/20 mg Versus Simvastatin 40 mg in High Cholesterol and Coronary Heart Disease Study (P04039AM2)(COMPLETED)

Coronary Disease | Hypercholesterolemia
Arrowhead Pharmaceuticals

Active, not recruiting

Study of ARO-APOC3 (Plozasiran) in Adults With Familial Chylomicronemia Syndrome (FCS) (PALISADE)

Familial Chylomicronemia

Korea, Republic of, Canada, Australia, Singapore, Belgium, Spain, Japan, United States, Austria, Germany, Ireland, Oman, Poland, Israel, New Zealand, Argentina, France, Croatia, Mexico, Serbia, Turkey
Geisinger Clinic

Completed

Evaluating the Efficacy of Pediatric Lipid Screening Alerts

Hypercholesterolemia | Hypercholesterolemia, Familial | Hypercholesteremia in Children | Hyperlipidemia in Children

United States
Ohio State University

Completed

Creating Healthier Communities Through Meaningful Partnerships: A Model From the National African American Male Wellness Initiative - OSU Partnership

Hypertension | Diabetes | Weight Loss | Smoking Reduction | Sedentary Behavior | Diet, Healthy | High Cholesterol

United States
Organon and Co
Merck Sharp & Dohme LLC

Completed

Ezetimibe Plus Atorvastatin Versus Atorvastatin in Untreated Subjects With Primary Hypercholesterolemia and Coronary Heart Disease (P03396)

Coronary Artery Disease | Atherosclerosis | Hypercholesterolemia
Organon and Co
Merck Sharp & Dohme LLC

Terminated

Switching to Rosuvastatin Versus Adding Ezetimibe to Atorvastatin Versus Doubling the Dose of Atorvastatin in Patients With Hypercholesterolemia and Risk Factors (P03708)

Coronary Artery Disease | Atherosclerosis | Hypercholesterolemia
Organon and Co

Completed

Co-administration Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-803)

Coronary Disease | Hypercholesterolemia
University of Primorska

Completed

Clinical Trials of Two Helichrysum Infusions in Adults (SMILJ)

Hyperglycemia | Inflammation | Hypertension | Hypercholesterolemia | Hyperlipidemias | Microbial Colonization | Overweight and Obesity

Slovenia
Akcea Therapeutics
CaligorRx, Inc.

No longer available

Volanesorsen Early Access Program for Patients With Familial Chylomicronemia Syndrome (FCS)

Familial Chylomicronemia
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Atorvastatin Effectiveness and Safety in Cardiology Patients in Real World Setting (ATTENTION)

Coronary Artery Disease, Hypercholesterolemia, Hypertension

China
Seoul National University Hospital
Korea Otsuka Pharmaceutical Co., Ltd.

Completed

Effect of Probucol and/or Cilostazol on Mean IMT in Patients With Coronary Heart dIsease (IMPACTonIMT)

Hyperlipidemias

Korea, Republic of
Barbara Jakše s.p.

Completed

Low Fat Plant-Based Supplemented Diet Effects on Risk Factors for Chronic Non-communicable Diseases (LFPBDS2)

Hyperlipidemia | Metabolic Syndrome X
University of Texas Southwestern Medical Center

Withdrawn

Cross-over Pilot Study of Blood Cholesterol Response to Dietary Saturated Fat in Patients With Autosomal Dominant Hypercholesterolemia

Familial Hypercholesterolemia

United States
Unilever R&D
Commonwealth Scientific and Industrial Research Organisation, Australia

Completed

The Effect of Plant Sterols on the Blood Lipid Profile of Subjects With and at High Risk of Type 2 Diabetes Mellitus

Vascular Diseases | Diabetes Mellitus | Hypercholesterolemia

Australia
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Safety and Efficacy of Mipomersen in Patients With Severe Hypercholesterolemia on a Maximally Tolerated Lipid-Lowering Regimen and Who Are Not on Apheresis

Hypercholesterolemia | Coronary Heart Disease

South Africa, Germany, United States, United Kingdom, Canada, Czech Republic
Sang Hak Lee

Unknown

Comparison of the Efficacy and Safety of AtorVastatin mOnotherapy vs. Combination Atorvastatin/Fenofibric Acid (AVOCADO)

Mixed Hyperlipidemia

Korea, Republic of

Clinical Trials on Atherogenic Dyslipidemia

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