Clinical Trials on B-Thalassemia

Total 6386 results

Federico II University

Completed

The Role of OCTA in Patients Affected by Beta Thalassemia

Thalassemia

Italy
HaEmek Medical Center, Israel

Completed

Endocrine and Nutritional Assessment in B Thalassemia Major

Thalassemia

Israel
Cerus Corporation

Completed

Study to Evaluate Efficacy and Safety of S303 Treated Red Blood Cells (RBCs)in Subjects With Thalassemia Major Requiring Chronic RBC Transfusion

Thalassemia Major

Turkey, Italy
HemaQuest Pharmaceuticals Inc.

Completed

Phase 1/2 Study of HQK-1001 in Patients With Beta Thalassemia

Beta Thalassemia

Lebanon, Thailand
Tanta University

Completed

Effect of Spirulina Compared to Amlodipine on Cardiac Iron Overload in Children With Beta Thalassemia

Beta Thalassemia Major

Egypt
Bioray Laboratories
Xiangya Hospital of Central South University; The 923rd Hospital of Joint Logistics...

Recruiting

Long-term Follow-up Study of BHC001 for TDT

Thalassemia, Beta

China
Shanghai BDgene Co., Ltd.
920th Hospital of Joint Logistics Support Force of People's Liberation Army...

Recruiting

A Study Evaluating the Safety and Efficacy of the BD211 Drug Product in β-Thalassemia Major Participants

Hematologic Diseases

China
Nanfang Hospital of Southern Medical University
Shenzhen Second People's Hospital; Shenzhen Children's Hospital; ZhuHai Hospital and other collaborators

Recruiting

Association of Hb F Level With Clinical Severity of Beta Thalassemia

Beta Thalassemia

China
Nanfang Hospital of Southern Medical University
303rd Hospital of the People's Liberation Army; Liuzhou Municipal Maternity... and other collaborators

Recruiting

Genetic Variants Affecting the Clinical Severity of Beta Thalassemia

Beta Thalassemia

China
National Taiwan University Hospital

Recruiting

Observing the Changes of Endocrine and Metabolism in Patients With Thalassemia Major

Thalassemia Major

Taiwan
National Institute of Allergy and Infectious Diseases...

Recruiting

Screening for Alpha Thalassemia in Healthy Volunteers

Alpha Thalassemia

United States
DisperSol Technologies, LLC

Completed

Pilot Study to Assess the Safety, PK and Iron Chelating Activity of DST-0509 (Deferasirox) in Thalassemia Patients Refractory to Chelation

Thalassemia Major

Thailand, United States
Assiut University

Completed

Evaluation of Nutritional Status in Thalassemia Major Patients in Assiut Children Hospital

Thalassemia Major

Egypt
National Human Genome Research Institute (NHGRI)

Completed

Perceptions of Thalassemia Major in Singapore: An Exploratory Study of Stigma

Thalassemia Major

Singapore
HaEmek Medical Center, Israel

Completed

Demographic, Clinical, Laboratory and Genetical Characteristics of Patients With Beta Thalassemia Intermedia

Thalassemia

Israel
Deborah Rund

Completed

Genetic Factors Affecting the Severity of Beta Thalassemia

Beta Thalassemia

Israel
Deborah Rund

Completed

Genetics of Alpha Thalassemia in Israeli Ethnic Groups

Alpha Thalassemia

Israel
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of INC424 in Regularly Transfused Patients With Thalassemia.

Thalassemia Major

Thailand, Turkey, Italy, Lebanon, Greece
First Affiliated Hospital of Guangxi Medical University

Unknown

Haploidentical Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major

Thalassemia Major

China
Nanfang Hospital of Southern Medical University

Unknown

Unrelated Umbilical Cord Blood Following HLA-haploidentical Hematopoietic Stem Cell Transplantation in Patients With β-thalassemia Major

Thalassemia Major

China
Ann & Robert H Lurie Children's Hospital of Chicago

Unknown

Long Term Outcomes in β Thalassemia Major

Thalassemia Major

United States
HealthCore-NERI
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Evaluating the Safety and Effectiveness of Decitabine in People With Thalassemia Intermedia

Thalassemia

United States, Canada
Mahidol University

Completed

The Change of Coagulation Markers in Children With β-thalassemia Disease After Stem Cell Transplantation

Thalassemia

Thailand
Ain Shams University

Unknown

Therapeutic Effect and Safety of Combined Hydroxyurea With Recombinant Human Erythropoietin.

Thalassemia Intermedia

Egypt
Mahidol University
ChaingMai University

Completed

Effect of Antioxidant Cocktail in Beta-thalassemia/Hb E Patients

Thalassemia

Thailand
Dana-Farber Cancer Institute
Tehran University of Medical Sciences

Completed

Monitoring of Erythroid Lineage Specific Chimerism Following Allogeneic Hematopoietic Transplantation for Thalassemia Major

Thalassemia Major

United States, Iran, Islamic Republic of
Weill Medical College of Cornell University

Unknown

The Effect of Vitamin D Supplementation on Calcium Excretion in Thalassemia: a Dose Response Study

Thalassemia Major

United States
National Institute of Diabetes and Digestive and...

Completed

5-Azacytidine and Phenylbutyrate to Treat Severe Thalassemia

Beta Thalassemia

United States
Shire

Terminated

Safety, Efficacy and Pharmacokinetics of an Oral Iron Chelator Given for a Year to Pediatric Patients With Iron Overload

Beta-Thalassemia | Transfusional Iron Overload

United States, Lebanon, Canada, Italy, Turkey
Ente Ospedaliero Ospedali Galliera
University of Campania "Luigi Vanvitelli"; Reggio Calabria; Ospedale Maggiore... and other collaborators

Completed

Efficacy and Safety of Neridronate (Nerixia®)to Treat Osteoporosis in Patients With TM and TI (Nerixia)

Osteoporosis | Thalassemia Major | Thalassemia Intermedia

Italy
First Affiliated Hospital of Guangxi Medical University
Peking University People's Hospital; Ruijin Hospital; The Affiliated Hospital... and other collaborators

Recruiting

Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major: A Multicenter, Prospective Clinical Study

Thalassemia Major

China
Bioray Laboratories
First Affiliated Hospital of Guangxi Medical University

Suspended

Safety and Efficacy Evaluation of γ-globin Reactivated Autologous Hematopoietic Stem Cells

Thalassemia Major

China
Children's Hospital Karachi

Completed

Clinical Experience of Thalidomide in Thalassemic Patients

Thalassemia, Beta

Pakistan
Allife Medical Science and Technology Co., Ltd.

Unknown

iHSCs With the Gene Correction of HBB Intervent Subjests With β-thalassemia Mutations

Thalassemia
Tanta University

Completed

Effects of Spirulina on Cardiac Functions in Children With Beta Thalassemia Major

Beta Thalassemia

Egypt
Case Western Reserve University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Chelation Therapy of Iron Overload With Pyridoxal Isonicotinoyl Hydrazone

Hematologic Diseases | Iron Overload | Hemoglobinopathies | Thalassemia | Beta-Thalassemia | Anemia (Iron-Loading)
Shire

Completed

Safety and Pharmacodynamic Study of an Oral Iron Chelator Given for 6 Months to Patients With Iron Overload

Beta-thalassemia | Transfusional Iron Overload

United States, United Kingdom, Italy, Thailand, Turkey
Kevin H.M. Kuo, MD, MSc, FRCPC

Unknown

Amlodipine as Adjuvant Treatment to Iron Chelation for Prevention of Cardiac Iron Overload in Thalassemia Patients (CANALI)

Iron Overload | Beta-Thalassemia

Canada
FerroKin BioSciences, Inc.

Completed

Safety and Pharmacokinetic Study of Escalating Multiple Doses of an Iron Chelator in Patients With Iron Overload

Beta-thalassemia | Transfusional Iron Overload

United States, Australia, Thailand
Novartis Pharmaceuticals

Completed

An Extension Study of Iron Chelation Therapy With Deferasirox (ICL670) in β-thalassemia Patients With Transfusional Iron Overload

Transfusional Iron Overload in β-thalassemia

United States, Greece, Argentina, Germany, Belgium, Italy, United Kingdom, France, Tunisia, Canada, Turkey, Brazil
Hillel Yaffe Medical Center

Unknown

Prevalence Of Microalbuminuria Among Children Suffering From Sickle Cell Nephropathy and Sickle Cell/Beta-Thalassemia

Sickle Cell Anemia | Beta-Thalassemia | Microalbuminuria
Ain Shams University

Completed

The Use of CGMS to Detect Alterations of Blood Glucose in Thalassemic Patients

Diabetes | Prediabetes | B-Thalassemia
Novartis Pharmaceuticals

Completed

Phase I Study to Examine the Effect of Deferasirox on Renal Hemodynamics in β-thalassemia Patients With Transfusional Iron Overload

Transfusional Iron Overload | β-thalassemia

Italy
National Institute of Diabetes and Digestive and...

Completed

Hydroxyurea to Treat Beta-Thalassemia (Cooley's Anemia)

Beta Thalassemia | Hemoglobinopathy

United States
Children's Hospital of Philadelphia
Ann & Robert H Lurie Children's Hospital of Chicago; The Cooley's Anemia Foundation...

Completed

Combination Deferasirox and Deferiprone for Severe Iron Overload in Thalassemia

Thalassemia Major With Severe Transfusional Iron Overload

United States
Shiraz University of Medical Sciences

Completed

Immunomodulatory Effects of Silymarin in Patients With Beta-Thalassemia Major

Immune Abnormalities

Iran, Islamic Republic of
Affiliated hospital of guangxi medical university...
Zhongshan Hospital Xiamen University; The Affiliated Nanjing Drum Tower Hospital... and other collaborators

Unknown

Efficacy of Basiliximab in the Prevention of Acute Graft-versus-host Disease in Unrelated Allogeneic Hematopoietic Stem Cell Transplantation Therapy for Thalassemia Major

Beta-Thalassemia Major

China
Fakultas Kedokteran Universitas Indonesia

Completed

Zinc Supplementation on Cellular Immunity in Thalassemia Major

Thalassemia | Immunosuppression | Splenectomy; Status

Indonesia
Novartis Pharmaceuticals

Terminated

Safety and Efficacy of Deferasirox in Combination With Desferoxamine in β-thalassaemia Patients With Severe Cardiac Iron Overload

Cardiac Iron Overload | Transfusion-dependent β-thalassemia Patients

Greece
Emory University
Patient-Centered Outcomes Research Institute

Completed

Decision Aid for Therapeutic Options In Sickle Cell Disease

Sickle Cell Disease | Sickle Cell Anemia | Hemoglobin SC | Hemoglobin SS | Hemoglobin Beta Thalassemia

United States

Clinical Trials on B-Thalassemia

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