Clinical Trials on BCLC Stage C Adult Hepatocellular Carcinoma

Total 322 results

National Cancer Institute (NCI)

Completed

Lapatinib in Treating Patients With Locally Advanced or Metastatic Biliary Tract or Liver Cancer That Cannot Be Removed By Surgery

Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Recurrent Extrahepatic Bile Duct Cancer | Recurrent Gallbladder Cancer | Unresectable Extrahepatic Bile Duct Cancer | Unresectable Gallbladder Cancer | Adult Primary Hepatocellular...

United States
National Cancer Institute (NCI)

Completed

Lapatinib Ditosylate in Treating Patients With Unresectable Liver or Biliary Tract Cancer

Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Recurrent Extrahepatic Bile Duct Cancer | Recurrent Gallbladder Cancer | Unresectable Extrahepatic Bile Duct Cancer | Unresectable Gallbladder Cancer | Adult Primary Hepatocellular...

United States
National Cancer Institute (NCI)

Completed

Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer

Radiation Toxicity | Malignant Neoplasm | Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Ependymoma | Adult Mixed Glioma | Adult Oligodendroglioma | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the... and other conditions

United States
National Cancer Institute (NCI)

Completed

Erlotinib in Treating Patients With Unresectable Liver, Bile Duct, or Gallbladder Cancer

Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Recurrent Extrahepatic Bile Duct Cancer | Recurrent Gallbladder Cancer | Unresectable Extrahepatic Bile Duct Cancer | Unresectable Gallbladder Cancer | Adult Primary Hepatocellular... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Yttrium Y-90 Radioembolization in Treating Patients With Metastatic Liver Cancer

Stage IV Liver Cancer | Stage IVA Liver Cancer | Stage IVB Liver Cancer | Metastatic Liver Carcinoma

United States
Ain Shams University

Unknown

Recurrence Rate of Hepatocellular Carcinoma After Treatment of Chronic Hepatits C Patients With Direct Acting Antivirals: Randomized Controlled Phase 3 Trial (CAUTIOUS)

Hepatocellular Carcinoma | Hepatitis C, Chronic

Egypt
Assistance Publique - Hôpitaux de Paris
ANRS, Emerging Infectious Diseases

Terminated

Primary Prevention Hepatocellular Carcinoma by Metformin (METFOVIR)

Hepatocellular Carcinoma | Hepatitis C, Chronic | Cirrhosis

France
National Cancer Institute, Milan
Associazione Italiana per la Ricerca sul Cancro

Completed

Treatment With IFN After Curative Resection of HCC in HCV-Related Cirrhosis

Liver Cirrhosis | Hepatocellular Carcinoma | Hepatitis C Virus Infection | Hepatic Resection | Interferon Treatment

Italy
Panolos Bioscience

Recruiting

Phase I Study to Evaluate Safety and Anti-tumor Activity of PB101, an Anti-angiogenic Immunomodulating Agent

Metastatic Colorectal Cancer | Hepatocellular Carcinoma | Gastric Cancer | Solid Tumor | Advanced Solid Tumor | Solid Tumor, Adult

Korea, Republic of
M.D. Anderson Cancer Center

Recruiting

Enhanced Outpatient Symptom Management to Reduce Acute Care Visits Due to Chemotherapy-Related Adverse Events

Metastatic Pancreatic Carcinoma | Stage IV Pancreatic Cancer AJCC v8 | Clinical Stage IV Gastric Cancer AJCC v8 | Stage IV Colon Cancer AJCC v8 | Stage IV Rectal Cancer AJCC v8 | Stage IVA Colon Cancer AJCC v8 | Stage IVA Rectal Cancer AJCC v8 | Stage IVB Colon Cancer AJCC v8 | Stage IVB Rectal Cancer... and other conditions

United States
Mayo Clinic

Recruiting

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors (PNeoVCA)

Metastatic Renal Cell Carcinoma | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage IIIA Breast Cancer AJCC v8 and other conditions

United States
Albert Einstein College of Medicine
National Cancer Institute (NCI)

Withdrawn

Isolated Limb Perfusion With Melphalan in Treating Patients With Stage IIIB-IV Melanoma or Sarcoma

Recurrent Melanoma | Stage IV Melanoma | Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Squamous Cell Carcinoma of the Skin | Recurrent Skin Cancer | Stage IIIB Melanoma | Stage IIIC Melanoma | Basal Cell Carcinoma of the Skin | Eccrine Carcinoma...

United States
Carilion Clinic
Sanofi

Terminated

A Phase II Evaluation of Docetaxel and Carboplatin Followed by Tumor Volume Directed Pelvic Irradiation

Advanced Endometrial Adenocarcinoma, Stage III A, B, C

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Mycophenolate Mofetil and Cyclosporine in Reducing Graft-Versus-Host Disease in Patients With Hematologic Malignancies or Metastatic Kidney Cancer Undergoing Donor Stem Cell Transplant

Clear Cell Renal Cell Carcinoma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent... and other conditions

United States, Germany, Italy
Royal North Shore Hospital

Active, not recruiting

Liver Function Investigation With SPECT (LiverINSPECT)

Liver Cancer, Adult

Australia
Stanford University
National Cancer Institute (NCI)

Recruiting

Development of 3DMPUS as a Decision Support Tool for Patients With Liver Tumors Undergoing Therapy (3DMPUS)

Liver Cancer, Adult

United States
Centre Hospitalier Universitaire de Saint Etienne

Terminated

Analgesia by Transversus Abdominis Plane Nerve Block in Patients Undergoing Liver Resection. (BLOC-TAP)

Liver Cancer, Adult

France
University Hospital Inselspital, Berne

Completed

Accuracy Assessment for Computer-assisted Surgical Interventions of the Liver (CALS)

Adult Liver Cancer

Switzerland
MTI University

Unknown

Study of the Early Occurrence of Hepatocellular Carcinoma (HCC) in Egyptian HCV Infected Patients Receiving Sofosbuvir and Daclatasvir

Hepatitis C

Egypt
Benha University

Completed

Plasma MicroRNA for Prediction of Hepatocellular Carcinoma

Hepatitis C

Egypt
Target PharmaSolutions, Inc.

Completed

Direct Acting Antiviral-Post Authorization Safety Study

Hepatocellular Carcinoma | Hepatitis C

United States, Spain, Germany, France, Italy
Egyptian Liver Hospital

Active, not recruiting

The Study of the Validation of General Evaluation Score (GES) in the Prediction of Hepatocellular Carcinoma Risk Among Patients With Advanced Fibrosis and Cirrhosis Who Achieved Sustained Virological Response for Hepatitis C Virus After Direct Acting Antiviral Drugs

Hepatocellular Carcinoma

Egypt
Arbor Research Collaborative for Health
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Adult-to-Adult Living Donor Transplant Cohort Study (A2ALL-2)

End Stage Liver Disease | Liver Diseases | Liver Cirrhosis | Hepatitis C | Hepatocellular Cancer

United States, Canada
Johns Hopkins University
King Faisal Specialist Hospital and Research Center in Riyadh (Saudi Arabia) and other collaborators

Recruiting

International Study of High-Risk Patients for Hepatocellular Carcinoma Using Liquid Biopsy (STOP-HCC)

Liver Cirrhosis | Hepatocellular Carcinoma | Liver Cancer | Early Stage Liver Cancer

Saudi Arabia, Vietnam
Rigshospitalet, Denmark

Completed

Ablation of Hepatocellular Carcinoma: a Nationwide Study

Hepatocellular Carcinoma | Hepatitis C | Ablation

Denmark
National Hepatology & Tropical Medicine Research...
Cairo University

Unknown

Impact of Interferon Free Regimens in Patients With Chronic HCV and Successfully Treated HCC (FRI-STC)

Hepatocellular Carcinoma | Hepatitis C, Chronic

Egypt
Assiut University

Completed

Predictive Power of Share Wave Fibro Scan in HCC After HCV Infection

Hepatocellular Carcinoma

Egypt
Icahn School of Medicine at Mount Sinai

Completed

Post Sustained Virological Response (SVR) Hepatocellular Carcinoma (HCC) Screening

HCC | Hepatocellular Carcinoma | Hepatitis C | HCV

United States
Hospital Universitario de Valme

Completed

Hepatocellular Carcinoma in HIV-infected Patients (GEHEP-002)

Liver Cirrhosis | Hepatocellular Carcinoma | HIV | Chronic Hepatitis C | Hepatitis B Virus

Spain
University of Arkansas
University of Toronto; University of North Carolina, Chapel Hill; University...

Withdrawn

The Regression of Liver Fibrosis and Risk for Hepatocellular Carcinoma (ROLFH) Study (ROLFH)

Chronic Hepatitis B | Chronic Hepatitis C

United States, Canada
Bayside Health
Merck Sharp & Dohme LLC; Austin Hospital, Melbourne Australia

Withdrawn

HepATocellular Cancer Hcv Therapy Study (HATCHeT)

Hepatocellular Carcinoma | Hepatitis C | Hepatoma | Liver Cell Carcinoma
Karolinska Institutet
AbbVie

Completed

Genome Studies of Hepatocellular Carcinoma Developed in Hepatitis C Patients With Sustained Virological Response (HEPCASUS)

Hepatocellular Carcinoma | Hepatitis C

Sweden
Arbor Research Collaborative for Health
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Health... and other collaborators

Completed

Adult-to-Adult Living Donor Liver Transplantation Study (A2ALL-1)

Hepatocellular Carcinoma | Hepatitis C | Cirrhosis

United States
Dr.Waleed Samir

Unknown

Impact of IL-28B rs12979860 and rs4803217 Gene Polymorphisms Associated With miRNAs Deregulation on HCV-related Hepatocellular Carcinoma

HCV Infection ( Genotype 4)

Egypt
Stanford University
National Cancer Institute (NCI)

Completed

[18F]FMISO PET/CT After Transcatheter Arterial Embolization in Imaging Tumors in Patients With Liver Cancer

Liver Cirrhosis | Adult Liver Carcinoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV

HIV Infection | Metastatic Renal Cell Carcinoma | Anatomic Stage III Breast Cancer AJCC v8 | Recurrent Ovarian Carcinoma | Metastatic Lung Non-Small Cell Carcinoma | Anatomic Stage IV Breast Cancer AJCC v8 | Metastatic Melanoma | Recurrent Head and Neck Carcinoma | Recurrent Renal Cell Carcinoma | Advanced... and other conditions

United States
National Cancer Institute (NCI)

Terminated

EF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or Non-Small Cell Lung Cancer

Fallopian Tube Cancer | Small Intestine Lymphoma | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Stage IV Ovarian Epithelial Cancer | Stage IV Ovarian Germ Cell Tumor | Primary Peritoneal Cavity Cancer | Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small... and other conditions

United States
Istituto Scientifico Romagnolo per lo Studio e...
Merck Sharp & Dohme LLC

Recruiting

Pembrolizumab and Olaparib Treatment of Extensive Small Cell Lung Cancer (ES-SCLC) (THOR)

SCLC,Extensive Stage

Italy
National Cancer Institute (NCI)

Completed

Vaccine Therapy With or Without Sargramostim in Treating Patients With Advanced or Metastatic Cancer

Ovarian Endometrioid Adenocarcinoma | Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Male Breast Cancer | Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Recurrent Breast Cancer | Stage IV Colon Cancer | Stage IV Rectal Cancer and other conditions

United States
Alexandria University

Completed

HCV Related Hepatocellular Carcinoma Recurrence After Directly Acting Antivirals: A Randomized Controlled Trial (RCT)

Hepatocellular Carcinoma | Hepatitis C | Neoplasm Recurrence | Treatment Complication

Egypt
Hospices Civils de Lyon

Completed

Direct-acting Antivirals and Hepatocellular Carcinoma Recurrence (RECAR)

Hepatocellular Carcinoma | Hepatitis C | Direct Acting Antivirals
Zhou Fuxiang

Not yet recruiting

Umbilical Cord Blood Derived MAK Immune Cells Combined With Standard Second-Line Treatments for Hepatobiliary and Pancreatic Malignancies

Stage IV Pancreatic Cancer | Hepatocellular Carcinoma , Cholangiocarcinoma

China
Henan Cancer Hospital

Recruiting

Alotinib Plus Durvalumab-Platinum-Etoposide in First-line Treatment Extensive Small-cell Lung Cancer

SCLC, Extensive Stage

China
National Cancer Institute (NCI)

Completed

Weekly Doses of Cilengitide and Paclitaxel in Treating Patients With Advanced Solid Tumors That Cannot Be Removed by Surgery

Stage IV Breast Cancer | Recurrent Breast Carcinoma | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast Carcinoma | Male Breast Carcinoma | Adult Solid Neoplasm

United States
University of Texas Southwestern Medical Center

Completed

STOP HCC: Mailed HCV Treatment Outreach Program for HCC Prevention

Hepatitis C | HepatoCellular Carcinoma

United States
University of Texas Southwestern Medical Center

Withdrawn

STOP HCC: Mailed HCV Treatment Outreach Program for HCC Prevention for Elevated LFTs (STOP-HCC)

Hepatocellular Carcinoma | Hepatitis C

United States
Massachusetts General Hospital
Conquer Cancer Foundation

Active, not recruiting

Improving Patient and Caregiver Understanding of Risks and Benefits of Immunotherapy for Advanced Cancer (UPLIFT)

Stage IV Non-Small Cell Lung Cancer | Stage IV Bladder Cancer | Stage IV Breast Cancer | Stage IV Melanoma | Immunotherapy | Immune Checkpoint Inhibitors | Stage IV Gastric Cancer | Stage IV Merkel Cell Carcinoma | Stage IV Colorectal Cancer | Stage IV Esophageal Cancer | Advanced Lung Cancer | Stage IV Renal... and other conditions

United States
National Cancer Institute (NCI)

Completed

Trebananib And Temsirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Recurrent Uterine Corpus Sarcoma | Recurrent Renal Cell Carcinoma | Stage III Renal Cell Cancer | Lung Carcinoid Tumor | Stage IV Renal Cell Cancer | Recurrent Digestive System Neuroendocrine Tumor G1 | Adult Solid Neoplasm | Stage IIIB Uterine Sarcoma | Stage IIIC Uterine Sarcoma | Stage IVA Uterine Sarcoma and other conditions

Canada
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Completed

Yttrium Y 90 Resin Microspheres Data Collection in Unresectable Liver Cancer: the RESIN Study (RESiN)

Localized Non-Resectable Adult Liver Carcinoma

United States
St. Louis University

Suspended

Bariatric Embolization of Arteries in Obese Patients With HCC to Allow Salvage Liver Transplantation

Obesity | HCC | Body Weight | Hepatocellular Carcinoma | Hepatitis C | Weight Loss | Cirrhosis

United States

Clinical Trials on BCLC Stage C Adult Hepatocellular Carcinoma

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