Clinical Trials on BRCA Gene Rearrangement
Total 872 results
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Pamela MunsterNational Cancer Institute (NCI)RecruitingBRCA1 Mutation | BRCA2 Mutation | PALB2 Gene Mutation | ATM Gene Mutation | BRCA Mutation | Checkpoint Kinase 2 Gene MutationUnited States
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National Cancer Institute (NCI)CompletedBRCA1 Gene | BRCA2 GeneUnited States
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Rabin Medical CenterUnknownBRCA1 Gene Mutation | BRCA2 Gene MutationIsrael
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University of California, San FranciscoAmerican Cancer Society, Inc.CompletedBRCA1 Gene Mutation | BRCA2 Gene MutationUnited States
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Ohio State University Comprehensive Cancer CenterRecruitingBRCA1 Gene Mutation | BRCA2 Gene MutationUnited States
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University of California, San FranciscoGlaxoSmithKlineRecruitingMetastatic Solid Tumor | BRCA1 Mutation | BRCA2 Mutation | PALB2 Gene Mutation | ATM Gene MutationUnited States
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Rabin Medical CenterCompletedBRCA1 Gene Mutation | BRCA2 Gene MutationIsrael
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PfizerFrench College of General Hospital Pneumologists (CPHG)CompletedNSCLC | Crizotinib | ALK Gene Rearrangement or ROS1 Gene RearrangementFrance
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The First Affiliated Hospital with Nanjing Medical...RecruitingDLBCL | Untreated | MYC Gene RearrangementChina
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Chung-Ang UniversityCompletedBRCA Gene RearrangementKorea, Republic of
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University Medical Center NijmegenRecruitingOvarian Cancer | BRCA1 Gene Mutation | BRCA2 Gene Mutation | RAD51C Gene Mutation | RAD51D Gene Mutation | BRIP1 Gene MutationNetherlands, United States, Belgium, Norway, Poland, Italy, Australia, Mexico, Brazil, Sweden, Uruguay
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Hadassah Medical OrganizationUnknownBRCA1 Gene Mutation | BRCA2 Gene MutationIsrael
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Marc Dall'Era, MDNational Cancer Institute (NCI); Janssen, LPRecruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | Prostate Carcinoma | RAD51C Gene Mutation | BRIP1 Gene Mutation | ATM Gene Mutation | CHEK2 Gene Mutation | NBN Gene Mutation | RAD51 Gene Mutation | CDK12 Gene Mutation | CHEK1 Gene Mutation | DNA Damage Response Gene Mutation | DNA Repair Gene Mutation | FANCA Gene Mutation and other conditionsUnited States
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Okayama UniversityMerck Sharp & Dohme LLCRecruitingBreast Cancer | Breast Neoplasms | Triple Negative Breast Cancer | Triple Negative Breast Neoplasms | BRCA1 Mutation | BRCA2 Mutation | BRCA Mutation | BRCA-Associated Breast CarcinomaJapan
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Steven J Isakoff, MD, PhDDana-Farber Cancer Institute; Beth Israel Deaconess Medical Center; AbbottActive, not recruitingBreast Cancer | Metastatic Breast Cancer | BRCA1 Gene Mutation | brca2 Gene MutationUnited States
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Tianjin Medical University Second HospitalRecruitingSolid Tumor | FGF Receptor Gene Mutation | FGF Amplification | FGF Receptor Gene Family Rearrangement | FGF Receptor Gene TranslocationChina
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PfizerMedivation, Inc.; Myriad Genetic Laboratories, Inc.TerminatedBreast Neoplasms | BRCA 1 Gene Mutation | BRCA 2 Gene MutationUnited States, Spain, United Kingdom, Germany, France
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Institut für Klinische Krebsforschung IKF GmbH...Incyte Biosciences International SàrlRecruitingIntrahepatic Cholangiocarcinoma | FGFR2 Gene Mutation | FGFR2 Gene Translocation | FGFR2 Gene RearrangementGermany
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)RecruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast Carcinoma | MLH1 Gene Mutation | RAD51C Gene Mutation | RAD51D Gene Mutation | BRIP1 Gene Mutation | PALB2 Gene Mutation | BARD1 Gene Mutation | MSH2 Gene Mutation | MSH6... and other conditionsUnited States
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Beth Israel Deaconess Medical CenterJohns Hopkins University; Dana-Farber Cancer Institute; AstraZenecaActive, not recruitingMetastatic Breast Cancer | Invasive Breast Cancer | BRIP1 Gene Mutation | PALB2 Gene Mutation | ATM Gene Mutation | CHEK2 Gene Mutation | NBN Gene Mutation | RAD51 Gene Mutation | Somatic Mutation Breast Cancer (BRCA1) | Somatic Mutation Breast Cancer (BRCA2)United States
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PfizerMedivation, Inc.CompletedBreast Neoplasms | BRCA 1 Gene Mutation | BRCA 2 Gene MutationKorea, Republic of, United States, Australia, Spain, Belgium, France, Ireland, Taiwan, Poland, Germany, Israel, Brazil, United Kingdom, Italy, Russian Federation, Ukraine
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Betta Pharmaceuticals Co., Ltd.UnknownLung Cancer | ROS1 Gene RearrangementChina
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AstraZenecaMerck Sharp & Dohme LLC; Myriad Genetic Laboratories, Inc.Active, not recruitingBreast Cancer Metastatic | BRCA 1 Gene Mutation | BRCA 2 Gene MutationItaly, Spain, United States, Czechia, Romania, France, Korea, Republic of, United Kingdom, Hungary, Japan, Peru, Poland, Russian Federation, Turkey, China, Taiwan, Bulgaria, Switzerland, Mexico
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)CompletedInvasive Breast Carcinoma | HER2/Neu Negative | Breast Adenocarcinoma | Deleterious BRCA1 Gene Mutation | Deleterious BRCA2 Gene MutationUnited States
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Relay Therapeutics, Inc.Active, not recruitingCholangiocarcinoma | Intrahepatic Cholangiocarcinoma | FGFR2 Gene Mutation | FGFR2 Amplification | FGFR2 Gene Fusion/Rearrangement | FGFR2 Gene Translocation | FGFR2 Gene Activation | Other Solid Tumors, AdultUnited States, France, Italy, United Kingdom, Korea, Republic of, Spain, Taiwan, Sweden, Germany, Netherlands, Singapore, Australia, Hong Kong
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | Metastatic Malignant Neoplasm | Advanced Malignant Neoplasm | Recurrent Malignant Neoplasm | Refractory Malignant Neoplasm | PALB2 Gene Mutation | ATM Gene MutationUnited States
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Jiangxi Qingfeng Pharmaceutical Co. Ltd.UnknownBreast Cancer Metastatic | BRCA 1 Gene Mutation | BRCA 2 Gene MutationChina
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Weill Medical College of Cornell UniversityBasser Research Center for BRCARecruiting
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University of PennsylvaniaRecruiting
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Azienda Ospedaliera Universitaria Policlinico Paolo...Unknown
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Centre Leon BerardRecruitingCancer | Cancer Metastatic | ALK Fusion Protein Expression | FGFR2 Gene Translocation | FGFR3 Gene Translocation | NTRK Family Gene Mutation | Gene Fusion | ROS1 Gene Translocation | NTRK Gene Fusion Overexpression | ATIC-ALK Fusion Protein Expression | BCR-FGFR1 Fusion Protein Expression | COL1A1-PDGFB Fusion... and other conditionsFrance, Denmark, Netherlands, Austria, Germany, Italy, United Kingdom, Czechia, Poland, Slovenia, Spain
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Dana-Farber Cancer InstituteJohns Hopkins University; GlaxoSmithKline; Translational Breast Cancer Research...RecruitingBreast Cancer | Stage I Breast Cancer | Stage II Breast Cancer | HER2-negative Breast Cancer | Stage III Breast Cancer | Deleterious PALB2 Gene Mutation | Germline BRCA1 Gene Mutation | Germline BRCA2 Gene MutationUnited States
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Taiho Oncology, Inc.Active, not recruitingAdvanced Cholangiocarcinoma | FGFR2 Gene RearrangementsUnited States, Spain, United Kingdom, Australia, Taiwan, Italy, France, Korea, Republic of, Belgium, Japan, Thailand, Germany, Brazil, Peru, Portugal, Argentina, Hong Kong, Mexico, Netherlands, Poland
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Qian QinJanssen, LP; UT Southwestern Comprehensive Cancer CenterNot yet recruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | BRIP1 Gene Mutation | PALB2 Gene Mutation | CHEK2 Gene Mutation | FANCA Gene Mutation | RAD51B Gene Mutation | RAD54L Gene Mutation | Metastatic Hormone-sensitive Prostate Cancer (mHSPC) | Deleterious HRR Gene Mutation
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Memorial Sloan Kettering Cancer CenterUniversity of Pennsylvania; University of California, Los Angeles; Dana-Farber... and other collaboratorsActive, not recruiting
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Severance HospitalSamsung Medical Center; Asan Medical Center; Kyungpook National University Chilgok...RecruitingBreast Neoplasms | Benign Breast Disease | Germline BRCA1 Gene Mutation | Germline BRCA2 Gene Mutation | Germline Mutation AbnormalityKorea, Republic of
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Hellenic Cooperative Oncology GroupActive, not recruitingProstate Cancer Recurrent | Prostate Cancer Metastatic | Mutation | Germline BRCA1 Gene Mutation | Germline BRCA2 Gene MutationGreece
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PfizerTerminatedLocally Advanced or Metastatic Solid Tumors | Genes, BRCA 1United States, Belgium, Spain, Denmark, Japan, France, Italy, Netherlands, United Kingdom
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Southwest Oncology GroupNational Cancer Institute (NCI)CompletedBRCA1 Gene Mutation | BRCA2 Gene Mutation | Recurrent Squamous Cell Lung Carcinoma | Stage IV Squamous Cell Lung Carcinoma AJCC v7 | BRIP1 Gene Mutation | PALB2 Gene Mutation | ATM Gene Mutation | ATR Gene Mutation | CHEK2 Gene Mutation | NBN Gene Mutation | RAD51 Gene Mutation | CHEK1 Gene Mutation | FANCA Gene... and other conditionsUnited States, Canada
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European Institute of OncologyCompletedBRCA1 Mutation | BRCA2 Mutation | Psychosocial FactorsItaly
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Intergroupe Francophone de Cancerologie ThoraciquePfizerCompletedALK Gene Rearrangement Positive | Non-small Cell Lung Cancer Metastatic | ROS-1 Gene Rearrangement PositiveFrance
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Taiho Oncology, Inc.RecruitingAdvanced Cholangiocarcinoma | FGFR2 Fusions | Gene RearrangementUnited States, Korea, Republic of, Spain, Japan, Portugal, Italy, China, Argentina, Brazil, Poland, Australia
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Fondazione Policlinico Universitario Agostino Gemelli...RecruitingGenetic Predisposition to Disease | Gene Rearrangement | Genome InstabilityItaly
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Shandong UniversityFudan University; Chinese Nutrition SocietySuspended
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Memorial Sloan Kettering Cancer CenterRecruitingBRCA1 Mutation | BRCA2 Mutation | APC Gene Mutation | MLH1 Gene Mutation | RAD51C Gene Mutation | RAD51D Gene Mutation | BRIP1 Gene Mutation | PALB2 Gene Mutation | PTEN Gene Mutation | ATM Gene Mutation | CHEK2 Gene Mutation | BARD1 Gene Mutation | MSH2 Gene Mutation | MSH6 Gene Mutation | PMS2 Gene Mutation | POLD1 Gene... and other conditionsUnited States
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nVision MedicalCompletedBRCA1 Mutation | BRCA2 Mutation | Atypia Suspicious for MalignancyUnited States
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National Cancer Institute (NCI)CompletedAdult Solid Neoplasm | BRCA1 Mutation Carrier | BRCA2 Mutation CarrierUnited States
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Women's College HospitalCanadian Institutes of Health Research (CIHR); London Health Sciences Centre; H. Lee Moffitt Cancer Center and Research Institute and other collaboratorsUnknownBreast Cancer | Ovarian Cancer | BRCA1 Gene Mutation | BRCA2 Gene MutationCanada
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Abramson Cancer Center at Penn MedicineRecruiting
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University Hospital, MontpellierCompleted