Clinical Trials on BRCA1 Gene Mutation
Total 1890 results
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Turning Point Therapeutics, Inc.TerminatedNon-Small Cell Lung Cancer | NSCLC | Non Small Cell Lung Cancer | Advanced Solid Tumor | Metastatic Solid Tumor | ALK Gene MutationUnited States, Australia, Korea, Republic of
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Escape Bio, Inc.Momentum Pharma; Science 37TerminatedPatients With Parkinson's Disease (PD) Caused by the p.Gly2019Ser (G2019S) Pathogenic Mutation of the Leucine-Rich Repeat Kinase 2 (LRRK2) GeneUnited States
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Shirish GadgeelMerck Sharp & Dohme LLCWithdrawnNon Small Cell Lung Cancer | PD-L1 Gene Mutation | Advanced Lung Non-Small Cell Carcinoma
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TriHealth Inc.TriHealth Cancer Institute; TriHealth Surgical Institute; TriHealth Ultrasound... and other collaboratorsWithdrawnMelanoma (Skin) | Tumor Skin | BRAF Gene Mutation | Melanoma Stage IIIb-IVM1a | Metastasis SkinUnited States
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ABM Therapeutics CorporationRecruitingAdvanced Solid Tumor | RAS Mutation | NF1 Mutation | RAF MutationUnited States
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National Cancer Institute (NCI)CompletedRecurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Breast Carcinoma | Ovarian Carcinoma | Pancreatic Carcinoma | Prostate Carcinoma | Recurrent Breast Carcinoma | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative... and other conditionsUnited States
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Associazione Italiana per lo Studio del PancreasRecruitingLynch Syndrome | BRCA1 Mutation | BRCA2 Mutation | Familial Pancreatic Cancer | Hereditary Pancreatitis | Peutz-Jeghers Syndrome | FAMMM - Familial Atypical Mole Malignant Melanoma SyndromeItaly
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Massachusetts General HospitalAgios Pharmaceuticals, Inc.CompletedIDH1 Mutation Myeloid NeoplasmsUnited States
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Nanfang Hospital, Southern Medical UniversityRecruitingAcute Lymphoblastic Leukemia | Philadelphia Chromosome | Adult ALL | Philadelphia-Positive ALL | IKZF1 Gene MutationChina
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Alliance for Clinical Trials in OncologyNational Cancer Institute (NCI); GlaxoSmithKline; Genentech, Inc.; Brain Science...RecruitingIntracranial Meningioma | Recurrent Meningioma | NF2 Gene MutationUnited States
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SwanBio Therapeutics, Inc.Active, not recruitingAMN | AMN Gene Mutation | X-ALDUnited States, Netherlands, Germany
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Henan Cancer HospitalFundamenta Therapeutics, Ltd.Not yet recruitingAllogeneic, CAR-T, Protein Sequestration, Non-gene EditedChina
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Zhongnan HospitalActive, not recruitingPharmacokinetic | Abiraterone Acetate | Plasma Concentration | Gene Polymorphism | Metabolic AnalysisChina
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Wageningen UniversityDutch Diabetes Research FoundationCompletedExercise | Muscle | Gene Expression | MyokineNetherlands
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Guangdong Provincial People's HospitalShanghai Junshi Bioscience Co., Ltd.RecruitingNon-Small Cell Lung Cancer | BRAF V600 Mutation | MET Amplification | MET Exon 14 Skipping Mutation | RET Driver Mutation | Erb-B2 Receptor Tyrosine Kinase Exon 20 MutationChina
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Boehringer IngelheimRecruitingSolid Tumor, KRAS MutationUnited States, Taiwan, Japan
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Southwest Oncology GroupNational Cancer Institute (NCI)CompletedCCND1 Gene Amplification | CCND2 Gene Amplification | CCND3 Gene Amplification | CDK4 Gene Amplification | Recurrent Squamous Cell Lung Carcinoma | Stage IV Squamous Cell Lung Carcinoma AJCC v7United States
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Medical University of GrazCompletedNFAT Regulated Gene Expression in Tacrolimus Treated PatientsAustria
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Intergroupe Francophone de Cancerologie ThoraciqueCompletedNon-small Cell Lung Cancer | Anaplastic Lymphoma Kinase Gene MutationFrance
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Calithera Biosciences, IncTerminatedNon-Small Cell Lung Cancer | Squamous Non-small-cell Lung Cancer | NFE2L2 Gene Mutation | Squamous Non-Small Cell Neoplasm of LungUnited States
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Hellenic Cooperative Oncology GroupCompletedNon Small Cell Lung Cancer | EGF-R Positive Non-Small Cell Lung Cancer | EGFR Gene Mutation
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Regeneron PharmaceuticalsNot yet recruitingAmyotrophic Lateral Sclerosis (ALS) | Mutation in the Superoxide Dismutase-1 (SOD1) Gene
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Memorial Sloan Kettering Cancer CenterRecruitingBladder Cancer | Recurrent Bladder Cancer | FGFR3 Gene MutationUnited States
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University of ChicagoRecruitingBreast Cancer | Head and Neck Cancer | Gastrointestinal Cancer | Dihydropyrimidine Dehydrogenase Deficiency | UGT1A1 Gene MutationUnited States
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Hospices Civils de LyonRecruitingFamilial Mediterranean Fever | MEFV Gene MutationFrance
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Heinrich-Heine University, DuesseldorfCelgene Corporation; Koordinierungszentrum für Klinische Studien DüsseldorfActive, not recruitingMyelodysplastic Syndromes | Leukemia, Myeloid, Acute | Chronic Myelomonocytic Leukemia | IDH2 Gene Mutation | IDH2 R172 | IDH2 R140Germany
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Intergroupe Francophone de Cancerologie ThoraciqueCompletedNon Small Cell Lung Cancer Metastatic | HER2 Gene Mutation | Non Small Cell Lung Cancer Stage IIIFrance
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Roswell Park Cancer InstituteCelgeneWithdrawnRecurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | IDH2 Gene Mutation | Blasts Under 5 Percent of Peripheral Blood White Cells | Bone Marrow Blasts Decreased by 50 Percent or More Compared to Pretreatment LevelUnited States
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Boehringer IngelheimActive, not recruitingSolid Tumors, KRAS Mutation; SOS1United States, Netherlands, Germany
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Indonesia UniversityDr Cipto Mangunkusumo General HospitalCompletedin Vitro Fertilization | Acupuncture | Oocyte Maturation | BCL2 Gene mRNA OverexpressionIndonesia
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Daping Hospital and the Research Institute of Surgery...Not yet recruitingNon Small Cell Lung Cancer | EGFR Gene Mutation | Non-small Cell Lung Cancer Stage IV | Non Small Cell Lung Cancer Stage IIIA
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National Cancer Institute (NCI)Active, not recruitingKRAS Gene Mutation | Recurrent Lung Non-Small Cell Carcinoma | Stage IV Lung Non-Small Cell Cancer AJCC v7United States
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Liberating Technologies, Inc.Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaboratorsCompletedAmputation | Prosthesis User | Amputation; Traumatic, Hand | Amputation, CongenitalUnited States
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Suzhou Zelgen Biopharmaceuticals Co.,LtdRecruitingSolid Tumor | KRAS Mutation-Related TumorsChina
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Ruijin HospitalRecruitingP53 Mutation | Myeloid Malignancy | MDS | AmlChina
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Blueprint Medicines CorporationCompletedSystemic Mast Cell Activation | KIT D816V MutationUnited States, France, United Kingdom, Italy, Germany, Belgium, Spain, Switzerland
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Georgetown UniversityImmune System Key LtdRecruitingSolid Tumor | KRAS Mutation-Related TumorsUnited States
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BayerRecruitingLocally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene FusionUnited States, Austria, Denmark, Germany, Italy, Norway, Spain, United Kingdom, Brazil, Russian Federation, Switzerland, Taiwan, Canada, China, Australia, Greece, Belgium, Sweden, Korea, Republic of, France, Argentina, Finland, Ireland and more
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BayerCompletedWound Healing | Gene Expression | Cell ProliferationGermany
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Shirley Ryan AbilityLabEunice Kennedy Shriver National Institute of Child Health and Human Development...Active, not recruitingAmputation | Amputation; Traumatic, Limb | Upper Limb Amputation at the Hand | Upper Limb Amputation at the WristUnited States
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N.N. Petrov National Medical Research Center of...RecruitingMelanoma | Lung Cancer | Pancreas Cancer | Refractory Cancer | Colorectal Cancer Recurrent | RAS Mutation | Ras (Kras or Nras) Gene MutationRussian Federation
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Kura Oncology, Inc.RecruitingAcute Myeloid Leukemia | Acute Myeloid Leukemia, in Relapse | Myeloid Sarcoma | Acute Myeloid Leukemia Recurrent | Mixed Phenotype Acute Leukemia | Mixed Lineage Acute Leukemia | Refractory AML | NPM1 Mutation | Mixed Lineage Leukemia Gene Mutation | AML With Mutated NPM1 | KMT2ArUnited States
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Medipol UniversityRecruitingEvaluation of Functionality of Amputees According to the Medicare Functional K Classification SystemAmputation | Amputation; Traumatic, Leg, LowerTurkey
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AstraZenecaCompletedEGFR Mutation Status in aNSCLC PatientsKorea, Republic of, Russian Federation, Malaysia, China, Australia, Taiwan, Thailand, Indonesia, Singapore
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Jiangsu vcare pharmaceutical technology co., LTDCompletedLocally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene FusionChina
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University of Eastern FinlandDSM Nutritional Products, Inc.CompletedVitamin D Receptor Target Gene Expression | Serum 25(OH)D ConcentrationFinland
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M.D. Anderson Cancer CenterSyndax PharmaceuticalsNot yet recruitingLeukemia | HOX GeneUnited States
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Abramson Cancer Center of the University of PennsylvaniaCompletedCandidates for BRCA 1/2 Genetic TestingUnited States
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Hacettepe UniversityCompleted
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University Health Network, TorontoPfizerRecruitingNon-squamous Non-small-cell Lung Cancer | Stage IV Non-small Cell Lung Cancer | ROS1 Gene Rearrangement | MET Activating Mutation | MET AmplificationCanada