Clinical Trials on BRCA2 Gene in United Kingdom
Total 386 results
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Pamela MunsterNational Cancer Institute (NCI)RecruitingBRCA1 Mutation | BRCA2 Mutation | PALB2 Gene Mutation | ATM Gene Mutation | BRCA Mutation | Checkpoint Kinase 2 Gene MutationUnited States
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National Cancer Institute (NCI)CompletedBRCA1 Gene | BRCA2 GeneUnited States
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Ohio State University Comprehensive Cancer CenterRecruitingBRCA1 Gene Mutation | BRCA2 Gene MutationUnited States
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University of California, San FranciscoAmerican Cancer Society, Inc.CompletedBRCA1 Gene Mutation | BRCA2 Gene MutationUnited States
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University of California, San FranciscoGlaxoSmithKlineRecruitingMetastatic Solid Tumor | BRCA1 Mutation | BRCA2 Mutation | PALB2 Gene Mutation | ATM Gene MutationUnited States
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University Medical Center NijmegenRecruitingOvarian Cancer | BRCA1 Gene Mutation | BRCA2 Gene Mutation | RAD51C Gene Mutation | RAD51D Gene Mutation | BRIP1 Gene MutationNetherlands, United States, Belgium, Norway, Poland, Italy, Australia, Mexico, Brazil, Sweden, Uruguay
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Steven J Isakoff, MD, PhDDana-Farber Cancer Institute; Beth Israel Deaconess Medical Center; AbbottActive, not recruitingBreast Cancer | Metastatic Breast Cancer | BRCA1 Gene Mutation | brca2 Gene MutationUnited States
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Marc Dall'Era, MDNational Cancer Institute (NCI); Janssen, LPRecruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | Prostate Carcinoma | RAD51C Gene Mutation | BRIP1 Gene Mutation | ATM Gene Mutation | CHEK2 Gene Mutation | NBN Gene Mutation | RAD51 Gene Mutation | CDK12 Gene Mutation | CHEK1 Gene Mutation | DNA Damage Response Gene Mutation | DNA Repair Gene Mutation | FANCA Gene Mutation and other conditionsUnited States
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University of PennsylvaniaRecruiting
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Weill Medical College of Cornell UniversityBasser Research Center for BRCARecruiting
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Memorial Sloan Kettering Cancer CenterUniversity of Pennsylvania; University of California, Los Angeles; Dana-Farber... and other collaboratorsActive, not recruiting
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)CompletedInvasive Breast Carcinoma | HER2/Neu Negative | Breast Adenocarcinoma | Deleterious BRCA1 Gene Mutation | Deleterious BRCA2 Gene MutationUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)RecruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast Carcinoma | MLH1 Gene Mutation | RAD51C Gene Mutation | RAD51D Gene Mutation | BRIP1 Gene Mutation | PALB2 Gene Mutation | BARD1 Gene Mutation | MSH2 Gene Mutation | MSH6... and other conditionsUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | Metastatic Malignant Neoplasm | Advanced Malignant Neoplasm | Recurrent Malignant Neoplasm | Refractory Malignant Neoplasm | PALB2 Gene Mutation | ATM Gene MutationUnited States
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Beth Israel Deaconess Medical CenterJohns Hopkins University; Dana-Farber Cancer Institute; AstraZenecaActive, not recruitingMetastatic Breast Cancer | Invasive Breast Cancer | BRIP1 Gene Mutation | PALB2 Gene Mutation | ATM Gene Mutation | CHEK2 Gene Mutation | NBN Gene Mutation | RAD51 Gene Mutation | Somatic Mutation Breast Cancer (BRCA1) | Somatic Mutation Breast Cancer (BRCA2)United States
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nVision MedicalCompletedBRCA1 Mutation | BRCA2 Mutation | Atypia Suspicious for MalignancyUnited States
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Dana-Farber Cancer InstituteJohns Hopkins University; GlaxoSmithKline; Translational Breast Cancer Research...RecruitingBreast Cancer | Stage I Breast Cancer | Stage II Breast Cancer | HER2-negative Breast Cancer | Stage III Breast Cancer | Deleterious PALB2 Gene Mutation | Germline BRCA1 Gene Mutation | Germline BRCA2 Gene MutationUnited States
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National Cancer Institute (NCI)CompletedAdult Solid Neoplasm | BRCA1 Mutation Carrier | BRCA2 Mutation CarrierUnited States
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Royal Marsden NHS Foundation TrustCompletedMRI | BRCA1 Mutation | BRCA2 Mutation | MammographyUnited Kingdom
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Abramson Cancer Center at Penn MedicineRecruiting
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PfizerMedivation, Inc.; Myriad Genetic Laboratories, Inc.TerminatedBreast Neoplasms | BRCA 1 Gene Mutation | BRCA 2 Gene MutationUnited States, Spain, United Kingdom, Germany, France
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Southwest Oncology GroupNational Cancer Institute (NCI)CompletedBRCA1 Gene Mutation | BRCA2 Gene Mutation | Recurrent Squamous Cell Lung Carcinoma | Stage IV Squamous Cell Lung Carcinoma AJCC v7 | BRIP1 Gene Mutation | PALB2 Gene Mutation | ATM Gene Mutation | ATR Gene Mutation | CHEK2 Gene Mutation | NBN Gene Mutation | RAD51 Gene Mutation | CHEK1 Gene Mutation | FANCA Gene... and other conditionsUnited States, Canada
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Memorial Sloan Kettering Cancer CenterRecruitingBRCA1 Mutation | BRCA2 Mutation | APC Gene Mutation | MLH1 Gene Mutation | RAD51C Gene Mutation | RAD51D Gene Mutation | BRIP1 Gene Mutation | PALB2 Gene Mutation | PTEN Gene Mutation | ATM Gene Mutation | CHEK2 Gene Mutation | BARD1 Gene Mutation | MSH2 Gene Mutation | MSH6 Gene Mutation | PMS2 Gene Mutation | POLD1 Gene... and other conditionsUnited States
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Weill Medical College of Cornell UniversityCompletedBreast Cancer | Gynecologic Cancer | BRCA1 Mutation | BRCA2 MutationUnited States
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AstraZenecaMerck Sharp & Dohme LLC; Myriad Genetic Laboratories, Inc.Active, not recruitingBreast Cancer Metastatic | BRCA 1 Gene Mutation | BRCA 2 Gene MutationItaly, Spain, United States, Czechia, Romania, France, Korea, Republic of, United Kingdom, Hungary, Japan, Peru, Poland, Russian Federation, Turkey, China, Taiwan, Bulgaria, Switzerland, Mexico
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PfizerMedivation, Inc.CompletedBreast Neoplasms | BRCA 1 Gene Mutation | BRCA 2 Gene MutationKorea, Republic of, United States, Australia, Spain, Belgium, France, Ireland, Taiwan, Poland, Germany, Israel, Brazil, United Kingdom, Italy, Russian Federation, Ukraine
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Institute of Cancer Research, United KingdomCancer Research UK; National Institute for Health Research, United KingdomRecruitingProstate Cancer | BRCA1 Mutation | BRCA2 MutationUnited Kingdom
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Massachusetts General HospitalCompletedBreast Cancer | BRCA1 Mutation | BRCA2 MutationUnited States
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NYU Langone HealthWithdrawnBreast Cancer | BRCA1 Mutation | BRCA2 MutationUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingHereditary Breast and Ovarian Cancer Syndrome | Premenopausal | Deleterious BARD1 Gene Mutation | Deleterious BRCA1 Gene Mutation | Deleterious BRCA2 Gene Mutation | Deleterious BRIP1 Gene Mutation | Deleterious EPCAM Gene Mutation | Deleterious MLH1 Gene Mutation | Deleterious MSH2 Gene Mutation | Deleterious... and other conditionsUnited States
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Institute of Cancer Research, United KingdomRoyal Marsden NHS Foundation Trust; Cancer Research UK; Ronald and Rita McAulay...Active, not recruitingProstate Cancer in BRCA1 and BRCA2 CarriersUnited Kingdom
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Gynecologic Oncology GroupNational Cancer Institute (NCI)WithdrawnBreast Carcinoma | BRCA1 Mutation Carrier | BRCA2 Mutation CarrierUnited States
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Roswell Park Cancer InstituteAstraZenecaActive, not recruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Ovarian Serous AdenocarcinomaUnited States
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Gynecologic Oncology GroupNational Cancer Institute (NCI)UnknownBreast Cancer | brca1 Mutation Carrier | brca2 Mutation CarrierUnited States
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University College London HospitalsCompletedBreast Cancer | Hereditary Breast/Ovarian Cancer (brca1, brca2) | brca1 Mutation Carrier | brca2 Mutation CarrierAustralia, Israel, United Kingdom, Spain, Sweden, Portugal
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PfizerTerminatedLocally Advanced or Metastatic Solid Tumors | Genes, BRCA 1United States, Belgium, Spain, Denmark, Japan, France, Italy, Netherlands, United Kingdom
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City of Hope Medical CenterNational Cancer Institute (NCI)Active, not recruitingBreast Cancer | brca1 Mutation Carrier | brca2 Mutation CarrierUnited States
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Georgetown UniversityGeorge Washington UniversityEnrolling by invitation
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University of WashingtonActive, not recruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | Castration-Resistant Prostate Carcinoma | Homologous Recombination Deficiency | PSA Progression | Stage IV Prostate Adenocarcinoma AJCC v7 | Castration Levels of Testosterone | ATM Gene Mutation | Prostate Carcinoma Metastatic in the Bone | PSA Level Greater...United States
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Southwest Oncology GroupNational Cancer Institute (NCI)CompletedBreast Cancer | brca1 Mutation Carrier | brca2 Mutation CarrierUnited States
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Columbia UniversityAmerican Cancer Society, Inc.CompletedBreast Cancer | Ovarian Cancer | BRCA1 Mutation | BRCA2 MutationUnited States
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Tesaro, Inc.European Organisation for Research and Treatment of Cancer - EORTC; Breast... and other collaboratorsTerminatedOvarian Neoplasms | BRCA1 Gene Mutation | BRCA2 Gene Mutation | Neoplasms, Breast | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | Carcinoma of BreastUnited States, Spain, Belgium, Israel, United Kingdom, Italy, Poland, Canada, Hungary, Netherlands, France, Portugal, Greece, Iceland
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National Cancer Institute (NCI)CompletedBRCA1 Gene Mutation | BRCA2 Gene Mutation | Recurrent Breast Carcinoma | Estrogen Receptor Negative | Estrogen Receptor Positive | HER2/Neu Negative | Progesterone Receptor Negative | Progesterone Receptor Positive | Triple-Negative Breast Carcinoma | Stage IV Breast Cancer AJCC v6 and v7 | Stage IIIB Breast... and other conditionsUnited States
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Abramson Cancer Center at Penn MedicineActive, not recruitingAdvanced Breast Cancer | Metastatic Breast Cancer | BRCA1 Mutation | BRCA2 Mutation | Locally Advanced Breast CancerUnited States
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AstraZenecaCompletedOvarian Neoplasms | BRCA1 Protein | BRCA2 ProteinNetherlands, Belgium, United Kingdom, Poland
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingObesity | Overweight | Ductal Breast Carcinoma In Situ | Deleterious BRCA1 Gene Mutation | Deleterious BRCA2 Gene Mutation | Premalignant LesionUnited States
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Centre Leon BerardRecruitingCancer | Cancer Metastatic | ALK Fusion Protein Expression | FGFR2 Gene Translocation | FGFR3 Gene Translocation | NTRK Family Gene Mutation | Gene Fusion | ROS1 Gene Translocation | NTRK Gene Fusion Overexpression | ATIC-ALK Fusion Protein Expression | BCR-FGFR1 Fusion Protein Expression | COL1A1-PDGFB Fusion... and other conditionsFrance, Denmark, Netherlands, Austria, Germany, Italy, United Kingdom, Czechia, Poland, Slovenia, Spain
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Mayo ClinicAllerganCompletedNeoplasms | Pain, Postoperative | Breast Cancer | Breast Diseases | BRCA1 Mutation | BRCA2 MutationUnited States
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Ohio State University Comprehensive Cancer CenterCompletedBRCA1 Gene Mutation | BRCA2 Gene Mutation | Ductal Breast Carcinoma in Situ | Atypical Ductal Breast Hyperplasia | Lobular Breast Carcinoma in SituUnited States
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The National Institute of LymphologyThe DrMarga Practice Group; The Center for Restorative Breast Surgery, LLCUnknownBreast Cancer | Hereditary Breast/Ovarian Cancer (brca1, brca2) | Congenital Lymphedema | Acquired LymphedemaUnited States