Clinical Trials on Bacteria Infection Mechanism

Total 61433 results

Centre of Postgraduate Medical Education

Unknown

Cryptic Bacteria of the Thyroid Tissue as a Possible Cause of the Pathology of This Organ

Bacteria Infection Mechanism

Poland
The University of Queensland
Merck Sharp & Dohme LLC

Withdrawn

Ceftolozane-tazobactam Versus Meropenem for ESBL and AmpC-producing Enterobacterales Bloodstream Infection (MERINO III)

Bacteremia Caused by Gram-Negative Bacteria

Spain, Australia, Singapore, Italy, Saudi Arabia
Seoul National University Hospital

Completed

Clinical Usefulness of Therapeutic Drug Monitoring of Colistin in Patients Treated With Colistin.

Multidrug-resistant Gram-negative Bacteria Infection

Korea, Republic of
Gamaleya Research Institute of Epidemiology and...

Not yet recruiting

Clinical Trial to Study the Efficacy and Safety of Fluorothiazinone (N.F. Gamaleya NRCEM) in Prophylaxis of Nosocomial Bacterial Infections With Participation of Patients on MV

Gram-Negative Bacterial Infections | Bacteremia Caused by Gram-Negative Bacteria | Gram Negative Pneumonia
Nanjing First Hospital, Nanjing Medical University

Recruiting

Fucoidan Assisted Eradication of Helicobacter Pylori

Helicobacter Pylori Infection | Intestinal Bacteria Flora Disturbance

China
University Hospital, Basel, Switzerland
Stiftung Forschung Infektionskrankheiten, Basel, Switzerland

Completed

Simplified GBS Screening and Prevalence of ESBL in Pregnant Women

Group B Streptococcal Infection | Infection Due to ESBL Bacteria

Switzerland
University Hospital of Cologne
Charite University, Berlin, Germany; University Hospital Tuebingen; University... and other collaborators

Completed

Antibiotic Stewardship and Infection Control in Patients at High Risk of Developing Infection by Clostridium Difficile, Vancomycin-Resistant Enterococci or Multi-Resistant Gram-Negatives (ABSOLUTE)

Clostridium Difficile Infection | Nosocomial Infection | VRE Infection | MRGN Bacteria

Germany
Johann DD Pitout
Merck Sharp & Dohme LLC

Completed

International Travel and the Spread of Extended-spectrum Beta-lactamase-producing Escherichia Coli

Infection Due to Resistant Bacteria

Canada
Assistance Publique - Hôpitaux de Paris
Advanz Pharma; Centre Hospitalier de Perigueux; CHU de Nantes; Centre National...

Recruiting

Dalbavancin Versus Standard Antibiotic Therapy for Catheter-related Bloodstream Infections Due to Staphylococcus Aureus (DALICATH)

Staphylococcus Aureus Infection | Catheter Bacteremia

France
University of Geneva, Switzerland
Centre Hospitalier Universitaire Vaudois; Cantonal Hospital of St. Gallen

Completed

Antibiotic Durations for Gram-negative Bacteremia (PIRATE)

Bacteraemia Caused by Gram-Negative Bacteria

Switzerland
Thomas Benfield

Recruiting

Shortened Antibiotic Treatment of 5 Days in Gram-negative Bacteremia (GNB5)

Urinary Tract Infection Bacterial | Gram-negative Bacteremia

Denmark
University of Michigan
Wayne State University; Henry Ford Health System; Agency for Healthcare Research... and other collaborators

Completed

Pulsed UV Xenon Disinfection to Prevent Resistant Healthcare Associated Infection

Clostridium Difficile Infection | Healthcare Associated Infection | Infection Due to Multidrug Resistant Bacteria

United States
JESUS RODRIGUEZ BAÑO

Completed

Impact of Specific Antimicrobials and MIC Values on the Outcome of Bloodstream Infections Due to Extended-spectrum Beta-lactamase (ESBL) or Carbapenemase-producing Enterobacteriaceae: an Observational Multinational Study (INCREMENT)

Clinically Significant Bacteremia

Spain
University College, London
King's College London; Rambam Health Care Campus; University of Melbourne; Menzies... and other collaborators

Not yet recruiting

18-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in S. Aureus Bacteraemia (PET-SAB)

Sepsis | Staphylococcus Aureus Infection | Bloodstream Infection | Staphylococcus Aureus Bacteremia | Sepsis Bacterial | Staphylococcus Aureus Septicemia | Staph Sepsis
Connie Price
United States Department of Defense; Accelerate Diagnostics, Inc.

Completed

Study of Accuracy of New Diagnostic Technology to Determine Guide Rapid Antibiotic Treatment for Serious Infections (RAMPED)

Infection | Skin and Subcutaneous Tissue Bacterial Infections | Healthcare-associated Infection | Infection Due to Resistant Bacteria

United States
Denver Health and Hospital Authority
United States Department of Defense; Accelerate Diagnostics, Inc.

Completed

Study of Accuracy of New Diagnostic Technology to Guide Rapid Antibiotic Treatment for Serious Infections

Skin and Subcutaneous Tissue Bacterial Infections | Healthcare-associated Infection | INFECTIONS | Infection Due to Resistant Bacteria

United States
Vanderbilt University Medical Center

Recruiting

Effect of Direct-from-blood Bacterial Testing on Antibiotic Administration and Clinical Outcomes

Bloodstream Infection | Vancomycin | MRSA Bacteremia | Sepsis Bacterial

United States
MJM Bonten
Paris 12 Val de Marne University

Completed

Ecological Effects of Decolonisation Strategies in Intensive Care (RGNOSIS)

ICU-ecology (Multidrug Resistant Bacteria) | ICU-acquired Bacteraemia

Belgium, Spain, United Kingdom, Italy, Portugal, Slovenia
University Hospital, Tours

Completed

How to Reduce Unnecessary Blood Cultures: Construction and Validation of a Predictive Score for Blood Culture Positivity in Intensive Care (PROBIty)

Bacteremia | Infection, Bacterial | Infection, Fungal

France
The Methodist Hospital Research Institute
M.D. Anderson Cancer Center; National Institute of Allergy and Infectious Diseases... and other collaborators

Recruiting

Dynamics of Colonization and Infection by Multidrug-Resistant Pathogens in Immunocompromised and Critically Ill Patients (DYNAMITE)

Antibiotic Resistant Infection | Clostridium Difficile | Antimicrobial Drug Resistance | Carbapenem-Resistant Enterobacteriaceae Infection | Vancomycin Resistant Enterococci Infection | Vancomycin-Resistant Enterococcal Infection | Carbapenem Resistant Bacterial Infection | Extended Spectrum Beta-Lactamase...

United States
Rambam Health Care Campus
Canadian Institutes of Health Research (CIHR); Hadassah Medical Organization; McGill University Health Centre/Research Institute of the McGill University Health Centre and other collaborators

Recruiting

PipEracillin Tazobactam Versus mERoPENem for Treatment of Bloodstream Infections Caused by Cephalosporin-resistant Enterobacteriaceae (PETERPEN) (PETERPEN)

Bacteremia | Enterobacteriaceae Infections | Beta Lactam Resistant Bacterial Infection

Israel, Canada
Phramongkutklao College of Medicine and Hospital

Completed

Ertapenem for Initial Empirical Treatment of Third Generation Cephalosporin Resistant Enterobacteriaceae Bacteremia

Bacteremia | Infection, Bacterial

Thailand
ExThera Medical Corporation

Completed

Safety Evaluation of Seraph® 100 to Reduce Bacteremia in Patients on Hemodialysis

Bacteremia | Bacterial Infection

Germany
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); Parexel; BioMé...

Recruiting

Fast Antibiotic Susceptibility Testing for Gram Negative Bacteremia Trial (FAST)

Bloodstream Infection | Gram-negative Bacteremia

Israel, India, Spain, Greece
University Hospital, Strasbourg, France

Completed

Cefepime vs. Carbapenems for Treating AmpC β-lactamase-producing Enterobacteriaceae Bloodstream Infections (CARBAPENEM)

Bacteremia

France
ContraFect

Completed

A Placebo-Controlled, Dose-Escalating Study to Examine the Safety and Tolerability of Single Intravenous Doses of CF-301 in Healthy Subjects

Staphylococcus Aureus Bloodstream Infections (BSI; Bacteremia)

United States
Hospital Moinhos de Vento

Terminated

Seven Versus 14 Days of Antibiotic Therapy for Multidrug-resistant Gram-negative Bacilli Infections (OPTIMISE)

Sepsis | Gram-Negative Bacterial Infections | Bacteremia | Severe Infection | Bloodstream Infection | Acinetobacter Infections | Pseudomonas Aeruginosa | Human | Carbapenem-Resistant Enterobacteriaceae Infection | Carbapenem Resistant Bacterial Infection

Brazil
Pfizer

Terminated

Linezolid in the Treatment of Hemodialysis Patients With Catheter-Related Gram-Positive Bloodstream Infections

Gram-Positive Bacterial Infections | Bacteremia

Slovakia, India, United States, Colombia, Italy, Israel, Poland
Kirby Institute

Not yet recruiting

PATH Study: People With Injecting Related Infections: Assessing Treatment Outcomes for Those Who Are Hospitalised. (PATH)

Invasive Fungal Infections | Infection, Bacterial | Infection, Fungal | Injection Site Infection | Infection, Soft Tissue | Invasive Bacterial Infection
MicroPhage, Inc.

Completed

MicroPhage S. Aureus / MSSA / MRSA Blood Culture Beta Trial

Sepsis | Bacteremia | Infection | Staphylococcal Infection

United States
Rambam Health Care Campus
Hadassah Medical Organization; Rabin Medical Center; The Chaim Sheba Medical...

Suspended

PipEracillin/Tazobactam Versus mERoPENem for Treatment of AmpC Producing Blood Stream Infections (SPICE-M)

Bacteremia | Enterobacteriaceae Infections | Beta Lactam Resistant Bacterial Infection

Israel
London North West Healthcare NHS Trust

Completed

Bacteriology of sUrGical Site INfection Following Surgery for Intestinal Failure (BUGS-IN-IF)

Surgical Wound Infection | Intestinal Fistula | Surgical Site Infection | Intestinal Disease | Bacteria Infection Mechanism

United Kingdom
Hunter Holmes Mcguire Veteran Affairs Medical Center
Centers for Disease Control and Prevention; Sage Products, Inc.

Unknown

Multicenter Trial of Daily Chlorhexidine Bathing to Reduce Nosocomial Infections (CBET)

MRSA Infection | MRSA Colonization | VRE Infection | VRE Colonization | Nosocomial Bacteremia

United States
University of Pittsburgh

Completed

Optimizing Dosing of Colistin for Infections Resistant to All Other Antibiotics, Approved NIH Protocol Dated 12.06.07(DMID Protocol #07-0036)

Bacteremia | Pseudomonas Infections

United States
University of Manitoba
Winnipeg Regional Health Authority; MED XL Inc

Completed

Efficacy and Safety of an Ethanol/Sodium Citrate Locking Solution: A Pilot Study

Bacteremia | Catheter Related Infection

Canada
Spanish Network for Research in Infectious Diseases
European Society of Clinical Microbiology and Infectious Diseases

Completed

Impact of Specific Antimicrobials and MIC Values on the Outcome of Bloodstream Infections Due to ESBL- or Carbapenemase-producing Enterobacterales in Solid Organ Transplantation: an Observational Multinational Study. (INCREMENT-SOT)

Pathologic Processes | Sepsis | Systemic Inflammatory Response Syndrome | Inflammation | Bacterial Infections | Bacteremia | Infection | Organ Transplantation | Clinically Significant Bacteremia

Spain
Murdoch Childrens Research Institute
University of Otago; Sydney Children's Hospitals Network; Royal Children's Hospital and other collaborators

Completed

Improving Dosing of Vancomycin in Young Infants With Infections (VANCAPP)

Sepsis | Bacteremia | Infection

Australia
Murdoch Childrens Research Institute
Royal Children's Hospital; Royal Hospital For Women

Completed

RCT of Continuous Versus Intermittent Infusion of Vancomycin in Neonates

Sepsis | Bacteremia | Infection

Australia
Murdoch Childrens Research Institute
Sydney Children's Hospitals Network; Royal Children's Hospital; Monash Health; Royal...

Not yet recruiting

Improving Therapeutic Drug Monitoring and Dosing for Vancomycin in Young Infants With Infections (VANCAPP) (Part 2) (VANCAPP)

Infections | Sepsis | Bacteremia

Australia
Hamilton Health Sciences Corporation

Unknown

UGIST: Ultrasound Guided Internal Jugular Short-Term Central Venous Catheters Tunneling (UGIST)

Bacteremia | Infection

Canada
University Hospital, Tours

Not yet recruiting

Development and Qualification of Methods for Analyzing the Mucosal Immune Response to COVID-19 (MUCOVID)

Certain Disorders Involving the Immune Mechanism

France
Hunter Holmes Mcguire Veteran Affairs Medical Center
Johns Hopkins University; Washington University School of Medicine; Weill Medical... and other collaborators

Completed

The Impact of Chlorhexidine-Based Bathing on Nosocomial Infections

MRSA Infection | MRSA Colonization | VRE Infection | VRE Colonization | Nosocomial Bacteremia | Nosocomial Fungemia

United States
M.D. Anderson Cancer Center
Theravance Biopharma

Completed

Study to Evaluate the Safety and Efficacy of Telavancin in the Treatment of Gram Positive Bloodstream Infections in Cancer Patients

Bacteremia | Infection

United States
University of Wisconsin, Madison

Completed

The Effects of Mindfulness Training on Pain Regulation, Negative Affect, Attention, and Social Stress

Focus on Pain Regulation Mechanisms | Social Stress Mechanisms | Basic Affective Mechanisms | Attention Mechanisms | Brain Mechanisms | Immune Mechanisms | Endocrine Mechanisms

United States
Johns Hopkins Bloomberg School of Public Health

Completed

Etiology, Prevention and Treatment of Neonatal Infections in the Community

Infectious Disease | Bacterial Infection

Bangladesh
Fundación Pública Andaluza para la gestión de la...
Spanish Clinical Research Network - SCReN; CIBER (Infectious diseases)

Recruiting

Efficacy and Safety of 7 Versus 14 Days of Antibiotic Treatment for Pseudomonas Aeruginosa Bacteraemia (SHORTEN2)

Bloodstream Infection

Spain
Singapore General Hospital
National Medical Research Council (NMRC), Singapore

Recruiting

Evaluating a Novel Individualised Treatment Strategy for Carbapenem-Resistant Gram-Negative Bacteria Infections

Antibiotic Therapy

Singapore
Eye & ENT Hospital of Fudan University
Soochow University

Recruiting

Novel Antisense Oligonucleotide Eye Drops for Treating Antibiotic-Resistant Bacterial Keratitis (ASOTARI)

Eye Diseases | Corneal Diseases | Sensation Disorders | Vision Disorders | Blindness | Infections, Bacterial | Bacterial Keratitis | Antibiotic-resistant Bacteria | Antisense Peptide Nucleic Acid | Antibacterial Therapy

China
Pfizer

Completed

Antibiotic Treatment for Infections of Short Term In-dwelling Vascular Catheters Due to Gram Positive Bacteria

Bacterial Infections | Gram-Positive Bacterial Infections | Bacteremia
National University Hospital, Singapore

Unknown

Early Infectious Disease Consultations in Staphylococcus Aureus Bacteremia

Staphylococcus Aureus Bacteremia

Singapore

Clinical Trials on Bacteria Infection Mechanism

Sponsors and Collaborators

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Drug Interventions

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CROs in Montenegro

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