Clinical Trials on Bacterial Disease in United Kingdom

Total 147396 results

Imperial College London
Hammersmith Hospitals NHS Trust

Completed

Oral Antibiotic Treatment at Home Instead of Intravenous Treatment in Hospital for Resistant Gram Positive Infections

Staphylococcal Infections | Gram-positive Bacterial Infections

United Kingdom
Imperial College London

Recruiting

Addition of Probenecid to Penicillin-V Therapy (ADDPROPEN)

Infection, Bacterial

United Kingdom
Danisco
Community Pharmacology Services Ltd

Completed

PreFem: "What Happens to the Vaginal Microbiota When a BV Infection is Treated With Metronidazole?" (PreFem)

Bacterial Vaginosis

United Kingdom
Novartis Vaccines

Completed

Safety, Tolerability and Immunogenicity of Two Different Formulations of Meningococcal B Recombinant Vaccine, When Administered to Healthy Infants

Meningococcal Disease

United Kingdom
Novartis Vaccines

Completed

Extension Study Evaluating Antibody Persistence and Safety, Tolerability and Immunogenicity of a Booster Dose of Novartis rMenB±OMV NZ Vaccine in Healthy UK Children Who Previously Received Three Doses of the Same Vaccine

Meningococcal Disease

United Kingdom
Novartis Vaccines

Completed

Extension Study Evaluating Antibody Persistence and Safety, Tolerability and Immunogenicity of Booster Doses of Novartis rMenB±OMV NZ Vaccine in Healthy UK Children Who Previously Received One or Four Doses of the Same Vaccine

Meningococcal Disease

United Kingdom
Statens Serum Institut
Imperial College London

Completed

Safety and Immunogenicity of a Chlamydia Vaccine CTH522 (CHLM-02)

Trachoma

United Kingdom
University of Oxford

Completed

The Microbiology of Pleural Infection (TORPIDS)

Pleural Infection | Pleural Infection Bacterial

United Kingdom
Chiron Corporation

Unknown

Kinetic of Immune Memory Response After Re-Vaccination With Meningococcal Vaccine

Meningococcal Disease; Meningococcal Meningitis

United Kingdom
University of Southampton
University Hospital Southampton NHS Foundation Trust

Unknown

A Controlled Study to Assess Safety, Colonisation and Immunogenicity of Reconstituted Lyophilised Neisseria Lactamica (Lac5-Nasal)

Meningitis, Bacterial

United Kingdom
University of Southampton
University Hospital Southampton NHS Foundation Trust

Completed

Defining the Immune Response to Nasopharyngeal Colonisation by the Commensal Neisseria Lactamica (Lac-7)

Meningitis, Bacterial

United Kingdom
University of Oxford
GlaxoSmithKline; Oxford University Hospitals NHS Trust

Completed

Can we Reduce the Number of Vaccine Injections for Children? (MALTA)

Invasive Meningococcal Disease

United Kingdom
Niso Biomed S.R.L.

Unknown

Endofaster Test for Helicobacter Pylori Detection in Patients on Proton Pump Inhibitor Therapy

Helicobacter Infections

United Kingdom
St George's, University of London
King's College London; Statens Serum Institut

Not yet recruiting

The LISA (Lactoferrin InStead of Antibiotics/Antifungals) Feasibility Study (LISA)

Bacterial Vaginosis | Candida Vaginal

United Kingdom
University of Southampton
University Hospital Southampton NHS Foundation Trust

Completed

Challenge of the Nasopharynx With Neisseria Lactamica Expressing the Meningococcal Protein Neisseria Adhesin A (NadA) (NadA-Lac4)

Meningitis, Bacterial | Neisseria Infection

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Unknown

Feasibility Studies to Inform Novel Proposals to Avert Community-Based Antimicrobial Resistance Spread

Gram-Negative Bacterial Infections

United Kingdom
University of Oxford
Mason Medical Research Trust

Completed

Pneumococcal Adult Kinetics Study - Understanding the B Cell Response to Pneumococcal Vaccines

Pneumococcal Disease

United Kingdom
Nottingham University Hospitals NHS Trust

Terminated

Ursodeoxycholic Acid in C. Difficile Infection

Clostridioides Difficile Infection

United Kingdom
Barts & The London NHS Trust

Unknown

Novel Biomarkers to Predict Outcome in Clostridium Difficile Infection

Clostridium Difficile Infection

United Kingdom
St George's, University of London
Public Health England

Recruiting

Propositive (Protecting Positive People From Meningococcal Infection) Follow-up Study

HIV/AIDS | Meningococcal Disease

United Kingdom
Forest Laboratories

Completed

Efficacy and Safety of Quadruple Therapy in Eradication of H. Pylori: A Comparison to Triple Therapy

Helicobacter Infections

United Kingdom
Cwm Taf University Health Board (NHS)
Cardiff University

Completed

UROGEN WELL D-ONE : Evaluation of a Novel Diagnostic for Sexually Transmitted Bacterial Infections

Sexually Transmitted Diseases, Bacterial | Antimicrobial Resistance | Bacterial Urinary Tract Infection

United Kingdom
St George's, University of London

Completed

Community-Based Trial of Screening for Chlamydia Trachomatis to Prevent Pelvic Inflammatory Disease (POPI)

Chlamydia Infections | Pelvic Inflammatory Disease

United Kingdom
University of Oxford

Recruiting

OptiGon - Optimising Laboratory Assays for Immune Responses to Gonococcus

Gonorrhea

United Kingdom
Novartis Vaccines
Novartis

Completed

B Cell Response to a Primary and a Booster Course of the Novartis Meningococcal ACWY Conjugate Vaccine in Healthy Infants

Meningococcal Disease

United Kingdom
NeuTec Pharma

Completed

Aurograb and Vancomycin in MRSA Infection

Staphylococcal Infections

United Kingdom
Public Health England
Institute of Child Health; National Institute of Biological Standards and Control

Completed

Study to Evaluate the Immune Response of United Kingdom (UK) Infants Receiving DTaP/Hib/IPV, Meningococcal C Conjugate and Pneumococcal Conjugate Vaccines, Antibody Persistence and Responses to Booster Doses in the Second Year of Life (Sched2)

Pneumococcal Infections | Meningococcal Infections

United Kingdom
St George's, University of London

Unknown

Evaluation of Safety and Immunogenicity of Meningococcal B and Meningococcal ACWY Vaccine in at Risk Population (ProPositive)

HIV Infections | Hiv | Meningitis, Meningococcal

United Kingdom
University Hospital Southampton NHS Foundation...
University of Southampton

Unknown

A Study Assessing Colonisation & Immunogenicity After Nasal Inoculation With N. Lactamica and Eradication on Day 4 or 14 (Lac-3)

Meningitis, Meningococcal

United Kingdom
Genocea Biosciences, Inc.

Completed

Safety, Tolerability, and Efficacy Study of Prophylactic S. Pneumoniae Vaccine Following Challenge With S. Pneumoniae

Pneumococcal Infections | Pneumonia, Pneumococcal

United Kingdom
Statens Serum Institut
Imperial College London

Completed

Safety of Chlamydia Vaccine CTH522 in Healthy Women Aged 18 to 45 Years

Chlamydia Trachomatis

United Kingdom
University of Oxford
Norwegian Institute of Public Health; Wellcome Trust

Completed

MenPF-1 - A New Vaccine Against Meningococcal Disease

Serogroup B Meningococcal Disease

United Kingdom
Public Health England

Withdrawn

Host-pathogen Interactions in Meningococcal Disease: Finding the Key That Fits the Lock (Lock and Key)

Meningitis

United Kingdom
Destiny Pharma Plc

Completed

Study to Assess Eradication of Nasal Carriage of Staphylococcus Aureus (SA) With Mupirocin (Bactroban 2% Nasal Ointment)

Staphylococcal Infection

United Kingdom
Helen Reynolds
Liverpool University Hospitals NHS Foundation Trust

Completed

The Effect of Intermittent Rifampicin on Raltegravir (RIFRAL)

HIV | Tuberculosis

United Kingdom
Queen Mary University of London
Barts & The London NHS Trust; Quadram Institute Bioscience

Recruiting

Accuracy of Metagenomic Blood Sampling to Identify Pathogen in Infective Endocarditis Patients (AMetIP)

Infective Endocarditis

United Kingdom
St George's, University of London
University of Nottingham; Medical Research Council; Public Health England

Recruiting

Development of a Serocorrelate of Protection Against Invasive Group B Streptococcus Disease (iGBS3)

Streptococcus Agalactiae Infection

United Kingdom
University of Edinburgh
NHS Lothian

Completed

Virtual Observed Therapy for Patients With Tuberculosis

Tuberculosis

United Kingdom
St George's Healthcare NHS Trust

Unknown

Genome Sequencing of Multidrug Resistant Tuberculosis (MDR TB) in Sputum (MDRTB01)

Tuberculosis

United Kingdom
University of Oxford

Completed

Safety of Tuberculosis Vaccine, MVA85A, Administered by the Intramuscular Route and the Intradermal Route

Tuberculosis

United Kingdom
University of Oxford

Completed

A Study to Quantify Bacille Calmette Guerin (BCG) and Characterise the Immune Response After BCG Vaccination

Tuberculosis

United Kingdom
Barts & The London NHS Trust
Imperial College London; Wellcome Trust; University of Cape Town; Newham Chest... and other collaborators

Completed

Effects of Vitamin D Supplementation on Antimycobacterial Immunity

Tuberculosis

United Kingdom
MJM Bonten
Paris 12 Val de Marne University

Completed

Ecological Effects of Decolonisation Strategies in Intensive Care (RGNOSIS)

ICU-ecology (Multidrug Resistant Bacteria) | ICU-acquired Bacteraemia

Belgium, Spain, United Kingdom, Italy, Portugal, Slovenia
Stuart Bond

Active, not recruiting

ElastoMeric Infusion Pumps for Hospital AntibioTICs (EMPHATIC)

Infection, Bacterial

United Kingdom
GlaxoSmithKline

Completed

First Time in Human (FTIH) Safety and Pharmacokinetics (PK) Study of GSK3036656 in Healthy Subjects

Tuberculosis

United Kingdom
Destiny Pharma Plc

Completed

Study of the Nasal Decolonisation of Staphylococcus Aureus (SA) and the Safety and Tolerability of XF-73 Nasal Gel in Healthy Subjects

Staphylococcus Aureus Infection

United Kingdom
University of Oxford

Completed

A Phase I Study to Assess the Safety and Immunogenicity of Tuberculosis (TB) Vaccine Candidates FP85A and MVA85A

Tuberculosis

United Kingdom
Barts & The London NHS Trust
NHS Research and Development

Unknown

Can Screening People Registering With Primary Care Improve the Detection of Tuberculosis?

Tuberculosis

United Kingdom
University of Oxford

Completed

Safety of Tuberculosis Vaccine, MVA85A, Administered by the Aerosol Route and the Intradermal Route

Tuberculosis

United Kingdom
University Hospitals Bristol and Weston NHS Foundation...
Public Health England; University of Bristol; Novartis Vaccines; North Bristol...

Completed

Regulation of Mucosal Immune Response to Systemic MenB Vaccine

Meningococcal Infections

United Kingdom

Clinical Trials on Bacterial Disease in United Kingdom

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