Clinical Trials on Benign Centrally-Located Intracranial Tumors

Total 3904 results

National Cancer Institute (NCI)

Completed

Pomalidomide in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

Neurofibromatosis Type 1 | Recurrent Primary Central Nervous System Neoplasm | Refractory Primary Central Nervous System Neoplasm | Recurrent Childhood Brain Stem Glioma | Recurrent Childhood Visual Pathway Glioma

United States
Bundang CHA Hospital

Unknown

ESWT for Shoulder Pain in Patients With Brain Damage

Stroke | Brain Tumor | Brain Damage, Hypoxic | ICH

Korea, Republic of
Klinikum Stuttgart
Klinikum Kassel GmbH (COSS-Biobank)

Not yet recruiting

Registry For Children, Adolescents And Adults With Osteosarcoma And Biologically Related Bone Sarcomas (COSS-Registry)

Osteosarcoma | High Grade Sarcoma | Recurrent Osteosarcoma | Bone Sarcoma | Undifferentiated Pleomorphic Sarcoma | Bone Tumor | Extraskeletal Osteosarcoma | Osseous Sarcoma | Parosteal Osteosarcoma | Osteoblastic Osteosarcoma | Chondroblastic Osteosarcoma | Fibroblastic Osteosarcoma | Conventional Osteosarcoma | Conventional... and other conditions
Klinikum Oldenburg gGmbH
Deutsche Gesellschaft für Kinderendokrinologie und Diabetologie (DGKED); Deutsche... and other collaborators

Recruiting

Multicenter Registry for Patients With Childhood.Onset Craniopharyngioma, Xanthogranuloma, Cysts of Rathke's Pouch, Meningioma, Pituitary Adenoma, Arachnoid Cysts

Obesity | Craniopharyngioma

Germany
University of Zurich

Recruiting

Cerebrovascular Disease: Quality of Life (CODE: QoL) (CODE:QoL)

Cerebrovascular Disorders | Quality of Life | Stress | Transient Ischemic Attack | Caregiver Burden | Sexual Behavior | Stroke, Acute | Intracerebral Hemorrhage | Incontinence, Urinary | Cortisol Excess

Switzerland
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI); Highlight Therapeutics

Active, not recruiting

Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue Sarcoma

Leiomyosarcoma | Malignant Peripheral Nerve Sheath Tumor | Synovial Sarcoma | Undifferentiated Pleomorphic Sarcoma | Undifferentiated High Grade Pleomorphic Sarcoma of Bone | Myxofibrosarcoma | Stage II Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage III Soft Tissue Sarcoma of the... and other conditions

United States
Stanford University

Completed

Valganciclovir (Valcyte) for Chronic Fatigue Syndrome Patients Who Have Elevated Antibody Titers Against Human Herpes Virus 6 (HHV-6)and Epstein-Barr Virus (EBV)

Chronic Fatigue Syndrome

United States
National Cancer Institute (NCI)

Recruiting

Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma

Lynch Syndrome | Malignant Glioma | Recurrent Childhood Ependymoma | Recurrent Medulloblastoma | Refractory Ependymoma | Refractory Medulloblastoma | Recurrent Diffuse Intrinsic Pontine Glioma | Refractory Diffuse Intrinsic Pontine Glioma | Recurrent Brain Neoplasm | Refractory Brain Neoplasm | Constitutional...

United States, Canada
Julie Krystal
Janssen Pharmaceuticals

Recruiting

A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas

Glioblastoma Multiforme | Gliosarcoma | Anaplastic Astrocytoma | Pleomorphic Xanthoastrocytoma | Pilocytic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Low-grade Glioma | DIPG | Brainstem Glioma | Optic Nerve Glioma | Pilomyxoid Astrocytoma | Glioma, Astrocytic

United States
National Cancer Institute (NCI)

Completed

Temsirolimus and Perifosine in Treating Patients With Recurrent or Progressive Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Oligodendroglioma | Recurrent Adult Brain Neoplasm

United States
MedSIR
Daiichi Sankyo

Recruiting

HER3-DXd in Breast Cancer and NSCLC Brain Metastases and Solid Tumor Leptomeningeal Disease (TUXEDO-3)

Metastatic Breast Cancer | Solid Tumor, Adult | Advanced Non-Small Cell Squamous Lung Cancer

Spain, Austria
Centre Hospitalier Universitaire Dijon

Completed

Quantitative and Functional Study of TH17 Lymphocytes in Horton's Disease (HD)

Infectious Disease | Solid Tumor | Hemopathy | Horton's Disease | Neoplasia

France
Barts & The London NHS Trust
Harvard Medical School (HMS and HSDM); Brigham and Women's Hospital

Unknown

Neurosurgical Transitional Care Programme (TCP)

Brain Diseases | Spinal Diseases | Brain Cancer | Brain Tumor | Surgery | Spinal Stenosis | Aneurysm | Fusion of Spine | Brain Metastases | Spinal Fusion | Trigeminal Neuralgia | Brain Tumor, Recurrent | Hydrocephalus | Spinal Cord Neoplasms | Brain Lesion | SPINAL Fracture | Brain Pathology | Spinal Instability | Spinal Curvature | Chiari; Net and other conditions

United Kingdom
University of Michigan Rogel Cancer Center

Completed

Study of High-Dose Chemotherapy With Bone Marrow or Stem Cell Transplant for Rare Poor-Prognosis Cancers

Nasopharyngeal Cancer | Fibrosarcoma | Wilms Tumor | Brain Tumor, Recurrent | Carcinoma, Round Cell

United States
University Hospital Inselspital, Berne

Recruiting

Prognosis of Cerebral Small Vessel Disease - a Prospective Cohort Study (PRO-SVD)

Cerebral Amyloid Angiopathy | Cadasil | Small Vessel Cerebrovascular Disease | CAA - Cerebral Amyloid Angiopathy

Switzerland
Aneurin Bevan University Health Board

Unknown

MORbidity PRevalence Estimate In StrokE (MORe PREcISE)

Depression | Stroke | Anxiety | Dysphagia | Cerebral Infarction | Mild Cognitive Impairment | Hemiplegia | Aphasia | Stroke, Ischemic | Stroke Hemorrhagic | Hemiparesis | CVA (Cerebrovascular Accident) | Dysarthria | Intracerebral Hemorrhage | Hemianopia | Hemispatial Neglect | CVA; Sequelae

United Kingdom
Esraa Mostafa Ahmed Abdel Aal

Not yet recruiting

Inflammatory Biomarkers in Psychogenic Non-epileptic Seizure (seizure)

Localization-Related (Focal) (Partial) Idiopathic Epilepsy and Epileptic Syndromes With Seizures of Localized Onset | TRAIL: Tumor Necrosis Factor Related Apoptosis Inducing Ligand MCP-2 | MCP-2: Monocyte Chemo-attractant Protein-2
National Cancer Institute (NCI)

Completed

17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Advanced Epithelial Cancer, Malignant Lymphoma, or Sarcoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Scott R. Plotkin, MD, PhD
Takeda; National Comprehensive Cancer Network; The Children's Tumor Foundation

Recruiting

Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2) (INTUITT-NF2)

Ependymoma | Meningioma | Neurofibromatosis Type 2 | Vestibular Schwannoma | Non-vestibular Schwannoma

United States
Children's Hospital Medical Center, Cincinnati
AstraZeneca

Active, not recruiting

Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors (SEL-TH-1601)

Glioma | Ependymoma | Meningioma | Neurofibromatosis 2 | Vestibular Schwannoma

United States
Leiden University Medical Center

Terminated

Electrophysiology of the Human Pituitary Gland

Pituitary Adenoma | Pituitary Tumor | Diabetes Insipidus Cranial Type | Endocrine; Deficiency

Netherlands
Seoul National University Hospital

Recruiting

Seoul National University Pituitary Disease Cohort Study (SNU-PIT)

Acromegaly | Cushing's Disease | Pituitary Tumor | Prolactinoma | Pituitary Disease | Central Diabetes Insipidus | Pituitary Incidentaloma | Pituitary Stalk Compression Hyperprolactinaemia

Korea, Republic of
Memorial Sloan Kettering Cancer Center

Completed

Phase II Trial of Stereotactic Radiosurgery Boost Following Surgical Resection for Brain Metastases

Melanoma | Sarcoma | Cervical Cancer | Breast Cancer | Pancreatic Cancer | Lung Cancer | Rectal Cancer | Prostate Cancer | Bladder Cancer | Colon Cancer | Brain Metastasis | Testicular Cancer | HEENT Cancer

United States
Technical University of Munich
Charite University, Berlin, Germany

Recruiting

Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis (ME/CFS) Registry and Biobank, COVID-19, SARS-CoV-2 (MECFS-R)

Fatigue Syndrome, Chronic | SARS CoV 2 Infection | ME/CFS | Epstein-Barr Virus

Germany
Aesculap AG

Recruiting

MiDura-Study (Neuro-Patch in Duraplasty) (MiDura)

Meningioma | Craniotomy | Hydrocephalus | Spinal Surgery | Tumor, Brain | Chiari Malformation | Vascular Malformation | Tethered Cord | Dural Fistula | Duraplasty

Germany
Assistance Publique - Hôpitaux de Paris

Completed

Coproporphyrine Isomers and Methotrexate Elimination (COMETH)

Lymphoma, Large B-Cell, Diffuse | Central Nervous System Neoplasms | Burkitt Lymphoma | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

France
Virginia Commonwealth University
United States Department of Defense

Recruiting

CALM: Managing Distress in Malignant Brain Cancer

Brain Cancer | Brain Tumor | Metastatic Lung Cancer | Metastatic Breast Cancer | Metastatic Melanoma | Brain Metastases | Metastatic Colon Cancer | Metastatic Kidney Cancer

United States
University College, London

Completed

Risk Factors in the Initial Presentation of Specific Cardiovascular Disease Syndromes

Heart Diseases | Cardiovascular Diseases | Heart Failure | Ischemic Stroke | Peripheral Arterial Disease | Transient Ischemic Attack | Cardiac Arrest | Subarachnoid Hemorrhage | Cerebrovascular Accident | Acute Myocardial Infarction | Unstable Angina | Abdominal Aortic Aneurysm | Chronic Stable Angina | Sudden Coronary... and other conditions
University Hospital, Strasbourg, France

Recruiting

Regulating Emotions and Behaviors After Brain Injury (GREMO-LCA)

Encephalitis | Meningitis | Acquired Brain Injury | Cerebral Anoxia | Stroke/ Cerebrovascular Accident (Ischemic or Hemorrhagic) | Brain Tumor (After Recovery)

France
Ann & Robert H Lurie Children's Hospital of Chicago
Northwestern University; Florida State University

Withdrawn

Increasing Healthcare Engagement Via Routine Vaccination Among Young Black Men Who Have Sex With Men

Hepatitis A | Meningitis | HPV - Anogenital Human Papilloma Virus Infection
Assiut University

Unknown

DBS in the Treatment of Intractable Movement Disorders

Parkinson Disease, Essential Tremors and Dystonia
The University of Hong Kong

Recruiting

Translational Immunodiagnostics in Stroke (TrImS) (TrImS)

Atrial Fibrillation | Acute Ischemic Stroke | Transient Ischemic Attacks | Cardioembolic Stroke | Large-Artery Atherosclerosis (Embolus/Thrombosis) | Haemorrhagic Stroke | Small Vessel Disease | Stroke of Other Determined Etiology | Stroke of Undetermined Etiology | Stroke of Anterior Cerebral Artery | Stroke... and other conditions

China
University College, London
Medical Research Council; Wellcome Trust; National Institute for Health Research...

Unknown

Serum Uric Acid Levels and Onset of Cardiovascular Diseases: a CALIBER Study

Myocardial Infarction | Heart Failure | Ischemic Stroke | Peripheral Arterial Disease | Atrial Fibrillation | Cardiac Arrest | Subarachnoid Hemorrhage | Stable Angina | Unstable Angina | Abdominal Aortic Aneurysm | Intracerebral Hemorrhage | Unheralded Coronary Heart Disease Death | Transient Ischaemic Attack
University College, London
London School of Hygiene and Tropical Medicine; Wellcome Trust; National Institute...

Completed

Ethnicity and Onset of Cardiovascular Disease: A CALIBER Study

Myocardial Infarction | Heart Failure | Stroke | Ischemic Stroke | Peripheral Arterial Disease | Transient Ischemic Attack | Coronary Heart Disease | Cardiac Arrest | Stable Angina Pectoris | Unstable Angina | Sudden Cardiac Death | Abdominal Aortic Aneurysm | Intracerebral Haemorrhage | Subarachnoid Haemorrhage
Ohio State University

Completed

Physiological Brain Atlas Development

Depression | Parkinson Disease | Obsessive Compulsive Disorder | Dystonia | Tremors

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

A Prospective Study to Evaluate Clinical Outcomes in Anti-LGI1 Encephalitis

Autoimmune Encephalitis | Leucine-Rich Glioma Inactivated 1 Autoimmune Encephalitis

China
UCB Biopharma SRL

Terminated

A Study to Test the Efficacy, Safety, and Pharmacokinetics of Rozanolixizumab in Adult Study Participants With Leucine-Rich Glioma Inactivated 1 Autoimmune Encephalitis

Leucine-Rich Glioma Inactivated 1 Autoimmune Encephalitis

United States, Australia, Belgium, France, Germany, Italy, Netherlands, Spain, United Kingdom
Taproot Health

Recruiting

The Registry of Oncology Outcomes Associated With Testing and Treatment (ROOT)

Melanoma | Sarcoma | Kidney Cancer | Adenocarcinoma | Renal Cell Carcinoma | Cervical Cancer | Acute Myeloid Leukemia | Stomach Cancer | Breast Cancer | Head and Neck Neoplasms | Nasopharyngeal Carcinoma | Glioblastoma | Astrocytoma | Multiple Myeloma | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Small Bowel Cancer and other conditions

United States
Celldex Therapeutics

Completed

A Study of CDX-1127 (Varlilumab) in Patients With Select Solid Tumor Types or Hematologic Cancers

Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | CD27 Expressing B-cell Malignancies for Example Hodgkin's Lymphoma | Marginal Zone B Cell Lymphoma) | Any T-cell Malignancy | Solid Tumors (Metastatic Melanoma, Renal (Clear) Cell Carcinoma | Hormone-refractory Prostate Adenocarcinoma, Ovarian... and other conditions

United States
University of Pennsylvania

Not yet recruiting

Using the EHR to Advance Genomic Medicine Across a Diverse Health System

Parkinson Disease | Alzheimer Disease | ALS | Polyneuropathies | Frontotemporal Dementia | Pheochromocytoma | Thoracic Aortic Aneurysm | Paraganglioma | Genetic Predisposition | Cardiomyopathy Non-ischemic
Loma Linda University

Completed

Measuring Cerebral Blood Flow Using Pseudo-continuous Arterial Spin Labeling Perfusion Magnetic Resonance Imaging

Multiple Sclerosis | Traumatic Brain Injury | Alzheimer's Disease | Tumor
University College, London
Wellcome Trust; National Institute for Health Research, United Kingdom

Unknown

Heart Rate and Initial Presentation of Cardiovascular Diseases (Caliber)

Myocardial Infarction | Heart Failure | Stroke | Ischemic Stroke | Peripheral Arterial Disease | Transient Ischemic Attack | Stable Angina Pectoris | Unstable Angina | Abdominal Aortic Aneurysm | Intracerebral Haemorrhage | Subarachnoid Haemorrhage | Coronary Heart Disease NOS | Cardiac Arrest, Sudden Cardiac Death and other conditions

United Kingdom
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Project: Every Child for Younger Patients With Cancer

Malignant Solid Neoplasm | Neuroendocrine Neoplasm | Myeloproliferative Neoplasm | Desmoid Fibromatosis | Lymphoproliferative Disorder | Carcinoma In Situ | Central Nervous System Neoplasm | Ganglioneuroma | Congenital Mesoblastic Nephroma | Childhood Immature Teratoma | Childhood Langerhans Cell Histiocytosis and other conditions

United States, Puerto Rico, Canada, Australia, New Zealand, Saudi Arabia
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

WSD0922-FU for the Treatment of Glioblastoma, Anaplastic Astrocytoma, or Non-small Cell Lung Cancer With Central Nervous System Metastases

Metastatic Lung Non-Small Cell Carcinoma | Anaplastic Astrocytoma, IDH-Wildtype | Glioblastoma, IDH-Wildtype | Metastatic Malignant Neoplasm in the Central Nervous System

United States
St. Justine's Hospital
CHU de Quebec-Universite Laval; Montreal Children's Hospital of the MUHC

Active, not recruiting

Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway.

Low-grade Glioma | Plexiform Neurofibroma | Central Nervous System Glioma

Canada
Hoffmann-La Roche

Terminated

A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors (ALpha-T)

Digestive System Diseases | Gastrointestinal Diseases | Melanoma | Sarcoma | Neoplasms | Respiratory Tract Diseases | Neoplasms by Site | Gastrointestinal Neoplasms | Digestive System Neoplasms | Head and Neck Neoplasms | Respiratory Tract Neoplasms | Thoracic Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms and other conditions

United States
Celgene

Completed

Study of CC-122 to Evaluate the Safety, Tolerability, and Effectiveness for Patients With Advanced Solid Tumors, Non-Hodgkin's Lymphoma, or Multiple Myeloma

Lymphoma | Lymphoma, Large B-Cell, Diffuse | Glioblastoma | Multiple Myeloma | Primary Central Nervous System Lymphoma | Pleiotropic Pathway Modifier

United States, Spain, Belgium, France, Italy
Georgetown University
Solstice Neurosciences

Completed

Myobloc Atrophy Study (MAS)

Stroke | Brain Injury | Tumor | Spinal Cord Injury (SCI) | Spasticity Secondary to Either a Disorder or Trauma

United States
University College, London
Wellcome Trust; National Institute for Health Research, United Kingdom

Unknown

Social Deprivation and Initial Presentation of 12 Cardiovascular Diseases: a CALIBER Study (IP4)

Myocardial Infarction | Heart Failure | Stroke | Ischemic Stroke | Peripheral Arterial Disease | Transient Ischemic Attack | Stable Angina Pectoris | Unstable Angina | Abdominal Aortic Aneurysm | Intracerebral Haemorrhage | Subarachnoid Haemorrhage | Coronary Heart Disease NOS | Unheralded Corronary Death | Cardiac...

United Kingdom
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Radioactive Drug (177Lu-DOTATATE) for the Treatment of Locally Advanced, Metastatic, or Unresectable Rare Endocrine Cancers

Metastatic Adrenal Gland Pheochromocytoma | Stage III Thyroid Gland Medullary Carcinoma AJCC v8 | Stage IV Thyroid Gland Medullary Carcinoma AJCC v8 | Locally Advanced Adrenal Gland Pheochromocytoma | Locally Advanced Paraganglioma | Metastatic Paraganglioma | Metastatic Parathyroid Gland Carcinoma and other conditions

United States

Clinical Trials on Benign Centrally-Located Intracranial Tumors

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