Clinical Trials on Blood Transfusion; Hemoglobinemia

Total 94085 results

Medical University of Graz
Klinikum Wels-Grieskirchen; Medical University of Vienna; Landesklinkum Wiener... and other collaborators

Recruiting

Austrian Registry on the Outcome of Monochorionic Pregnancies (MonoReg)

Twin Pregnancy With Antenatal Problem | Twin Dichorionic Diamniotic Placenta | Twin Monochorionic Monoamniotic Placenta | Twin-To-Twin Transfusion Syndrome

Austria
Second Affiliated Hospital, School of Medicine,...

Completed

Effect of Intraoperative Allogeneic Blood Transfusion on Postoperative Pulmonary Complications

Spinal Fusion | Pulmonary Complication | Transfusion

China
Centre Hospitalier Universitaire de Besancon
Centre Hospitalier Universitaire Dijon; Etablissement Français du Sang

Completed

Survival After Blood Transfusion in the French Administrative Regions of Burgundy and Franche-Comté (STeF-BFC)

Erythrocyte Transfusion for All Conditions

France
Wuhan Createrna Science and Technology Co., Ltd

Not yet recruiting

Study of Safety and Efficacy of MY008211A in in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Paroxysmal Nocturnal Hemoglobinuria (PNH)
BioCryst Pharmaceuticals

Terminated

BCX9930 for the Treatment of PNH in Subjects Not Receiving Other Complement Inhibitor Therapy (REDEEM-2)

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Malaysia, South Africa, Korea, Republic of
AKARI Therapeutics

Enrolling by invitation

Coversin in PNH in Patients With Resistance to Eculizumab Due to Complement C5 Polymorphisms (CONSENTII)

Paroxysmal Nocturnal Hemoglobinuria (PNH)

United States
Ra Pharmaceuticals, Inc.

Terminated

Extension Study of RA101495 for Patients With PNH Who Have Completed a Zilucoplan (RA101495) Clinical Study

Paroxysmal Nocturnal Hemoglobinuria (PNH)

United States, Australia, Canada, Finland, Germany, Hungary, New Zealand, United Kingdom
Assiut University

Not yet recruiting

Comparing TASH Score and Modified TBSS in Trauma Patients in Need for Massive Blood Transfusion

Massive Blood Transfusion in Trauma Patients
Radboud University Medical Center

Completed

The Pharmacokinetics and Pharmacodynamics of Eculizumab in Patients With Paroxysmal Nocturnal Hemoglobinuria (PREPARE)

Paroxysmal Nocturnal Hemoglobinuria | Eculizumab | PK-PD

Netherlands
King's College Hospital NHS Trust

Completed

Study of Global Coagulation Tests in Patients With Paroxysmal Nocturnal Haemoglobinuria

Paroxysmal Nocturnal Haemoglobinuria

United Kingdom
Second Affiliated Hospital, School of Medicine,...

Recruiting

Study on the Relationship of Arterial-venous Oxygen Difference and Postoperative Complications After Cardiac Surgery.

Cardiac Surgery | Transfusion | Patient Blood Management

China
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France; Etablissement... and other collaborators

Recruiting

Biological Parameters Changes After Autologous Blood Transfusion of Red Blood Cells (200 ml) in Healthy Volunteers. (AUTOT-SPORT)

The Focus is on the Detection of the Consequences of Autologous Blood Transfusion in Healthy Volunteers

France
Sofia Ramström

Enrolling by invitation

Transfusion of Whole Blood in Acute Bleeding (HEPEP)

Blood Transfusion | Acute Bleeding

Sweden
National Research Centre, Egypt
Cairo University

Completed

Cardiac Functions as a New Method for Evaluation of Fetal Anemia Pre and Post Intrauterine Fetal Blood Transfusion

Fetal Anemia as Antepartum Condition (Diagnosis) | Rh Incompatible Blood Transfusion Nos

Egypt
Alexion

Completed

A Study of Ravulizumab (ALXN1210) in Children and Adolescents With Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria

France, United Kingdom, Norway, Russian Federation, Netherlands, United States
Alexion
Achillion, a wholly owned subsidiary of Alexion

Completed

A Long-Term Treatment Study of ACH-0144471 in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Paroxysmal Nocturnal Hemoglobinuria

New Zealand, Korea, Republic of, Italy
Kira Pharmacenticals (US), LLC.

Completed

To Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Escalating Single and Multiple Doses of KP104

Paroxysmal Nocturnal Hemoglobinuria

Australia
Apellis Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Patients With PNH

Paroxysmal Nocturnal Hemoglobinuria

Hong Kong, Thailand, Malaysia, Singapore, Serbia, Peru, Philippines, Colombia, Mexico, Poland
AKARI Therapeutics

Terminated

rVA576 (Coversin) Long Term Safety and Efficacy Surveillance Study (CONSERVE)

Paroxysmal Nocturnal Hemoglobinuria

Poland
Alexion Pharmaceuticals

Completed

Safety and Efficacy Study of Eculizumab in Paroxysmal Nocturnal Hemoglobinuria Patients

Paroxysmal Nocturnal Hemoglobinuria
Samsung Medical Center

Completed

The Long-term Clinical Outcomes and Patterns of Transfusion in PCI Patients: Retrospective Cohort Study (TFPCI)

Percutaneous Coronary Intervention | Erythrocyte Transfusion | Revascularization

Korea, Republic of
Medical University Innsbruck

Completed

Study to Reveal if Fibrinogen Treatment Effects Blood Clotting Better Than a Platelet Transfusion (FiT2012)

Blood Clotting | Blood Platelet Transfusion

Austria, Denmark
University College Dublin
Health Research Board, Ireland; National Maternity Hospital, Ireland; Irish Blood...

Not yet recruiting

Study Comparing Platelet Transfusion Volumes in Premature Babies (PlaNeT-3)

Thrombocytopenia | Transfusion

Ireland
University Hospital Muenster

Recruiting

Effect of Electrosurgery on Blood Loss and Intraoperative Transfusions in Musculoskeletal Tumor Surgery

Blood Loss, Surgical | Transfusion Rate | Electrosurgery | Tumororthopaedics

Germany
University of Southern California

Active, not recruiting

Sequential vs. Standard Laser Treatment of Twin-twin Transfusion Syndrome

Twin Twin Transfusion Syndrome

United States
University of South Florida

Completed

Selective Laser Photocoagulation of Communicating Vessels in Twin-Twin Transfusion Syndrome (TTTS)

Twin Twin Transfusion Syndrome

United States
Jonsson Comprehensive Cancer Center

Completed

Eculizumab in Treating Patients With Paroxysmal Nocturnal Hemoglobinuria

Leukemia

United States
Janssen-Ortho Inc., Canada

Withdrawn

A Study to Determine an Effective Dose of Epoetin Alfa to Decrease the Number of Units of Blood Required to be Transfused During Hip Replacement Surgery.

Anemia | Blood Transfusion | Orthopedic Surgery
Samsung Medical Center

Completed

Bare Metal Stents and Drug Eluting Stents in Patients Who Underwent Blood Transfusion (TFPCI2)

Percutaneous Coronary Intervention | Erythrocyte Transfusion | Revascularization

Korea, Republic of
Columbia University

Completed

Renal Artery Dopplers in Twin Twin Transfusion Syndrome

Twin Twin Transfusion Syndrome

United States
AC Camargo Cancer Center

Not yet recruiting

Transfusional Trigger in Post-operative Oncologic Patients in Critical Care

Surgery | Critical Care | Oncology | Transfusion

Brazil
Brigham and Women's Hospital

Terminated

Trial of Feedback on Blood Use (TOFU)

Compliance With Restrictive RBC Transfusion Guideline

United States
Johann Wolfgang Goethe University Hospital
Wuerzburg University Hospital

Recruiting

Liberal Transfusion Strategy in Elderly Patients (LIBERAL)

Anemia | Surgery | Transfusion-dependent Anemia

Germany
BioCryst Pharmaceuticals

Active, not recruiting

A Long Term Safety Study of BCX9930 in Subjects With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Paroxysmal Nocturnal Hemoglobinuria | PNH

United Kingdom, Austria, South Africa
Alexion Pharmaceuticals

Completed

Dose-Escalation Study of ALXN1210 IV in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)

PNH

Korea, Republic of, Australia
Novartis Pharmaceuticals

Available

Managed Access Programs for LNP023, Iptacopan

Paroxysmal Nocturnal Hemoglobinuria (PNH) | C3 Glomerulopathy (C3G)
Assistance Publique - Hôpitaux de Paris
Société Française d'Hypentension Artérielle

Active, not recruiting

Monochorial-diamniotic Pregnancies Complicated With a Twin-to-twin Syndrome (STT)

Twin to Twin Transfusion Syndrome

France
Mayo Clinic
Arizona State University

Completed

Red Blood Cell Transfusion in the Ambulatory Setting: Impact on Home Functional Status

Anemia | Oncology | Ambulatory Care | Hematology | Red Blood Cell Transfusions

United States
University of Minnesota

Active, not recruiting

Clinical Impact of Red Cell Storage Age

RBC Transfusions

United States
University of Chicago

Recruiting

A Trial to Assess the Effect of Transfusion Strategies on Fatigability Levels After Hospital Discharge (EToF)

Fatigue | Anemia | Physical Function | Red Blood Cell Transfusion | Fatigability

United States
Catherine Cibulskis, MD
St. Louis University

Active, not recruiting

The Utility of MRI Scoring to Predict Neurodevelopmental Outcomes in Survivors of Twin-to-Twin Transfusion Syndrome

Fetofetal Transfusion

United States
Chang Gung Memorial Hospital

Completed

Association Between Blood Volume, the Interval From Delivery to Cord Clamping, and Number of Umbilical Cord Milking

Pregnancy Related | Placental Transfusion | Umbilical Cord Issue

Taiwan
University of Tennessee
Regional Medical Center, Regional One Health

Completed

Laser Photocoagulation in Twin to Twin Transfusion Syndrome (TTTS)

Twin to Twin Transfusion Syndrome

United States
University Hospital, Basel, Switzerland
Novartis; ProPatient foundation of the University Hospital Basel

Completed

Electronic Patient-reported Outcome Monitoring in Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria (ePRO-AA-PNH)

Aplastic Anemia | Paroxysmal Nocturnal Hemoglobinuria

Switzerland
Michael Sander

Terminated

Algorithm-Guided Transfusions in Cardiac Surgery Patients for Reduction of Drainage Blood Losses (HEART-PoC)

Chest Tube Output | Allogeneic Blood Transfusions

Germany
ADARx Pharmaceuticals, Inc.
ADARx Australia Pty Ltd

Recruiting

Safety, Tolerability, PK and PD of ADX-038 in HV and Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients (PNH)

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Australia
NovelMed Therapeutics

Not yet recruiting

Study of NM8074 in Soliris-Treated Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

PNH - Paroxysmal Nocturnal Hemoglobinuria
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Twice Daily Oral Iptacopan (LNP023) in Adult PNH Patients Who Are Naive to Complement Inhibitor Therapy (APPOINT-PNH)

Paroxysmal Nocturnal Hemoglobinuria (PNH)

China, Germany, Singapore, Korea, Republic of, Italy, United Kingdom, Malaysia, France
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Twice Daily Oral LNP023 in Adult PNH Patients With Residual Anemia Despite Anti-C5 Antibody Treatment (APPLY-PNH)

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Italy, Japan, Taiwan, Germany, France, United Kingdom, Spain, Korea, Republic of, Czechia, Brazil, Netherlands, United States
Hoffmann-La Roche
Chugai Pharmaceutical

Active, not recruiting

Study to Assess Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Crovalimab in Healthy Volunteers and Participants With Paroxysmal Nocturnal Hemoglobinuria (COMPOSER)

Paroxysmal Hemoglobinuria, Nocturnal

France, Korea, Republic of, Italy, Japan, Germany, Hungary, Netherlands

Clinical Trials on Blood Transfusion; Hemoglobinemia

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