Clinical Trials on Bone Marrow Failure Disorders

Total 9682 results

City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid... and other conditions

United States
Medical University of Warsaw

Recruiting

Possible Differences in HCC Course Depending on DAA Treatment

Liver Cirrhosis | Carcinoma, Hepatocellular | Hepatitis C, Chronic | Drug Effect | Hepatitis C Virus Infection, Response to Therapy of | Drug Side Effect

Poland
Gruppo Italiano Malattie EMatologiche dell'Adulto

Recruiting

The Incidence of Hepatitis B in Diffuse Large B-Cell Lymphoma/Chronic Lymphoid Leukemia HBsAg-positive Treated With Rituximab, Chemotherapy and Tenofovir Alafenamide (CLL1818)

Chronic Lymphoid Leukemia | Large-B-cell Diffuse Lymphoma

Italy
Andres J. M. Ferreri

Completed

Short Term Intensified Chemo-immunotherapy in HIV-positive Patients With Burkitt Lymphoma (CARMEN)

HIV | Burkitt's Lymphoma

Italy
Kami Maddocks
National Cancer Institute (NCI)

Completed

Pembrolizumab and Ibrutinib in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma

Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Mantle Cell Lymphoma | Recurrent Burkitt Lymphoma | Recurrent... and other conditions

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Deferasirox in Treating Iron Overload Caused By Blood Transfusions in Patients With Hematologic Malignancies

Primary Myelofibrosis | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Recruiting

Molecular Characterization of Viral-associated Tumors, Tumors Occurring in the Setting of HIV or Other Immune Disorders and Castleman Disease

Kaposi's Sarcoma | Human Immunodeficiency Virus | Castleman's Disease | Viral-Associated Cancer

United States
Assistance Publique - Hôpitaux de Paris
Iltoo Pharma

Completed

Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory Diseases (TRANSREG)

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Psoriasis | Systemic Sclerosis | Crohn's Disease | Ulcerative Colitis | Idiopathic Thrombocytopenic Purpura | Autoimmune Hepatitis | Wegener's Granulomatosis | Ankylosing Spondylitis | Behcet's Disease | Takayasu's Disease | Sclerosing Cholangitis | Gougerot-sj...

France
Roswell Park Cancer Institute

Withdrawn

Mechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem Cell Transplant

Primary Myelofibrosis | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma and other conditions
National Cancer Institute (NCI)

Completed

MS-275 and GM-CSF in Treating Patients With Myelodysplastic Syndrome and/or Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphocytic Leukemia

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia... and other conditions

United States
Samsung Medical Center

Completed

Factors Influencing Hepatitis B Virus Reactivation in Lymphoma Patients Treated With Rituximab

Patients With Diffuse Large B-cell Lymphoma or Follicular Lymphoma | Patients Treated With Rituximab-CHOP or Rituximab-CVP

Korea, Republic of, Malaysia, Singapore, China
Weill Medical College of Cornell University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Growth Hormone and/or Rosiglitazone for HIV-Associated Increased Abdominal Fat and Insulin Resistance

HIV Infections | Insulin Resistance | Body Weight Changes | Metabolic Syndrome X | HIV-Associated Lipodystrophy Syndrome

United States
National Institute of Allergy and Infectious Diseases...
National Cancer Institute (NCI)

Completed

A Study of Patients With AIDS Syndrome

HIV Infections | Lymphoma, Non-Hodgkin | Lymphoma, AIDS-Related | Sarcoma, Kaposi

United States
University of California, San Francisco
Massachusetts General Hospital

Recruiting

Effect of PCSK9 Inhibition on Cardiovascular Risk in Treated HIV Infection (EPIC-HIV Study) (EPIC-HIV)

Cardiovascular Diseases | HIV Infections | Dyslipidemias

United States
University of Pennsylvania
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Active, not recruiting

A Savings Intervention to Reduce Men's Engagement in HIV Risk Behaviors

Alcohol Consumption | Human Immunodeficiency Virus | Behavior | STI | Incentives

Kenya
Assiut University

Completed

Changes in Liver Fibrosis, Lipid Profile and Insulin Resistance in HCV Patients Who Received Antiviral Therapy

Chronic Hepatitis c

Egypt
Icahn School of Medicine at Mount Sinai

Completed

Eliminating Hepatitis C Virus

Hepatitis C | HIV | Type2 Diabetes

United States
AbbVie

Completed

Quality of Life Measurement in Treatment Naïve Patients With Hepatitis C Virus (HCV) Genotype 1 (GT1) Suffering From Fatigue and Receiving Ombitasvir, Paritaprevir, and Ritonavir and Dasabuvir (Viekirax®/Exviera®) (HEMATITE)

Chronic Hepatitis C Virus (HCV)

Switzerland
National Institute of Allergy and Infectious Diseases...

Completed

Nerve Damage in Patients With HIV Infection Who Have Been Treated With Anti-HIV Drugs

HIV Infections | Peripheral Nervous System Disease

United States
Bristol-Myers Squibb

Completed

Study of Reyataz in HIV-infected Patients With Lipodystrophy Syndrome

HIV-Associated Lipodystrophy Syndrome

Spain, Italy, United States, Canada, France, Mexico, United Kingdom, Poland, Germany
National Institute of Diabetes and Digestive and...

Completed

AIDS Wasting in Women: Anabolic Effects of Testosterone

AIDS Wasting Syndrome

United States
Celgene Corporation

Completed

Compassionate Use Study of Two Dose Levels of Thalidomide in Adults With HIV Wasting Syndrome

HIV Infections | HIV Wasting Syndrome

United States
SWOG Cancer Research Network
National Cancer Institute (NCI); Genentech, Inc.

Recruiting

Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

Diffuse Large B-Cell Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Grade 3b Follicular Lymphoma | Transformed Follic Lymph to Diff Large B-Cell Lymphoma | Transformed Marg Zone Lymph to Diff...

United States
University of Novi Sad
Merck Sharp & Dohme LLC

Recruiting

Neuroinflammation and Neurodegeneration in HIV-positive Subjects Switched and Initially Treated With INSTI

Metabolic Syndrome | Aging | HIV I Infection | HIV Associated Lipodystrophy

Serbia
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Genetically Modified Peripheral Blood Stem Cell Transplant in Treating Patients With HIV-Associated Non-Hodgkin or Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

A Pilot Study to Evaluate the Co-Infusion of Ex Vivo Expanded Cord Blood Cells With an Unmanipulated Cord Blood Unit in Patients Undergoing Cord Blood Transplant for Hematologic Malignancies

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Immunoblastic Large Cell Lymphoma and other conditions

United States
University of California, San Francisco
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Syracuse University and other collaborators

Completed

Mobile Technology to Extend Clinic-based Counseling for HIV+s in Uganda (EXTEND)

HIV/AIDS | Alcohol Use, Unspecified

Uganda
National Institute of Allergy and Infectious Diseases...

Completed

A Study to Evaluate the Effect of Nandrolone Decanoate in Women With HIV-Associated Weight Loss

HIV Infections | HIV Wasting Syndrome

United States, Puerto Rico
Harvard School of Public Health (HSPH)

Completed

Botswana Pediatric Respiratory Disease and Bloodstream Infection Study

HIV Infections | Respiratory Tract Diseases | Sepsis

Botswana
Kirby Institute
Bristol-Myers Squibb; GlaxoSmithKline; Merck Sharp & Dohme LLC; Gilead Sciences; Hoffmann-La... and other collaborators

Terminated

Facial Lipoatrophy Trial: Immediate Versus Deferred Injections of Poly-L-Lactic Acid for HIV Facial Lipoatrophy

HIV Infections | HIV-Associated Lipodystrophy

Australia
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Roxane Laboratories

Completed

A Phase I/II Study to Evaluate Single Agent and Combination Therapy With Megestrol Acetate and Dronabinol for the Treatment of HIV-Wasting Syndrome

HIV Infections | Cachexia | HIV Wasting Syndrome

United States
French National Agency for Research on AIDS and...

Terminated

Evaluation of the Occurrence of Lipoatrophy in HIV-1 Infected Naive Patients

HIV Infections | HIV-Associated Lipodystrophy Syndrome

France
Celgene Corporation

Completed

A Phase II, Parallel Group, Randomized, Placebo-Controlled Study of the Safety and Efficacy of Thalidomide in Reducing Weight Loss in Adults With HIV Wasting Syndrome

HIV Infections | HIV Wasting Syndrome

United States
National Cancer Institute (NCI)

Completed

7-Hydroxystaurosporine and Perifosine in Treating Patients With Relapsed or Refractory Acute Leukemia, Chronic Myelogenous Leukemia or High Risk Myelodysplastic Syndromes

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute... and other conditions

United States
National Cancer Institute (NCI)

Completed

Lenalidomide After Donor Bone Marrow Transplant in Treating Patients With High-Risk Hematologic Cancers

Recurrent Adult Burkitt Lymphoma | Recurrent Adult Lymphoblastic Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic Marginal Zone Lymphoma | Waldenstrom... and other conditions

United States
National Institute of Allergy and Infectious Diseases...

Terminated

2-5 Intermittent Caloric Restriction in HIV (2-5toWIN)

Metabolic Syndrome | Human Immunodeficiency Virus

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Study of Megestrol Acetate Alone or in Combination With Testosterone Enanthate Drug in the Treatment of HIV-Associated Weight Loss

HIV Infections | HIV Wasting Syndrome

United States
Marie-Josée Brouillette
Fonds de la Recherche en Santé du Québec; CIHR Canadian HIV Trials Network

Terminated

COMO: Cognition Study With HIV+ Patients (CTNPT 015) (COMO)

HIV - Human Immunodeficiency Virus | Cognitive Symptoms

Canada
ViiV Healthcare
GlaxoSmithKline

Completed

An Study to Investigate the Recovery, Excretion, and Pharmacokinetics of 14C-GSK1265744 Administered as a Single Oral Dose and a Study to Describe the Pharmacokinetics of a Supratherapeutic Dose of GSK1265744 in Healthy Adult Subjects

HIV-associated Lipodystrophy Syndrome

United States
French National Agency for Research on AIDS and...

Terminated

Study Evaluating the Impact on Fat Distribution of Nucleoside Reverse Transcriptase Inhibitor (NRTI)-Sparing Regimens in Antiretroviral Experienced Patients With Lipoatrophy

HIV Infections | HIV Lipodystrophy Syndrome

France
Amgen

Completed

A Randomized, Controlled, Multicenter Trial of Filgrastim (Recombinant-Methionyl Human Granulocyte Colony Stimulating Factor; G-CSF) for the Prevention of Grade 4 Neutropenia in Patients With HIV Infection.

HIV Infections | Cytopenias

United States, Canada
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Massage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Cancer

Unspecified Childhood Solid Tumor, Protocol Specific | Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Juvenile Myelomonocytic Leukemia | Burkitt Lymphoma | Secondary... and other conditions

United States
National Cancer Institute (NCI)

Terminated

Tanespimycin and Bortezomib in Treating Patients With Advanced Solid Tumors or Lymphomas

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Allegheny Singer Research Institute (also known...
ElectroCore INC

Terminated

Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory Symptoms (SAVIORII)

Respiratory Failure | COVID | Corona Virus Infection | Respiratory Distress Syndrome, Adult | SARS (Severe Acute Respiratory Syndrome) | ARDS, Human

United States
Hôpital Louis Mourier

Completed

Extended Prone Position Duration COVID-19-related ARDS: a Retrospective Study

Pressure Ulcer | Hypoxemic Respiratory Failure | COVID-19 Acute Respiratory Distress Syndrome | Respiratory Distress Syndrome, Acute

France
VA Office of Research and Development
US Department of Veterans Affairs

Completed

Evaluation of Implementation of a National Point-of-Care Ultrasound Training Program

Heart Failure | Pneumonia | Cellulitis | Urinary Retention | Deep Venous Thrombosis | Hydronephrosis | Pleural Effusion | Abdominal Aortic Aneurysm | Acute Cholecystitis | Other Acute Illnesses Presenting to the Hospital | Peritoneal Free Fluid

United States
Changi General Hospital
Singapore General Hospital

Recruiting

Outcome of Patients With Primary Aldosteronism (PA_Outcome)

Primary Aldosteronism | Hypokalemia | Chronic Renal Disease | Cardiovascular Morbidity | Mineralocorticoid Excess | Adrenalectomy; Status | Primary Aldosteronism Due to Aldosterone Producing Adenoma | Primary Aldosteronism Due to Adrenal Hyperplasia (Bilateral) | Mineralocorticoid Antagonists [Aldosterone...

Singapore
Cellectar Biosciences, Inc.

Active, not recruiting

Dose Escalation Study of CLR 131 in Children, Adolescents, and Young Adults With Relapsed or Refractory Malignant Tumors Including But Not Limited to Neuroblastoma, Rhabdomyosarcoma, Ewings Sarcoma, and Osteosarcoma (CLOVER-2)

Osteosarcoma | Ewing Sarcoma | Neuroblastoma | Rhabdomyosarcoma | Pediatric Brain Tumor | DIPG | Pediatric Solid Tumor | Pediatric Lymphoma

United States, Australia, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia

Acute Myeloid Leukemia | Recurrent Adult Acute Myeloid Leukemia | Fungal Infection | Neutropenia | Secondary Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia in Remission | Childhood Acute Myeloid Leukemia in Remission | Recurrent Childhood Acute Myeloid... and other conditions

United States, Canada, Puerto Rico
University of Washington

Active, not recruiting

Docetaxel, Carboplatin, and Rucaparib Camsylate in Treating Patients With Metastatic Castration Resistant Prostate Cancer With Homologous Recombination DNA Repair Deficiency

BRCA1 Gene Mutation | BRCA2 Gene Mutation | Castration-Resistant Prostate Carcinoma | Homologous Recombination Deficiency | PSA Progression | Stage IV Prostate Adenocarcinoma AJCC v7 | Castration Levels of Testosterone | ATM Gene Mutation | Prostate Carcinoma Metastatic in the Bone | PSA Level Greater...

United States

Clinical Trials on Bone Marrow Failure Disorders

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