Clinical Trials on Brain Diseases in Portugal

Total 2768 results

PTC Therapeutics

Recruiting

A Long-Term Safety Study of PTC923 in Participants With Phenylketonuria

Phenylketonuria

United States, Germany, Spain, Australia, Brazil, United Kingdom, Denmark, Mexico, Portugal, Turkey, Canada, Georgia, Italy, Netherlands, Japan
Medtronic Bakken Research Center

Completed

PORTuguese Research on Telemonitoring With CareLink® (PORTLink) (PORTLink)

Arrhythmia

Portugal
Genzyme, a Sanofi Company

Completed

A Study of Eliglustat Tartrate (Genz-112638) in Patients With Gaucher Disease to Evaluate Once Daily Versus Twice Daily Dosing (EDGE)

Gaucher Disease

United States, Sweden, India, Netherlands, Austria, Japan, China, Serbia, France, Croatia, Australia, Portugal, Canada, Brazil, Greece, Romania, Russian Federation
Allergan

Completed

An Exploratory Study to Evaluate the Safety of Brimonidine Intravitreal Implant in Patients With Retinitis Pigmentosa

Retinitis Pigmentosa

France, United States, Germany, Portugal
University of Trás-os-Montes and Alto Douro

Unknown

Stress Urinary Incontinence in Elite Athletes

Pelvic Floor Disorders

Portugal
Novartis Pharmaceuticals

Recruiting

Dose Finding Study of [177Lu]Lu-NeoB in Newly Diagnosed Glioblastoma and in Recurrent Glioblastoma

Newly Diagnosed and Recurrent Glioblastoma

Spain, Israel, Portugal, France
Association for Innovation and Biomedical Research...
European Vision Institute Clinical Research Network

Completed

Randomized, Double-masked, Sham-controlled Phase 4 Study, Efficacy, Safety, and Tolerability of Intravitreal Aflibercept Monotherapy Compared to Aflibercept With Adjunctive Photodynamic Therapy in Patients With Polypoidal Choroidal Vasculopathy (ATLANTIC)

Polypoidal Choroidal Vasculopathy

Portugal, Spain
Centro Hospitalar Lisboa Ocidental
Abbott Medical Devices; Cardiovascular Research Foundation, New York

Unknown

Performance of a New REsting Pressure Index During Invasive Angiography Compared To Adenosine Hyperemic FFR (PREDICT)

Coronary Artery Disease | Fractional Flow Reserve, Myocardial

United States, France, Italy, Portugal
Universidad de León

Completed

Custom Foot Orthoses & Venous Status

Venous Stasis | Foot | Foot Orthoses | Photoplethysmography

Portugal
Société Internationale d'Urologie

Active, not recruiting

Benign Prostatic Hyperplasia (BPH) Mobile Application Pilot Study

Lower Urinary Tract Symptoms | Prostatic Hyperplasia

Turkey, Portugal, Italy, Greece, Spain
Norgine
Xolomon Tree S.L.

Completed

Real Word Evidence With 1L Polyethylene Glycol (PEG)+ Ascorbic Acid in Iberia

Colon Cancer | Colon Disease | Colon Cleansing

Spain, Portugal
UMC Utrecht
Zimmer Biomet

Enrolling by invitation

Diagnosis and Bacterial Identification of Periprosthetic Joint Infection With Microbial-ID (MID)

Periprosthetic Joint Infection | PJI

Netherlands, Spain, Germany, Portugal, Slovenia, Switzerland
Pfizer

Terminated

A Study to Evaluate the Efficacy and Safety of CP-101,606 in Subjects With an Acute Stroke

Stroke

United States, Italy, Spain, Singapore, Germany, Estonia, Portugal, Hungary
Swedish Orphan Biovitrum

Completed

Long Term Safety Study of Orfadin Treatment in HT-1 Patients in Standard Clinical Care (OPAL)

Hereditary Tyrosinemia, Type I

Belgium, Denmark, France, Germany, Austria, Czechia, Finland, Hungary, Ireland, Italy, Netherlands, Norway, Poland, Portugal, Spain, Sweden, United Kingdom
Amsterdam UMC, location VUmc
University of Bergen; University of Oxford; Centre Hospitalier Universitaire... and other collaborators

Recruiting

Developing Trustworthy Artificial Intelligence (AI)-Driven Tools to Predict Vascular Disease Risk and Progression (VASCULAIDRETRO)

Peripheral Arterial Disease | Aneurysm Abdominal

Netherlands, United Kingdom, Finland, Germany, Portugal, Serbia
Genzyme, a Sanofi Company

Completed

Efficacy, Safety, Pharmacodynamic, and Pharmacokinetics Study of Olipudase Alfa in Patients With Acid Sphingomyelinase Deficiency (ASCEND)

Sphingomyelin Lipidosis

United States, Argentina, Australia, Belgium, Brazil, Bulgaria, Chile, France, Germany, Italy, Japan, Netherlands, Portugal, Spain, Tunisia, Turkey, United Kingdom
Neovii Biotech
Eurotrials Brasil Consultores Cientificos Ltda; Recerca Clínica S.L.; PsyConsult

Terminated

Efficacy and Safety of ATG-Fresenius Following a Renal Transplantation, Without Corticosteroids (IBERICA)

Renal Transplant Rejection

Spain, Portugal
Novartis Pharmaceuticals

Active, not recruiting

Observational Study to Evaluate Fluid Resolution and Effectiveness of Brolucizumab for nAMD in Portugal (BLUESKY-PT)

Neovascular Age-related Macular Degeneration (nAMD)

Portugal
Grupo de Investigacao do Cancro Digestivo

Unknown

XELOX Plus Cetuximab as First-Line Therapy in Patients With Metastatic Colorectal Cancer

Colorectal Carcinoma

Portugal
Nektar Therapeutics

Completed

A Study of Etirinotecan Pegol (NKTR-102) Versus Treatment of Physician's Choice (TPC) in Patients With Metastatic Breast Cancer Who Have Stable Brain Metastases and Have Been Previously Treated With an Anthracycline, a Taxane, and Capecitabine (ATTAIN)

Breast Cancer | Metastasis

United States, Australia, Belgium, Canada, France, Israel, Italy, Portugal, Spain, United Kingdom
Celgene

Completed

Safety Study of Lenalidomide/Dexamethasone to Treat Patients With Relapsed or Refractory Multiple Myeloma (PrObe-L)

Multiple Myeloma

Portugal
PTC Therapeutics

Completed

A Study of PTC923 in Participants With Phenylketonuria

Phenylketonuria

Spain, United States, Australia, Germany, United Kingdom, Brazil, Denmark, Canada, France, Georgia, Italy, Mexico, Netherlands, Portugal, Turkey
Novo Nordisk A/S

Completed

Changing Diabetes® World Tour

Diabetes Mellitus, Type 2 | Diabetes | Diabetes Mellitus, Type 1

United Arab Emirates, Saudi Arabia, Portugal
Alnylam Pharmaceuticals

Completed

Trial to Evaluate Safety and Tolerability of ALN-TTR01 in Transthyretin (TTR) Amyloidosis

Transthyretin Mediated Amyloidosis (ATTR)

United Kingdom, France, Portugal, Sweden
Bial - Portela C S.A.

Active, not recruiting

eArly levoDopa With Opicapone in Parkinson's paTients wIth motOr fluctuatioNs. (ADOPTION)

Parkinson Disease

Spain, Italy, Portugal, Germany, United Kingdom
University of Alberta

Recruiting

Cytolytic Vaginosis Multicentre Registry

Cytolytic Vaginosis

Brazil, Canada, Portugal
Hospital Clinic of Barcelona
Fundacion Clinic per a la Recerca Biomedica; Brighton and Sussex University... and other collaborators

Unknown

Validation Study of mHealth Technology in HIV to Improve Empowerment and Healthcare Utilisation: Research and Innovation to Generate Evidence for Personalised Care (EmERGE) (EMERGE)

HIV Infections

Spain, Belgium, Croatia, Portugal, United Kingdom
UMC Utrecht
FPC De Kijvelanden, Poortugaal

Terminated

Efficacy of a Triptan in the Treatment of Hostility and Aggression Among Convicts With a Psychiatric Treatment Order

Psychotic Disorders | Antisocial Personality Disorder | Intermittent Explosive Disorder | Impulse Regulation Disorder

Netherlands
BioMarin Pharmaceutical

Completed

Observational Study on the Long Term Safety of Kuvan® Treatment in Patients With Hyperphenylalaninemia (HPA) Due to Phenylketonuria (PKU) or BH4 Deficiency (KAMPER)

Hyperphenylalaninemia (HPA) Due to Phenylketonuria (PKU) or Tetrahydrobiopterin (BH4) Deficiency

Sweden, France, Italy, Spain, Germany, Netherlands, Austria, Slovakia, Portugal
The Netherlands Cancer Institute
Institut Curie

Terminated

Pre- Versus Postoperative Accelerated Partial Breast Irradiation (PAPBI-2)

Breast Cancer | Neoplasms, Breast | Cancer of the Breast

France, Netherlands, Portugal, Spain
University Hospital Inselspital, Berne

Terminated

Combined Transcatheter Aortic Valve Implantation and Percutaneous Closure of the Left Atrial Appendage (TAVI-LAAC)

Aortic Valve Disorder

Switzerland, Italy, Germany, Portugal
AstraZeneca
Daiichi Sankyo

Completed

A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer (DESTINY-B12)

Breast Cancer

Denmark, Finland, Italy, Norway, Spain, Sweden, Poland, United States, Canada, Germany, Japan, Netherlands, Portugal, Switzerland, Australia, United Kingdom, Belgium, Ireland
Bial - Portela C S.A.

Completed

Safety and Efficacy of Eslicarbazepine Acetate as Adjunctive Therapy for Partial Seizures in Elderly Patients

Epilepsy

Spain, Bulgaria, Austria, Croatia, Czechia, France, Germany, Poland, Portugal, Romania
Ipsen

Completed

Lanreotide Autogel 120 mg at Extended Dosing Intervals (>4 Weeks) in Acromegalic Subjects (SOMACROL)

Acromegaly

Spain, Portugal
Hoffmann-La Roche

Completed

A Study of Tocilizumab Plus Non-biological DMARD in Patients With Moderate to Severe Rheumatoid Arthritis and an Inadequate Response to Non-biological DMARDs

Rheumatoid Arthritis

Portugal
Hannover Medical School

Not yet recruiting

Plasma Exchange for Amanita Toxin-induced Acute Liver Failure (Amanita-Pex)

Acute Liver Failure

Spain, Germany, Mexico, Italy, Portugal
Memorial Sloan Kettering Cancer Center
University of Pisa; University of California, San Francisco; The Champalimaud...

Active, not recruiting

Randomized Study Comparing Two Dosing Schedules for Hypofractionated Image-Guided Radiation Therapy

Melanoma | Sarcoma | Ovarian Cancer | Bone | Soft Tissue | Lymph Nodes | CNS-Spinal CD/MEMBR, NOS

United States, Italy, Portugal
Rsocialform - Geriatria, Lda

Completed

Comparison Study of the Different Abbreviated Versions of the Geriatric Depression Scale

Depressive Disorder | Depression | Neurocognitive Disorders | Dementia

Portugal
Fundacao Champalimaud
European Commission; Cankado GmbH; Bocconi University; INESC TEC - Institute for... and other collaborators

Recruiting

Comparing Decision on Aesthetics After Breast Cancer Locoregional Treatment. (CINDERELLA)

Breast Cancer

Germany, Israel, Italy, Portugal, Poland
Universidade do Porto

Completed

Does Midazolam Affect Postoperative Pain?

Pain, Postoperative

Portugal
BioProtect

Active, not recruiting

Post Marketing Clinical Follow Up of the BioProtect Balloon Implant System (CLP-10441)

Prostate Cancer

Israel, Netherlands, Portugal, Ireland, Poland
Boehringer Ingelheim

Completed

A Study to Test Whether Nintedanib Influences the Components of Birth-control Pills in Women With Systemic Sclerosis Associated Interstitial Lung Disease (SSc-ILD)

Scleroderma, Systemic

Spain, Germany, France, Belgium, Portugal, Netherlands
Euresist Network GEIE
Heinrich-Heine University, Duesseldorf; Centro Hospitalar Lisboa Ocidental; ASST... and other collaborators

Recruiting

Health Care Workers Cohort Study in the EuCARE Project (EuCARE-HCW)

COVID-19

Germany, Italy, Lithuania, Mexico, Portugal, Vietnam
Insel Gruppe AG, University Hospital Bern

Completed

Early Versus Late Initiation of Direct Oral Anticoagulants in Post-ischaemic Stroke Patients With Atrial fibrillatioN (ELAN): an International, Multicentre, Randomised-controlled, Two-arm, Assessor-blinded Trial (ELAN)

Ischaemic Stroke

Belgium, Ireland, Israel, Germany, India, United Kingdom, Austria, Switzerland, Finland, Norway, Italy, Portugal, Slovakia, Japan, Greece
University Hospital, Basel, Switzerland
Boehringer Ingelheim

Recruiting

International Rare And Severe Psoriasis Expert Network (IRASPEN)

Pustular Psoriasis (PP)

Germany, Italy, Singapore, Switzerland, Portugal, Turkey
European Organisation for Research and Treatment...

Completed

Glufosfamide in Treating Patients With Recurrent Glioblastoma Multiforme

Brain and Central Nervous System Tumors

France, Switzerland, Italy, Israel, Netherlands, Portugal, Austria, Greece
Bayer
Regeneron Pharmaceuticals

Completed

Evaluation of Changes in Visual Acuity in Patients With Diabetic Macular Edema (DME) Starting Treatment With an Approved Anti-VEGF Therapy (POLARIS)

Macular Degeneration | Macular Edema | Ophthalmology

Slovakia, France, Germany, Spain, Russian Federation, United Kingdom, Portugal, Greece
Sino Medical Sciences Technology Inc.

Completed

First-in-man Trial Examining the Safety and Efficacy of BuMA Supreme and Resolute Integrity in Patients With de Novo Coronary Artery Stenosis

Coronary Artery Disease

Netherlands, Belgium, Spain, Portugal
Boehringer Ingelheim

Completed

A Clinical Trial Comparing Efficacy and Safety of Dabigatran Etexilate With Warfarin in Patients With Cerebral Venous and Dural Sinus Thrombosis (RE-SPECT CVT)

Thromboembolism

Spain, Germany, India, Italy, Netherlands, Portugal, France, Poland, Russian Federation
Genzyme, a Sanofi Company

Completed

A Retrospective Observational Study Comparing Two Different Treatment Options in Thyroid Cancer Patients With T4 Tumours

Thyroid Cancer

Spain, Germany, Italy, Portugal

Clinical Trials on Brain Diseases in Portugal

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CROs in Macedonia

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