Clinical Trials on Brain Stem Gliomas in United States

Total 14159 results

Novartis Pharmaceuticals

Completed

Efficacy and Safety Evaluation of Osilodrostat in Cushing's Disease (LINC-4)

Cushing's Disease

United States, China, Canada, Belgium, Thailand, Spain, Turkey, Brazil, Portugal, Russian Federation, Poland, Greece, Costa Rica, Switzerland
Cognito Therapeutics, Inc.

Enrolling by invitation

Extension to a Pivotal Study of Sensory Stimulation in Alzheimer's Disease (OLE Hope Study, CA-0015)

Cognitive Impairment | Alzheimer Disease | Mild Cognitive Impairment | Dementia Alzheimers | Dementia of Alzheimer Type | AD | Dementia, Mild | Dementia Moderate

United States
Neurocrine Biosciences

Completed

Safety, Tolerability, and Efficacy of NBI-98854 for the Treatment of Pediatric Subjects With Tourette Syndrome

Tourette Syndrome

United States, Puerto Rico
UCB Pharma

Completed

An Open-Label Extension Trial to Assess the Safety of Long-Term Treatment of Rotigotine in Advanced-Stage Parkinson's Disease

Advanced Stage Parkinson's Disease

France, Italy, Poland, United Kingdom, Spain, Germany, South Africa, New Zealand, Czech Republic, Hungary, Australia, Austria, Israel, Sweden, Norway, Croatia, Finland
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A Clinical Study in Participants With Huntington's Disease (HD) to Assess Efficacy and Safety of Three Oral Doses of Laquinimod (LEGATO-HD)

Huntington's Disease

United States, Canada, Czechia, Germany, Italy, Netherlands, Portugal, Russian Federation, Spain, United Kingdom
Karuna Therapeutics

Recruiting

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)

Psychosis Associated With Alzheimer's Disease

Korea, Republic of, United States, Belgium, Canada, Chile, China, Greece, Hungary, Mexico, Peru, Poland, Switzerland, Turkey, United Kingdom
Imperial College London
Sanofi; Axtria, Inc.

Recruiting

OptimiZation Of Lipid Lowering Therapies Using a Decision Support System In Patients With Acute Coronary Syndrome. (ZODIAC)

Myocardial Infarction | Ischemic Stroke | Acute Coronary Syndrome

United Kingdom
Teva Branded Pharmaceutical Products R&D, Inc.
Nuvelution TS Pharma, Inc.

Completed

Alternatives for Reducing Tics in Tourette Syndrome (TS): A Study of TEV-50717 (Deutetrabenazine) for the Treatment of Tourette Syndrome in Children and Adolescents (ARTISTS1)

Tourette Syndrome

United States, Canada, Denmark, Russian Federation, Serbia, Spain
Bayer
Janssen Research & Development, LLC; Population Health Research Institute

Terminated

Rivaroxaban Versus Aspirin in Secondary Prevention of Stroke and Prevention of Systemic Embolism in Patients With Recent Embolic Stroke of Undetermined Source (ESUS) (NAVIGATE ESUS)

Stroke

Denmark, France, Spain, China, United States, Switzerland, Germany, Greece, Korea, Republic of, Portugal, Japan, Israel, Canada, Australia, Turkey, Russian Federation, Sweden, Austria, Czechia, Poland, United Kingdom, Belgium, Brazil, Hungar... and more
Takeda
Ovid Therapeutics Inc.

Completed

A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-935 (OV935) as an Adjunctive Therapy in Pediatric Participants With Developmental and/or Epileptic Encephalopathies (ELEKTRA)

Epilepsy | Dravet Syndrome | Lennox-Gastaut Syndrome

United States, Canada, Israel, Poland, Spain, Australia, China, Portugal
Children's Cancer and Leukaemia Group

Completed

High-Dose Methotrexate in Treating Young Patients With Solid Tumors

Sarcoma | Unspecified Childhood Solid Tumor, Protocol Specific | Brain and Central Nervous System Tumors

United Kingdom, Ireland
Biohaven Pharmaceuticals, Inc.

Completed

Study of BHV-3241 in Participants With Multiple System Atrophy (M-STAR)

Multiple System Atrophy

United States, Germany, Austria, France, Italy, United Kingdom
University College, London
University of Oxford; Newcastle University; University of Cambridge; University... and other collaborators

Recruiting

PROgressive Supranuclear Palsy CorTico-Basal Syndrome Multiple System Atrophy Longitudinal Study UK (PROSPECT-M)

Corticobasal Degeneration | Multiple System Atrophy (MSA) | Progressive Supranuclear Palsy (PSP)

United Kingdom
NYU Langone Health

Recruiting

Natural History Study of Synucleinopathies

Parkinson Disease | Multiple System Atrophy | Neurogenic Orthostatic Hypotension | REM Sleep Behavior Disorder | Pure Autonomic Failure | Dementia With Lewy Bodies | Patients With Synucleinopathies | Shy-Drager Disease

Korea, Republic of, United States, Argentina, Spain
Nestlé
Nestec Ltd.; Regulatory and Clinical Research Institute Inc; Cytel Inc.

Terminated

Videofluoroscopic Swallowing Study (VFSS) (PORSCHE)

Stroke | Multiple Sclerosis | Parkinson Disease | Dementia | Alzheimer Disease | Oropharyngeal Dysphagia

United States, Finland
National Institute of Allergy and Infectious Diseases...

Completed

A Study to Evaluate the Use of Cidofovir (an Experimental Drug) for the Treatment of Progressive Multifocal Leukoencephalopathy (PML) in AIDS Patients

HIV Infections | Leukoencephalopathy, Progressive Multifocal

United States
University of Oxford
Medical Research Council

Completed

Deep Brain Stimulation for Autonomic and Gait Symptoms in Multiple System Atrophy (STAG-MSA)

Multiple System Atrophy | Gait Disorders, Neurologic | Bladder, Neurogenic | Autonomic Failure | Postural Hypotension

United Kingdom
UCB Pharma

Completed

An Open-Label Extension Trial to Assess the Safety of Long-Term Treatment of Rotigotine in Early-Stage Parkinson's Disease

Early Stage Parkinson's Disease

Poland, United Kingdom, Germany, Spain, Switzerland, Belgium, South Africa, New Zealand, Czech Republic, Austria, Hungary, Australia, Italy, Israel, Sweden, Norway, Croatia, Netherlands, Finland, France
ACADIA Pharmaceuticals Inc.

Completed

A Study of the Safety and Efficacy of Pimavanserin (ACP-103) in Patients With Parkinson's Disease Psychosis

Parkinson's Disease Psychosis

France, United States, Bulgaria, Russian Federation, United Kingdom, Ukraine, India
Merck KGaA, Darmstadt, Germany

Completed

An Open-label Phase 4 Study to Explore Immunogenicity of the Liquid Formulation of Saizen® in Subjects With Adult Growth Hormone Deficiency (AGHD)

Adult Growth Hormone Deficiency

United Kingdom, Germany, Australia, Sweden
Novartis Pharmaceuticals

Completed

Safety and Efficacy of LCI699 for the Treatment of Patients With Cushing's Disease

Cushings Disease

United States, Canada, Italy, India, Japan, Austria, Netherlands, Spain, Korea, Republic of, Germany, Thailand, France, Bulgaria, Turkey, Colombia, China, Argentina, Russian Federation, United Kingdom
ACADIA Pharmaceuticals Inc.

Completed

A Study of Safety and Efficacy of Pimavanserin (ACP-103) in Patients With Parkinson's Disease Psychosis

Parkinson's Disease Psychosis

Spain, United States, Belgium, Austria, Serbia, Poland, Portugal, Italy, Sweden
Biogen

Terminated

Study of BIIB092 in Participants With Progressive Supranuclear Palsy (PASSPORT)

Supranuclear Palsy, Progressive

United States, France, Italy, Korea, Republic of, Russian Federation, Spain, United Kingdom, Austria, Canada, Germany, Japan, Australia, Greece
Prilenia

Active, not recruiting

PRidopidine's Outcome On Function in Huntington Disease, PROOF- HD

Huntington Disease

United States, Austria, Canada, Czechia, France, Germany, Italy, Netherlands, Poland, Spain, United Kingdom
University of Pennsylvania

Recruiting

Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis (LoDoNaVasc)

Giant Cell Arteritis | Microscopic Polyangiitis | Polyarteritis Nodosa | Granulomatosis With Polyangiitis | Takayasu Arteritis | Eosinophilic Granulomatosis With Polyangiitis (EGPA) | Churg-Strauss Syndrome (CSS)

United States, Canada
Satsuma Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Safety of STS101 in the Acute Treatment of Migraine (ASCEND)

Migraine | Migraine Without Aura | Migraine With Aura

United States
Quince Therapeutics S.p.A.

Completed

Intra-Erythrocyte Dexamethasone Sodium Phosphate in Ataxia Telangiectasia Patients (ATTeST)

Genetic Syndrome | Nervous System Disease

India, United States, Australia, Germany, Italy, Norway, Poland, Spain, Tunisia, United Kingdom, Israel, Belgium
Sage Therapeutics

Recruiting

A Study to Evaluate the Effect of SAGE-718 on Cognitive Function in Participants With Huntington's Disease (HD)

Huntington's Disease

United States, Australia, Canada, United Kingdom
Prilenia

Terminated

A Study Evaluating if Pridopidine is Safe, Efficacious, and Tolerable in Patients With Huntington's Disease (Open PRIDE-HD)

Huntington's Disease

United States, Australia, Austria, Canada, France, Germany, Italy, Netherlands, Poland, Russian Federation, United Kingdom
Teva Branded Pharmaceutical Products R&D, Inc.
H. Lundbeck A/S

Completed

Clinical Trial to Assess Efficacy, Safety, and Tolerability of Rasagiline Mesylate 1 mg in Patients With Multiple System Atrophy of the Parkinsonian Subtype (MSA-P)

Multiple System Atrophy

United States, Austria, Canada, France, Germany, Hungary, Israel, Italy, Netherlands, Portugal, Spain, United Kingdom
Balt USA
AXIOM Real Time Metrics; Embo-Flüssigkeiten A.G.; Balt Extrusion

Active, not recruiting

The SQUID Trial for the Embolization of the Middle Meningeal Artery for Treatment of Chronic Subdural Hematoma (STEM) (STEM)

Subdural Hematoma, Chronic

United States, France, Germany, Spain
AbbVie

Terminated

An Extension Study of ABBV-8E12 in Progressive Supranuclear Palsy (PSP)

Progressive Supranuclear Palsy (PSP)

United States, Australia, Canada, Italy, Japan
Eisai Inc.
National Institute on Aging (NIA); Biogen; Alzheimer's Clinical Trials Consortium

Recruiting

AHEAD 3-45 Study: A Study to Evaluate Efficacy and Safety of Treatment With Lecanemab in Participants With Preclinical Alzheimer's Disease and Elevated Amyloid and Also in Participants With Early Preclinical Alzheimer's Disease and Intermediate Amyloid

Preclinical Alzheimer's Disease | Early Preclinical Alzheimer's Disease

United States, Singapore, Canada, Spain, Australia, Japan, United Kingdom, Sweden, Netherlands
Takeda

Active, not recruiting

A Study of Soticlestat in Adults and Children With Rare Epilepsies (Endymion 1)

Epilepsy | Dravet Syndrome (DS) | Lennox-Gastaut Syndrome (LGS)

United States, Canada, Australia, China, Israel, Poland, Spain, Portugal
Karuna Therapeutics

Enrolling by invitation

Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

Psychosis Associated With Alzheimer's Disease

Spain, United States, Belgium, Bulgaria, Canada, Chile, China, Croatia, Czechia, France, Germany, Greece, Hungary, Italy, Korea, Republic of, Mexico, Peru, Poland, Serbia, Slovakia, Turkey, United Kingdom
Boehringer Ingelheim

Completed

Impulse Control Disorders in Parkinson's Patients Treated With Pramipexole and Other Agents (DOMINION Study)

Parkinson Disease

United States, Canada
Novartis Pharmaceuticals

Completed

Effects of Carbidopa/Levodopa/Entacapone on Motor Function and Quality of Life in Patients With Parkinson's Disease

Parkinson's Disease With End of Dose Wearing Off

United States, Puerto Rico
Sanguine Biosciences

Completed

At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions

Depression | Melanoma | Epilepsy | Lymphoma | Multiple Sclerosis | Kidney Cancer | Cervical Cancer | Diabetes Mellitus | Leukemia | Breast Cancer | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Parkinson's Disease | Systemic Lupus Erythematosus | Multiple Myeloma | Hepatitis B | Insomnia | Colorectal Cancer | HIV/AID... and other conditions

United States
Takeda

Completed

Efficacy and Safety of Ramelteon in Subjects With Mild to Moderate Alzheimer's Disease

Chronic Insomnia

United States
Abbott Medical Devices

Completed

PREMIUM Migraine Trial

Patent Foramen Ovale | Migraine Headaches

United States
Debiopharm International SA

Active, not recruiting

A Study to Assess the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Debio 4126 in Participants With Acromegaly or Functioning Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs) (OXTEND-01)

Acromegaly | GEP-NET

United Kingdom, France, Spain, Italy, Poland, Denmark, Germany, Israel
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Eletriptan Provides Consistent Migraine Relief: Results Of A Within-Patient Multiple-Dose Study

Migraine Without Aura | Migraine With Aura

Spain, France, Italy, Netherlands, Turkey, Belgium, Hungary, Czechia, Denmark, Germany, Greece, Norway, Portugal, Sweden
Sanofi
Regeneron Pharmaceuticals

Terminated

Evaluation of Efficacy and Safety of Sarilumab in Patients With GCA

Giant Cell Arteritis

Argentina, Estonia, France, United States, Australia, Belgium, Canada, Croatia, Denmark, Germany, Hungary, Israel, Italy, Netherlands, Portugal, Russian Federation, Slovenia, Spain, Sweden, Switzerland, United Kingdom
Microvention-Terumo, Inc.
ClinSearch

Terminated

PHIL Evaluation in the Endovascular Treatment of Intracranial Cerebral ArterioVenous Malformation (cAVM)

Cerebral AV Malformation

United Kingdom, Spain, Denmark, France, Sweden
Gilead Sciences

Completed

Study of Sacituzumab Govitecan-hziy (IMMU-132) in Adults With Epithelial Cancer

Cervical Cancer | Urinary Bladder Neoplasms | Small Cell Lung Cancer | Hepatocellular Carcinoma | Pancreatic Cancer | Esophageal Cancer | Ovarian Epithelial Cancer | Glioblastoma Multiforme | Gastric Adenocarcinoma | Triple Negative Breast Cancer | Endometrial Cancer | Non-small Cell Lung Cancer | Renal Cell Cancer and other conditions

United States
W.L.Gore & Associates

Recruiting

GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study (REDUCE PAS)

Stroke | PFO - Patent Foramen Ovale

United States
Otsuka Pharmaceutical Development & Commercialization...
H. Lundbeck A/S

Completed

Safety Follow-up Study for Subjects With Agitation Associated With Dementia of the Alzheimer's Type Who Previously Participated in a Double-blind Trial of Brexpiprazole or Placebo

Nervous System Diseases | Mental Disorder | Alzheimer's Type | Agitation Associated With Alzheimer's Disease

United States, Germany, France, Bulgaria, Spain, Slovenia, Croatia, Serbia, Russian Federation, Ukraine, Canada, United Kingdom
Eli Lilly and Company

Recruiting

A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)

Mental Disorders | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Neurocognitive Disorders | Neurodegenerative Diseases | Dementia | Alzheimer Disease | Tauopathies

China, Australia, Taiwan, Korea, Republic of, United Kingdom, Argentina
Vaccinex Inc.
Huntington Study Group

Completed

A Study in Subjects With Late Prodromal & Early Manifest HD to Assess the Safety, Tolerability, pk, and Efficacy of Pepi (SIGNAL-HD)

Huntington's Disease

United States, Canada
Medtronic Neurovascular Clinical Affairs

Recruiting

Embolization of the Middle Meningeal Artery With ONYX™ Liquid Embolic System for Subacute and Chronic Subdural Hematoma (EMBOLISE)

Subdural Hematoma

United States

Clinical Trials on Brain Stem Gliomas in United States

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