Clinical Trials on Brain Pathology

Total 251858 results

Novartis Pharmaceuticals

Completed

Medical Safety Follow-up Study for Patients Who Received More Than 28 Days of Total Exposure to BGG492

Adrenocortical Adenoma | Endometrial Stromal Sarcomas

Germany, United States, Korea, Republic of, Hungary, Italy, Slovakia
GlaxoSmithKline

Completed

Immunogenicity and Safety of a DTPa-HBV-IPV/Hib Vaccine Given at 2, 3 and 4 Months of Age

Hepatitis B | Tetanus | Diphtheria | Acellular Pertussis | Poliomyelitis | Haemophilus Influenzae Type b

Finland
National Institute of Allergy and Infectious Diseases...
Autoimmunity Centers of Excellence

Terminated

T and B Cell Responses in Autoimmune Diseases (SRA01)

Multiple Sclerosis | Arthritis, Rheumatoid | Psoriasis | Crohn's Disease | Type 1 Diabetes Mellitus

United States
Sanofi Pasteur, a Sanofi Company

Completed

Study of the Safety of Menactra® Vaccine When Administered With Other Pediatric Vaccines to Healthy Toddlers

Measles | Rubella | Mumps | Varicella | Meningococcal Meningitis

United States, Chile
University of Sao Paulo

Unknown

Small Bowel Endoscopic Evaluation in Familial Adenomatous Polyposis (FAP)

Familial Adenomatous Polyposis

Brazil
University of Washington
National Cancer Institute (NCI); GlaxoSmithKline; National Comprehensive Cancer...

Completed

Iodine I 131 and Pazopanib Hydrochloride in Treating Patients With Recurrent and/or Metastatic Thyroid Cancer Previously Treated With Iodine I 131 That Cannot Be Removed By Surgery

Recurrent Thyroid Cancer | Stage IVA Follicular Thyroid Cancer | Stage IVA Papillary Thyroid Cancer | Stage IVB Follicular Thyroid Cancer | Stage IVB Papillary Thyroid Cancer | Stage IVC Follicular Thyroid Cancer | Stage IVC Papillary Thyroid Cancer

United States
Merck Sharp & Dohme LLC

Completed

A Study to Determine the Management of Palmar-plantar Erythrodysesthesia (PPE) in Patients With Metastatic Ovarian or Breast Cancer Treated With Caelyx (Study P05020)

Breast Neoplasms | Ovarian Neoplasms | Paresthesia
National Cancer Institute (NCI)

Completed

Dasatinib in Treating Patients With Unresectable or Metastatic Squamous Cell Skin Cancer or RAI Stage 0-I Chronic Lymphocytic Leukemia

Squamous Cell Carcinoma of the Skin | Recurrent Skin Cancer | Stage 0 Chronic Lymphocytic Leukemia | Stage I Chronic Lymphocytic Leukemia

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Gemcitabine and Radiation Therapy in Treating Patients With Locally Advanced Upper Gastrointestinal Cancer

Gastric Cancer | Pancreatic Cancer | Small Intestine Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer
National Cancer Institute (NCI)

Completed

Decitabine and Bortezomib in Treating Patients With Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) | Secondary Acute Myeloid Leukemia and other conditions

United States
National Cancer Institute (NCI)

Completed

Gemcitabine Hydrochloride and Tanespimycin in Treating Patients With Recurrent Advanced Ovarian Epithelial or Peritoneal Cavity Cancer

Stage IV Ovarian Epithelial Cancer | Primary Peritoneal Cavity Cancer | Recurrent Ovarian Epithelial Cancer | Stage III Ovarian Epithelial Cancer

United States
Chinese Pulmonary Vascular Disease Research Group

Completed

Long-term Effects of CPAP on Lipidemia and Hs-CRP Levels in OSA Patients

Obstructive Sleep Apnea | Coronary Heart Disease

China
Centers for Disease Control and Prevention
National Center for AIDS/STD Control and Prevention, China CDC

Unknown

A Methadone Maintenance Treatment Outcome Study in Three Provinces in China

Hepatitis C | HIV | Syphilis | Herpes Simplex Type II

China
National Cancer Institute (NCI)

Terminated

Sorafenib Tosylate in Treating Patients With Locally Advanced, Metastatic, or Locally Recurrent Thyroid Cancer

Insular Thyroid Cancer | Recurrent Thyroid Cancer | Stage IV Follicular Thyroid Cancer | Stage IV Papillary Thyroid Cancer | Anaplastic Thyroid Cancer | Stage III Follicular Thyroid Cancer | Stage III Papillary Thyroid Cancer

United States
Sanofi Pasteur, a Sanofi Company

Completed

Study of DTaP-IPV-Hep B-PRP~T Combined Vaccine Compared With PENTAXIM™ and ENGERIX B® PEDIATRICO in Argentinean Infants

Pertussis | Tetanus | Diphtheria | Poliomyelitis | Haemophilus Influenzae Type b

Argentina
St George's, University of London

Terminated

Intrauterine Levonorgestrel and Observation or Observation Alone in Preventing Atypical Endometrial Hyperplasia and Endometrial Cancer in Women With Hereditary Non-Polyposis Colorectal Cancer or Lynch Syndrome

Endometrial Cancer | Hereditary Non-polyposis Colon Cancer (hmsh2, hmlh1, hpms1, hpms2)

United Kingdom
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Diagnostic Study of Tumor Characteristics in Patients With Ewing's Sarcoma

Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor

United States
novoGI

Unknown

A RETROspective Data Collection of comPRESSion Anastomosis Using the ColonRing

Lymphoma | Colorectal Neoplasms | Endometriosis | Crohn Disease | Colitis, Ulcerative | Intestinal Polyposis | Ileostomy - Stoma | Intestinal Volvulus | Colostomy | Diverticulum, Colon | Rectal Prolapse

United States
National Cancer Institute (NCI)

Completed

S0331: Imatinib Mesylate in Treating Patients With Metastatic or Unresectable Merkel Cell Cancer

Recurrent Neuroendocrine Carcinoma of the Skin | Stage III Neuroendocrine Carcinoma of the Skin | Stage II Neuroendocrine Carcinoma of the Skin

United States
National Cancer Institute (NCI)

Completed

Irinotecan Plus Cyclosporine and Phenobarbital in Treating Patients With Solid Tumors or Lymphoma

Lymphoma | Small Intestine Cancer | Neutropenia | Unspecified Adult Solid Tumor, Protocol Specific | Drug/Agent Toxicity by Tissue/Organ

United States
European Organisation for Research and Treatment...

Completed

STI571 in Treating Patients With Recurrent or Refractory Soft Tissue Sarcoma

Sarcoma | Small Intestine Cancer | Ovarian Cancer | Endometrial Cancer | Gastrointestinal Stromal Tumor

France, Denmark, Netherlands, Belgium, United Kingdom
Columbia University

Unknown

Risk-Adapted Allogeneic Stem Cell Transplantation For Mixed Donor Chimerism In Patients With Non-Malignant Diseases

Severe Combined Immunodeficiency | Fanconi Anemia | Bone Marrow Failure | Osteopetrosis

United States
University Hospital, Ghent
Novartis Pharma AG, Switzerland

Completed

Clinical and Biological Effects of Anti-IgE (Omalizumab) in Patients With Bilateral Nasal Polyposis and Asthma

Asthma | Nasal Polyposis

Belgium
ARCAGY/ GINECO GROUP

Completed

Use of FACT-GOG/NTX Questionnaire in Peripheral Neurotoxicity & Validation of a French Version of This Questionnaire

Peritoneal Neoplasms | Ovarian Cancer | Fallopian Tube Cancer

France
Chang Gung Memorial Hospital

Unknown

The Effectiveness of Improving Self-care After Counseling for the Diabetics Mellitus Foots Around Chiayi Region

Diabetic Foot | Type 2 Diabetes Mellitus With Established Diabetic Nephropathy

Taiwan
Pharmacyclics LLC.

Completed

Study of Motexafin Gadolinium and Docetaxel for Advanced Cancer

Gastrointestinal Neoplasms | Breast Neoplasms | Lung Neoplasms | Prostatic Neoplasms | Ovarian Neoplasms

United States
Norwegian Institute of Public Health

Completed

Immunogenicity and Safety Study of a Booster Dose (5th) of Diphteria-Tetanus-Pertussis-Polio Vaccine

Pertussis | Tetanus | Diphtheria | Polio

Norway
University of Washington
Agency for Healthcare Research and Quality (AHRQ)

Completed

A Trial of Point of Care Information in Ambulatory Pediatrics

Constipation | Sinusitis | Allergic Rhinitis | Bronchiolitis | Urticaria | Pharyngitis | Croup | Acute Otitis Media

United States
National Institute of Allergy and Infectious Diseases...
National Institute on Drug Abuse (NIDA); National Institute of Diabetes and... and other collaborators

Unknown

Observational Study of Changes in Fat Distribution and Blood Metabolites in HIV Infected Adults

HIV Infections | Diabetes | Atherosclerosis | Hyperlipidemia | Lipodystrophy
King's College Hospital NHS Trust
University College, London

Active, not recruiting

The Accuracy of Ultrasound Diagnosis of Hydatidiform Moles

Abortion, Spontaneous | Missed Abortion | Miscarriage in First Trimester | Incomplete Miscarriage | Hydatidiform Mole (Diagnosis)

United Kingdom
Columbia University
National Institute on Alcohol Abuse and Alcoholism (NIAAA); University of Alabama... and other collaborators

Terminated

Zambia Common Elements Treatment Approach Pilot Study (ZCAP)

Depression | HIV/AIDS | Substance Use Disorders | Alcohol Use Disorder | Post-traumatic Stress Disorder

Zambia
Creighton University
AstraZeneca

Completed

Trial of Seroquel SR for Alcohol Dependence and Comorbid Anxiety

Alcoholism | Obsessive-Compulsive Disorder | Anxiety Disorders | Generalized Anxiety Disorder | Panic Disorder | Post-Traumatic Stress Disorder

United States
European Institute of Oncology
University of Rome Tor Vergata

Recruiting

Volatolomic and Proteomic Profile for Early Diagnosis of Lung Cancer

Lung Cancer | Non-small Cell Lung Cancer Stage I | Non-small Cell Lung Cancer Stage II | Lung Cancer Diagnosis

Italy
Oslo University Hospital
Centre for Appearance Research, University of the West of England, UK

Enrolling by invitation

Online Psychosocial Support for Young People With a Visible Difference: A Randomised Control Study (UNGFaceIT)

Burns | Cleft Lip and Palate | Craniofacial Abnormalities | Skin Condition | Other Conditions Leading to a Visible Difference

Norway
Medical University of South Carolina
United States Department of Defense; Institute for Translational Neuroscience

Completed

NAC for Treating Comorbid PTSD and SUD (DoD-NAC)

Alcohol Use Disorder (AUD) | Posttraumatic Stress Disorder (PTSD) | Substance Use Disorder (SUD)

United States
Medical Research Council Cognition and Brain Sciences...
Cambridgeshire and Peterborough NHS Foundation Trust

Completed

The Modular Protocol for Mental Health (MPMH) (MPMH)

Obsessive-Compulsive Disorder | Generalized Anxiety Disorder | Major Depressive Disorder | Posttraumatic Stress Disorder | Social Anxiety Disorder | Panic Disorder | Agoraphobia | Illness Anxiety Disorder

United Kingdom
University of Washington
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institute... and other collaborators

Completed

A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity Pilot (TSOS6)

Substance-Related Disorders | Depression | Alcohol-Related Disorders | Quality of Life | Suicidal Ideation | Mild Cognitive Impairment | Posttraumatic Stress Disorder
John Mitchell

Completed

Sleep and Quality of Life in Patients With Glycogen Storage Disease on Standard Versus Modified Uncooked Cornstarch

Glycogen Storage Disease Type III | Glycogen Storage Disease Type IA | Glycogen Storage Disease Type IB | Glycogen Storage Disease Type 0

Canada
Yale University
Health Resources and Services Administration (HRSA); The New York Academy of... and other collaborators

Completed

Integration of Buprenorphine Into HIV Clinical Settings - Primary Care Model (PCM) (BELIEVE)

HIV | Substance Abuse | Drug Abuse | Substance-related Disorders | Drug Addiction | Opiate Addiction | Drug Use Disorder | Buprenorphine | Drug Dependence | Drug Use Disorders

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Active, not recruiting

Gene-Modified T Cells With or Without Decitabine in Treating Patients With Advanced Malignancies Expressing NY-ESO-1

Metastatic Melanoma | Advanced Malignant Solid Neoplasm | Unresectable Melanoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIB Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Pathologic Stage IIID Cutaneous Melanoma AJCC v8 | Pathologic Stage... and other conditions

United States
Chimagen Biosciences, Ltd

Recruiting

First-in-Human (FIH) Trial of 1A46 in Subjects With Advanced CD20 and/or CD19 Positive B-cell Hematologic Malignancies

Non-Hodgkin's Lymphoma (Disorder) | Acute Lymphoid Leukemia, Disease (Disorder)

United States
Mental Health Services in the Capital Region, Denmark

Recruiting

The OPUS YOUNG Trial. Early Intervention Versus Treatment as Usual for Adolescents With First-episode Psychosis (OPUS-YOUNG)

Schizophrenia | Schizoaffective Disorder | Delusional Disorder | Depression Severe | Schizotypal Disorder | Acute and Transient Psychotic Disorder, Unspecified | Non-Organic Psychosis | Substance Induced Psychoses

Denmark
Chinese University of Hong Kong

Recruiting

Archival of Human Biological Samples in CU-Med Biobank

Heart Diseases | Kidney Diseases | Healthy | Diabetes | Cancer | Neurological Diseases or Conditions | Other Disease

Hong Kong
Medical University of Gdansk

Enrolling by invitation

Observation of Ketamine Treatment Safety and Tolerability in Adult Psychiatry Clinic Medical University of Gdańsk Inpatients (KetGD)

Obsessive-Compulsive Disorder | Anxiety Disorders | Somatoform Disorders | Post Traumatic Stress Disorder | Major Depressive Disorder | Dissociative Disorder

Poland
University of South Florida

Unknown

Neurophysiological Mechanisms of Accelerated Resolution Therapy (ART) (M-ART)

Stress Disorders, Post-Traumatic | Depressive Symptoms | Alcohol Abuse | Prolonged Grief Disorder | Stress Disorder, Acute

United States
CSL Behring

Completed

Study of Safety and Efficacy of Antihemophilic Factor/Von Willebrand Factor Complex in Surgical Subjects With Von Willebrand Disease (vWD)

Blood Coagulation Disorders | Blood Platelet Disorders | Hematologic Disease | Von Willebrand Disease

United States
Marcelo Bonomi

Recruiting

Cemiplimab, Low-Dose Paclitaxel and Carboplatin for the Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Metastatic Head and Neck Squamous Cell Carcinoma | Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC... and other conditions

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Innovative SonoCloud-9 Device for Blood Brain Barrier Opening in First Line Temozolomide Glioblastoma Patients. (SonoFIRST)

Initial Radiological Diagnosis Eligible for Tumor Resection | Initial Radiological Diagnosis Compatible With Newly Diagnosed Glioblastoma (IDH Wild-type) | Eligible for the Standard of Care Including Concurrent Temoradiation and Adjuvant Temozolomide

Belgium, France, Switzerland
The University of Texas Health Science Center,...
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Unknown

Imaging Lymphatic Function in Normal Subjects and in Persons With Lymphatic Disorders

Lymphedema | Dercum Disease | Lipedema | Vascular Anomaly | Vascular Malformation | Lymphatic Disorders

United States
National Taiwan University Hospital

Unknown

The Study of p62/SQSTM1 as a Malignant Transformation Marker for Oral Potentially Malignant Disorders and a Prognostic Marker for Oral Squamous Cell Carcinoma (p62/SQSTM1)

Oral Cancer | Oral Potentially Malignant Disorder | Malignant Disorder | p62/SQSTM1

Clinical Trials on Brain Pathology

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