Clinical Trials on CANDLE Syndrome

Total 36735 results

Janssen Research & Development, LLC

Completed

A Study of Guselkumab in Participants With Familial Adenomatous Polyposis

Adenomatous Polyposis Coli

United States, Germany, France, Israel, Netherlands, Poland, Puerto Rico, Spain, Sweden
Janssen Research & Development, LLC

Completed

A Study of JNJ-64251330 in Participants With Familial Adenomatous Polyposis

Adenomatous Polyposis Coli

United States, Germany, Korea, Republic of, France, Netherlands, Spain, Puerto Rico
Academisch Medisch Centrum - Universiteit van Amsterdam...

Enrolling by invitation

The CHAMP-study: The CHemopreventive Effect of Lithium in Familial AdenoMatous Polyposis (Lithium in FAP)

Familial Adenomatous Polyposis

Netherlands
CENTOGENE GmbH Rostock

Completed

Biomarker for Hereditary AngioEdema Disease (BioHAE)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | C1 Esterase Inhibitor Deficiency | HAE | Angio Edema | C4 Deficiency | Hereditary Angioedema Type III

Turkey, Armenia, Georgia, India, Peru, Poland, Romania
Janssen Research & Development, LLC

No longer available

Post-Trial Access for Guselkumab in Participants With Familial Adenomatous Polyposis

Adenomatous Polyposis Coli
Hospital de Clinicas de Porto Alegre

Completed

Cheeks Appearance as a Novel Predictor of Obstructive Sleep Apnea The CASA Score Study (CASA)

Muscle Weakness | Obstructive Sleep Apnea | Swallowing Disorder | Muscle Disorder | Face | Breathing, Sleep-Disordered

Brazil
Central Hospital, Nancy, France

Enrolling by invitation

Additional Autoimmune Diseases With Type 1 Diabetes in Pediatrics at Diabetes Diagnosis and During Follow-up (AADT1D)

Autoimmune Diseases | Type 1 Diabetes | Graves Disease | Celiac Disease | Vitiligo | Hashimoto Disease | Addison Disease

France
Pfizer's Upjohn has merged with Mylan to form Viatris...

Terminated

Trial In Pediatric Patients With Familial Adenomatous Polyposis (FAP) (CHIP)

Adenomatous Polyposis Coli

Italy, United States, Belgium, Spain, Puerto Rico, Sweden, Israel, Czechia, Hong Kong, Hungary, Slovakia, South Africa, Ukraine, United Kingdom
Uptown Eye Specialists

Unknown

Obstructive Sleep Apnea and Diabetic Macular Edema Inflammatory Mediators

Diabetic Retinopathy | Diabetic Macular Edema | Obstructive Sleep Apnea

Canada
National Institute of Mental Health (NIMH)

Terminated

PET Evaluation of Brain Peripheral Benzodiazepine Receptors Using [11C]PBR28 in HIV-Seropositive Patients With (MCMD)

HIV Infections | Healthy | AIDS Dementia Complex | AIDS-Related Dementia Complex | HIV-Associated Cognitive Motor Complex | HIV-Dementia | AIDS Encephalopathy

United States
National Cancer Institute (NCI)

Completed

Ziv-Aflibercept in Treating and Computed Tomography Perfusion Imaging in Predicting Response in Patients With Pancreatic Neuroendocrine Tumors That Are Metastatic or Cannot Be Removed by Surgery

Pancreatic Neuroendocrine Carcinoma | Multiple Endocrine Neoplasia Type 1

United States
University Hospital, Essen

Completed

HIV&HEART Aging Study (12,5 Year Follow up) (HIV&HEART)

Myocardial Infarction | HIV Infections | Heart Failure | Coronary Disease | Aging | HIV Encephalopathy

Germany
National Cancer Institute (NCI)

Completed

Phase I Study of Ipilimumab (Anti-CTLA-4) in Children and Adolescents With Treatment-Resistant Cancer

Sarcoma | Lymphoma | Neuroblastoma | Wilm's Tumor

United States
Merck Sharp & Dohme LLC

Terminated

A Study of Rofecoxib in Familial Adenomatous Polyposis (FAP) (0966-205)(TERMINATED)

Adenomatous Polyposis Coli
University College, London
University of Iowa

Unknown

Muscle MRI in Charcot Mary Tooth Disease: a Prospective Cohort Study

Charcot-Marie-Tooth Disease, Type IA | Charcot-Marie-Tooth Disease Type 2A | Charcot-Marie-Tooth Disease, Type IB | Charcot-Marie-Tooth Disease, Type X

United Kingdom
New York Medical College

Terminated

ODSH + ICE Chemotherapy in Pediatric Solid Tumors

Sarcoma | Neuroblastoma | Wilms' Tumor | Refractory Solid Tumor | Recurrent Solid Tumor

United States
University Hospital, Bonn

Unknown

Incidence and Effects of Sleep Apnea on Intracerebral Aneurysms (IESA)

Comorbidities | Sleep Apnea (Defined as Apnea Hypopnea Index > 5/h) | Intracranial Aneurysm Size | Blood Pressure Medication | Complications (Subarachnoid Hemorrhage)

Germany
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Homocysteine and Progression of Atherosclerosis

Myocardial Infarction | Heart Diseases | Cardiovascular Diseases | Cerebrovascular Disorders | Peripheral Vascular Diseases | Atherosclerosis | Hyperhomocysteinemia
University of Sao Paulo

Unknown

Small Bowel Endoscopic Evaluation in Familial Adenomatous Polyposis (FAP)

Familial Adenomatous Polyposis

Brazil
Chinese Pulmonary Vascular Disease Research Group

Completed

Long-term Effects of CPAP on Lipidemia and Hs-CRP Levels in OSA Patients

Obstructive Sleep Apnea | Coronary Heart Disease

China
St George's, University of London

Terminated

Intrauterine Levonorgestrel and Observation or Observation Alone in Preventing Atypical Endometrial Hyperplasia and Endometrial Cancer in Women With Hereditary Non-Polyposis Colorectal Cancer or Lynch Syndrome

Endometrial Cancer | Hereditary Non-polyposis Colon Cancer (hmsh2, hmlh1, hpms1, hpms2)

United Kingdom
ARCAGY/ GINECO GROUP

Completed

Use of FACT-GOG/NTX Questionnaire in Peripheral Neurotoxicity & Validation of a French Version of This Questionnaire

Peritoneal Neoplasms | Ovarian Cancer | Fallopian Tube Cancer

France
National Cancer Institute (NCI)

Terminated

Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating Young Patients With Relapsed or Refractory Solid Tumors, Lymphoma, or Leukemia

Unspecified Childhood Solid Tumor, Protocol Specific | Peripheral T-cell Lymphoma | Angioimmunoblastic T-cell Lymphoma | Childhood Chronic Myelogenous Leukemia | Cutaneous B-cell Non-Hodgkin Lymphoma | Hepatosplenic T-cell Lymphoma | Intraocular Lymphoma | Recurrent Childhood Acute Lymphoblastic... and other conditions

United States, Canada
Bicara Therapeutics
Merck Sharp & Dohme LLC

Recruiting

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

Head and Neck Neoplasms | Carcinoma, Squamous Cell | Colorectal Cancer | Squamous Cell Carcinoma of Head and Neck | Epithelial Ovarian Cancer | Head and Neck Squamous Cell Carcinoma | Pancreas Cancer | Squamous Cell Carcinoma of the Lung | Cutaneous Squamous Cell Carcinoma | Squamous Cell Carcinoma of... and other conditions

United States, Canada
Medical University of Graz

Not yet recruiting

Prevalence of ENT Diseseas (PrENT)

HPV Infection | HPV Vaccine | Rhinosinusitis Chronic | Long COVID | Rhinosinusitis | ENT Surgery | ENT Disease | Conscripts | Military Induction Board
Avidity Biosciences, Inc.

Recruiting

Phase 1/2 Study of AOC 1020 in Adults With Facioscapulohumeral Muscular Dystrophy (FSHD) (FORTITUDE)

Muscular Dystrophies | Muscular Dystrophy, Facioscapulohumeral | FSHD | Facio-Scapulo-Humeral Dystrophy | FMD | Facioscapulohumeral Muscular Dystrophy 1 | FSHD2 | FSHD1 | FMD2 | Fascioscapulohumeral Muscular Dystrophy | Fascioscapulohumeral Muscular Dystrophy Type 1 | Fascioscapulohumeral Muscular Dystrophy... and other conditions

United States, United Kingdom, Canada
National Cancer Institute (NCI)

Active, not recruiting

Pazopanib Hydrochloride in Treating Patients With Progressive Carcinoid Tumors

Metastatic Digestive System Neuroendocrine Tumor G1 | Recurrent Digestive System Neuroendocrine Tumor G1 | Regional Digestive System Neuroendocrine Tumor G1 | Metastatic Neuroendocrine Tumor | Midgut Neuroendocrine Tumor G1 | Foregut Neuroendocrine Tumor | Hindgut Neuroendocrine Tumor | Neuroendocrine...

Canada, United States
Yang I. Pachankis, PhD
S for Science

Active, not recruiting

Psychiatric Orders in Psychoanalytic Treatment of ASD

PTSD | Anxiety Disorders | OCD | Borderline Personality Disorder | Social Anxiety Disorder | Depression, Anxiety | Depression, Unipolar | ADHD - Combined Type | Grief | Depression Anxiety Disorder | Depression and Suicide | Autism Spectrum Disorder High-Functioning | Avoidant Personality Disorder | Agoraphobia With... and other conditions

China
Hospital Universitario Virgen Macarena
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla

Enrolling by invitation

Clinical Outcomes in Patients With Infection by Resistant Microorganism

Pneumonia | Staphylococcus Aureus | Urinary Tract Infections | Surgical Site Infection | Escherichia Coli | Bloodstream Infection | Acinetobacter Infections | Pseudomonas Aeruginosa | Skin Infection | Klebsiella Pneumonia | Enterococcus Faecium Infection

Spain
Sun Yat-sen University

Active, not recruiting

Guangzhou Nutrition and Health Study (GNHS) (GNHS)

Cardiovascular Diseases | Hypertension | Obesity | Diabetes Mellitus, Type 2 | Cancer | Chronic Kidney Diseases | Nutrition Disorders | Death | Metabolic Syndrome | Sarcopenia | Osteoporosis | Non-Alcoholic Fatty Liver Disease
East Kent Hospitals University NHS Foundation Trust
KU Leuven; University of Kent; Sussex Community NHS Foundation Trust; l'Institut...

Completed

An Assistive Powered Wheelchair: Stage 2 Trial (EDUCAT)

Stroke | Multiple Sclerosis | Craniocerebral Trauma | Cystic Fibrosis | Guillain-Barre Syndrome | Motor Neurone Disease

United Kingdom
Gillette Children's Specialty Healthcare

Completed

Effects of Standing on Non-Ambulatory Children With Neuromuscular Conditions

Cerebral Palsy | Muscular Dystrophy | Osteopenia | Rett Syndrome | Spinal Muscular Atrophy | Spina Bifida

United States
University of Split, School of Medicine
General Hospital Zadar

Unknown

QoL and Stress in Parents of Children With Developmental Disabilities and Chronic Disease

Epilepsy | Cerebral Palsy | Diabetes Mellitus, Type 1 | Stress | Asthma | Chronic Disease | Autism Spectrum Disorder | Down Syndrome | Developmental Disability | Pervasive Developmental Disorder

Croatia
University of Basel
Kantonsspital Aarau

Completed

Prevention of Conversion in Posterior Retroperitoneal Adrenalectomy by Measuring Preoperative Anatomical Conditions

Pheochromocytoma | Adrenal Tumor | Adrenal Mass | Adrenal Hyperplasia | Adrenal Metastases | Conn Adenoma

Switzerland
Montefiore Medical Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Interferon Alfa Followed by Filgrastim in Treating Patients With Gastrointestinal Tract Cancer

Gastric Cancer | Pancreatic Cancer | Small Intestine Cancer | Liver Cancer | Extrahepatic Bile Duct Cancer | Gastrointestinal Carcinoid Tumor

United States
Assistance Publique - Hôpitaux de Paris

Completed

Association Corticosteroid/Azathioprine in Microscopic Polyangiitis/ Polyarteritis Nodosa or Eosinophilic Granulomatosis With Polyangiitis (Churg Strauss Syndrome) (CHUSPAN2)

MPA | PAN or EGPA With FFS=0 | At Diagnosis or Within the First 15 Days Following Initiation of Corticosteroids

France
Neuroganics LLC
Ramos Injury Law Firm

Recruiting

National Vaccine Adverse Event Reporting Survey and Etiology (NVAERS)

COVID-19 | Vaccine Adverse Reaction | Vaccine Reaction | Vasculitis | Neuritis | Thrombocytopenia | Influenza | Corona Virus Infection | Blood Clot | Guillain-Barré | Vaccine or Biological Substance, Unspecified Causing Adverse Effects in Therapeutic Use | GWAS | Genetic Sequencing

United States
University Hospital, Strasbourg, France

Recruiting

Cerebro Spinal Fluid Collection (CSF) (Analzheimer)

Alzheimer Disease | Multiple System Atrophy | Frontotemporal Dementia | Dementia With Lewy Bodies | Parkinson's Disease Dementia

France
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Copanlisib and Nivolumab in Treating Patients With Richter's Transformation or Transformed Indolent Non-Hodgkin Lymphoma

Follicular Lymphoma | Diffuse Large B-Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Lymphoplasmacytic Lymphoma | Richter Syndrome | Indolent Non-Hodgkin Lymphoma

United States
Novo Nordisk A/S

Completed

Evaluating Acceptance of New Liquid Somatropin Formulation in Children With Growth Hormone Deficiency

Turner Syndrome | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Genetic Disorder

Israel
National Taiwan University Hospital
National Cheng-Kung University Hospital

Unknown

Mitochondrial nt3243 A>G Mutation in Taiwan

MELAS Syndrome | Noninsulin-dependent Diabetes Mellitus With Deafness

Taiwan
Children's Hospitals and Clinics of Minnesota
M.D. Anderson Cancer Center; Washington University School of Medicine; Dana-Farber... and other collaborators

Recruiting

International PPB/DICER1 Registry

Neuroblastoma | Thyroid Carcinoma | Pineoblastoma | Wilms Tumor | Embryonal Rhabdomyosarcoma | Ovarian Sarcoma | Sertoli-Leydig Cell Tumor | Pleuropulmonary Blastoma | Gynandroblastoma | DICER1 Syndrome | Cystic Nephroma | Renal Sarcoma | Nodular Hyperplasia of Thyroid | Nasal Chondromesenchymal Hamartoma | Ciliary Body... and other conditions

United States
University of Dublin, Trinity College
Motor Neurone Disease Association, UK; Irish Research Council, IE; Thierry Latran... and other collaborators

Recruiting

Non-invasive Spinal, Cortical, and Sensorimotor Biomarkers in Motor Neurone Disease

Multiple Sclerosis | Primary Lateral Sclerosis | Postpoliomyelitis Syndrome | Motor Neuron Disease, Amyotrophic Lateral Sclerosis | Motor Neuron Disease Progressive Spinal Muscle Atrophy

Ireland
University of Rochester
University of Colorado, Denver; Massachusetts General Hospital; Stanford University

Recruiting

Community Outreach for Palliative Engagement -- Parkinson Disease (COPE-PD)

Parkinson Disease | Multiple System Atrophy | Corticobasal Degeneration | Progressive Supranuclear Palsy | Parkinson's Disease and Parkinsonism | Dementia With Lewy Bodies | Vascular Parkinsonism | Parkinson Disease Dementia | Lewy Body Parkinsonism

United States
NYU Langone Health

Recruiting

Natural History Study of Synucleinopathies

Parkinson Disease | Multiple System Atrophy | Neurogenic Orthostatic Hypotension | REM Sleep Behavior Disorder | Pure Autonomic Failure | Dementia With Lewy Bodies | Patients With Synucleinopathies | Shy-Drager Disease

Korea, Republic of, United States, Argentina, Spain
Reata, a wholly owned subsidiary of Biogen

Completed

Bardoxolone Methyl Evaluation in Patients With Pulmonary Hypertension (PH) - LARIAT

Idiopathic Pulmonary Fibrosis | Pulmonary Arterial Hypertension | Pulmonary Hypertension | Interstitial Lung Disease | Sarcoidosis | Idiopathic Interstitial Pneumonia | Cryptogenic Organizing Pneumonia | Desquamative Interstitial Pneumonia | Respiratory Bronchiolitis Associated Interstitial Lung Disease and other conditions

United States, Germany
Sheba Medical Center

Enrolling by invitation

Brain Network Activation in Patients With Movement Disorders (BNA-MDi)

Parkinson Disease | Cerebellar Ataxia | Dystonia | Multiple System Atrophy | Corticobasal Degeneration | Progressive Supranuclear Palsy | Essential Tremor | Dementia With Lewy Bodies | Normal Pressure Hydrocephalus

Israel
University of Pennsylvania

Completed

Cognitive Impairement In Frontotemporal Dementia

Frontotemporal Degeneration | Multiple System Atrophy | Progressive Supranuclear Palsy

United States
Brigham and Women's Hospital
Northeastern University

Completed

Patient Safety Learning Laboratory: Making Acute Care More Patient-Centered (PSLL)

Venous Thromboembolism | Patient Fall | Adverse Drug Event | Severe Hypoglycemia | Hospital Acquired Pressure Ulcer | Central Line-Associated Bloodstream Infection (CLABSI) | Catheter-Associated Infection | Opioid-Related Severe Adverse Drug Event | Severe Hospital Acquired Delerium | Rapid Response Related...

United States
University of Oxford
Wellcome Trust; National Institute for Health Research, United Kingdom; Arthritis...

Completed

Epidemiology and Outcomes of Upper Limb Surgery: Analysis of Routine Data

Osteoarthritis | Rotator Cuff Tear | Avascular Necrosis | Inflammatory Arthritis | Shoulder Dislocation | Dupuytren Contracture | Impingement Syndrome, Shoulder | Elbow Arthropathy | Trigger Digit | Shoulder Arthropathy | Upper Limb Nerve Lesion | Wrist Arthropathy | Fracture Elbow | Dislocations | Fracture, Shoulder | Arthropathy... and other conditions

Clinical Trials on CANDLE Syndrome

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Medical Conditions

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CROs in Malawi

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