Clinical Trials on CLL, Refractory

Total 437216 results

Sociedad Espanola del Dolor

Recruiting

Effectiveness and Safety of Implantable Intrathecal Systems for Refractory Pain in Spain (INTRATHECAL-RENASED)

Refractory Pain

Spain
Abbott Medical Devices

Active, not recruiting

Implantation of the HeartMate 3 in Subjects With Heart Failure Using Surgical SWIFT HM3 PMS (SWIFT)

Advanced Refractory Left Ventricular Heart Failure

United States, Canada
Abbott Medical Devices

Completed

MOMENTUM 3 Continued Access Protocol (MOMENTUM 3 CAP)

Advanced Refractory Left Ventricular Heart Failure

United States
Assistance Publique - Hôpitaux de Paris

Unknown

Refractory Ascitis Diagnosis by the Study of Labelled Albumin Pharmacokinetics (ARAM)

Refractory Ascites in Patients With Cirrhosis

France
National Cancer Institute (NCI)

Active, not recruiting

Testing the Sequential Combination of the Anti-cancer Drugs Olaparib Followed by Adavosertib (AZD1775) in Patients With Advanced Solid Tumors With Selected Mutations and PARP Resistance, STAR Study

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Pembrolizumab and Pralatrexate in Treating Patients With Relapsed or Refractory Peripheral T-Cell Lymphomas

Anaplastic Large Cell Lymphoma | Recurrent Angioimmunoblastic T-Cell Lymphoma | Recurrent Mycosis Fungoides | Refractory Angioimmunoblastic T-Cell Lymphoma | Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma | Refractory Mycosis Fungoides | Refractory Anaplastic Large Cell Lymphoma | Subcutaneous... and other conditions

United States
University Hospital, Toulouse
Dixi Medical; Centre de recherche Cerveau et Cognition (CERCO)

Recruiting

Contribution of Fast-ripples to the Improvement of the Neurosurgical Management of Drug-refractory Epilepsy (NENUFAR)

Epilepsy

France
Beijing Pins Medical Co., Ltd
Peking University First Hospital; Beijing Tiantan Hospital

Recruiting

Rechargeable Implantable Vagus Nerve Stimulation System for Drug-Refractory Epilepsy

Drug-Refractory Epilepsy

China
Abbott Medical Devices
Thoratec Corporation; KCRI; Center for Life Sciences; Emergo

Completed

HeartMate 3™ CE Mark Clinical Investigation Plan (HM3 CE Mark)

Advanced Refractory Left Ventricular Heart Failure

Germany, Australia, Austria, Canada, Czechia, Kazakhstan
Abbott Medical Devices
Thoratec Corporation

Completed

MOMENTUM 3 IDE Clinical Study Protocol (HM3™)

Advanced Refractory Left Ventricular Heart Failure

United States
Abbott Medical Devices

Completed

MOMENTUM 3 Pivotal Cohort Extended Follow-up PAS

Advanced Refractory Left Ventricular Heart Failure

United States
Samsung Medical Center

Active, not recruiting

Patients With Refractory, Metastatic Cancer Harboring KIT Mutation or Amplification to Investigate the Clinical Efficacy and Safety of Imatinib Therapy

Advanced, Refractory Cancer

Korea, Republic of
Second Affiliated Hospital, School of Medicine,...

Unknown

MRI Study of Antidepressants in the Treatment of Refractory Functional Dyspepsia

Therapeutic Mechanism of Antidepressants for Refractory FD

China
Elsan

Recruiting

Transcranial Direct-current Stimulation (tDCS) Efficacy in Refractory Cancer Pain. (STIMPAL)

Cancer Pain | Refractory Pain

France
Pusan National University Yangsan Hospital

Recruiting

Continuous IntraVenous Infusion of Ketamine in Terminally Ill Cancer Patients (CIVIK)

Ketamine | Refractory Cancer Pain

Korea, Republic of
Xijing Hospital

Completed

cTBS Targeting Cerebellum for Drug-refractory Epilepsy

Drug Refractory Epilepsy

China
Abbott Medical Devices

Completed

HeartMate 3 CE Mark Study Long Term Follow-up (HM3 CE LTFU)

Advanced Refractory Left Ventricular Heart Failure

Germany, Canada, Austria, Czechia, Kazakhstan, Australia
Erasme University Hospital

Completed

UAS-RBS: a Safety Study

Refractory Benign Strictures

Belgium
Astellas Pharma Global Development, Inc.

Completed

A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Escalating Doses of AGS67E Given as Monotherapy in Subjects With Refractory or Relapsed Lymphoid Malignancies

Relapsed Lymphoid Malignancy | Refractory Lymphoid Malignancy

United States, Canada
University of Aarhus

Terminated

Electroconvulsive Therapy for Treatment Refractory Schizophrenia - A Randomized, Double-blinded, Sham-controlled Study

Treatment-refractory Schizophrenia
Emory University

Completed

Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors (AflacST1501)

Diffuse Intrinsic Pontine Glioma | Brain Tumor, Recurrent | Solid Tumor, Recurrent | Neuroblastoma, Recurrent, Refractory | Ewing Sarcoma, Recurrent, Refractory | Rhabdomyosarcoma, Recurrent, Refractory | Osteosarcoma, Recurrent, Refractory | Rhabdoid Tumor, Recurrent, Refractory

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

CD19-Directed CAR-T Cell Therapy for the Treatment of Relapsed/Refractory B Cell Malignancies

Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent Small Lymphocytic Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Refractory Chronic Lymphocytic Leukemia | Recurrent Chronic Lymphocytic Leukemia | Refractory Small Lymphocytic Lymphoma | Recurrent Transformed Chronic Lymphocytic Leukemia | Refractory...

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Active, not recruiting

R-ICE and Lenalidomide in Treating Patients With First-Relapse/Primary Refractory Diffuse Large B-Cell Lymphoma

Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent... and other conditions

United States
AstraZeneca

Active, not recruiting

Study of Acalabrutinib in Chinese Adult Subjects With Relapsed or Refractory Mantle Cell Lymphoma, Chronic Lymphocytic Leukemia or Other B-cell Malignancies

Phase I: Relapsed or Refractory B-cell Malignancies | Phase II Cohort A: Relapsed or Refractory Mantle Cell Lymphoma | Phase II Cohort B: Relapsed or Refractory Chronic Lymphocytic Leukemia

China
Institut de Recherches Internationales Servier
ADIR, a Servier Group company

Completed

Study of a New Intravenous Drug, Called S65487, in Patients With Acute Myeloid Leukemia, Non Hodgkin Lymphoma, Multiple Myeloma or Chronic Lymphocytic Leukemia

Relapsed or Refractory Multiple Myeloma | Relapsed or Refractory Acute Myeloid Leukemia | Relapsed or Refractory Non-Hodgkin Lymphoma | Relapsed or Refractory Chronic Lymphocytic Leukemia

United Kingdom, Spain, France, Australia
Nantes University Hospital

Completed

Multi-centric Study (CHEPRALL)

B ALL | CD22+ Expression | Refractory B-ALL

France
Central Hospital, Nancy, France
Inserm U954 - N-GERE (Nutrition, Genetics and Exposition to Environmental...

Unknown

High Risk Myelodysplasia Treated by Azacytidine : Genetic and Epigenetic (MYRAGE) (MYRAGE)

High-risk Myelodysplastic Syndromes With Excess Blasts

France
Children's Oncology Group
National Cancer Institute (NCI); ImmunoGen, Inc.

Withdrawn

A Study of the Drug IMGN632 in Children With Leukemia That Has Come Back After Treatment or is Difficult to Treat

Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Recurrent B Acute Lymphoblastic Leukemia | Refractory B Acute Lymphoblastic Leukemia | Recurrent Mixed Phenotype Acute Leukemia | Refractory Mixed Phenotype Acute Leukemia | Refractory T Acute Lymphoblastic Leukemia | Recurrent...
Byondis B.V.

Not yet recruiting

Safety, Pharmacokinetics, and Preliminary Efficacy of BYON4413 in Acute Myeloid Leukemia and Myelodysplastic Neoplasms.

Relapsed / Refractory AML | Relapsed / Refractory MDS
National Cancer Institute (NCI)

Active, not recruiting

Testing Trametinib as a Potential Targeted Treatment in Cancers With NF1 Genetic Changes (MATCH-Subprotocol S1)

Hematopoietic and Lymphoid Cell Neoplasm | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma

United States
National Cancer Institute (NCI)

Recruiting

Volitinib in Treating Patients With Recurrent or Refractory Primary CNS Tumors

Recurrent Malignant Glioma | Recurrent Medulloblastoma | Refractory Malignant Glioma | Refractory Medulloblastoma | Recurrent Diffuse Intrinsic Pontine Glioma | Recurrent Primary Central Nervous System Neoplasm | Refractory Primary Central Nervous System Neoplasm | Refractory Diffuse Intrinsic Pontine...

United States, Canada
Monopteros Therapeutics Inc.

Recruiting

A Study of MPT-0118 in Subjects With Advanced or Metastatic Refractory Solid Tumors

Metastatic Cancer | Advanced Solid Tumor | Advanced Cancer | Solid Tumor, Adult | Refractory Cancer

United States
University Hospital, Montpellier

Recruiting

Deep Brain Stimulation of the Anterior Nucleus of the Thalamus in Intractable Epilepsy

Refractory Epilepsy

France
Boston Children's Hospital

Recruiting

Effects of Green Light Exposure on Epileptic Spikes in Patients With Refractory Epilepsy

Epilepsy | Epilepsy Intractable

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

A Study of TQ-B3525 on Tolerance and Pharmacokinetics

Relapsed or Refractory Lymphoma or Advanced Cancer

China
Immatics US, Inc.

Completed

TCR-engineered T Cells in Solid Tumors: IMA202-101 (ACTengine)

Cancer | Solid Tumor, Adult | Refractory Cancer | Recurrent Cancer

United States, Germany
University Hospital, Ghent

Completed

Acute and Long Term Effects of VNS on Memory in Patients With Refractory Epilepsy

Refractory Epilepsy

Belgium
Sierra Oncology, Inc.

Terminated

Momelotinib Combined With Capecitabine and Oxaliplatin in Adults With Relapsed/Refractory Metastatic Pancreatic Ductal Adenocarcinoma

Relapsed/Refractory Metastatic Pancreatic Ductal Adenocarcinoma

United States
M.D. Anderson Cancer Center

Recruiting

Cardiovascular Events Among Adults Patients With Relapsed or Refractory Aggressive B-Cell Lymphoma Treated With Standard of Care Chimeric Antigen Receptor T Cell Therapy

Recurrent Diffuse Large B-Cell Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent Aggressive B-Cell Non-Hodgkin Lymphoma | Recurrent High Grade B-Cell... and other conditions

United States
Shanghai General Hospital, Shanghai Jiao Tong University...

Recruiting

Venetoclax Plus IM2 Regimen for Relapsed and Refractory T Lymphoblastic Lymphoma/Leukemia

Refractory Lymphoma | Refractory Leukemia | Efficacy, Self | T-lymphoblastic Lymphoma | Safety | Relapsed Disease

China
National Cancer Institute (NCI)

Active, not recruiting

Lenalidomide and Ibrutinib in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Mantle Cell Lymphoma | Recurrent Follicular Lymphoma | Refractory Follicular Lymphoma | Refractory Marginal Zone Lymphoma | Recurrent Lymphoplasmacytic... and other conditions

United States, Canada
Xuanwu Hospital, Beijing

Recruiting

Application of tDCS Stimulation in Controlling Refractory Status Epilepticus (tDCS)

Refractory Status Epilepticus

China
Yale University

Recruiting

Feasibility Study: tDCS for Treatment of Refractory Status Epilepticus

Status Epilepticus | Refractory Status Epilepticus

United States
Marinus Pharmaceuticals

Withdrawn

To Evaluate the Efficacy, Safety, and Tolerability of Intravenous Ganaxolone Added to Standard of Care in Refractory Status Epilepticus (RSE)

Refractory Status Epilepticus

Spain, Switzerland, Germany, France, Austria, Italy, Belgium, United Kingdom, Czechia, Croatia, Finland, Lithuania, Israel, Hungary, Poland, Slovakia
Yi-Lun Wang

Completed

Ruxolitinib as add-on Therapy in Steroid-refractory Graft-vs-host Disease

Steroid Refractory GVHD

Taiwan
Immatics US, Inc.

Completed

Human Leukocyte Antigen Typing and Tumor Antigen Expression Profiling

Neoplasms | Adult Solid Tumor | Refractory Cancer | Recurrent Cancer

United States
University Hospital, Basel, Switzerland

Completed

Refractory Status Epilepticus Treatment: Quality and Efficacy of Coma Induction (RESET)

Status Epilepticus | Refractory Status Epilepticus

Switzerland
Seattle Children's Hospital
Aadi Bioscience, Inc.

Completed

ABI-009 (Nab-rapamycin) for Surgically-Refractory Epilepsy (RaSuRE)

Epilepsy Intractable

United States
University Hospital, Montpellier
Centre Hospitalier Universitaire de Nīmes; Institut du Cancer de Montpellier; Oncopole Toulouse

Completed

Intrathecal Analgesia Effects on Cancer Patients Discomfort Symptoms (IT-ESAS)

Refractory Cancer Pain | Intrathecal Analgesia

France
Cliniques universitaires Saint-Luc- Université...

Unknown

Added Value of Automated Electrical Source Localization (EPILOG PreOp®) to Presurgical Evaluation of Refractory Epilepsy (EPILOG)

Epilepsies, Partial

Belgium

Clinical Trials on CLL, Refractory

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Hungary

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations