Clinical Trials on CLN1 Disease

Total 376894 results

Universitätsklinikum Hamburg-Eppendorf

Recruiting

Natural History and Longitudinal Clinical Assessments in NCL / Batten Disease, the International DEM-CHILD Database

Batten Disease | Neuronal Ceroid Lipofuscinosis | CLN1 Disease | CLN2 Disease | CLN3 Disease | CLN4 Disease | CLN5 Disease | CLN6 Disease | CLN7 Disease | CLN8 Disease | CLN10 Disease | CLN11 Disease | CLN12 Disease | CLN13 Disease | CLN14 Disease

Germany
University of Rochester

Recruiting

Clinical and Neuropsychological Investigations in Batten Disease

Batten Disease | Neuronal Ceroid Lipofuscinosis | Neuronal Ceroid Lipofuscinosis CLN6 | Neuronal Ceroid Lipofuscinosis CLN3 | Neuronal Ceroid Lipofuscinosis CLN5 | Neuronal Ceroid Lipofuscinosis CLN1 | Neuronal Ceroid Lipofuscinosis CLN2 | Neuronal Ceroid Lipofuscinosis CLN7 | Neuronal Ceroid Lipofuscinosis... and other conditions

United States
BioMarin Pharmaceutical

Approved for marketing

A Multicenter, Multi-national Open-label Program to Provide BMN 190 to Patients Diagnosed With CLN2 Disease

CLN2 Disease

United Kingdom, United States, Germany, Italy
Benjamin Greenberg

Active, not recruiting

Study for the Treatment for CLN7 Disease (CLN7)

CLN7

United States
Amicus Therapeutics

Terminated

Natural History Study of Batten Disease

Batten Disease | Neuronal Ceroid Lipofuscinosis CLN6 | Neuronal Ceroid Lipofuscinosis CLN3

United States
Nadir Hastalıkları Araştırma Derneği

Recruiting

A Multicenter Selective Screening Study to Investigate the Frequency of Neuronal Ceroid Lipofuxinosis Type 2 (CLN2) (ENIGMA)

Neuronal Ceroid Lipofuxinosis Type2 (CLN2)

Turkey
Rajavithi Hospital

Withdrawn

Efficacy of Topical 95% TCA in the Treatment of CIN 1 or Less After Low-grade Abnormality of Screening Test

CIN1 | Trichloroacetic Acid

Thailand
Eunice Kennedy Shriver National Institute of Child...

Completed

Optic-to-Audio Device in a Pediatric Cohort With CLN3-related Conditions or Low Vision

Low Vision | CLN3-related Disorders

United States
BioMarin Pharmaceutical

Completed

A Safety, Tolerability, and Efficacy Study of Intracerebroventricular BMN 190 in Pediatric Patients < 18 Years of Age With CLN2 Disease

Batten Disease | CLN2 Disease | Late-Infantile Neuronal Ceroid Lipofuscinosis Type 2 | Jansky-Bielschowsky Disease | CLN2 Disorder

United States, Germany, Italy, United Kingdom
BioMarin Pharmaceutical

Completed

An Extension Study to Evaluate the Long-Term Efficacy and Safety of BMN 190 in Patients With CLN2 Disease

Batten Disease | CLN2 Disease | Late-Infantile Neuronal Ceroid Lipofuscinosis Type 2 | Jansky-Bielschowsky Disease | CLN2 Disorder

United States, Germany, Italy, United Kingdom
PDS Biotechnology Corp.

Completed

An Open-Label, Phase I, Escalating Dose Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of PDS0101

High-risk HPV Infection and Biopsy-proven CIN1

United States
Barinthus Biotherapeutics

Completed

Prime-boost Vaccine Study in Women With Low-grade Cervical HPV Lesions

HPV Infection | CIN1

Belgium, United Kingdom, Estonia
The University of Texas Health Science Center,...

Completed

Phase II Evaluation of AHCC for the Eradication of HPV Infections (AHCC4HPV)

Human Papilloma Virus | Dysplasia | CIN1 | CIN2

United States
Amicus Therapeutics

Active, not recruiting

Long-Term Follow Up of CLN6 Batten Disease Subjects Following Gene Transfer

Batten Disease | CLN6

United States
Amicus Therapeutics

Active, not recruiting

Gene Therapy for Children With CLN3 Batten Disease

Batten Disease | CLN3

United States
Emily de los Reyes

Recruiting

Natural History of Neuronal Ceroid Lipofuscinosis, Batten's CLN6 Diseae (Batten'sCLN6)

Batten Disease | CLN6

United States
Jessica Scherr
BioMarin Pharmaceutical

Enrolling by invitation

Examining Developmental Outcomes of Children Diagnosed With CLN2 Disease

Batten Disease | Neuronal Ceroid-Lipofuscinoses | CLN2

United States
Neurogene Inc.

Recruiting

Gene Therapy Study for Children With CLN5 Batten Disease (CLN5-200)

Neuronal Ceroid Lipofuscinosis CLN5

United States, United Kingdom
Eunice Kennedy Shriver National Institute of Child...

Recruiting

Investigations of Juvenile Neuronal Ceroid Lipofuscinosis

Batten Disease | Juvenile Neuronal Ceroid Lipofuscinosis (CLN3)

United States
REGENXBIO Inc.

Withdrawn

An Observational Study in Children With CLN2 Batten Disease

Neuronal Ceroid Lipofuscinosis Type 2 (CLN2)
BioMarin Pharmaceutical

Completed

A Phase 1/2 Open-Label Dose-Escalation Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of Intracerebroventricular BMN 190 in Patients With Late-Infantile Neuronal Ceroid Lipofuscinosis (CLN2) Disease

Batten Disease | CLN2 Disease | Late-Infantile Neuronal Ceroid Lipofuscinosis Type 2 | Jansky-Bielschowsky Disease

United States, Italy, Germany, United Kingdom
REGENXBIO Inc.

Withdrawn

A Retrospective, Natural History Study in Children With CLN2

Late-infantile Neuronal Ceroid Lipofuscinosis Type 2 (CLN2)
Catalysis SL
Atika Pharma S.L.

Recruiting

Evaluation Of The Efficacy Of The Combination Of GLIZIGEN® Oral Solution 1/Day And Vaginal Gel 1/Night For 2 Months In Patients With Cervical Intraepithelial Neoplasia Grade 1 (LSIL/CIN-1) Caused By High-Risk Human Papillomavirus (HPV-AR)

Papilloma Viral Infection | CIN1 | LSIL, Low Grade Squamous Intraepithelial Lesion

Spain
Shanghai Bovax Biotechnology Co., Ltd.

Terminated

A Phase Ⅲ Study to Evaluate the Efficacy, Immunogenicity, Safety of Quadrivalent HPV Recombinant Vaccine in Chinese Healthy Females

Cervical Cancer | CIN1 | CIN2 | CIN3 | Genital Wart | AIS | Vain I | Vain III | Vin I | Vin II | Vin III | VAIN - Vaginal Intraepithelial Neoplasia 2

China
Children's Hospital of Orange County

Active, not recruiting

Longitudinal Assessment of Atypical Tripeptidyl Peptidase 1 Enzyme Deficiency Patients

Neuronal Ceroid-Lipofuscinoses | Neuronal Ceroid Lipofuscinosis CLN2 | Spinocerebellar Ataxia, Autosomal Recessive 7

United States
Shanghai Bovax Biotechnology Co., Ltd.
Chongqing Bovax Biopharmaceutical Co., Ltd.

Completed

Evaluate the Immunogenicity and Safety of 4-valent and 9-valent HPV Recombinant Vaccine in Chinese Healthy Females

Cervical Cancer | Vulvar Cancer | Vaginal Cancer | CIN1 | CIN2 | CIN3 | VaIN1 | VaIN2 | VaIN3 | Genital Wart | VIN 1 | VIN 2 | VIN 3 | AIS

China
Shanghai Bovax Biotechnology Co., Ltd.
Chongqing Bovax Biopharmaceutical Co., Ltd.

Completed

Evaluate the Immunogenicity and Safety of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females

Cervical Cancer | Vulvar Cancer | Vaginal Cancer | CIN1 | CIN2 | CIN3 | VaIN1 | VaIN2 | VaIN3 | Genital Wart | VIN 1 | VIN 2 | VIN 3 | AIS | HPV Infections

China
Shanghai Bovax Biotechnology Co., Ltd.
Chongqing Bovax Biopharmaceutical Co., Ltd.

Completed

Evaluate the Safety and Primary Immunogenicity of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females

Vulvar Cancer | Vaginal Cancer | CIN1 | CIN2 | VaIN1 | VaIN2 | VaIN3 | Genital Wart | AIS | Invasive Carcinoma | Cervical Cancers | CIN 3 | Vin III | Mild Dysplasia of Vulva | Moderate Dysplasia of Vulva

China
Shanghai Bovax Biotechnology Co., Ltd.
Chongqing Bovax Biopharmaceutical Co., Ltd.

Recruiting

Immunogenicity and Safety of Quadrivalent HPV Vaccine in Healthy Chinese Female Subjects Aged 9 to 19 Years

Vaginal Cancer | Cervical Cancer Stage IIa | CIN1 | CIN2 | CIN3 | Genital Wart | HPV Infections

China
Shanghai Bovax Biotechnology Co., Ltd.
Chongqing Bovax Biopharmaceutical Co., Ltd.

Recruiting

Immunobridging Study of 9-valent Human Papillomavirus Recombinant Vaccine in Chinese Females Aged 9 to 19 Years

Cervical Cancer | Vulvar Cancer | Vaginal Cancer | CIN1 | CIN2 | VaIN1 | VaIN2 | VaIN3 | Genital Wart | VIN 1 | VIN 2 | VIN 3 | AIS | HPV Infections | CIN 3

China
Shanghai Bovax Biotechnology Co., Ltd.

Recruiting

Evaluate the Efficacy, Immunogenicity and Safety of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females

Cervical Cancer | Vulvar Cancer | Vaginal Cancer | CIN1 | CIN2 | CIN3 | VaIN1 | VaIN2 | VaIN3 | Genital Wart | VIN 1 | VIN 2 | VIN 3 | AIS

China
Shanghai Bovax Biotechnology Co., Ltd.

Recruiting

Immune Persistence After the Whole Vaccination Shcedule With Recombination Quadrivalent HPV Vaccine

Vaginal Cancer | Cervical Cancer Stage IIa | CIN1 | CIN2 | CIN3 | Genital Wart | HPV Infections

China
Gangnam Severance Hospital

Recruiting

Prevalence of Marginal Ulcer After PPPD and Preventive Effect of Proton Pump Inhibitor in Korea: A Prospective Multicenter Study

Pancretic Dissease (Benign/Malignancy) | BIle Duct Diseae(Benign/Malignancy) | Ampulla of Vater Disease (Benign/Malignancy)

Korea, Republic of
University of Michigan
National Institutes of Health (NIH); National Institute of Dental and Craniofacial...

Completed

The Importance of Periostin in Periodontal Health and Disease

Periodontal Disease | Non-diseased Patients

United States
Yonsei University

Active, not recruiting

Low-Density Lipoprotein Cholesterol-targeting Statin Therapy Versus the Intensity-based Statin Therapy in Patients With Coronary Artery Disease (LODESTAR)

Coronary Artery Diseasse

Korea, Republic of
Eisai Co., Ltd.

Completed

Post-marketing Surveillance of Donepezil Hydrochloride Investigation of the Safety and Effectiveness of Combination Therapy of Donepezil Hydrochloride and Memantine Hydrochloride in Patients With Alzheimer's Disease

Alzheimer's Desease

Japan
McMaster Children's Hospital
St. Justine's Hospital

Completed

PediCRaFT: Pediatric Crohn's Disease Fecal Transplant Trial (PediCRaFT)

Inflammatory Bowel Diseases | Crohn Disease | Colitis | Pediatric Crohns Disease

Canada
First Affiliated Hospital of Wenzhou Medical University

Completed

Tongue Image Database and Diagnostic Model for Digestive Tract Disease Diagnosis

Liver Diseases | Small Bowel Disease | Colorectal Disease | Gastric Diseases | Digestive Tract Diseases

China
Academisch Medisch Centrum - Universiteit van Amsterdam...
Celltrion

Recruiting

inDuctIon tREatment With subCuTaneous Infliximab for Crohn's Disease (DIRECTCD)

Bowel Disease | Inflammatory Disease | Disease Crohn

Netherlands
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Raynaud's Treatment Study (RTS)

Heart Diseases | Cardiovascular Diseases | Vascular Diseases | Raynaud's Disease
The Second Hospital of Nanjing Medical University
Air Force Military Medical University, China

Recruiting

Standardized Fecal Microbiota Transplantation for Crohn&Apos;s Diseases

Inflammatory Bowel Disease | Crohn's Diseases

China
Facet Biotech

Completed

A Humanized Anti-Interferon-γ Monoclonal Antibody (HuZAF) for Moderate to Severe Crohn's Disease

Crohn's Disease | Colitis | Digestive System Disease | Gastrointestinal Disease | Intestinal Disease

United States, Canada
Central Hospital, Nancy, France
Institut Régional de Médecine Physique et de Réadaptation

Unknown

Interest of Hydrophysiotherapy Care in Parkinson Disease's Motor and Non-motor Symptoms (THERMAPARK)

Interest of Hydrophysiotherapy Care in Parkinson Disease's Non-motor Symptoms
Klinikum Westbrandenburg GmbH

Unknown

TOPIT; Trough Level Optimized Pediatric Inflammatory Bowel Disease Therapy: A Multicenter Study Comparing Effectiveness of Trough Level Optimized Infliximab Maintenance Therapy With Standard Dosing Regimen of Pediatric Patients With Crohn's Disease (TOPIT)

Pediatric Crohns Disease
University of Bern
Merck Sharp & Dohme LLC; University Hospital, Basel, Switzerland; University... and other collaborators

Completed

Significance of Ficolin 2 in the Determination of Serological Activity in Chronic Inflammatory Bowel Disease

Crohn Disease

Switzerland
Children's Hospital Los Angeles

Completed

FMT in Pediatric Crohn's Disease (FMTPCD)

Crohn Disease | Pediatric Crohns Disease

United States
Ryazan State Medical University

Completed

Chronic Obstructive Pulmonary Disease in Combination With Atherosclerosis (Clinical and Biochemical Study)

Chronic Obstructive Pulmonary Disease | Peripheral Artery Disease

Russian Federation
Direct Biologics, LLC

Recruiting

Study of ExoFlo for the Treatment of Medically Refractory Crohn's Disease

Inflammatory Bowel Diseases | Crohn Disease

United States
First Affiliated Hospital of Harbin Medical University

Unknown

"Air Assisted"Water Injection Colonoscopy in Experienced Endoscopists

Colon Disease; | Rectal Disease

China
Fondazione IRCCS Policlinico San Matteo di Pavia
University of Pavia

Recruiting

Calcific Aortic Valve Disease:the Role of Bacteria as Trigger of a Chronic Inflammation

Calcific Aortic Valve Diasease

Italy

Clinical Trials on CLN1 Disease

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