Clinical Trials on COPD, One Lung Ventilation in South Africa

Total 188 results

Nuvaira, Inc.

Completed

Innovative Pulmonary Solutions (IPS) System for Targeted Lung Denervation (IPS-I)

Chronic Obstructive Pulmonary Disease (COPD)

Netherlands, South Africa
Elpen Pharmaceutical Co. Inc.

Recruiting

Clinical Study for the Effectiveness of Roflumilast Treatment in COPD Greek Patients Based on Standard Clinical Practice. (ARGO)

Copd | COPD Exacerbation

Greece
Sanofi

Completed

Immunogenicity and Safety of Pentaxim in South African Infants

Pertussis | Tetanus | Diphtheria | Poliomyelitis | Haemophilus Infections

South Africa
Sanofi

Completed

Antibody Persistence in Healthy Children After Primary and Booster DTaP-IPV-Hep B-PRP-T Vaccine or Control Vaccine

Hepatitis B | Whooping Cough | Tetanus | Diphtheria | Poliomyelitis

South Africa
AstraZeneca

Completed

The HERO-study: Effects of Roflumilast in Patients With COPD (Chronic Obstructive Pulmonary Disease) (BY217/M2-121)

Chronic Obstructive Pulmonary Disease, COPD

France, Poland, South Africa, Spain, United States, Canada, United Kingdom
AstraZeneca

Completed

Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease. Ratio-Study. (BY217/M2-112)

Chronic Obstructive Pulmonary Disease | COPD

Austria, France, Hungary, Italy, Poland, Portugal, Russian Federation, South Africa, Spain, Canada, United Kingdom, Australia, Netherlands, Switzerland
Sanofi Pasteur, a Sanofi Company

Completed

Study to Evaluate the Immune Response After Booster Vaccination With Tdap-IPV Vaccine (Against Tetanus, Diphtheria, Pertussis and Poliomyelitis) in Children Who Received Different Pertussis Primary Vaccine Regimens in Republic of South Africa

Pertussis Immunisation | Diphtheria Immunisation | Tetanus Immunisation | Poliomyelitis Vaccine

South Africa
University of Athens
Academy of Athens

Completed

Clinical and Biological Markers in Acute Respiratory Failure

Acute Respiratory Distress Syndrome | Ventilator-Associated Pneumonia

Greece
Novartis

Completed

A Crossover Study to Determine the Effect on Lung Function of Indacaterol in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD), Using Tiotropium as an Active Control

Chronic Obstructive Pulmonary Disease (COPD)

Spain, Germany, South Africa, Australia, Poland, New Zealand, Netherlands
Dey

Completed

Study to Evaluate the Safety of Long-Term Use of Perforomist® (Formoterol Fumarate)

COPD

United States
Pearl Therapeutics, Inc.

Withdrawn

Efficacy and Safety of Two Doses of Formoterol Fumarate MDI (PT005) in Patients With Stable Chronic Obstructive Pulmonary Disease (COPD), Compared to Foradil® Aerolizer® as an Active Control

COPD

United States
Sunovion Respiratory Development Inc.

Completed

A Dose-Range Finding Study of SUN-101 in Subjects With Moderate to Severe COPD (GOLDEN 6)

COPD

United States
Pharmaxis

Withdrawn

A Pilot Safety Study of Inhaled Dry Powder Mannitol in Acute Exacerbations of COPD

COPD | Exacerbation

Australia
Raffaele Dellaca
Baylor College of Medicine; Ospedale di Circolo e Fondazione Macchi, Varese; Fondazione... and other collaborators

Unknown

Monitoring Chronic Obstructive Pulmonary Disease Patients at Home by a Forced Oscillation Technique Device

COPD

Australia, Italy
The Queen Elizabeth Hospital

Completed

Trial of Portable Oxygen Cylinders Versus Battery Powered Portable Oxygen Concentrators

COPD

Australia
Sunovion

Completed

Study of Arformoterol Tartrate Inhalation Solution and Racemic Formoterol in Subjects With Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD)

COPD

United States
Medical University of South Carolina

Terminated

Feasibility of Music Therapy for Spontaneous Breathing Trials

Intubation | Mechanical Ventilation | Music Therapy | Spontaneous Breathing Trial

United States
Mylan Inc.
Theravance Biopharma

Completed

A 28-Day Parallel Group Study of TD-4208 in Chronic Obstructive Pulmonary Disease (COPD)

COPD

United States
Macquarie University, Australia

Completed

The Use of Aeriseal ® in the Management of Collateral Ventilation Positive COPD Patients Undergoing ELVR Utilizing Endobronchial Valves.

Chronic Obstructive Pulmonary Disease (COPD)

Australia
Soroka University Medical Center

Recruiting

Diagnosing Obstructive Lung Disease With Point of Care Ultrasound

Lung Diseases, Obstructive | Pulmonary Disease, Chronic Obstructive | Asthma | COPD

Israel
Pearl Therapeutics, Inc.

Completed

Glycopyrronium and Formoterol Fumarate (GFF) Metered Dose Inhaler (MDI) Dose Indicator Study in Adults With Moderate to Very Severe COPD

COPD

United States
Brno University Hospital
Masaryk University

Withdrawn

Mouth-to-mouth Ventilation Efficiency Through Breathable Self-sterilizing Respirator During BLS in COVID-19 Pandemic (MOVE) (MOVE)

Basic Life Support Ventilation

Czechia
The George Institute
Sunnybrook Health Sciences Centre; Imperial College London

Completed

Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients (SuDDICU)

Sepsis | Critical Illness | Septic Shock | Ventilator Associated Pneumonia

Australia, Canada, United Kingdom
Mylan Inc.
Theravance Biopharma

Completed

A 52-Week Parallel Group Safety Study of TD-4208 in Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Mylan Inc.
Theravance Biopharma

Completed

Efficacy Study of Nebulized TD-4208 for Chronic Obstructive Pulmonary Disease (COPD) (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Pearl Therapeutics, Inc.

Completed

Efficacy and Safety Study of Two Dose Levels of AZD2115 in Subjects With Moderate to Severe COPD

Chronic Obstructive Pulmonary Disease (COPD)

United States
Novartis
Schering-Plough

Completed

A Dose Ranging Trial of 4 Doses of Indacaterol Delivered Via the TWISTHALER® Device in Patients With Chronic Obstructive Pulmonary Disease (COPD)

COPD

France, Germany, Belgium, Italy, Turkey, Hungary, Argentina, Peru, United Kingdom, South Africa, Latvia, Lithuania, Romania, Chile, Ireland, Norway, Poland
AstraZeneca

Completed

Pharmacokinetic, Safety and Tolerability Study of Aclidinium/Formoterol Fixed Dose Combination and Formoterol in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Phargentis SA

Completed

Bioequivalence Study of Tiotropium Bromide Inhalation Powder

COPD

United States, India, Switzerland
AstraZeneca

Completed

Latin American Study of 24-hs Symptoms in Chronic Obstructive Pulmonary Disease (COPD) Patients; LASSYC Study (LASSYC)

Stable COPD Patients

Mexico, Chile, Argentina, Colombia, Costa Rica, Uruguay
University of South Carolina
Brown University

Recruiting

Breathe Easier II: A Dyad-based Multiple Behavior Intervention (BE)

Quality of Life | Stress | COPD | Lung Cancer, Nonsmall Cell | Physical Inactivity | Self-Management

United States
Aquinox Pharmaceuticals (Canada) Inc.

Completed

Efficacy and Safety of AQX-1125 in Unstable COPD (FLAGSHIP)

COPD

United States, New Zealand, Poland, Australia, Denmark, Finland, Hungary, Sweden
Sunovion

Completed

A Dose Ranging Study of Arformoterol Given Once Daily Compared to Arformoterol Given Twice Daily in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

COPD

United States
Alkermes, Inc.

Completed

ALK27-001: A Study of Trospium Inhalation Powder (TrIP)Administered to Subjects With COPD

Chronic Obstructive Pulmonary Disease (COPD)

United States
Nephron Pharmaceuticals Corporation
Rho, Inc.

Completed

Tiotropium Bromide Inhalation Solution in Subjects With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease (COPD)

United States
Apreo Health, Inc.

Recruiting

First in Human Study to Assess an Implant to Treat Severe Emphysema (BREATHE-1)

Emphysema or COPD

Australia
AstraZeneca

Completed

OPUS Study: Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease (BY217/M2-111)

Chronic Obstructive Pulmonary Disease | COPD

United States, France, Poland, South Africa, Canada, Germany
AstraZeneca

Completed

Phase IV O2 Consumption Study in COPD Patients.

Chronic Obstructive Pulmonary Disease (COPD)

United States
Medical University of South Carolina
South Carolina Spinal Cord Injury Research Fund

Recruiting

CEUS For Intraoperative Spinal Cord Injury

Spinal Cord Diseases | Spinal Stenosis | Spinal Cord Injuries | Spine Degeneration | Spinal Cord Compression | Spine Disease | Spinal Injury

United States
AstraZeneca
Iqvia Pty Ltd; Premier Inc.

Withdrawn

IKANOS: Breztri Maintenance Versus Any Non-Triple Inhaled Therapy After Hospitalization for a COPD Exacerbation in the US (IKANOS)

COPD

United States
AstraZeneca

Completed

A Phase IIa Study to Investigate the Efficacy and Safety of AZD7624 in Chronic Obstructive Pulmonary Disease (COPD) Patients While on Maintenance Therapy

Chronic Obstructive Pulmonary Disease COPD

United States, Netherlands, Argentina, South Africa, Chile, Peru
Novartis Pharmaceuticals

Completed

Efficacy and Safety of QMF149 vs. Salmeterol Xinafoate/Fluticasone Propionate in Patients With Chronic Obstructive Pulmonary Disease (COPD)

COPD

Spain, Germany, Belgium, Poland, South Africa, Australia, Greece, Israel, Sweden, Hong Kong, Thailand, Bulgaria, Singapore, Denmark, Finland, Hungary, Romania, Malaysia
Australian and New Zealand Intensive Care Research...
National Health and Medical Research Council, Australia; Medical Research Institute... and other collaborators

Enrolling by invitation

The TEAM Long-Term Cohort Study (A Sub-study of TEAM(III))

Critically Ill | Mechanical Ventilation | Long Term Outcome

Australia
GlaxoSmithKline

Completed

Pharmacokinetic and Pharmacodynamic (PK and PD) Study of Fluticasone Propionate and Salmeterol Combination Product Delivered in a Capsule-based Inhaler and in a Multi-dose Dry Powder Inhaler in Moderate Asthma Patients and Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) Patients.

Asthma

Australia, New Zealand
Guy's and St Thomas' NHS Foundation Trust
King's College London; University of Nottingham; Imperial College London; University... and other collaborators

Not yet recruiting

Supported Rescue Packs Post-discharge in Chronic Obstructive Pulmonary Disease (RAPID)

COPD | COPD Exacerbation

United Kingdom
Dey

Completed

A Study Characterizing Pharmacodynamic Profiles in Subjects With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease (COPD)

United States
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Recruiting

MUlti-nuclear MR Imaging Investigation of Respiratory Disease-associated CHanges in Lung Physiology (MURDOCH)

Covid19 | Asthma | COPD | Long COVID

United Kingdom
Woolcock Institute of Medical Research

Recruiting

Biomarkers of Dementia in Chronic Sleep and Breathing Disorders (ORACLE)

OSA | COPD | Overlap Syndrome

Australia
Verona Pharma plc
Iqvia Pty Ltd; LGC Limited

Completed

Study Investigating the Effect of 4 Doses of RPL554 Given in Addition to Tiotropium to Patients With COPD

COPD

United States
Sunovion Respiratory Development Inc.

Completed

Efficacy and Safety Trial of 12 Weeks of Treatment With Nebulized SUN-101 in Patients With COPD (GOLDEN-3)

COPD

United States

Clinical Trials on COPD, One Lung Ventilation in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Kosovo

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations