Clinical Trials on Cancer Rectum

Total 53739 results

National Cancer Institute (NCI)

Completed

Atorvastatin Calcium, Oligofructose-Enriched Inulin, or Sulindac in Preventing Cancer in Patients at Increased Risk of Developing Colorectal Neoplasia

Rectal Cancer | Colon Cancer | Precancerous Condition

United States
CENTOGENE GmbH Rostock

Completed

Peptide-based Immunization for Colon- and and Pancreas-carcinoma (PICOP-GLOBAL)

Pancreatic Neoplasms | Pancreatic Cancer | Pancreatic Adenocarcinoma | Rectal Cancer | Rectal Neoplasms | Colon Cancer | Pancreas Cancer | Colo-rectal Cancer | Rectal Adenocarcinoma | Colon Neoplasm | Rectal Tumors | Colon Adenocarcinoma

Pakistan
Imperial College London

Recruiting

Circulating Tumour DNA (ctDNA) in Patients With Colorectal Cancer and the Relationship to Imaging Features of Extramural Venous Invasion (ctDNA)

Cancer | Rectal Cancer

United Kingdom
National Cancer Institute (NCI)

Completed

Aspirin in Preventing Colorectal Cancer in Patients at Increased Risk of Colorectal Cancer

Rectal Cancer | Colon Cancer | Precancerous Condition

United States
Centre Hospitalier Universitaire de Saint Etienne

Recruiting

Performance of Spectral CT-scan in Patients With Metastatic Colorectal Cancer: a Prospective Multicentre Study

Colo-rectal Cancer

France
Lithuanian University of Health Sciences

Recruiting

Neoadjuvant Therapy vs Standard Therapy in Locally Advanced Rectal Cancer (RECTUM2015)

Neoadjuvant Therapy in Rectal Cancer, Radiotherapy, FOLFOX

Lithuania
Check-Cap Ltd.

Completed

Motility of the Check-cap's MD1 Colon Capsule in Subjects Following Colon Rectal Cancer Screening by Colonoscopy

Colo-rectal Cancer

Israel
Abramson Cancer Center of the University of Pennsylvania

Withdrawn

DCE-MRI PET Bevacizumab Study in Rectal Cancer

Rectal Cancer Patients
US Oncology Research
Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma

Terminated

Study of Colorectal Cancer Patients (Stage IIIC) With Either Regorafenib or Standard of Care (No Treatment) After Adjuvant FOLFOX

Colorectal Neoplasms | Adenocarcinoma of the Rectum | Adenocarcinoma of the Colon

United States
Assistance Publique - Hôpitaux de Paris

Completed

Mechanical Bowel Preparation and Oral Antibiotics Before Rectal Cancer Surgery (PREPACOL2)

Rectal Cancer Surgery

France
Sir Mortimer B. Davis - Jewish General Hospital
Sanofi

Completed

A Study on the Timing of FOLFOX for Patients With Operable, Node Positive Rectal Cancer

Operable T2-3N+M0 Rectal Cancer (Stage III)

Canada
Fudan University

Unknown

The Combination of Immunotherapy and Neoadjuvant Chemoradiotherapy in MSI-H Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Complete Versus Partial Preservation of Denonvilliers' Fascia on Urogenital Function in Locally Advanced Rectal Cancer

Rectal Cancer | Advanced Cancer

China
Case Comprehensive Cancer Center

Withdrawn

Circulating Tumor DNA to Monitor the Efficacy of Total Neoadjuvant Therapy for Rectal Cancer

Colorectal Cancer | Rectal Cancer

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Canadian Cancer Trials Group

Active, not recruiting

PROSPECT: Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing Surgery

Colorectal Cancer

United States, Canada, Israel, Switzerland
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Radiation Therapy and Fluorouracil With or Without Combination Chemotherapy Followed by Surgery in Treating Patients With Stage II or Stage III Rectal Cancer

Colorectal Cancer

United States, Canada
Eisai Inc.
PharmaBio Development Inc.

Terminated

Irinotecan Plus E7820 Versus FOLFIRI in Second-Line Therapy in Patients With Locally Advanced or Metastatic Colon or Rectal Cancer

Rectal Cancer | Colon Cancer

Argentina, Russian Federation, United States, Australia, Brazil, Ukraine
Novadaq Technologies ULC, now a part of Stryker

Terminated

A Study Assessing Perfusion Outcomes With PINPOINT® Near Infrared Fluorescence Imaging in Low Anterior Resection (PILLAR III)

Rectal Cancer | Rectosigmoid Cancer

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Laparoscopic-Assisted Resection or Open Resection in Treating Patients With Rectal Cancer

Colorectal Cancer

United States, Canada
Sherief Abd-Elsalam
Tanta University

Unknown

Genetic Variants of Selected Genes in Colo-Rectal Cancer Patients.

Cancer Colon

Egypt
Hoffmann-La Roche

Completed

A Study of Xeloda (Capecitabine) Plus Radiotherapy in Participants With Locally Advanced Rectal Cancer

Colorectal Cancer

Slovakia
Hoffmann-La Roche

Completed

A Study of Avastin (Bevacizumab) Plus Xeloda (Capecitabine) in Patients With Locally Advanced Rectal Cancer.

Colorectal Cancer

Italy
Southwest Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; NCIC Clinical... and other collaborators

Completed

SWOG-9304 Chemotherapy Plus Radiation Therapy in Treating Patients With Rectal Cancer That Has Been Surgically Removed

Colorectal Cancer

United States, Canada, South Africa
Centre Hospitalier Universitaire Vaudois

Unknown

Radiation Therapy, Irinotecan, and Cetuximab in Treating Patients Who Are Undergoing Surgery for Stage III or Stage IV Rectal Cancer

Colorectal Cancer

Switzerland
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Intensity-Modulated Radiation Therapy With Incorporated Boost and Capecitabine Before Surgery in Treating Patients With Locally Advanced Rectal Cancer

Colorectal Cancer

United States
Hebei Medical University Fourth Hospital

Recruiting

Short-course Radiotherapy Followed by Tislelizumab + CapeOX in the Treatment for Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
University of Jordan
Slovak Academy of Sciences; Al-Quds University

Unknown

Effectiveness of Vitamin E and Hydrogen-Rich Water on Radiation Therapy-Induced Adverse In Patients With Rectal Cancer

Radiation-induced Injuries in Patients With Rectal Cancer

Palestinian Territory, occupied
Instituto Nacional de Cancer, Brazil

Terminated

Induction Chemotherapy Plus Chemoradiotherapy With or Without Aspirin in High Risk Rectal Cancer (ICAR)

Chemoradiation | Rectal Cancer, Adenocarcinoma | Locally Advanced Malignant Neoplasm

Brazil
Oslo University Hospital

Terminated

LOTCOL Study: Local Treatment of Colo-rectal Liver Met (LOTCOL)

Metastatic Colo-rectal Cancer

Norway
Institute of Oncology Ljubljana

Completed

Capecitabine as Radiosensitising Agent in Neoadjuvant Treatment of Locally Advanced Resectable Rectal Cancer

Resectable Rectal Cancer Clinical Stage II and III

Slovenia
Corregene Biotechnology Co., Ltd

Recruiting

CRTE7A2-01 TCR-T Cell for HPV-16 Positive Advanced Cervical, Anal, or Head and Neck Cancers

Cervical Cancer | Anal Cancer | Head and Neck Cancers

China
Universitaire Ziekenhuizen KU Leuven

Completed

Neoadjuvant Bevacizumab, Capecitabine and Radiation Therapy With or Without Oxaliplatin Locally Advanced Rectal Cancer (AXEBEAM)

Locally Advanced Rectal Cancer

Belgium
Assistance Publique - Hôpitaux de Paris

Completed

Rectal Cancer Surgery Without Mechanical Bowel Preparation (PREPACOL)

Patients With Rectal Cancer

France
AIO-Studien-gGmbH
Sanofi; Institut für Klinisch-Onkologische Forschung (IKF) Frankfurt

Completed

mFOLFOX6 vs. mFOLFOX6 + Aflibercept as Neoadjuvant Treatment in MRI-defined T3-rectal Cancer

Rectal Cancer | Rectosigmoid Cancer

Germany
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Radiation Therapy and Chemotherapy Followed by Surgery and Combination Chemotherapy in Treating Patients With Rectal Cancer

Colorectal Cancer

United States
Swiss Group for Clinical Cancer Research

Completed

External-Beam Radiation Therapy, Capecitabine, and Sorafenib in Treating Patients With Locally Advanced Rectal Cancer

Colorectal Cancer

Switzerland, Hungary
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Combination Chemotherapy and Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Locally Advanced Rectal Cancer

Colorectal Cancer

United States, Canada
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0713: Oxaliplatin, Capecitabine, Cetuximab, and RT Followed By Surgery in Pts W/Stage II or III Rectal Cancer

Colorectal Cancer

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Capecitabine, Oxaliplatin, and Radiation Therapy in Treating Patients Who Are Undergoing Surgery for Stage I Rectal Cancer

Colorectal Cancer

United States
Beth Israel Medical Center

Completed

Neo-adjuvant Chemoradiation With Oxaliplatin/5-FU in Rectal Cancer

Colorectal Cancer

United States
Hoffmann-La Roche
Sanofi

Completed

An Observational Study of Xeloda (Capecitabine) and Oxaliplatin Prior and Concurrent To Preoperative Pelvic Radiotherapy in Patients With Locally Advanced Rectal Cancer

Colorectal Cancer

Switzerland
Cardiff University
Cancer Research UK

Completed

Oxaliplatin, Leucovorin, and Fluorouracil Before and After Radiation Therapy and Surgery in Treating Patients With Rectal Cancer That Can Be Removed by Surgery (COPERNICUS)

Colorectal Cancer

United Kingdom
European Organisation for Research and Treatment...

Completed

Radiation Therapy, Surgery, and Chemotherapy in Treating Patients With Rectal Cancer That Can Be Surgically Removed

Colorectal Cancer

France, Belgium, Netherlands, Switzerland, Israel, Serbia, Spain, Poland, Turkey, Germany
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI); Genentech, Inc.

Completed

Combination Chemotherapy and Bevacizumab With or Without Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer

Colorectal Cancer

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

PET and CT Scans in Patients With Locally Advanced Primary Rectal Cancer That Can Be Removed During Surgery

Colorectal Cancer

United States
Loma Linda Oncology Medical Group, Inc.

Unknown

Capecitabine, Panitumumab, and Radiation Therapy With or Without Irinotecan Hydrochloride in Treating Patients Undergoing Surgery for Localized Rectal Cancer

Colorectal Cancer

United States
Medical Research Council
NCIC Clinical Trials Group

Completed

Radiation Therapy Before Surgery Compared With Chemotherapy Plus Radiation After Surgery in Treating Patients With Rectal Cancer That Can Be Surgically Removed

Colorectal Cancer

Canada, United Kingdom
National Medical Research Council (NMRC), Singapore

Unknown

Comparison of Two Types of Surgery in Treating Patients With Rectal Cancer

Colorectal Cancer

China, Singapore
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Completed

Celecoxib, Fluorouracil, and Radiation Therapy in Treating Patients With Stage II or Stage III Rectal Cancer That Can Be Removed By Surgery

Colorectal Cancer

United States
Royal Marsden NHS Foundation Trust

Unknown

Oxaliplatin, Capecitabine, and Radiation Therapy With or Without Cetuximab in Treating Patients Undergoing Surgery for High-Risk Rectal Cancer (EXPERT-C)

Colorectal Cancer

Spain, United Kingdom, Sweden

Clinical Trials on Cancer Rectum

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Saudi Arabia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations