Clinical Trials on Candidates for BRCA 1/2 Genetic Testing
Total 845 results
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Abramson Cancer Center of the University of PennsylvaniaCompletedCandidates for BRCA 1/2 Genetic TestingUnited States
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Memorial Sloan Kettering Cancer CenterPhenogen SciencesRecruitingGenetic Testing | BRCA1/2United States
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University of MichiganCompletedWomen With BRCA 1 or BRCA 2 Mutation | Non-tested Female Family MembersUnited States
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University of WashingtonAbbVieNo longer availableTriple-Negative Breast Cancer | Metastatic Breast Cancer With BRCA 1 or BRCA 2 Genetic MutationUnited States
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PfizerMedivation, Inc.; Myriad Genetic Laboratories, Inc.TerminatedBreast Neoplasms | BRCA 1 Gene Mutation | BRCA 2 Gene MutationUnited States, Spain, United Kingdom, Germany, France
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PfizerMedivation, Inc.CompletedBreast Neoplasms | BRCA 1 Gene Mutation | BRCA 2 Gene MutationKorea, Republic of, United States, Australia, Spain, Belgium, France, Ireland, Taiwan, Poland, Germany, Israel, Brazil, United Kingdom, Italy, Russian Federation, Ukraine
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PfizerTerminatedLocally Advanced or Metastatic Solid Tumors | Genes, BRCA 1United States, Belgium, Spain, Denmark, Japan, France, Italy, Netherlands, United Kingdom
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AstraZenecaMerck Sharp & Dohme LLC; Myriad Genetic Laboratories, Inc.Active, not recruitingBreast Cancer Metastatic | BRCA 1 Gene Mutation | BRCA 2 Gene MutationItaly, Spain, United States, Czechia, Romania, France, Korea, Republic of, United Kingdom, Hungary, Japan, Peru, Poland, Russian Federation, Turkey, China, Taiwan, Bulgaria, Switzerland, Mexico
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Jiangxi Qingfeng Pharmaceutical Co. Ltd.UnknownBreast Cancer Metastatic | BRCA 1 Gene Mutation | BRCA 2 Gene MutationChina
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German Breast GroupAstraZenecaCompletedBreast Cancer | Triple Negative Breast Neoplasms | HRpos Breast Neoplasms | BRCA 1 /2 and / or HRDGermany
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BeiGeneRecruitingLocally Advanced or Metastatic Solid Tumors for Phase 1,Dose Escalation and Phase 2 Safety Lead-in, HNSCC, NSCLC and RCC Participants for Phase 2Australia, United States, Spain, France, Italy, Korea, Republic of, Poland
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Hadassah Medical OrganizationWithdrawnType 1 or 2 Diabetics
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Unità di Medicina della Riproduzione, ItalyCompletedIncrease the Number of Blastocyst to Biopsy for Preimplantation Genetic TestingItaly
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German Breast GroupGlaxoSmithKline; Stemline Therapeutics, Inc.Not yet recruitingBRCA1 Mutation | BRCA2 Mutation | PALB2 Gene Mutation | Hormone Receptor Positive HER-2 Negative Breast Cancer | Advanced or Metastatic Breast CancerGermany
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Institute of Child HealthCompletedAsa 1 and 2 Patients for Elective Surgery Requiring Caudal as Part of Their CareUnited Kingdom
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Institute of Child HealthCompletedASA 1-2 Requiring Intravenous Cannulation for General AnaesthesiaUnited Kingdom
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Dana-Farber Cancer InstituteJohns Hopkins University; M.D. Anderson Cancer Center; Mayo Clinic; University... and other collaboratorsActive, not recruitingCandidates for Hereditary Pancreatic Cancer TestingUnited States
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Dicerna Pharmaceuticals, Inc.CompletedKidney Diseases | Urologic Diseases | Genetic Disease | Primary Hyperoxaluria Type 1 (PH1) | Primary Hyperoxaluria Type 2 (PH2)Poland, United Kingdom, New Zealand, United States, Australia, Canada, France, Germany, Israel, Italy, Japan, Lebanon, Netherlands, Romania, Spain
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University of Illinois at Urbana-ChampaignLouisiana State University Health Sciences Center in New Orleans; Colorado... and other collaboratorsCompletedIntervention 1: Resilience and Coping for Healthcare Group | Intervention 2: Resilience and Coping for Healthcare Plus Additional Services | Waitlist Control GroupUnited States, Puerto Rico
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The University of New South WalesNational Health and Medical Research Council, Australia; Novo Nordisk A/S; Sydney...CompletedType 1 Diabetes | Puberty: >Tanner 2 Breast Development or Testis >4mlAustralia
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Associazione Italiana per lo Studio del PancreasGeneral and Pancreatic Surgery Unit, University of Verona; Fondazione Valsecchi and other collaboratorsRecruitingCandidates for Hereditary Pancreatic Cancer TestingItaly
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Massachusetts General HospitalNational Cancer Institute (NCI); Boston Medical CenterCompletedGenetic TestingUnited States
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Rambam Health Care CampusTechnion, Israel Institute of TechnologyUnknownGroup 1: Trauma Operation for Otherwise Healthy Patients | Group 2: Primary Tumors of Mesenchymal OriginIsrael
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National Institute of Neurological Disorders and...TerminatedMyotonic Dystrophy Type-1 | Myotonic Dystrophy Type-2United States
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Centre Hospitalier Universitaire de la RéunionNot yet recruitingBreast Cancer | BRCA2 Mutation | Genetic Disease
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Assistance Publique - Hôpitaux de ParisCompletedType 1 or 2 DiabetesFrance
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Bigfoot Biomedical Inc.Jaeb Center for Health ResearchEnrolling by invitation
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SinocareCompletedEvaluate the Safety and Efficacy of Sinocare CGM System Regarding Real Time Glucose Level MonitoringType 1 or Type 2 DiabetesChina
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Lupin Ltd.WithdrawnMyotonic Dystrophy Type 1 and Type 2
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Trinity Hypertension & Metabolic Research InstituteCompletedJNC 7 Stage 1 or 2 HypertensionUnited States
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University of UtahCompletedNewly Diagnosed Hormone Positive Clinical Stage 1 or 2 Breast CancerUnited States
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Rabin Medical CenterUnknownLynch Syndrome | BRCA1 Syndrome | BRCA2 SyndromeIsrael
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AO Clinical Investigation and Publishing DocumentationTerminatedDiabetes Mellitus 1 or 2 | Midfoot Charcot NeuroarthropathyGermany
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Samsung Medical CenterAstraZenecaCompletedTo Investigate the Prevalence of BRCA 1/2 Mutation Among Ovarian Cancer
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Columbia UniversityNational Heart, Lung, and Blood Institute (NHLBI); Alpha-1 FoundationActive, not recruitingAlpha 1-Antitrypsin Deficiency | Genetic DiseaseUnited States
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Memorial Sloan Kettering Cancer CenterRecruitingBreast Cancer | Pancreatic Cancer | Ovarian Cancer | Prostate Cancer | Educational Materials for Genetic TestingUnited States
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University of SaskatchewanGovernment of Canada; Vaccine Formulation Institute (VFI); Government of Saskatchewan and other collaboratorsActive, not recruitingDouble Vaccinated for COVID-19 (For Phase 1 of the Study) | Acute Respiratory Syndrome Coronavirus 2 (For Phase 2 Exploratory Group)Canada
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National Institute of Diabetes and Digestive and...CompletedProtocol #1:Behavioral Therapy + Placebo or Sibutramine | Protocol #2: Behavioral Therapy + Meal Replacement or Conventional Food
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Dicerna Pharmaceuticals, Inc., a Novo Nordisk companyEnrolling by invitationKidney Diseases | Urologic Diseases | Genetic Disease | Primary Hyperoxaluria Type 1 (PH1) | Primary Hyperoxaluria Type 2 (PH2) | Primary Hyperoxaluria Type 3 (PH3)United States, France, Germany, Japan, Lebanon, Spain, United Kingdom, Australia, Canada, Italy, Netherlands, Norway, Turkey
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University of California, IrvineWithdrawnAnesthetized Healthy Patients (ASA 1 or 2) in the Supine Position, Excluding Head, Neck and Head Surgeries | Anesthetized Patient With Severe Systemic Disease (ASA 3 or 4)United States
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GlucoMeTerminatedDiabetes Mellitus, Type 1 or 2Israel
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University Hospital, BonnForschungszentrum Juelich; The Marigold Foundation; Life and Brain Center BonnCompletedMyotonic Dystrophy 1 | Myotonic Dystrophy 2
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University of FloridaAcorda TherapeuticsCompletedSpinocerebellar Ataxias Type 1 | Spinocerebellar Ataxias Type 2 | Spinocerebellar Ataxias Type 3 | Spinocerebellar Ataxias Type 6United States
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AmgenCompletedPart 1- Advanced Solid Tumors | Part 2- Advanced or Metastatic Gastric Cancer | Part 2- Advanced or Metastatic GEJJapan
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Mannkind CorporationCompletedDiabetes, Type 2 | Diabetes, Type 1United States, Spain, Canada, Russian Federation, Czech Republic, Poland, Ukraine, United Kingdom
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Centre Hospitalier Universitaire DijonTerminatedPatients With Type 1 or Type 2 Diabetes | Patients With a Type A or B Behaviour ProfileFrance
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University Hospital ErlangenEdimer PharmaceuticalsCompletedHypohidrotic Ectodermal DysplasiaGermany
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University of FloridaAlpha-1 FoundationEnrolling by invitation
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Myotonic Dystrophy FoundationRecruitingMyotonic Dystrophy | Myotonic Dystrophy 1 | Steinert's Disease | Congenital Myotonic Dystrophy | PROMM (Proximal Myotonic Myopathy) | Steinert Disease | Dystrophia Myotonica 1 | Myotonic Dystrophy 2 | Dystrophia Myotonica | Dystrophia Myotonica 2 | Myotonia Dystrophica | Myotonic Dystrophy, Congenital | Myotonic... and other conditionsUnited States
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Institute of Molecular and Clinical Ophthalmology...RecruitingStargardt Disease | Stargardt Disease 1 | Fundus Flavimaculatus | Macular Degeneration, Stargardt | Macular Dystrophy With Flecks, Type 1Switzerland