Clinical Trials on Carbapenemase-producing Enterobacteriaceae Infection

Total 323 results

Assistance Publique - Hôpitaux de Paris

Recruiting

Rectal Carriage of Carbapenemase Producing-Enterobacteriaceae on Admission to a French University Teaching Hospital (Prev-CPE)

Rectal Carriage of Carbapenemase Producing-Enterobacteriaceae

France
Hospital Italiano de Buenos Aires

Recruiting

Incidence and Risk Factors for Developing Infections in Patients Colonized by CP-KPC (KPC)

Carbapenemase-Producing Enterobacteriaceae

Argentina
University Hospital, Strasbourg, France

Recruiting

Carbapenem Antibiotic Therapy for VIM Carbapenemase-Producing Enterobacteriaceae Infections (CarbaVim)

Carbapenemase-Producing Enterobacteriaceae

France
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Cost-effectiveness of Controlling CPE (OPTIM-BHRe)

Carbapenemase-producing Enterobacteriaceae Infections
Maimónides Biomedical Research Institute of Córdoba
Mikrobiomik Healthcare Company S.L.

Recruiting

Clinical Trial to Demonstrate the Effectiveness of Fecal Microbiota Transplantation for Selective Intestinal Decolonization of Patients Colonized by Carbapenemase-producing Klebsiella Pneumoniae (KAPEDIS)

Carbapenemase-producing Enterobacteriaceae Infection

Spain
University Hospital, Angers

Unknown

Factors Influencing the Fecal Relative Abundance of ESBL-producing Enterobacteriaceae in Intensive Care (BLSE-REA).

ESBL-producing Enterobacteriaceae Infections
Kaleido Biosciences

Terminated

VITORA: Clinical Study to Evaluate the Effect of KB109 on the Gut Microbiome in Subjects Whose Gastrointestinal Tracts Are Colonized With Multiple Drug-resistant Organisms (VITORA)

Vancomycin-Resistant Enterococcus, Extended-Spectrum Beta Lactamase-Producing Enterobacteriaceae, or Carbapenem-Resistant Enterobacteriaceae Colonized Subjects

United States
The Methodist Hospital Research Institute
M.D. Anderson Cancer Center; National Institute of Allergy and Infectious Diseases... and other collaborators

Recruiting

Dynamics of Colonization and Infection by Multidrug-Resistant Pathogens in Immunocompromised and Critically Ill Patients (DYNAMITE)

Antibiotic Resistant Infection | Clostridium Difficile | Antimicrobial Drug Resistance | Carbapenem-Resistant Enterobacteriaceae Infection | Vancomycin Resistant Enterococci Infection | Vancomycin-Resistant Enterococcal Infection | Carbapenem Resistant Bacterial Infection | Extended Spectrum Beta-Lactamase...

United States
University Hospital, Basel, Switzerland

Recruiting

Clinical Comparison of Treatment Strategies in AmpC Beta-lactamase Producing Enterobacterales in a Swiss Tertiary Care Hospital (AmpCstratBasel)

Infection With AmpC Beta-lactamase Producing Enterobacterales

Switzerland
Thallion Pharmaceuticals
LFB Biotechnologies, SAS

Completed

Study of Chimeric Monoclonal Antibodies to Shiga Toxins 1 and 2

Shiga Toxin Producing Bacterial Infection

Argentina, Peru, Chile
Rambam Health Care Campus

Completed

A Study Evaluating the Role of Oral Antibiotics in an Aim to Eradicate Carrier State of Carbapenem- Resistant Klebsiella Pneumonia (KPC).

Klebsiella Pneumoniae Carbapenemase Resistant Associated Bacteremia or Pneumonia

Israel
CHU de Reims

Completed

Qnr Genes in Enterobacteriaceae

Enterobacteriaceae Infection

France
Tan Tock Seng Hospital
Singapore Clinical Research Institute

Not yet recruiting

Oral Capsule Faecal Microbiota Transplantation for CPE Decolonization

Carbapenem-Resistant Enterobacteriaceae Infection
Qianfoshan Hospital

Recruiting

Drug Resistance Mechanism of Enterobacteriaceae and Its Strategies

Carbapenem-Resistant Enterobacteriaceae Infection

China
Rambam Health Care Campus

Completed

Fecal Microbiota Transplantation for Carbapenem-resistant Enterobacteriaceae

Carbapenem-Resistant Enterobacteriaceae Infection

Israel
Rambam Health Care Campus

Completed

Fecal Microbiota Transplantation for Carbapenem Resistant Enterobacteriaceae

Carbapenem-Resistant Enterobacteriaceae Infection

Israel
Hanoi University of Public Health
Karolinska Institutet; University of Copenhagen; National Children's Hospital... and other collaborators

Recruiting

Interventions to Decrease CRE Colonization and Transmission Between Hospitals, Households, Communities and Domesticated Animals (I-CRECT)

Antibiotic Resistant Infection | Carbapenem-Resistant Enterobacteriaceae Infection

Vietnam
Maimónides Biomedical Research Institute of Córdoba

Completed

Impact of Ceftazidime / Avibactam Treatment vs Better Available Therapy on Mortality of Patients With Infections Caused by Carbapenem-resistant Enterobacteria (CAVICOR)

Carbapenem-Resistant Enterobacteriaceae Infection

Spain
Children's Hospital of Fudan University

Recruiting

Risk Factors for Colonization or Infection With Carbapenem-Resistant Enterobacteriaceae in Children

Carbapenem-Resistant Enterobacteriaceae Infection

China
Sichuan Provincial People's Hospital

Not yet recruiting

Precise Treatment of Ceftazidime-Avibactam in Patients With CRO Infections Under the Guidance of TDM and PPK Model

ECMO | Carbapenem-Resistant Enterobacteriaceae Infection
Wake Forest University Health Sciences
Merck Sharp & Dohme LLC

Withdrawn

Imipenem/Cilastatin/Relebactam (IMI/REL) in Treatment of CRE Infections

Gram-Negative Bacterial Infections | Antibiotic Resistant Infection | Carbapenem-Resistant Enterobacteriaceae Infection | KPC

United States
Chuncheon Sacred Heart Hospital

Recruiting

The Effect of Fecal Microbiota Transplantation on the Decolonization of Multidrug-resistant Organisms

Carbapenem-Resistant Enterobacteriaceae Infection | Vancomycin-Resistant Enterococcal Infection

Korea, Republic of
The University of Hong Kong

Not yet recruiting

Fecal Microbiota Transplantation for Decolonization of Carbapenem-resistant Enterobacteriaceae (FMT)

Fecal Microbiota Transplantation | Carbapenem-Resistant Enterobacteriaceae Infection
King Faisal Specialist Hospital & Research Center

Recruiting

Ceftazidime-Avibactam Use in Critically Ill Patients With Carbapenem-Resistant Enterobacteriaceae Infections (AVI-ICU)

Carbapenem-Resistant Enterobacteriaceae Infection

Saudi Arabia
Assistance Publique - Hôpitaux de Paris

Terminated

Efficacy and Pharmacokinetic/Pharmacodynamic Parameters of Cefoxitin in Women With Acute Pyelonephritis Without Severity Symptoms Due to Extended-spectrum β-lactamase Producing Escherichia Coli (FOXICOLI)

Acute Pyelonephritis Without Severity Symptoms Due to ESBL-producing E.Coli

France
Hospital de Clinicas de Porto Alegre
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Terminated

Best Available Therapy With or Without Meropenem for Bloodstream Infections by Enterobacterales With High Level of Resistance to Carbapenems (ABOVE)

Bloodstream Infection | Carbapenem-Resistant Enterobacteriaceae Infection

Brazil
Academisch Medisch Centrum - Universiteit van Amsterdam...
Maastricht University Medical Center; Erasmus Medical Center; ZonMw: The Netherlands... and other collaborators

Completed

Carriage Of Multiresistant Bacteria After Travel (COMBAT)

Enterobacteriaceae, Infection

Netherlands
University of North Carolina, Chapel Hill
National Institute of Allergy and Infectious Diseases (NIAID)

Enrolling by invitation

Community-associated Highly-Resistant Enterobacterales (COCARE)

Enterobacteriaceae Infections | Community-Acquired Infections | Healthcare Associated Infection | Carbapenem-Resistant Enterobacteriaceae Infection

United States
Kocaeli University

Recruiting

A Novel Approach to Antimicrobial Resistance: Machine Learning Predictions for Carbapenem-Resistant Klebsiella in ICUs (ICU)

Artificial Intelligence | Intensive Care Unit | Carbapenem Resistant Enterobacteriaceae Infection

Turkey
Southeast University, China

Recruiting

Efficacy and Safety of Colistimethate Sodium for Injection in The Treatment of Carbapenem-Resistant Enterobacteriaceae Infection

Carbapenem-Resistant Enterobacteriaceae Infection

China
Hospital Moinhos de Vento

Terminated

Seven Versus 14 Days of Antibiotic Therapy for Multidrug-resistant Gram-negative Bacilli Infections (OPTIMISE)

Sepsis | Gram-Negative Bacterial Infections | Bacteremia | Severe Infection | Bloodstream Infection | Acinetobacter Infections | Pseudomonas Aeruginosa | Human | Carbapenem-Resistant Enterobacteriaceae Infection | Carbapenem Resistant Bacterial Infection

Brazil
Phramongkutklao College of Medicine and Hospital

Unknown

Optimizing Antibiotic Dosing Regimens for the Treatment of Infection Caused by Carbapenem Resistant Enterobacteriaceae

Sepsis | Critical Illness | Septic Shock | Clinical Outcomes | Treatment Outcomes | Drug Resistance | Carbapenem-Resistant Enterobacteriaceae Infection

Thailand
University of Bordeaux

Unknown

Gut Microbiota Association With ESBL-E Colonisation and Subsequent ESBL-E Infection (Microbe)

Critical Illness | Microbial Colonization | Extended Spectrum Beta-Lactamase Producing Bacteria Infection

France
Assistance Publique - Hôpitaux de Paris

Terminated

Deescalating Carbapenems in Hospital Setting (CARBEPARGNE)

Urinary Infection | Digestive Infection | Biliary Infection | Expanded-spectrum Beta-lactamase Producing ESBL
University of Pittsburgh
Centers for Disease Control and Prevention

Completed

NCCLS Interpretive Criteria for Salmonella

Salmonella Infection

United States
Groupe Hospitalier Paris Saint Joseph
Hospital Avicenne

Completed

Impact of Beta-lactams on the Microbiota and Relative Fecal Abundance of Mulltidrug Resistant Bacteria

Enterobacterial Infection

France
Centre Hospitalier Universitaire, Amiens

Completed

Nosocomial Outbreak of BHRe in an Intensive Care Unit During SARS-CoV-2 Pandemic (BHReICU)

Enterobacteriaceae Infections | Hospital-Acquired Infection

France
Phramongkutklao College of Medicine and Hospital
Silpakorn University

Recruiting

The Population Pharmacokinetics Study of Tigecycline and Pharmacokinetics- Pharmacodynamics Index in Patients With Carbapenem Resistant Enterobacteriaceae Bloodstream Infection

Carbapenem-resistant Enterobacteriaceae

Thailand
Alexion Pharmaceuticals

Completed

Safety and Efficacy Study of Eculizumab in Shiga-Toxin Producing Escherichia Coli Hemolytic-Uremic Syndrome (STEC-HUS) (STEC-HUS)

Shiga-like Toxin-producing Escherichia Coli

Germany
University of Tartu
Estonian University of Life Sciences

Unknown

Epidemiology of Resistant Microbial Strains Among Different Groups of People (Healthy, Infected and Exposed to Animals) (ABRESIST)

Methicillin Resistant Staphylococcus Aureus (MRSA) | Vancomycin (Glycopeptide) Resistant Enterococcus (VRE) | ESBL Producing E.Coli | ESBL Producing K.Pneumoniae | Multidrug Resistant P.Aeruginosa | Carbapenem Resistant P.Aeruginosa
Institute of Tropical Medicine, Belgium
KU Leuven; Université de Kisangani

Completed

Reservoir of Invasive Salmonellosis in Children, DRC

Salmonella Infections | Infection of Bloodstream

Congo, The Democratic Republic of the
University Hospital, Clermont-Ferrand
University Hospital, Estaing; Hopital Gabriel Montpied

Unknown

Assessment of the Prevalence of Extended-Spectrum Betalactamase Producing Enterobacteriaceae Among ICU Staff (REASSE)

Antibiotic Resistance | Extended-spectrum Betalactamase | Enterobacteriaceae | Escherichia Coli

France
U.S. Army Medical Research and Development Command

Completed

Safety Study of Chimeric Vaccine to Prevent ETEC Diarrhea

Escherichia Coli Infection

United States
U.S. Army Medical Research and Development Command

Completed

Safety Study of Recombinant Vaccine to Prevent ETEC Diarrhea

Escherichia Coli Infection

United States
UMC Utrecht
Janssen Research & Development, LLC; Innovative Medicines Initiative

Completed

Study to Collect Information About Invasive Disease Caused by Extraintestinal Pathogenic Escherichia Coli-2 (EXPECT-2) (EXPECT-2)

E. Coli Infection

United States, Italy, United Kingdom, Canada, France, Germany, Japan, Spain
Peking Union Medical College Hospital

Unknown

18F-FDS PET/CT in Healthy Volunteers and Patients With Suspected Infection

Enterobacteriaceae Infections

China
Ann & Robert H Lurie Children's Hospital of Chicago

Recruiting

Perinatal Transmission of MDR Bacteria (ACQUIRE)

Multi-antibiotic Resistance | E. Coli Infection

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Study of the Ecological and Evolutionary Dynamics of Escherichia Coli in the Digestive Commensal Flora (EVE)

Escherichia Coli; Infection, Intestinal

France
José Raimundo Araujo de Azevedo

Not yet recruiting

Resistance Profile of Escherichia Coli in Infections of Community Origin: The Importance of Antimicrobial Stewardship

Antimicrobial Resistance
University of Zurich

Unknown

Interaction Between Non-typhoid Salmonella, Host Microbiota, and Immune System During Acute Infection and Remission

Salmonella Infection Non-Typhoid

Switzerland

Clinical Trials on Carbapenemase-producing Enterobacteriaceae Infection

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