Clinical Trials on Carcinomas (Including Squamous Cell and Adenocarcinoma) in Canada

Total 1378 results

British Columbia Cancer Agency

Withdrawn

Dose Escalation Trial of Neoadjuvant Sorafenib and Concurrent Sorafenib, Cisplatin and Radiation in Locally Advanced Squamous Cell Carcinomas of the Head and Neck (SCCHN)

Locally Advanced Squamous Cell Carcinomas of the Head and Neck (SCCHN)

Canada
University Health Network, Toronto
AstraZeneca

Withdrawn

A Multi-Cancer, Multi-State, Platform Study of Durvalumab (MEDI4736) and Oleclumab (MEDI9447) in Pancreatic Adenocarcinoma, Non-Small Cell Lung Cancer and Squamous Cell Carcinoma of the Head and Neck to Correlate Clinical, Molecular and Immunologic Parameters With DNA Methylation (DOME)

Squamous Cell Carcinoma of Head and Neck | Non-small Cell Lung Cancer | Pancreatic Ductal Adenocarcinoma

Canada
University Health Network, Toronto
AstraZeneca; Mirati Therapeutics Inc.

Withdrawn

Pre-operative Mocetinostat (MGCD0103) and Durvalumab (MEDI4736) (PRIMED) for Squamous Cell Carcinoma of the Oral Cavity (PRIMED-001)

Squamous Cell Carcinoma, Head And Neck | Squamous Cell Carcinoma Mouth | Resectable Squamous Cell Carcinoma of Oral Cavity

Canada
University Health Network, Toronto
NuBiyota

Active, not recruiting

Role of Microbiome as a Biomarkers in Locoregionally-Advanced Oropharyngeal Squamous Cell Carcinoma 2 (ROMA LA-OPSCC2)

Head and Neck Squamous Cell Carcinoma

Canada
University Health Network, Toronto

Completed

Role of Microbiome as a Biomarkers in Locoregionally-Advanced Oropharyngeal Squamous Cell Carcinoma (ROMA LA-OPSCC)

Locoregionally-advanced Oropharyngeal Squamous Cell Carcinoma

Canada
AHS Cancer Control Alberta
EMD Serono; Alberta Cancer Foundation

Recruiting

The UNSCARRed Study: UNresctable Squamous Cell Carcinoma Treated With Avelumab and Radical Radiotherapy (UNSCARRed)

Squamous Cell Carcinoma of the Skin

Canada
National Cancer Institute (NCI)

Terminated

Cisplatin With or Without WEE1 Inhibitor MK-1775 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Recurrent Lip and Oral Cavity Squamous Cell Carcinoma | Recurrent Laryngeal Verrucous Carcinoma | Recurrent Metastatic Squamous Cell Carcinoma in... and other conditions

Canada
University Health Network, Toronto

Completed

Transoral Robotic Surgery and Tailored Radiotherapy in Unknown Primary and Small Squamous Cell Head and Neck Cancer (FIND)

Head and Neck Squamous Cell Carcinoma

Canada
University Health Network, Toronto

Recruiting

Head and Neck Squamous Cell Carcinoma (HNSCC)PET-CT Pilot Study

Head and Neck Squamous Cell Carcinoma

Canada
Ottawa Hospital Research Institute
GE Healthcare

Completed

Dual-Energy CT in Patients With Head and Neck Squamous Cell Carcinomas

Head and Neck Squamous Cell Carcinoma

Canada
University Health Network, Toronto
Pfizer

Completed

A Study of PF-00299804 When Given Through a Feeding Tube in Locally Advanced Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma

Canada
Jewish General Hospital
McGill University Health Centre/Research Institute of the McGill University...

Recruiting

Sentinel Lymph Node Biopsy for Cutaneous Squamous Cell Carcinoma of the Head and Neck

Sentinel Lymph Node | Cutaneous Squamous Cell Carcinoma

Canada
AHS Cancer Control Alberta
Alberta Cancer Foundation

Unknown

Nivolumab Plus Pemetrexed for Head and Neck Squamous Cell Carcinoma (NivoPlus)

SCCHN

Canada
University Health Network, Toronto

Completed

Biofeedback Rehabilitation to Improve Speaking and Eating in Public (Biofeedback)

Oral Cavity Squamous Cell Carcinoma

Canada
McMaster University
Juravinski Cancer Centre Foundation

Unknown

A Study of SBRT for Squamous Cell Carcinoma of the Head and Neck (SHINE)

Head and Neck Neoplasms | Squamous Cell Carcinoma | Squamous Skin Carcinoma

Canada
Lawson Health Research Institute

Recruiting

Radiotherapy vs. Trans-Oral Surgery for HPV-Negative Oropharyngeal Squamous Cell Carcinoma

Head and Neck Cancer | Oropharyngeal Squamous Cell Carcinoma

Canada
University Health Network, Toronto

Completed

Dacomitinib Plus Radiotherapy, With and Without Cisplatin in Patients With Squamous Cell Carcinoma of the Head and Neck

Squamous Cell Carcinoma of the Head and Neck

Canada
University Health Network, Toronto

Active, not recruiting

Multi-Omic Assessment of Squamous Cell Cancers Receiving Systemic Therapy (MASST)

Cancer | Metastatic Cancer | Squamous Cell Carcinoma of the Head and Neck | Anal Canal Squamous Cell Carcinoma | Esophagus Squamous Cell Carcinoma

Canada
Centre hospitalier de l'Université de Montréal...
AstraZeneca

Active, not recruiting

Immunotherapy and SBRT for Metastatic Head and Neck Carcinomas

Head and Neck Squamous Cell Carcinoma | Metastatic Squamous Cell Carcinoma

Canada
University Health Network, Toronto
Mirati Therapeutics Inc.

Completed

Sitravatinib (MGCD516) and Nivolumab in Oral Cavity Cancer Window Opportunity Study (SNOW)

Squamous Cell Carcinoma of the Oral Cavity | Squamous Cell Carcinoma, Head And Neck | Squamous Cell Carcinoma Mouth

Canada
Lawson Health Research Institute

Active, not recruiting

A Window of Opportunity Study to Assess the Modulation of Biomarkers in Head and Neck Squamous Cell Cancer (HNSCC) By Preoperative Treatment With BYL719

Head and Neck Squamous Cell Cancer

Canada
Lawson Health Research Institute
Champions Oncology

Completed

TumorGraft- Guided Therapy for Improved Outcomes in Head and Neck Squamous Cell Cancer- A Feasibility Study (Xenograft)

Head and Neck Squamous Cell Carcinoma

Canada
University of Calgary

Completed

Does the Harmonic Scalpel Reduce Blood Loss and OR Time in Major Head and Neck Cancer Surgery Undergoing Major Surgery for Oral Cavity Squamous Cell Carcinoma? (HS2)

Oral Cavity Squamous Cell Carcinoma, Treated With Surgery

Canada
National Cancer Institute (NCI)

Active, not recruiting

Onalespib in Treating Patients With Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck Receiving Radiation Therapy and Cisplatin

Stage IVA Hypopharyngeal Squamous Cell Carcinoma AJCC v7 | Stage IVA Laryngeal Squamous Cell Carcinoma AJCC v7 | Stage IVA Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7 | Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7 | Stage IVB Hypopharyngeal Squamous Cell Carcinoma AJCC v7 | Stage IVB Laryngeal Squamous Cell Carcinoma AJCC... and other conditions

United States, Canada
University Health Network, Toronto
Princess Margaret Hospital, Canada

Active, not recruiting

Real-time Detection of ctDNA and/or HPV DNA in High-risk Locally-advanced Head and Neck Squamous Cell Carcinoma

Cancer | Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma

Canada
AHS Cancer Control Alberta
University of Calgary; Calgary Health Region

Completed

PET-CT for Squamous Cell Carcinoma (SCC) of the Neck Nodes Unknown Primary Malignancy

Squamous Cell Cancer

Canada
University Health Network, Toronto
AstraZeneca; NeoGenomics Laboratories

Recruiting

Molecular Residual Disease Interception in Locoregionally-Advanced High Risk HPV+ and HPV- HNSCC (MERIDIAN)

Locoregionally Advanced Head and Neck Squamous Cell Carcinoma (LA-HNSCC)

Canada
National Cancer Institute (NCI)

Terminated

Capecitabine and Vorinostat in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer

Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Stage IVA Oral Cavity Squamous Cell Carcinoma | Stage IVA Laryngeal Squamous Cell Carcinoma | Stage... and other conditions

Canada, United States
University Health Network, Toronto
Novartis Pharmaceuticals

Completed

Phase I Study of BYL719 in Combination With Cisplatin and Radiotherapy in Patients With Squamous Cell Head and Neck Cancer

Squamous Cell Carcinoma of Head and Neck | Locoregionally Advanced

Canada
Shattuck Labs, Inc.

Active, not recruiting

SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas

Melanoma | Renal Cell Carcinoma | Hodgkin Lymphoma | Gastric Adenocarcinoma | Non Small Cell Lung Cancer | Squamous Cell Carcinoma of the Head and Neck | Diffuse Large B Cell Lymphoma | Urothelial Carcinoma | Gastroesophageal Junction Adenocarcinoma | Squamous Cell Carcinoma of the Skin | Squamous Cell Carcinoma... and other conditions

United States, Canada, Belgium, Spain
Lawson Health Research Institute

Recruiting

Low-Dose Weekly vs High-Dose Cisplatin (RADIO)

Locally Advanced Head and Neck Squamous Cell Carcinoma

Canada
Ottawa Hospital Research Institute
Ozmosis Research Inc.

Completed

Phase I Study of a Statin + Erlotinib for Advanced Solid Malignancies With Focus on Squamous Cell Carcinomas and NSCLC

Non-Small Cell Lung Cancer | Squamous Cell Carcinoma

Canada
University of Calgary
Terry Fox Research Institute

Completed

Fluorescent Visualization in Early Oral Cancer

Oral Squamous Cell Carcinoma or Severe Dysplasia

Canada
University Health Network, Toronto

Recruiting

HN-QUEST: A Study of Head and Neck Imaging Biomarkers (HN-Quest)

Head and Neck Squamous Cell Carcinoma

Canada
University Health Network, Toronto
Princess Margaret Hospital, Canada

Completed

Hardwins - Squamous Cell Carcinoma Head & Neck (Surgery/RT)

Carcinoma, Squamous Cell

Canada
University Health Network, Toronto
Princess Margaret Hospital, Canada

Completed

Study of Circulating Tumor DNA (ctDNA) Kinetics in Immuno-oncology (IO-KIN)

Head and Neck Cancer | Metastatic Cancer | Advanced Cancer | HNSCC | Squamous Cell Carcinoma

Canada
Sunnybrook Health Sciences Centre

Completed

Analysis of Patterns of Recurrence in Head and Neck Cancer Using Clinicopathomic Markers

Squamous Cell Carcinoma of Head and Neck | Head and Neck Neoplasm

Canada
Ivan Litvinov

Terminated

Imvamune Vaccine for the Treatment of Non-melanoma Skin Cancer (MUSIC-01)

Basal Cell Carcinoma | Squamous Cell Carcinoma | Non-melanoma Skin Cancer

Canada
National Cancer Institute (NCI)

Completed

SB-715992 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous Cell Carcinoma... and other conditions

Canada
NCIC Clinical Trials Group
Roche Pharma AG

Completed

Adjuvant Erlotinib After Completing Chemoradiotherapy in Locally Advanced Squamous Cell Carcinoma of the Head and Neck

Head and Neck Cancer

Canada
University of Alberta
Alberta Health services

Completed

2B or Not 2B? Shoulder Function After Level 2B Neck Dissection: A Randomized Controlled Study (2BN2B)

Head and Neck Squamous Cell Carcinoma

Canada
AHS Cancer Control Alberta
Cross Cancer Institute; Tom Baker Cancer Centre

Recruiting

p16+ Oropharyngeal Cancer Radiation Optimization Trial Reducing Elective Treatment Volumes (PROTEcT) (PROTEcT)

Squamous Cell Carcinoma of the Oropharynx

Canada
University of Alberta

Not yet recruiting

Heavy Strength Training in Head and Neck Cancer Survivors (LIFTING2)

Head and Neck Cancer | Head and Neck Neoplasms | Head and Neck Squamous Cell Carcinoma | Head and Neck Carcinoma

Canada
Jennerex Biotherapeutics

Completed

Safety Study of Recombinant Vaccinia Virus to Treat Refractory Solid Tumors

Melanoma | Renal Cell Carcinoma | Lung Cancer | Squamous Cell Carcinoma of the Head and Neck

United States, Canada
Lawson Health Research Institute

Recruiting

Preservation of Swallowing in Respected Oral Cavity Squamous Cell Carcinoma: Examining Radiation Volume Effects (PRESERVE): A Randomized Trial

Head and Neck Cancer

Canada, United States, Ireland, United Kingdom
RTOG Foundation, Inc.
Merck Sharp & Dohme LLC

Recruiting

SBRT +/- Pembrolizumab in Patients With Local-Regionally Recurrent or Second Primary Head and Neck Carcinoma (KEYSTROKE)

Head and Neck Squamous Cell Carcinoma (HNSCC)

Canada, United States
National Baromedical Services
Mayo Clinic; Dartmouth-Hitchcock Medical Center; CISSS de Chaudière-Appalaches; Memorial Hermann Hospital and other collaborators

Not yet recruiting

Hyperbaric Radiation Sensitization of Head and Neck Cancers

Squamous Cell Carcinoma of the Head and Neck

United States, Canada
Replimune Inc.
Regeneron Pharmaceuticals

Active, not recruiting

Study Evaluating Cemiplimab Alone and Combined With RP1 in Treating Advanced Squamous Skin Cancer (CERPASS)

Cutaneous Squamous Cell Carcinoma | Advanced Cutaneous Squamous Cell Carcinoma | Metastatic Cutaneous Squamous Cell Carcinoma

Spain, United States, France, Australia, Germany, Canada, Greece, Bulgaria, Italy, Poland
Transgene
Pfizer; EMD Serono Research & Development Institute, Inc.; Merck KGaA, Darmstadt...

Active, not recruiting

Phase Ib/II of TG4001 and Avelumab in HPV16 Positive R/M Cancers

HPV-Related Carcinoma | HPV-Related Cervical Carcinoma | HPV-Related Anal Squamous Cell Carcinoma | HPV-Related Penile Squamous Cell Carcinoma | HPV-Related Vulvar Squamous Cell Carcinoma

United States, France, Spain
Karyopharm Therapeutics Inc

Terminated

Selinexor Treatment of Advanced Relapsed/Refractory Squamous Cell Carcinomas (STARRS)

Squamous Cell Carcinoma

United States, Canada

Clinical Trials on Carcinomas (Including Squamous Cell and Adenocarcinoma) in Canada

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