Clinical Trials on Cardiac Defects

Total 12628 results

Ethem Unal, M.D., PhD, Associate Prof of Surgery...

Unknown

The Efficacy of Nifedipine in the Management of Preterm Labor (BOG/TH/PTL)

Preterm Birth | Preterm Labor | Preterm Labor Without Delivery | Side Effect of Drug | Preterm Labor With Preterm Delivery in Third Trimester | Calcium-Channel Blockers Toxicity
Radboud University Medical Center

Unknown

Early Detection of Cardiac Damage With CMR in Women With Breast Cancer (EARLY-CATCH)

Breast Cancer | Cardiotoxicity | Chemotherapy Induced Systolic Dysfunction

Netherlands
Seoul National University Hospital
Ministry of Health & Welfare, Korea

Completed

A Pharamcogenomic Study for Isoniazid According to NAT2 Polymorphism Status

Tuberculosis | Drug-Induced Liver Injury | Adverse Drug Event

Korea, Republic of
University of Washington
National Cancer Institute (NCI)

Completed

Memory and Thinking Skills Workshop to Improve Cognition in Gynecologic and Breast Cancer Survivors With Cognitive Symptoms

Breast Carcinoma | Cancer Survivor | Malignant Female Reproductive System Neoplasm | Cognitive Side Effects of Cancer Therapy

United States
Lexicon Pharmaceuticals

Completed

Telotristat Etiprate - Expanded Treatment for Patients With Carcinoid Syndrome Symptoms (TELEPATH)

Carcinoid Syndrome

United States, Australia, Belgium, Canada, France, Germany, Israel, Italy, Netherlands, Spain, Sweden, United Kingdom
University of California, Davis

Withdrawn

Topical Clobetasol for the Treatment of Toxic Epidermal Necrolysis (TEN)

Toxic Epidermal Necrolysis

United States
RAND
University of California, Los Angeles; Northwestern University; University of... and other collaborators

Unknown

Reducing High-Risk Geriatric Polypharmacy Via EHR Nudges: Pilot Phase

Fall | Congestive Heart Failure | Adverse Drug Event | Chronic Kidney Failure

United States
Cangzhou Hospital of Integrated Traditional Chinese...
Agency for Science, Technology and Research

Completed

Study on Continuous Intravenous of Unfractionated Heparin (UFH) to Treat Progressive Cerebral Infarction (UHPCI)

Acute Cerebral Ischemia | Heparin Causing Adverse Effects in Therapeutic Use | Heparin-induced Thrombosis

China
Mansoura University

Completed

Trigonal vs Non Trigonal Botox Injection in OAB.

Quality of Life | Urologic Diseases | Overactive Bladder Syndrome | Anticholinergic Syndrome
Lexicon Pharmaceuticals

Completed

Telotristat Etiprate for Carcinoid Syndrome Therapy (TELECAST)

Carcinoid Syndrome

United States, Australia, Belgium, Canada, France, Germany, Israel, Spain, Sweden, United Kingdom, Netherlands
Kessler Foundation
International Progressive MS Alliance

Completed

Treating New Learning and Memory Deficits in Progressive Multiple Sclerosis (MS)

Memory Impairment | Cognition - Other | Multiple Sclerosis, Progressive

United States
Spaulding Rehabilitation Hospital

Terminated

Galvanic Vestibular Stimulation and Motor Training in Traumatic Brain Injury Survivors

TBI | Motor Impairments | Attention Deficits

United States
University of Wisconsin, Madison
National Cancer Institute (NCI)

Completed

Side Effects of High-Dose Intensity-Modulated Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer

Head and Neck Cancer | Radiation Toxicity | Long-term Effects Secondary to Cancer Therapy in Adults | Oral Complications of Radiation Therapy
London School of Hygiene and Tropical Medicine
Armauer Hansen Research Institute, Ethiopia; Alert Hospital, Ethiopia; Homes...

Completed

Ciclosporin in the Management of Chronic or Recurrent Erythema Nodosum Leprosum

Leprosy

Ethiopia
Endo Pharmaceuticals

Terminated

Pharmacokinetics, Efficacy and Safety of an Octreotide Implant in Patients With Carcinoid Syndrome

Carcinoid Syndrome

United States
Jay F. Piccirillo, MD
Barnes-Jewish Hospital; Washington University Siteman Cancer Center

Completed

Chemotherapy-Induced Cognitive Impairment (CICI)

Cognitive Symptoms

United States
National University of Ireland, Galway, Ireland
Clinical Research Facility Galway; CORRIB Research Centre for Advanced Imaging...

Recruiting

Understanding CARdiac Events in Breast Cancer (UCARE)

Heart Failure | Breast Cancer | Cardiomyopathies | Cardiotoxicity | Chemotherapeutic Toxicity | Oncology

Ireland
Imperial College London

Recruiting

Video Game Hearing Tests for Remote Monitoring of Ototoxicity (VAROT)

Hearing Loss | Aminoglycoside Toxicity | Video Games | Aminoglycoside-Induced Hearing Loss

United Kingdom
Samara State Medical University

Recruiting

Clinical and Diagnostic Significance of Endothelial Dysfunction and Myocardial Contractility in Patients With AML

Endothelial Dysfunction | Cardiotoxicity | Acute Myeloid Leukemia, Adult

Russian Federation
Tianjin Medical University General Hospital

Not yet recruiting

Propranolol on Post Stroke Immune Status and Infection

Cardiovascular Diseases | Stroke | Cerebrovascular Disorders | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Ischemic Stroke | Molecular Mechanisms of Pharmacological Action | Physiological Effects of Drugs | Propranolol | Immunologic Factors | Beta Blocker

China
Peking University People's Hospital

Recruiting

The Combination of Sitagliptin and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia

Blood Coagulation Disorders | Thrombocytopenia | Immune Thrombocytopenia | Physiological Effects of Drugs

China
Children's National Research Institute

Recruiting

Feasibility and Efficacy of Attentional-Control Training in Sickle Cell Disease (ACT)

Sickle Cell Disease | Cognitive Deficit in Attention | Attention Deficit

United States
Fundacion CRIS de Investigación para Vencer el...
BTG International Inc.; BioClever 2005 S.L.; Eurofins ADME, S.L.; NTShub, S.L.

Terminated

Reduction of MTX Levels After Glucarpidase Treatment in DLBCL Patients at Risk of CNS

Diffuse Large B-Cell Lymphoma | Drug Toxicity

Spain
University of Texas Southwestern Medical Center

Active, not recruiting

Hyperpolarized Carbon 13-Based Metabolic Imaging to Detect Radiation-Induced Cardiotoxicity

Thoracic Cancer | Left Sided Breast Cancer

United States
Lexicon Pharmaceuticals

Completed

Study of Telotristat Etiprate (LX1606) in Participants With Symptomatic Carcinoid Syndrome Not Managed by Stable-Dose Octreotide Therapy

Carcinoid Syndrome

United States
Lexicon Pharmaceuticals

Completed

TELESTAR (Telotristat Etiprate for Somatostatin Analogue Not Adequately Controlled Carcinoid Syndrome)

Carcinoid Syndrome

United States, Australia, Belgium, France, Germany, Italy, Netherlands, Spain, Sweden, United Kingdom, Canada, Israel
Air Liquide Santé International
Orion Corporation, Orion Pharma

Completed

Xenon Compared to Sevoflurane and Total Intravenous Anaesthesia for Coronary Artery Bypass Graft Surgery

Coronary Artery Disease | Coronary Artery Bypass Graft Surgery | General Anesthetic Drug Allergy

France, Italy, Germany, Netherlands
Peking University Cancer Hospital & Institute

Completed

Study the Role of Stem Cell in Curing Drug Induced Liver Injury in Metastatic Breast Cancer (MBC) (MBC)

Breast Neoplasms | Neoplasm Metastasis

China
University Hospital, Lille
Institut National de la Santé Et de la Recherche Médicale, France

Completed

Outcome of Patients Treated by iv Rt-PA for Cerebral Ischaemia According to the Ratio Sc-tPA/Tc-tPA (OPHELIE)

Stroke, Acute | Drug Toxicity

France
Boston Medical Center
Amgen

Withdrawn

Study of Panitumumab in the Treatment of Carcinoid Syndrome

Carcinoid Syndrome

United States
PATH

Completed

Preliminary Evaluation of a Point-Of-Care Liver Function Test (DFA)

HIV | Tuberculosis | Drug-Induced Liver Injury

Vietnam
University of Pernambuco

Completed

Stevens-Johnson Syndrome Antimicrobial

Stevens-Johnson Syndrome

Brazil
Roopa Kanakatti Shankar, MBBS, MS

Recruiting

Vosoritide for Short Stature in Turner Syndrome

Turner Syndrome | Short Stature

United States
dr. Laura C. G. de Graaff-Herder

Recruiting

Turner And Klinefelter Treatment Target Study (TAKTT)

Turner Syndrome | Klinefelter Syndrome

Netherlands
University of North Carolina, Chapel Hill
The Hospital for Sick Children; Washington University School of Medicine; McGill... and other collaborators

Recruiting

Defining the Genetic Etiology of Suppurative Lung Disease in Children and Adults

Primary Ciliary Dyskinesia | Kartagener Syndrome | Primary Immune Deficiency

United States, Canada
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Niguarda Hospital

Recruiting

Combined Lung Ultrasounds and Transthoracic Electrical Bioimpedance in Preterm Infants With Respiratory Distress.

Respiratory Distress Syndrome in Premature Infant | Patent Ductus Arteriosus After Premature Birth | Perinatal Morbidity

Italy
McMaster University
Harvard Medical School (HMS and HSDM); The Hospital for Sick Children; Canadian... and other collaborators

Terminated

READYorNot[TM] Brain-Based Disabilities Trial

Epilepsy | Cerebral Palsy | Autism Spectrum Disorder | Spina Bifida | Fetal Alcohol Spectrum Disorders

Canada
Stanford University
Alagille Syndrome Alliance

Enrolling by invitation

Decreasing Hemorrhage Risk in Children With Alagille Syndrome

Alagille Syndrome | Acquired Von Willebrand Disease | Pulmonary Artery Stenoses

United States
Holland Bloorview Kids Rehabilitation Hospital
The Hospital for Sick Children; University of Toronto; University of Ottawa; Social... and other collaborators

Completed

A Peer E-mentoring Intervention to Improve Employment

Cerebral Palsy | Muscular Dystrophy | Physical Disability | Spinal Cord Injury | Spina Bifida | Juvenile Arthritis

Canada
Hacettepe University

Completed

Effect of Game Based Approach on Oxygenation, Functional Capacity and Quality of Life in Primary Ciliary Dyskinesia

Primary Ciliary Dyskinesia | Kartagener Syndrome | Immotile Cilia Syndrome

Turkey
Natera, Inc.

Completed

Development of Non-invasive Prenatal Test for Microdeletion and Other Genetic Syndromes Based on Cell Free DNA (Microdel Triad)

Trisomy 21 | Trisomy 18 | Trisomy 13 | Sex Chromosome Abnormalities | Microdeletion Syndromes

United States
Göteborg University
Sahlgrenska University Hospital, Sweden

Enrolling by invitation

Sahlgrenska Cardiomyopathy Project

Myocarditis | Hypertrophic Cardiomyopathy | Arrhythmogenic Right Ventricular Cardiomyopathy | Restrictive Cardiomyopathy | Dilated Cardiomyopathies | Giant Cell Myocarditis | Amyloidosis; Heart (Manifestation) | Sarcoidosis With Myocarditis

Sweden
Genentech, Inc.

Completed

Bone Mineral Density (BMD) in Adolescents With Growth Hormone Deficiency (GHD)

Dwarfism, Pituitary | Turner Syndrome
Hospital Sirio-Libanes
Daiichi Sankyo

Not yet recruiting

Vitamin K AntagonISt, Factor Xa Inhibitor Or Nothing In Atrial Fibrillation And DIalytic End-stage Renal DiseasE (VISIONAIRE) (VISIONAIRE)

Chronic Kidney Diseases | Atrium; Fibrillation
Second Affiliated Hospital, School of Medicine,...

Recruiting

Combination of Antiplatelet and Anticoagulation for AIS Patients Witn Concomitant NVAF and Extracranial/Intracranial Artery Stenosis (ALLY)

Atrial Fibrillation | Acute Ischemic Stroke | Intracranial Atherosclerosis | Stenosis, Carotid

China
AgileMD, Inc.
University of Chicago; University of Wisconsin, Madison; Department of Health... and other collaborators

Recruiting

A Rapid Diagnostic of Risk in Hospitalized Patients Using Machine Learning

COVID-19 | Sepsis | Respiratory Failure | Cardiac Arrest | Hemodynamic Instability | Septicemia | Clinical Deterioration

United States
Bahawal Victoria Hospital Bahawalpur

Recruiting

Different Approaches of Spinal Anesthesia in Patients Undergoing Cesarean Section

Respiratory Failure | Bradycardia | Hypotension | Meningitis | Hematoma | Post-Dural Puncture Headache | Spinal Shock

Pakistan
Bispebjerg Hospital
Göteborg University; Rigshospitalet, Denmark; University of Basel; University of... and other collaborators

Recruiting

COMPuter-assisted Self-training to Improve EXecutive Function (COMPEX)

Stroke | Parkinson Disease | Cognitive Dysfunction | Cardiac Arrest | Executive Dysfunction

Denmark
Bayer

Completed

A Study to Learn How the Study Treatment Asundexian Moves Into, Through and Out of the Body, How it Works, How Safe it is, and How it Affects the Body in Participants With Mild or Moderate Reduction of Liver Function Compared to Participants With Normal Liver Function

Atrial Fibrillation | Hepatic Impairment | Acute Myocardial Infarction | Prevention of Thromboembolic Events | Non-cardioembolic Ischemic Stroke

Germany
Shahid Beheshti University of Medical Sciences

Completed

MLC901 in Hypoxic-ischemic Brain Injury Patients; A Double-blind, Randomized Placebo-controlled Trial

Hypoxic Ischaemic Encephalopathy Due to Cardiac Arrest

Iran, Islamic Republic of

Clinical Trials on Cardiac Defects

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Japan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations