Clinical Trials on Castleman Disease

Total 379290 results

Affiliated Hospital to Academy of Military Medical...
Cancer Institute and Hospital, Chinese Academy of Medical Sciences; Peking...

Recruiting

Phase II Trial of Tirelizumab Combined With R2-ICE Regimen in the Treatment of rrDLBCL/HGBL

Age Range ≥16 Years, Gender Unlimited | Histopathology Confirmed Diffuse Large B-cell Lymphoma or High-grade B-cell Lymphoma | Received Prior First-line Chemotherapy for DLBCL or HGBL, Failed to Reach CR for Four Cycles, or Relapsed | At Least One Positive Lesion According to the 2014... and other conditions

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Hypofractionated Partial Breast Irradiation in Treating Patients With Early Stage Breast Cancer

Invasive Breast Carcinoma | Early-Stage Breast Carcinoma | Stage I Breast Cancer AJCC v7 | Stage IA Breast Cancer AJCC v7 | Stage IB Breast Cancer AJCC v7 | Stage II Breast Cancer AJCC v6 and v7 | Stage IIA Breast Cancer AJCC v6 and v7 | Stage IIB Breast Cancer AJCC v6 and v7 | Ductal Breast Carcinoma... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Withdrawn

Effects of Ribociclib and Palbociclib on Tumor and Blood Characteristics in Patients With Metastatic Breast Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage IIIA Breast Cancer AJCC v8 | Prognostic Stage IIIB Breast... and other conditions
Roswell Park Cancer Institute
National Cancer Institute (NCI); Cianna Medical, Inc.

Terminated

Radiation Therapy in Treating Post-Menopausal Women With Early Stage Breast Cancer Undergoing Surgery

Stage I Breast Cancer | Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIC Breast Cancer | Lobular Breast Carcinoma In Situ | Estrogen Receptor Negative | Estrogen Receptor Positive | HER2/Neu Negative | Progesterone Receptor Positive | Ductal Breast Carcinoma In Situ | Mucinous Breast Carcinoma | Tubular Breast Carcinoma and other conditions

United States
National Cancer Institute (NCI)

Suspended

Testing Pembrolizumab Versus Observation in Patients With Merkel Cell Carcinoma After Surgery, STAMP Trial

Pathologic Stage I Cutaneous Merkel Cell Carcinoma AJCC v8 | Pathologic Stage II Cutaneous Merkel Cell Carcinoma AJCC v8 | Pathologic Stage III Cutaneous Merkel Cell Carcinoma AJCC v8

United States
OHSU Knight Cancer Institute
Oregon Health and Science University; American Society of Clinical Oncology; Radiological... and other collaborators

Withdrawn

Y-90 Versus SBRT for Inoperable HCC

Hepatocellular Carcinoma | Stage III Hepatocellular Carcinoma AJCC v8 | Stage IIIA Hepatocellular Carcinoma AJCC v8 | Stage IVA Hepatocellular Carcinoma AJCC v8 | Stage IIIB Hepatocellular Carcinoma AJCC v8 | Stage IB Hepatocellular Carcinoma AJCC v8 | Stage II Hepatocellular Carcinoma AJCC v8 | Stage... and other conditions

United States
Brown University
Actuate Therapeutics Inc.

Withdrawn

Phase 2 Study of 9-ING-41 With Chemotherapy in Sarcoma

Soft Tissue Sarcoma | Osteosarcoma | Ewing Sarcoma of Bone | Leiomyosarcoma | High Grade Sarcoma | Liposarcoma | Rhabdomyosarcoma | Angiosarcoma | Bone Sarcoma | Synovial Sarcoma | Undifferentiated Pleomorphic Sarcoma | Myxofibrosarcoma | Spindle Cell Sarcoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Amifostine in Treating Children With Malignant Germ Cell Tumors

Ovarian Cancer | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor | Drug/Agent Toxicity by Tissue/Organ

United States, Canada, Netherlands, Puerto Rico, Switzerland, Australia
University Hospital Southampton NHS Foundation...
National Institute for Health Research, United Kingdom

Recruiting

Eye Movement Desensitisation and Reprocessing (EMDR) to Improve Mental Health Following Intensive Care Admission (EMERALD)

Critical Illness | Post Traumatic Stress Disorder | Depression, Anxiety | Eye Movement Desensitisation and Reprocessing

United Kingdom
Lei Li

Recruiting

Donafenib for Recurrent Cervical Cancer

Chemotherapy | Recurrent Cervical Carcinoma | Survival Outcomes | Targeted Therapy | Adverse Effect | Metastatic Cervical Carcinoma | Persistent Advanced Cervical Carcinoma

China
Lei Li

Recruiting

Combination of Nimotuzumab and Radiotherapy for Recurrent Uterine Cervical Squamous Carcinoma

Recurrent Cervical Carcinoma | Radiotherapy | Objective Response Rate | Overall Survival | Progression-free Survival | Epidermal Growth Factor Receptor | Nimotuzumab

China
University of Illinois at Chicago
National Institute of Mental Health (NIMH)

Recruiting

Unobtrusive Monitoring of Affective Symptoms and Cognition Using Keyboard Dynamics (UnMASCK) (UnMASCK)

Mood Disorders | Major Depressive Disorder | Bipolar Disorder I | Bipolar Disorder II | Persistent Depressive Disorder (Dysthymia) | Cyclothymia

United States
University of Utah

Active, not recruiting

Salvage Oligometastasectomy and Radiation Therapy in Recurrent Prostate Cancer (SOAR)

Prostate Adenocarcinoma | Metastatic Malignant Neoplasm in the Bone | Metastatic Malignant Neoplasm in the Lymph Nodes | Recurrent Prostate Carcinoma | Oligometastasis | PSA Failure

United States
Arkin
Amsterdam UMC, location VUmc; Ziekenhuis Amstelland; Meander Medisch Centrum; Sinai... and other collaborators

Completed

Effectiveness of PTSD-treatment Compared to Integrated PTSD-PD-treatment in Adult Patients With Comorbid PTSD and CPD (PROSPER-C)

Posttraumatic Stress Disorder (PTSD) | Avoidant Personality Disorder | Dependent Personality Disorder | Obsessive Compulsive Personality Disorder

Netherlands
Universitair Ziekenhuis Brussel

Unknown

Early Screening of Emotional, Behavioral and Autism Spectrum Disorders in Children With Functional Constipation.

Autism Spectrum Disorder | Functional Constipation | Developmental Disorder | Emotional Problems | Behavioural Problems

Belgium
Merrimack College
Pennington Biomedical Research Center; University of Massachusetts, Worcester; Boston Medical Center Developmental and Behavioral Pediatrics Clinic and other collaborators

Completed

Expanded Game Squad for Neurodiverse Youth (NDGameSquad)

Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse) | Physical Activity | Health Behavior | Developmental Disorder

United States
University of Texas at Austin

Unknown

Neuroimaging of Pavlovian Fear Conditioning Processes in Patients With Pathological Anxiety

Anxiety Disorders | Post Traumatic Stress Disorder | Panic Disorder | Social Phobia | Phobia

United States
Hugo W. Moser Research Institute at Kennedy Krieger...

Completed

National Child Traumatic Stress Network (NCTSN) Quality Improvement Initiative Database

Depression | Anxiety | ADHD | Conduct Disorder | Post Traumatic Stress Disorder

United States
University of Pittsburgh

Completed

Treatment of Young Adults With Comorbid AUD/MDD: A Pilot Medication Trial (YAAD-P)

Major Depressive Disorder | Alcohol Use Disorder

United States
Yale University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Terminated

Zonisamide for Heavy Drinkers With Bipolar Disorder (ZNSBP)

Bipolar Disorder | Alcohol Use Disorders

United States
AstraZeneca

Completed

Recurrence Rate, Risk Factors for the Recurrence, and Quality of Life in Patients With GERD in Korea-an Observational (Refresh)

The Aim of This Study is to Investigate the Frequency and Related Risk Factors of Recurrence, and Quality of Life in Patients With GERD After Treatment With PPI

Korea, Republic of
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Durvalumab and Tremelimumab Before Surgery in Treating Patients With Hormone Receptor Positive, HER2 Negative Stage II-III Breast Cancer

Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Radiation Therapy in Treating Patients With Stage 0-II Breast Cancer

Invasive Breast Carcinoma | Stage I Breast Cancer AJCC v7 | Stage IA Breast Cancer AJCC v7 | Stage IB Breast Cancer AJCC v7 | Stage II Breast Cancer AJCC v6 and v7 | Stage IIA Breast Cancer AJCC v6 and v7 | Stage IIB Breast Cancer AJCC v6 and v7 | Breast Adenocarcinoma | Ductal Breast Carcinoma In Situ and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Sapanisertib and Nivolumab for the Treatment of Stage I-IV Non-small Cell Lung Cancer in Patients Who Have Progressed on Prior PD-1/PD-L1 Inhibitor Therapy, I-OVERCOME Study

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage II Lung Cancer AJCC v8 | Stage IIA Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung... and other conditions
University of California, Los Angeles
Brown University; The Miriam Hospital; Rhode Island Hospital

Not yet recruiting

Emergency Medicine Peer Outreach Worker Engagement for Recovery (EMPOWER)

Opioid Use Disorder | Substance Use Disorders | Alcohol Use Disorder | Overdose
University of California, San Francisco
The CARESTAR Foundation

Terminated

Emergency Department Initiated Extended-Release Naltrexone and Case Management for the Treatment of Alcohol Use Disorder

Substance Use | Alcohol Use Disorder | Alcohol Abuse or Dependence

United States
UConn Health
National Institute on Drug Abuse (NIDA)

Completed

Integrated Treatment for Posttraumatic Stress Disorder and Substance Abuse in Young Adults

Substance Use Disorder | Posttraumatic Stress Disorder

United States
Lei Li

Completed

First-line Chemotherapy for Recurrent Cervical Cancer

Chemotherapy | Recurrent Cervical Carcinoma | Apatinib | Targeted Therapy | Persistent Advanced Cervical Carcinoma | Vascular Endothelial Growth Factor 2 Inhibitor

China
Mayo Clinic

Completed

ICU Doulas Providing Psychological Support

Depression | Cognitive Impairment | Anxiety | Post Traumatic Stress Disorder | Illness, Critical

United States
VA Connecticut Healthcare System

Completed

Naltrexone Plus Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use Disorder

Major Depressive Disorder | Alcohol Use Disorder
Harvard School of Public Health (HSPH)
Judge Baker Children's Center

Completed

Manville Moves: an Exercise Intervention for Behavioral Regulation Among Children With Behavioral Health Challenges (MM)

Mood Disorders | Anxiety Disorders | Attention Deficit and Disruptive Behavior Disorders | Autistic Disorder | Conduct Disorder | Oppositional Defiant Disorder

United States
Duke University
National Institute of Mental Health (NIMH)

Completed

Antidepressant Safety in Kids Study (ASK)

Obsessive Compulsive Disorder | Anxiety Disorders | Eating Disorders | Depressive Disorders

United States
Shalvata Mental Health Center
Weizmann Institute of Science

Unknown

Evaluation of Generalization Paradigm Patterns Among Different Psychiatric Disorders

PTSD | Bipolar Disorder | MDD | Schizophrenia Disorder | Anxiety Disorder (Panic Disorder or GAD)

Israel
Beijing Tiantan Hospital

Not yet recruiting

Transauricular Vagal Nerve Stimulation Improves Postoperative Delirium in Elderly Patients (Vnstar-IIa)

Vagus Nerve Stimulation

China
Armando Santoro, MD
GlaxoSmithKline; Istituto Clinico Humanitas

Not yet recruiting

Niraparib and Temozolomide in Patients Glioblastoma (ONC-2022-001)

Glioma, Malignant

Italy
Umraniye Education and Research Hospital

Recruiting

Effects of Pericapsular Nerve Group Block Applied in Patients Undergoing Hip Fracture Surgery.

Pain, Postoperative | Hip Fractures

Turkey
University of Minnesota

Not yet recruiting

Supervised Treadmill Intervention to Reduce Inflammation and Depression Through Exercise in HIV: The STRIDE Pilot Study

Depression | Hiv
Duke University

Not yet recruiting

Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of the Oncolytic HSV1 MVR-C5252 (PuMP)

Recurrent High Grade Glioma
Peking Union Medical College Hospital

Recruiting

First- Line Treatment With Durvalumab Plus XELOX Chemotherapy in Advanced Gastrointestinal Neuroendocrine Carcinoma

Gastrointestinal Neuroendocrine Carcinoma

China
University Hospital, Antwerp

Recruiting

Standardised Drug Provocation Testing in Perioperative Hypersensitivity

Hypersensitivity | Anaphylaxis | Allergic Reaction | Perioperative Complication | Immediate Hypersensitivity | Hypersensitivity, Drug | Anaphylactic Reaction

Belgium
Aveta Biomics, Inc.

Recruiting

Treatment of Patients With Recurrent High-Grade Glioma With APG-157 and Bevacizumab

Glioma | Glioblastoma Multiforme

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

Effect of Preoperative Olfactory Training on Postoperative Delirium in the Elderly Undergoing Orthopedic Surgeries

Postoperative Delirium | Preoperative Olfactory Training
Elizabeth J Franzmann
Aveta Biomics, Inc.

Recruiting

A Proof of Concept Trial Investigating Safety and Efficacy of APG-157 in Oral Dysplasia

Oropharyngeal Dysplasia | Oral Cavity Dysplasia | Oral Carcinoma in Situ

United States
International Food Policy Research Institute
Bill and Melinda Gates Foundation

Recruiting

Improving Birth Outcomes in Bangladesh

Birth Weight | Gestational Weight Gain | Diet; Deficiency | Small for Gestational Age at Delivery

Bangladesh
Gaziantep Islam Science and Technology University

Not yet recruiting

The Effect of Guided Imagery and Diaphragmatic Breathing Exercise in Pregnant Women With Hyperemesis Gravidarum

Hyperemesis Gravidarum
Imperial College London

Recruiting

[18F]FPIA PET-CT in Glioblastoma Multiforme (GBM) (FAM-GBM)

Glioblastoma Multiforme of Brain

United Kingdom
Emory University
National Cancer Institute (NCI); Verastem, Inc.

Recruiting

Identification of Treatment Concentrations of Defactinib or VS-6766 for the Treatment of Patients With Glioblastoma

Glioblastoma | Recurrent Glioblastoma

United States
BeyondBio Inc.

Recruiting

A Study to Evaluate Safety and Efficacy of BEY1107 in Combination With Temozolomide in Patients With Recurrent or Progressive Glioblastoma Multiforme (GBM)

Glioblastoma Multiforme

Korea, Republic of
Biocad

Recruiting

A Study of Neoadjuvant Therapy With BCD-217 (Nurulimab + Prolgolimab) in Patients With Resectable Stage III Skin Melanoma (NEO-MIMAJOR)

Melanoma (Skin) | Melanoma Stage III

Russian Federation, Belarus
Hospices Civils de Lyon
International Agency for Research on Cancer

Recruiting

Assessment of Tobacco Smoking and Alcohol Drinking and Treatment Outcomes Among Patients With Lung or Head and Neck Cancer (SMALLHAN)

Lung or Head and Neck Cancer

France

Clinical Trials on Castleman Disease

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Drug Interventions

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