Clinical Trials on Catabolic State in South Africa

Total 2813 results

Wits Health Consortium (Pty) Ltd
Discovery Vitality

Active, not recruiting

Testing the Effectiveness of Different Messaging Approaches to Increase Doctor Visits Amongst Individuals With Risk Factors for Diabetes

Type 2 Diabetes | Pre-diabetes

South Africa
Advanced Imaging Projects, LLC
University of Witwatersrand, South Africa; Postgraduate Institute of Medical...

Not yet recruiting

A Phase I/II Multicenter, Open-Label Study of Lu-177-DOTAGA-IAC, for the Treatment of Angiogenic Breast Cancer Patients. (Heroine01)

Breast Cancer Stage IV

India, South Africa
Alvotech Swiss AG

Active, not recruiting

AVT03 With Xgeva in Healthy Male Subjects

This is a Phase Study Conducted in Healthy Volunteers

South Africa
AstraZeneca

Completed

Centralized Pan-South African Survey on the Undertreatment of Hypercholesterolaemia (CEPHEUS)

Undertreatment of Hypercholesterolaemia

South Africa
Boehringer Ingelheim

Completed

To Determine Blood Concentrations of Ibuprofen and Caffeine in a Tablet Against Ibuprofen Alone From Another Tablet

Healthy

South Africa
Alvotech Swiss AG

Active, not recruiting

Multicenter Study in Postmenopausal Women With Osteoporosis, ALVOBOND (ALVOBOND)

Osteoporosis, Postmenopausal

South Africa
University of Witwatersrand, South Africa

Terminated

Differences Between Stavudine and Tenofovir Each Combined With Lamivudine and Efavirenz in SA HIV-infected Patients (CHRU01)

Metabolic Complications | Mitochondrial Toxicity

South Africa
Eli Lilly and Company

Completed

A Study to Compare the Pharmacokinetics and Pharmacodynamics of LY2963016 to Lantus in Healthy Participants

Diabetes Mellitus

South Africa
Novo Nordisk A/S

Completed

Bioequivalence of Two Formulations of Biphasic Insulin Aspart 70 in Healthy Male Subjects

Healthy | Diabetes

South Africa
Novo Nordisk A/S

Completed

Comparison of Two Insulin Aspart Formulations in Healthy Volunteers

Healthy | Diabetes

South Africa
Novo Nordisk A/S

Completed

Bioequivalence of Two Formulations of Biphasic Insulin Aspart 50 in Healthy Male Subjects

Healthy | Diabetes

South Africa
University of Pretoria

Unknown

The Efficacy of Specialist Collaboration and Mobile Screening for Improving the Management of Diabetes (CCMSD)

Diabetes

South Africa
Swiss Federal Institute of Technology
North-West University, South Africa

Completed

Omega-3 Fatty Acid Supplementation and Fractional Iron Absorption in Obese South African Women

Obesity

South Africa
Medical Research Council, South Africa
University of Wisconsin, Madison; International Atomic Energy Agency

Completed

Total Body Vitamin A Before and After Vitamin A Supplementation in a Community Where Liver is Frequently Eaten

Hypervitaminosis A

South Africa
Swiss Federal Institute of Technology
University of Stellenbosch

Completed

Stable Iron Isotope Method in HIV+ and HIV- Children

Iron-deficiency

South Africa
Swiss Federal Institute of Technology
University of Stellenbosch

Recruiting

Potential of Prebiotic Galacto-oligosaccharides in Improving Efficacy and Safety of Oral Iron Supplementation in HIV-infected Children

HIV | Iron Deficiency

South Africa
University of Pretoria
South African Sugar Association

Completed

Nutrition Education Intervention for Adults With Type 2 Diabetes

Type 2 Diabetes Mellitus

South Africa
Cycle Pharmaceuticals Ltd.
Parexel

Completed

Bioequivalence Study of Two Oral Nitisinone Formulations to Treat Hereditary Tyrosinemia (HT-1)

Hereditary Tyrosinemia, Type I

South Africa
University of Witwatersrand, South Africa
GlaxoSmithKline; University of Oxford; Medical Research Council, South Africa; University...

Completed

Determinants of Type 2 Diabetes Risk in Middle-aged Black South African Men and Women

Diabetes Mellitus, Type 2 | Insulin Resistance | Menopause | Hiv

South Africa
Cycle Pharmaceuticals Ltd.
Parexel

Completed

Bioavailability Food-Effect Study of an Oral Nitisinone Formulation to Treat Hereditary Tyrosinemia (HT-1)

Hereditary Tyrosinemia, Type I

South Africa
Cycle Pharmaceuticals Ltd.
Parexel

Completed

Bioequivalence Study of Two Nitisinone Formulations Compared to Orfadin

Hereditary Tyrosinemia, Type I

South Africa
Microbiome Health Research Institute
University of Cape Town

Terminated

Transfer of Healthy Gut Flora for Restoration of Intestinal Microbiota Via Enema for Patients in the Rehabilitative Phase of Malnutrition (THRIVE)

Moderate Acute Malnutrition | Severe Acute Malnutrition

South Africa
University of Cape Town

Unknown

Pregnancy-Related Obesity Prevention Through Education & Communication Technology in AFRICA:The PROTECT-AFRICA STUDY (PROTECT-AFRI)

Obesity

South Africa
University of Witwatersrand, South Africa
UNITAID

Completed

CHARACTERISE - A Cross-sectional, Observational Study to Characterise the Transition to Dolutegravir-based Regimens in South Africa in Terms of the Emergence of Obesity, Viral Re-suppression and Integration Into Routine Programme Care (CHARACTERISE)

Dolutegravir

South Africa
Boston University
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Completed

Non-Communicable Diseases and Antiretroviral Therapy Outcomes in the RapIT Study Population (RapIT-NCD)

Cardiovascular Diseases | Diabetes Mellitus, Type 2 | Antiretroviral Therapy, Highly Active

South Africa
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of Arkansas; The Emmes Company, LLC; University of Stellenbosch

Withdrawn

Testing the Addition of Paclitaxel and Carboplatin Given After Standard Chemotherapy and Radiation for Cervical Cancer in HIV-positive Women

HIV Infection | Cervical Adenocarcinoma | Cervical Adenosquamous Carcinoma | Cervical Squamous Cell Carcinoma, Not Otherwise Specified | FIGO Stage IIB Cervix Carcinoma | FIGO Stage III Cervix Carcinoma | FIGO Stage IVA Cervix Carcinoma

South Africa, Zimbabwe
North-West University, South Africa
Global Alliance for Improved Nutrition; Unilever R&D; DSM Ltd

Completed

Randomized Controlled Trial in South Africa Comparing the Efficacy of Complementary Food Products on Child Growth (TSWAKA)

Malnutrition

South Africa
Children's Mercy Hospital Kansas City
University of the Western Cape

Completed

Adapting the Diabetes Prevention Program for a Developing World Context

Weight Loss

South Africa
Boston University
World Bank (Lead institution); Republic of South Africa National Department...

Completed

Evaluation of South Africa's National Adherence Strategy (ENHANCE)

Hypertension | Diabetes | HIV | Tuberculosis

South Africa
University of Witwatersrand, South Africa
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Completed

Effectiveness of a Pre-adolescent Inter-generational Intervention to Address HIV and Obesity

Obesity | Hiv

South Africa
University of California, Los Angeles
National Institute of Mental Health (NIMH); University of Stellenbosch

Active, not recruiting

Improving South African Government Workers' Capacities to Deliver HIV Interventions

Depression | Malnutrition | HIV | Partner Violence | Alcohol Use/Abuse

South Africa
University of Cape Town

Completed

Impact of Employee Wellness Programme

Obesity

South Africa
Cycle Pharmaceuticals Ltd.
FARMOVS Clinical Research Organisation

Completed

Bioequivalence Study of Two Oral Haloperidol Tablets Formulations in Healthy Subjects Under Fed Conditions

Bioequivalence

South Africa
Bukwang Pharmaceutical
Contera Pharma ApS

Completed

Efficacy and Safety of JM-010 in PD With Levodopa-Induced Dyskinesia (LID)

Parkinson's Disease | Levodopa Induced Dyskinesia (LID)

South Africa
University of KwaZulu
Cambridge University Hospitals NHS Foundation Trust; University of Oxford; University...

Completed

Durban Diabetes Study:A Study of the Epidemiology of Diabetes Mellitus in Urban South Africans of African Descent (DDS) (DDS)

Hyperglycemia | Diabetes Mellitus | Glucose Intolerance | Hereditary Diseases

South Africa
Lannett Company, Inc.
Parexel; FARMOVS (Pty) Ltd

Completed

A Study to Demonstrate Pharmacokinetic and Pharmacodynamic Biosimilarity Between HEC-Glargine and US-Lantus® in Healthy Male Volunteers

Type 2 Diabetes Mellitus | Type 1 Diabetes Mellitus

South Africa
North-West University, South Africa
Medical Research Council, South Africa; Swiss Federal Institute of Technology; Unilever R...

Completed

The Effects of Iron and Omega-3 Fatty Acid Supplementation on Cognition and Immune Function in Iron Deficient Children (FeFA)

Anemia | Iron Deficiency

South Africa
University of Stellenbosch

Completed

Prevalence of Hospital Malnutrition in Adult Patients

Malnutrition

South Africa
UCB Pharma

Completed

Cardiac Effects of Rotigotine Transdermal System in Subjects With Advanced-stage Idiopathic Parkinson's Disease

Parkinson's Disease

South Africa
Sanofi

Completed

Immunogenicity and Safety of Pentaxim in South African Infants

Pertussis | Tetanus | Diphtheria | Poliomyelitis | Haemophilus Infections

South Africa
University of Virginia
University of Venda

Active, not recruiting

Effectiveness of Point-of-use Water Treatment Technologies to Prevent Stunting Among Children in South Africa

Environmental Exposure | Diarrhoea;Infectious;Presumed | Diarrhea, Infantile | Diarrhea Tropical | Enteropathy | Malnutrition, Child

South Africa
North-West University, South Africa
GlaxoSmithKline; Novartis; Pfizer; Boehringer Ingelheim; Medical Research Council; Medical... and other collaborators

Active, not recruiting

The African-PREDICT Study (PREDICT)

Cardiovascular Diseases | Hypertension | Health Risk Behaviors | Arterial Stiffness | Young | Renin Hypertension

South Africa
AstraZeneca

Completed

Type III Dysbetalipoproteinemia

Hyperlipoproteinemia Type III

South Africa, Norway
University of Stellenbosch
University of Rochester; Fogarty International Center of the National Institute...

Recruiting

A Pilot Study of Metformin to Reduce Cerebrovascular Dysfunction in Participants With HIV and Metabolic Syndrome. (SMART)

Metabolic Syndrome | HIV Seropositivity

South Africa
DePuy International

Terminated

A Single Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Primary Hip Resurfacing Surgery

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Nonunion of Femoral Fractures

South Africa
International Maternal Pediatric Adolescent AIDS...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

TASK-002: Bioequivalence of Bedaquiline 400mg Administered in Crushed Form Compared to Tablet Form in Healthy Male and Female Adults Under Fed Conditions (BDQ Crush Study)

Tuberculosis

South Africa
North-West University, South Africa
Medical Research Council, South Africa; National Research Foundation of South... and other collaborators

Completed

Effect of African Leafy Vegetables on Nutritional Status of South African School Children. (ALV)

Malnutrition | Vitamin A Status | Iron Status | Zinc Status

South Africa
University of Pretoria
Nestlè Nutrition Institute Africa; South African Sugar Association

Completed

Nutrition Education Intervention in Adults With Type 2 Diabetes Mellitus in a Resource Poor Setting

Diabetes Mellitus, Type II [Non-insulin Dependent Type] [NIDDM Type] Uncontrolled

South Africa
University of Cape Town

Completed

The Impact of Obesity on Cardiac Function in Pregnancy (CFOP)

Obesity | Pregnancy

South Africa
Sanofi Pasteur, a Sanofi Company

Completed

DTaP-IPV-HB-PRP-T Combined Vaccine as a Primary Series and a Second Year of Life Booster in HIV-Exposed Infected and Uninfected Infants

Hepatitis B | Pertussis | Tetanus | Diphtheria | Polio | Human Immunodeficiency Virus Infection

South Africa

Clinical Trials on Catabolic State in South Africa

Sponsors and Collaborators

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CROs in Slovakia

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