Clinical Trials on Catastrophic Antiphospholipid Syndrome

Total 34158 results

Chinese University of Hong Kong

Enrolling by invitation

Prevalence and Etiologies of Intracranial Stenosis in Patients With Antiphospholipid Syndrome (ICAS_APS)

Antiphospholipid Syndrome | Stenosis | Intracranial Stenosis

Hong Kong
Assiut University

Unknown

Measurement of Anti-dsDNA by Both CLIFT & ELISA

Antiphospholipid Syndrome
Institute of Hematology & Blood Diseases Hospital

Recruiting

Anti-CD38 Antibody Treating APS With Thrombocytopenia

Thrombocytopenia | Antiphospholipid Syndrome

China
Imperial College London

Completed

Longitudinal Study of the Clinical and Haematological Cause of Women With Antiphospholipid Antibodies.

Antiphospholipid Syndrome

United Kingdom
National and Kapodistrian University of Athens

Completed

Hydroxychloroquine for Thrombosis Prevention and Antiphospholipid Antibody Reduction in Primary Antiphospholipid Syndrome

Antiphospholipid Syndrome

Greece
Scott C. Woller, MD
Bristol-Myers Squibb; University of Utah

Completed

Apixaban for Secondary Prevention of Thromboembolism Among Patients With AntiphosPholipid Syndrome (ASTRO-APS)

Thrombosis | Antiphospholipid Syndrome

United States
Zhang Lei, MD

Recruiting

Safety and Efficacy of Zanubrutinib in the Treatment of Antiphospholipid Syndrome With Secondary Thrombocytopenia

Thrombocytopenia | Antiphospholipid Syndrome | Treatment

China
Hospital for Special Surgery, New York
The New York Community Trust; AntiPhospholipid Syndrome Alliance For Clinical...

Terminated

Hydroxychloroquine for the First Thrombosis Prevention in Antiphospholipid Antibody Positive Patients

Antiphospholipid Syndrome

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Register of Patients With Anti-Phospholipids Syndrome (APS) and/or Systemic Lupus Erythematosus (SLE) (SAPL-LUPUS)

Anti-Phospholipids Syndrome (APS) | Systemic Lupus Erythematosus (SLE)

France
Mohamed Sayed Abdelhafez

Completed

Timing of Initiation of LMWH Administration in Pregnant Women With APS

Recurrent Miscarriage | Antiphospholipid Syndrome

Egypt
Hospital for Special Surgery, New York
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Recruiting

Predictors of Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS) (PROMISSE)

Systemic Lupus Erythematosus | Antiphospholipid Syndrome

United States, Canada, United Kingdom
Insel Gruppe AG, University Hospital Bern

Recruiting

Antiphospholipid Syndrome and Postpartum Pulmonary Artery Pressure

Pulmonary Hypertension | Antiphospholipid Syndrome in Pregnancy | Pre-Eclampsia; Complicating Pregnancy

Switzerland
Cardioangiologisches Centrum Bethanien

Completed

Effectivity and Safety of Different Anticoagulants in Patients With Thromboembolic Antiphospholipid Syndrome

Venous Thromboembolism | Antiphospholipid Syndrome | Major Bleed | Arterial Thromboembolism

Germany
Shanghai First Maternity and Infant Hospital
Fudan University; Xinhua Hospital, Shanghai Jiao Tong University School of... and other collaborators

Not yet recruiting

A Study of Hydroxychloroquine Sulfate in the Treatment of Recurrent Spontaneous Abortion With Antiphospholipid Syndrome

Recurrent Miscarriage | Antiphospholipid Syndrome

China
McMaster University
International Society on Thrombosis and Haemostasis

Recruiting

Registry on Augmented Antithrombotic Treatment Regimens for Patients With Arterial Thrombotic APS

Antiphospholipid Syndrome | Arterial Thrombosis

Argentina, Canada
Groupe Hospitalier Pitie-Salpetriere

Completed

Monitoring the Antiphospholipid Syndrome:TOXicity of Drugs (APSTOX) (APSTOX)

Antiphospholipid Syndrome | Adverse Drug Event | Drug Toxicity | Immune Disease

France
Woman's Health University Hospital, Egypt

Unknown

Preconceptional Thromboprophylaxis in Recurrent PREGNANCY LOSSES Caused by Antiphospholipid Syndrome

Recurrent Pregnancy Losses | Positive Anti Phospholipid Syndrome

Egypt
Mohamed Sayed Abdelhafez

Recruiting

Use of Warfarin After the First Trimester in Pregnant Women With APS

Recurrent Miscarriage | Antiphospholipid Syndrome

Egypt
Centre Hospitalier Universitaire de Nīmes

Completed

Assessment of the Prevalence of Major Psychiatric Disorders in a Cohort of Women With Clinical Criteria Corresponding to Pure, Abortive-form, Obstetrical, Antiphospholipid Syndrome (NOHA-PSY)

Antiphospholipid Syndrome | Factor V Leiden Thrombophilia

France
Stéphane Zuily
International Society on Thrombosis and Haemostasis

Recruiting

International Registry of Thrombotic APS Patients Treated With Direct Oral Anticoagulants (OBSTINATE)

Thrombosis | Antiphospholipid Syndrome | Anticoagulants Causing Adverse Effects in Therapeutic Use

France
Cairo University
Ahmed Elgazzar Hospital

Completed

Low-molecular-weight Heparin (LMWH) Versus Unfractionated Heparin (UFH) in Pregnant Women With Recurrent Abortion Secondary to Antiphospholipid Syndrome

Recurrent Abortion

Egypt
Saint Thomas Hospital, Panama

Unknown

Antiphospholipid Antibodies and Early Severe Preeclampsia.

Antiphospholipid Syndrome | Severe Preeclampsia

Panama
Centre Hospitalier Universitaire, Amiens

Completed

Clinical Significance of Antiphospholipid Antibodies in Healthy Subjects (SAPL)

Antiphospholipid Antibodies

France
Santé Arménie French-Armenian Research Center

Recruiting

Armenian NAtionwide REGistry of Systemic Autoimmune and Autoinflammatory Diseases (NAREG)

Rheumatoid Arthritis | Celiac Disease | Giant Cell Arteritis | Sjogren's Syndrome | Takayasu Arteritis | Primary Antiphospholipid Syndrome | Behcet Disease | Antineutrophil Cytoplasmic Antibody (ANCA) Positive Vasculitis | Hereditary and Acquired Angioedema

Armenia
Central Hospital, Nancy, France

Completed

Hypercoagulable Phenotype by Thrombinography (in Presence of C Protein Dynamic Inhibitory System) (TACT)

Venous Thrombosis
Saint Thomas Hospital, Panama

Unknown

Antiphospholipid Antibodies and Fetal Growth Restriction

Antiphospholipid Syndrome | Fetal Growth Restriction

Panama
Seoul National University Hospital
Samjin Pharmaceutical Co., Ltd.

Recruiting

Comparison of Clopidogrel-based Antiplatelet Therapy Versus Warfarin as Secondary Prevention Strategy for AntiPhospholipid Syndrome-related STROKE (APS-STROKE)

Cardiovascular Diseases | Ischemic Stroke | Transient Ischemic Attack | Antiphospholipid Syndrome | Cerebrovascular Disease | Major Bleed

Korea, Republic of
Assistance Publique - Hôpitaux de Paris
National Research Agency, France

Completed

Phenomics in Autoimmune and Inflammatory Diseases (TRANSIMMUNOM)

Rheumatoid Arthritis | Uveitis | Vasculitis | Type 1 Diabetes | Crohn's Disease | Myositis | Healthy Volunteer | Ankylosing Spondylitis | FMF | Systemic Lupus Erythematosus/Antiphospholipid Syndrome | Cryopyrin-Associated Periodic Syndromes /TNF-receptor Associated Periodic Syndrome | Ulcerative Rectocolitis | Unclassified...

France
University College, London
King's College Hospital NHS Trust; University College London Hospitals; Barts... and other collaborators

Active, not recruiting

RIvaroxaban for Stroke Patients With AntiPhospholipid Syndrome (RISAPS)

Stroke | Ischemic Stroke | Brain Ischemia | Systemic Lupus Erythematosus | Antiphospholipid Syndrome

United Kingdom
Centre Hospitalier Universitaire de Nīmes

Completed

Evaluation of the Incidence of Cancer in the Follow-up of Women With 3 Consecutive Embryonic Demises Before 10 Weeks or 1 Fetal Death, According to Their Thrombophilia Status, With a Special Focus on Women With an Obstetric Antiphospholipid Symdrome (oAPS) (NOHA-K)

Cancer | Pregnancy Related | Antiphospholipid Syndrome

France
National Taiwan University Hospital

Unknown

The Influence of Antiphospholipid Antibodies on the Relationship Between Hyperurecemia, Gout and Metabolic Syndrome (URIC)

Metabolic Syndrome | Endothelial Dysfunction | Hyperuricemia | Antiphospholipid Syndrome | Gout

Taiwan
China Immunotech (Beijing) Biotechnology Co., Ltd.
Shanghai Changzheng Hospital

Not yet recruiting

An Clinical Study of YTS109 Cell Injection in Subjects With Recurrent/Refractory Autoimmune Disease

Systemic Lupus Erythematosus | Systemic Sclerosis | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Sjogren's Syndrome | Antiphospholipid Syndrome | Inflammatory Myopathy
Bioray Laboratories
Shanghai Changzheng Hospital

Recruiting

Universal CAR-T Cells (BRL-301) in Relapse or Refractory Autoimmune Diseases

Systemic Sclerosis | Sjogren's Syndrome | Antiphospholipid Syndrome | Systemic Lupus Erythematosus (SLE) | ANCA Associated Systemic Vasculitis | Inflammatory Myopathy

China
Chugai Pharmaceutical

Not yet recruiting

Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)

Antiphospholipid Syndrome (APS) | Immune Thrombocytopenia (ITP) | Dermatomyositis (DM) | Bullous Pemphigoid (BP) | Behçet's Syndrome (BS) | Immune-mediated Necrotizing Myopathy (IMNM)

United States, Japan
Central Hospital, Nancy, France

Not yet recruiting

Impact of Antiphospholipid Antibodies on Thrombin Generation During Sars-CoV2 Infection (TACIT2 Study) (TACIT2)

COVID-19 | Antiphospholipid Syndrome

France
University of Puerto Rico
National Heart, Lung, and Blood Institute (NHLBI); Hartford Hospital; VA Caribbean...

Completed

Pharmacogenetics of Warfarin in Puerto Ricans.

Atrial Fibrillation | Deep Vein Thrombosis | Antiphospholipid Syndrome | Coagulopathy | Cardiac Valvular Insufficiency

Puerto Rico
LumiraDx UK Limited

Completed

Evaluation of Precision and Accuracy of INR Measurements in a Point of Care Device (OPTIMAL) (OPTIMAL)

Atrial Fibrillation | Thrombophilia | Deep Vein Thrombosis | Antiphospholipid Syndrome | Pulmonary Embolism | Post-Myocardial Infarction Syndrome | Artificial Heart Device User

United Kingdom
Hopital Lariboisière

Completed

Drug Interaction Between Paracetamol and Warfarin (INPAWA2)

Stroke | Atrial Fibrillation | Antiphospholipid Syndrome | Pulmonary Embolism | Deep Venous Thrombosis

France
Shanghai Changzheng Hospital

Recruiting

Anti-CD19-CD3E-CAR-T Cells in Relapsed/Refractory Autoimmune Disease

Systemic Sclerosis | Sjogren's Syndrome | Antiphospholipid Syndrome | ANCA Associated Vasculitis | Systemic Lupus Erythematosus (SLE) | Inflammatory Myopathy

China
First Affiliated Hospital of Wenzhou Medical University
Shanghai First Song Therapeutics Co., Ltd

Not yet recruiting

The Safety and Efficacy of Anti-CD19 CAR-T Cells in Patients With Relapsed/Refractory Autoimmune Diseases

Systemic Sclerosis | Sjogren's Syndrome | Antiphospholipid Syndrome | ANCA Associated Vasculitis | Systemic Lupus Erythematosus (SLE) | Inflammatory Myopathy

China
Cardioangiologisches Centrum Bethanien

Completed

Prospective Observational Study to Evaluate a Possible Change in APS Antibody Profiles After COVID-19 Infection or Vaccination (APSantiCo)

Antiphospholipid Syndrome | COVID-19 Infection | COVID-19 Vaccination

Germany
Shanghai First Maternity and Infant Hospital

Unknown

Neutrophil Extracellular Traps Mediate Antiphospholipid Antibody-induced Pregnancy Loss

Neutrophil Extracellular Traps; Antiphospholipid Antibody-induced Pregnancy Loss

China
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Unknown

Safety and Efficacy of Anti-Pandemic H1N1 Vaccination in Rheumatic Diseases

Rheumatoid Arthritis | Systemic Vasculitis | Juvenile Idiopathic Arthritis | Antiphospholipid Syndrome | Sjögren's Syndrome | Spondyloarthritis | Systemic Lupus Erythematosus (SLE) | Systemic Sclerosis (SSc) | Dermatomyositis (DM) | DMixed Connective Tissue Disease | Juvenile SLE | Juvenile DM

Brazil
Institut de Recherches Internationales Servier
Servier Bio-Innovation LLC

Not yet recruiting

Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation (PyramIDH)

Myelodysplastic Syndromes (MDS) | Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS)
SCRI Development Innovations, LLC
Novartis Pharmaceuticals

Terminated

LBH589 in Refractory Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndromes (MDS)

United States
PersImmune, Inc
University of California, San Diego

Unknown

Collection of Samples From Patients With MDS

Myelodysplastic Syndromes(MDS)

United States
TJ Biopharma Co., Ltd.

Recruiting

A Phase 3 Clinical Study to Evaluate Lemzoparlimab for Injection in Combination With Azacitidine (AZA) Versus AZA Monotherapy in Treatment-naïve Patients With Higher-risk Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndromes(MDS)

China
National Heart, Lung, and Blood Institute (NHLBI)
National Cancer Institute (NCI)

Recruiting

The National Myelodysplastic Syndromes (MDS) Study (MDS)

Myelodysplastic Syndromes (MDS)

United States, Israel
AbbVie
Genentech, Inc.

Active, not recruiting

A Study Evaluating Venetoclax in Combination With Azacitidine in Participants With Treatment-Naïve Higher-Risk Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndromes (MDS)

United States, Australia, Canada, France, Germany, Italy, United Kingdom
AbbVie
Celgene; Genentech, Inc.

Completed

A Study Evaluating Venetoclax Alone and in Combination With Azacitidine in Participants With Relapsed/Refractory Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndromes (MDS)

United States, Australia, Germany

Clinical Trials on Catastrophic Antiphospholipid Syndrome

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