Clinical Trials on Central Nervous System Embryonal Neoplasm in United Kingdom

Total 75560 results

Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

Genetic Study of Newly Diagnosed Central Nervous System Tumors in Young Children

Central Nervous System Embryonal Neoplasm

United States
European Organisation for Research and Treatment...

Unknown

Enzastaurin and Temozolomide in Treating Patients With Primary Gliomas

Brain and Central Nervous System Tumors

United Kingdom
Children's Cancer and Leukaemia Group

Unknown

Tumor Tissue, Blood Samples, and Family History in Predicting Tumor Development and Response to Treatment in Young Patients With Low-Grade Glioma

Brain and Central Nervous System Tumors

United Kingdom
Children's Cancer and Leukaemia Group

Unknown

Etoposide in Treating Young Patients With Relapsed Ependymoma

Brain and Central Nervous System Tumors

United Kingdom
European Organisation for Research and Treatment...

Completed

Acridine Carboxamide in Treating Patients With Recurrent Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United Kingdom
Societe Internationale d'Oncologie Pediatrique

Completed

Surgery Plus Radiation Therapy With or Without Chemotherapy in Treating Children With Primitive Neuroectodermal Tumors of the CNS

Brain and Central Nervous System Tumors

United Kingdom
Cancer Research UK

Terminated

Boron Phenylalanine With or Without Mannitol in Treating Patients With Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United Kingdom
The Leeds Teaching Hospitals NHS Trust

Unknown

Multi-parametric MRI/Fluorine-18 Fluciclovine PET-CT in Glioblastoma

Tumor, Brain

United Kingdom
Societe Internationale d'Oncologie Pediatrique

Completed

Radiation Therapy or Combination Chemotherapy in Treating Patients With Clinically or Radiologically Progressive Low-Grade Gliomas (SIOP-LGG-2004)

Primary Central Nervous System Neoplasms

France, United Kingdom, Italy, Germany, Switzerland, Belgium, Denmark, Norway, Austria, Croatia, Poland, Portugal
Ourotech, Inc.
Imperial College Healthcare NHS Trust

Recruiting

Prospective Evaluation of AI R&D Tool in Adult Glioma and Other Primary Brain Tumours (PEAR-GLIO) (PEAR-GLIO)

Glioblastoma | Brain Tumor | Ependymoma | Oligodendroglioma | Glioma, Malignant

United Kingdom
Societe Internationale d'Oncologie Pediatrique

Unknown

Carboplatin Plus Vincristine in Treating Children and Adolescents With Low Grade Glioma

Brain and Central Nervous System Tumors

United Kingdom, Italy, Germany
Imperial College London

Recruiting

Use of Non-invasive Optical Analysis in Neurosurgery

Glioma | Meningioma | Brain Metastases | Schwannoma | Brain Tumour

United Kingdom
Cancer Research UK

Completed

Olaparib and Temozolomide in Treating Patients With Relapsed Glioblastoma

Brain and Central Nervous System Tumors

United Kingdom
AstraZeneca

Completed

Phase I : Cediranib in Combination With Lomustine Chemotherapy in Recurrent Malignant Brain Tumour

Brain Tumor | Recurrent Glioblastoma

United States, United Kingdom
National Cancer Institute (NCI)

Completed

Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors

Refractory Malignant Solid Neoplasm | Pineoblastoma | Recurrent Malignant Solid Neoplasm | Recurrent Medulloblastoma | Recurrent Neuroblastoma | Recurrent Rhabdomyosarcoma | Refractory Medulloblastoma | Refractory Neuroblastoma | Refractory Rhabdomyosarcoma | Central Nervous System Embryonal Tumor With... and other conditions

United States, Canada
Cancer Research UK
Immatics Biotechnologies GmbH

Completed

Vaccine Therapy, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United Kingdom
University of Oxford
Oxford University Hospitals NHS Trust

Terminated

Enhanced Detection in Glioma Excision (EDGE)

Glioma

United Kingdom
Celgene

Completed

A Study of Pomalidomide Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors

Central Nervous System Neoplasms | Medulloblastoma

United States, Italy, France, Spain, United Kingdom
University of Southampton
University Hospital Southampton NHS Foundation Trust

Unknown

Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors (GemTIP)

Testicular Germ Cell Tumor | Ovarian Cancer | Brain and Central Nervous System Tumors | Extragonadal Germ Cell Tumor

United Kingdom
European Organisation for Research and Treatment...

Completed

Erlotinib Compared With Temozolomide or Carmustine in Treating Patients With Recurrent Glioblastoma Multiforme

Brain and Central Nervous System Tumors

France, Italy, Belgium, Netherlands, United Kingdom
Societe Internationale d'Oncologie Pediatrique
Children's Cancer and Leukaemia Group; Italian Association for Pediatric Hematology...

Completed

Combination Chemotherapy Followed by Radiation Therapy in Treating Children With Localized Ependymoma

Brain and Central Nervous System Tumors

Canada, United Kingdom, Netherlands, Spain, Sweden, Argentina, Italy
European Organisation for Research and Treatment...

Completed

Imatinib Mesylate in Treating Patients With Gliomas

Brain and Central Nervous System Tumors

France, Switzerland, Italy, Belgium, Austria, United Kingdom, Netherlands
University of California, San Francisco
National Cancer Institute (NCI)

Completed

Temozolomide in Treating Patients With Recurrent High-Grade Glioma

Recurrent Central Nervous System Neoplasm

United States
University of Leicester

Unknown

Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma

Brain and Central Nervous System Tumors

United Kingdom, Belgium, Germany, Netherlands, France, Sweden, Italy, Spain
King's College Hospital NHS Trust
Guy's and St Thomas' NHS Foundation Trust

Recruiting

Use of DTT to Define Facial Nerve Position in Vestibular Schwannomas

Vestibular Schwannoma

United Kingdom
University College, London
University College London Hospitals

Unknown

Novel Multimodality Imaging for Navigation in Skull Base Surgery (SBN)

Vestibular Schwannoma

United Kingdom
John Sampson
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients Undergoing Surgery for Recurrent Glioblastoma Multiforme

Recurrent Central Nervous System Neoplasm

United States
Royal Marsden NHS Foundation Trust
National Institute for Health Research, United Kingdom

Completed

Comparing Immobilisation Shells in Cranial Radiotherapy (CORIOLIS)

Bone Metastases | Brain Metastases | Brain Tumor, Primary | Brain Tumor Adult | Brain Tumor - Metastatic

United Kingdom
Institute of Cancer Research, United Kingdom

Completed

Temozolomide Compared to Procarbazine, Lomustine, and Vincristine in Treating Patients With Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United Kingdom
M.D. Anderson Cancer Center
Cortice Biosciences, Inc.

Terminated

Phase I/II Bevacizumab Versus Bevacizumab Plus TPI 287 for Recurrent Glioblastoma

Brain Neoplasms | Central Nervous System Neoplasms

United States
National Cancer Institute (NCI)

Completed

Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab

Glioblastoma | Brain Neoplasms | Central Nervous System Neoplasms | Glioblastoma Multiforme | Gliosarcoma

United States
European Organisation for Research and Treatment...
Pfizer

Completed

Radiation Therapy and Temsirolimus or Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

Brain and Central Nervous System Tumors

United Kingdom, Switzerland, Belgium, Italy, Germany, France, Netherlands, Spain
Children's Cancer and Leukaemia Group

Unknown

Radiation Therapy and Tamoxifen in Treating Children With Newly Diagnosed Brain Stem Glioma

Brain and Central Nervous System Tumors

United Kingdom, Ireland
University College, London

Completed

Improving Surgical Outcomes in Patients With Low Grade Gliomas Using Advanced Pre- and Intra-operative MRI

Brain Neoplasms

United Kingdom
King's College Hospital NHS Trust
Ampersand Health Ltd; Neuroendocrine Cancer UK

Recruiting

Mobile Application to Collect PRO Data in NET Patients

Neuroendocrine Neoplasms (Tumours)

United Kingdom
Children's Cancer and Leukaemia Group

Unknown

Temozolomide and Radiation Therapy in Treating Young Patients With Pontine Glioma

Brain and Central Nervous System Tumors

Ireland, United Kingdom
Children's Cancer and Leukaemia Group

Completed

Combination Chemotherapy, Surgery or Radiation Therapy, and Peripheral Stem Cell Transplant in Treating Patients With Recurrent Medulloblastoma or Primitive Neuroectodermal and Pineal Tumors

Brain and Central Nervous System Tumors

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Unknown

High-Dose Methotrexate in Treating Young Patients With Residual Ependymoma

Brain and Central Nervous System Tumors

United Kingdom, Ireland
Nottingham University Hospitals NHS Trust
University of Nottingham; University of Bristol; Newcastle University; Newcastle-upon-Tyne... and other collaborators

Recruiting

Acceptance and Commitment Therapy for Neuro-Oncology Wellbeing (ACT NOW)

Quality of Life | Brain Tumors | Brain Tumor, Pediatric

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Completed

Reliability of Functional Outcome Measures in Neurofibromatosis 2

Neurofibromatosis 2

United Kingdom
King's College Hospital NHS Trust
King's College London; Erasmus Medical Center

Not yet recruiting

Mapping Molecular Markers of Brain Tumour Activity Using MRI

Glioma

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...
AstraZeneca

Completed

Intermittent Dosing Of Selumetinib In Childhood NF1 Associated Tumours (INSPECT)

Neurofibromatosis Type 1 | Optic Nerve Glioma | Plexiform Neurofibroma

United Kingdom
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas

Glioblastoma | Gliosarcoma | Anaplastic Astrocytoma | Central Nervous System Neoplasm | Spinal Cord Neoplasm

United States
Children's Cancer and Leukaemia Group

Completed

Combination Chemotherapy and Radiation Therapy in Treating Patients With Germ Cell Tumors in the Brain

Brain and Central Nervous System Tumors

United Kingdom, Ireland
HCA International Limited

Terminated

Investigating the Efficacy of Hair Sparing Radiotherapy Treatment to the Whole Brain. (SPARE)

Metastatic Brain Cancer

United Kingdom
University College, London
Cancer Research UK; The Brain Tumour Charity

Completed

Hippocampal Sparing Whole Brain Radiotherapy vs Conventional Whole Brain Radiotherapy in Patients With Brain Metastases (HIPPO)

Brain Metastases

United Kingdom
Nottingham University Hospitals NHS Trust

Completed

Upright Open MRI for Brain Imaging in Children - a Pilot Study (Heads-Up)

Brain Tumor

United Kingdom
King's College London

Recruiting

Intraoperative Hyperspectral Imaging for Fluorescence Guided Surgery in Low Grade Gliomas (Neuro-qFHSI)

Brain Tumor | Neurosurgery | Neuro-Oncology

United Kingdom
University of Nottingham
Nottingham University Hospital NHS Trust; Nottingham Hospitals Charity

Recruiting

Controlling Coordination After Childhood Cerebellar Cancer, a Pilot Study (5C-pilot)

Brain Cancer

United Kingdom
Children's Cancer and Leukaemia Group

Unknown

Combination Chemotherapy With or Without Radiation Therapy in Treating Children With Brain Tumors

Brain and Central Nervous System Tumors | Neuroblastoma

United Kingdom, Ireland

Clinical Trials on Central Nervous System Embryonal Neoplasm in United Kingdom

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