Clinical Trials on Chemical and Drug Induced Liver Injury

Total 8491 results

The Cleveland Clinic

Recruiting

Ethanol Induces Skeletal Muscle Autophagy

Alcoholic Liver Disease

United States
Rush University Medical Center
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Alcohol, Gut Leakiness, & Liver Disease

Alcoholic Liver Disease

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Targeting Self-regulatory Deficits Through Cognitive Remediation Intervention

Drug Use Disorders

United States
Cui Yimin

Unknown

Association of Genetic Polymorphisms With Docetaxel-based Chemotherapy Toxicities in Chinese Solid Tumor Patients

Pharmacokinetics | Drug-Related Side Effects and Adverse Reactions | Solid Tumors | Pharmacogenetics | Docetaxel

China
Bioprojet

Completed

Determination the Abuse Potential of Pitolisant in Healthy, Non-Dependent Recreational Stimulant Users

Healthy | Drug Abuse

Canada
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

The Effect of Fetal Gender on Maternal Substance Abuse Treatment

Pregnancy | Drug Dependence

United States
AstraZeneca

Withdrawn

Study in Healthy Recreational Polydrug Users to Measure the Abuse Potential of TC-5214 (TC-5214)

Healthy | Drug Abuse
Virginia Commonwealth University

Completed

CBT4CBT for Women in Residential Treatment for Substance Use Disorders

Substance Use Disorders | Substance Abuse | Drug Abuse | Drug Addiction | Drug Dependence | Drug Use Disorders | Substance Addiction

United States
Protherics Medicines Development Limited
Resonance Health

Recruiting

Retrospective Registry Study of Patients With Cancer Treated With High-dose Methotrexate

Acute Kidney Injury | Drug Toxicity

Spain, France, Italy
Lund University

Completed

PWID; Longitudinal S Aureus Colonization Pattern and the Impact on Infection Frequency by Regular Showers With Chlorhexidine

Intravenous Drug Abuse, S Aureus Colonization
NYU Langone Health
National Cancer Institute (NCI)

Completed

Chemotherapy and Amifostine in Treating Patients With Recurrent or Refractory Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific | Drug/Agent Toxicity by Tissue/Organ

United States
University Hospital, Rouen

Completed

Immunological and Viral Parameters in Patients Receiving Anti-epileptic Drugs (VIRIDAE)

Epilepsy | Drug Hypersensitivity Syndrome

France
University Hospital, Rouen

Terminated

Treatment of Hypersensitivity Syndrome (DRESS) With Tegeline® (Human Immunoglobulin) (DRESS2)

Drug Hypersensitivity

France
University Clinic Dr Dragisa Misovic-Dedinje

Unknown

S-adenosylmethionine Plus Choline in Treatment of Patients With Alcoholic Liver Disease

Alcoholic Liver Diseases

Serbia
University of Crete

Not yet recruiting

Inappropriate Polypharmacy in Elderly Patients in Primary Care and Deprescribing in Older Patients With Frailty

Frailty Syndrome | Polypharmacy | Deprescriptions | Medication Overuse
University of Colorado, Denver
Denver Health and Hospital Authority; Southern Colorado Harm Reduction Association and other collaborators

Not yet recruiting

Vending Machine Naloxone Distribution for Your Community (VENDY)

Harm Reduction | Naloxone | Opioid Overdose
International Center for Ethnobotanical Education...
University of Sao Paulo; Universidad Autonoma de Madrid; University Rovira i... and other collaborators

Recruiting

Preliminary Efficacy and Safety of Ibogaine in the Treatment of Methadone Detoxification

Opioid Dependence | Drug Dependence | Drug Use Disorders

Spain
University of California, San Diego

Recruiting

Guselkumab (Anti-IL 23 Monoclonal Antibody) for Alcohol Associated Liver Disease

Alcoholic Liver Disease

United States
University Hospital, Lille

Recruiting

Study of Alcohol-related Liver Disease in Europe (SALVE)

Alcoholic Liver Disease

France
Pusan National University Yangsan Hospital

Recruiting

Effect of Fermented Protaetia Brevitarsis Seulensis Powder on Alcohol-induced Liver Disease

Alcoholic Liver Disease

Korea, Republic of
Chuncheon Sacred Heart Hospital

Active, not recruiting

Gut Mycobiome Profile in Alcoholic Liver Disease.

Alcoholic Liver Disease

Korea, Republic of
University of California, Davis
National Institute on Alcohol Abuse and Alcoholism (NIAAA); University of Colorado... and other collaborators

Completed

Effects of SAMe in Patients With Alcoholic Liver Disease

Liver Disease, Alcoholic

United States
Erasme University Hospital

Completed

Role of CCL2 in Alcoholic Liver Diseases

Alcoholic Liver Disease
Zhejiang University

Completed

Study Comparing Conventional and Fast Track Multi-Discipline Treatment Interventions for Colorectal Cancer

Quality of Life | Complications | Adverse Drug Event | Length of Stay | Hospital Costs

China
Universitaire Ziekenhuizen KU Leuven

Completed

Exploratory Propofol Dose Finding Study In Neonates (NEOPROP)

Adverse Reaction to Drug | Neonatal Disorder

Belgium
UCB Pharma

Completed

Levetiracetam in the Treatment of Neuroleptic-induced Tardive Dyskinesia

Dyskinesia, Medication-induced

Belgium, Bulgaria
Oslo University Hospital

Active, not recruiting

Effects of Switching From Racemic Methadone to R-methadone on QTc Intervals (MePhaCard)

Drug Effect | Adverse Drug Effect | Heart Arrhythmia

Norway
The Cleveland Clinic

Recruiting

Comparison of ALD, NASH, and Healthy Control Patients

ALD - Alcoholic Liver Disease

United States
Nationwide Children's Hospital

Recruiting

Evaluation of a Novel Intervention to Prevent Polysubstance Overdoses Involving Illicit Stimulants

Harm Reduction | Opiate Overdose | Fentanyl Overdose

United States
Nationwide Children's Hospital

Recruiting

Evaluating an Intervention to Prevent Overdoses in Rural and Urban Counties

Harm Reduction | Opiate Overdose | Fentanyl Overdose

United States
National Development and Research Institutes, Inc.
New York University; Rhode Island Hospital; Drexel University; Brandeis University

Recruiting

Overdose Risk Management and Naloxone

Opioid Use

United States
National Institute on Drug Abuse (NIDA)

Completed

Developing Field Tools for Real-Time Assessment of Exposure to Psychosocial Stress and Drug Use in an Outpatient Treatment Population

Stress | Drug Abuse

United States
Ankara University

Completed

Local Anesthesia Impact on Dental Sedation

Sedative Overdose

Turkey
University of Pennsylvania

Active, not recruiting

Stimulant Overdose in the Medicaid Population: Who is at Risk, and When Are They at Risk

Stimulant Overdose

United States
Parc de Salut Mar

Completed

Synchronous Effect of Anesthetics on fMRI, EEG and Clinical Responses

Sedative Overdose

Spain
University of Washington
U.S. National Science Foundation

Completed

Naloxone Auto-injection in Healthy Volunteers

Overdose Antidote

United States
ART Fertility Clinics LLC

Terminated

Measurement of Midazolam Levels in Follicular Fluid

Midazolam Overdose

United Arab Emirates
Cambridge University Hospitals NHS Foundation Trust
AstraZeneca; University of Cambridge

Terminated

A Study of the Pharmacokinetic and Pharmacodynamic Responses in Healthy and Altered Human Cardiovascular Systems (PRIME)

Drug-Related Side Effects and Adverse Reactions | Cardiovascular System Disease

United Kingdom
University of Pennsylvania

Completed

Use of Virtual Reality for Overdose Management Educational Trainings

Virtual Reality | Drug Overdose

United States
Universidad Miguel Hernandez de Elche
Fondo de Investigacion Sanitaria; Fundación para el Fomento de la Investigación... and other collaborators

Completed

Consequences of Doing What Should Not be Done in Primary Care (SOBRINA)

Overdose | Adverse Event

Spain
Egetis Therapeutics
University of Edinburgh; NHS Lothian

Completed

PP100-01 (Calmangafodipir) for Overdose of Paracetamol (POP)

Paracetamol Overdose

United Kingdom
Eisai Inc.

Completed

Abuse Potential of Single Doses of Lorcaserin in Healthy Recreational Polydrug Users

Healthy | Drug Abuse

Canada
Cui Yimin

Unknown

Association of Genetic Polymorphisms With Capecitabine-based Chemotherapy Toxicities in Chinese Solid Tumor Patients

Solid Tumor | Pharmacokinetics | Drug-Related Side Effects and Adverse Reactions | Capecitabine | Pharmacogenetics

China
Cumberland Pharmaceuticals

Terminated

Safety and Efficacy Study of a New Formulation of Acetylcysteine Injection

Acetaminophen Overdose

United States
University Hospitals Cleveland Medical Center

Completed

Inpatient Penicillin Allergy Delabeling Study

Penicillin Allergy | Penicillin Sensitivity | Penicillin Reaction | Penicillin Intolerance

United States
St. Louis University

Completed

Assessment of Immediate Adverse Reactions From Dotarem in Children Under 2 Years of Age

Adverse Reaction to Drug | Allergic Reaction to Contrast Media

United States
Norwegian University of Science and Technology
St. Olavs Hospital

Completed

Pharmacodynamics and Arteriovenous Differences of Naloxone in Healthy Participants Exposed to an Opioid (OPI-15-001)

Drug Overdose

Norway
Kevin Winthrop
Medical University of South Carolina; Mayo Clinic; University of Washington; National... and other collaborators

Not yet recruiting

Prevention of Ototoxicity in NTM Patients Treated With IV Amikacin

Ototoxicity, Drug-Induced

United States
State University of New York at Buffalo
Hellenic Scientific Society for the Study of AIDS, Sexually Transmitted and...

Completed

Telemedicine and Social Media for People Who Inject Drugs (PWID) in Greece

Telemedicine | Social Media | Drug Abuse, Intravenous | Internet

Greece
New York Presbyterian Hospital
University of Wisconsin, Madison

Unknown

Using Addiction Comprehensive Health Enhancement Support System (ACHESS) in an Alcoholic Liver Disease Population

Liver Diseases, Alcoholic

United States

Clinical Trials on Chemical and Drug Induced Liver Injury

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Colombia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations