Clinical Trials on Chemotherapeutic Toxicity in United States

Total 271 results

Washington University School of Medicine
St. Jude Children's Research Hospital

Completed

Translating ECHOS2 Into an mHealth Platform (ECHOS2)

Childhood Cancer | Pediatric Cancer | Cardiac Toxicity

United States
University of California, San Francisco

Active, not recruiting

Predicting the Risk of Failure in Patients Undergoing Radiation Therapy for Localized Prostate Cancer

Prostate Cancer | Radiation Toxicity

United States
Children's Hospital Los Angeles
National Cancer Institute (NCI)

Completed

N2003-01: Irinotecan, Temozolomide, and Cefixime in Treating Young Patients With Recurrent or Resistant Neuroblastoma

Diarrhea | Neuroblastoma | Drug/Agent Toxicity by Tissue/Organ

United States
University of Colorado, Denver

Completed

13-Cis Retinoic Acid With or Without Vitamin E for Prevention of Lung Cancer (13-Cis)

Lung Cancer | Drug Toxicity

United States
M.D. Anderson Cancer Center
Alere San Diego

Unknown

Effectiveness of Using Biomarkers to Detect and Identify Cardiotoxicity and Describe Treatment (PREDICT)

Unspecified Adult Solid Tumor, Protocol Specific | Cardiac Toxicity

United States
National Cancer Institute (NCI)

Completed

Oblimersen Plus Combination Chemotherapy and Dexrazoxane in Treating Children and Adolescents With Relapsed or Refractory Solid Tumors

Unspecified Childhood Solid Tumor, Protocol Specific | Cardiac Toxicity

United States
Virginia Commonwealth University
National Cancer Institute (NCI)

Completed

High-Dose Cytarabine Plus Deoxycytidine in Treating With Acute Myelogenous Leukemia or Other Hematologic Malignancies

Lymphoma | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm | Drug/Agent Toxicity by Tissue/Organ

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Compliance to Vaginal Dilation Therapy in Patients Who Have Undergone Radiation Therapy For Stage IB, Stage IIA, Stage IIB, Stage IIIA, or Stage IIIB Cervical Cancer or Stage IA, Stage IB, Stage IIA, or Stage IIB Endometrial Cancer

Cervical Cancer | Endometrial Cancer | Radiation Toxicity | Sexuality and Reproductive Issues

United States
Thomas Jefferson University
Wyeth is now a wholly owned subsidiary of Pfizer

Withdrawn

Switching From One Type of Anti-rejection Drug (Tacrolimus or Cyclosporine) to Another (Sirolimus) Approximately 90-180 Days After Liver Transplantation

Neurotoxicity | Renal Toxicity | Side Effects of Calcineurin Inhibitors | Hepatic Fibrosis on Biopsy | Post Transplant Diabetes

United States
National Cancer Institute (NCI)

Completed

Monoclonal Antibody Therapy in Treating Patients With Leukemia

Lymphoma | Radiation Toxicity

United States
Tufts Medical Center
Merck Sharp & Dohme LLC

Active, not recruiting

Letermovir Use in Heart Transplant Recipients

Neutropenia | Cytomegalovirus Infections | Cytomegalovirus Disease | Heart Transplant Infection | Antiviral Toxicity

United States
Vanderbilt University Medical Center
National Cancer Institute (NCI)

Completed

Kidney Dysfunction in Children and Young Adults Who Have Received Methotrexate for Acute Lymphoblastic Leukemia

Leukemia | Renal Toxicity

United States
Cedars-Sinai Medical Center
Jarrow Formulas Inc

Not yet recruiting

SAMe in Prevention of Oxaliplatin-associated Liver Injury

Colorectal Cancer | Liver Metastases | Liver Metastasis Colon Cancer | Liver Injury | Sinusoidal Obstruction Syndrome | 5-Fluorouracil Toxicity | Liver Toxicity, Chemically-Induced

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

L-Arginine Supplementation With or Without Enzyme Inhibitors Treating Erectile Function of Prostate Cancer Survivors

Prostate Cancer | Radiation Toxicity | Male Erectile Disorder

United States
Queen Mary University of London

Completed

Bleomycin, Etoposide, and Cisplatin in Treating Patients With Metastatic Germ Cell Cancer of the Testicles

Testicular Germ Cell Tumor | Drug/Agent Toxicity by Tissue/Organ

United Kingdom
Abramson Cancer Center of the University of Pennsylvania
National Cancer Institute (NCI)

Terminated

Flaxseed Supplement in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Undergoing Chemotherapy and Radiation Therapy

Lung Cancer | Radiation Toxicity

United States
Tufts Medical Center

Recruiting

Letermovir for Secondary Prophylaxis in Solid Organ Transplant Recipients

Neutropenia | Cytomegalovirus Infections | Infection in Solid Organ Transplant Recipients | Antiviral Toxicity

United States
Case Comprehensive Cancer Center

Completed

Acute Side Effects in Patients Who Are Undergoing Stereotactic Radiosurgery for Brain Tumors or Other Brain Disorders

Brain and Central Nervous System Tumors | Metastatic Cancer | Radiation Toxicity

United States
Wellstat Therapeutics

Completed

Triacetyluridine and Fluorouracil Compared With Gemcitabine in Treating Patients With Unresectable Locally Advanced, or Metastatic Pancreatic Cancer

Pancreatic Cancer | Drug/Agent Toxicity by Tissue/Organ

United States, Canada
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Pyridoxine in Preventing Hand-Foot Syndrome in Patients Who Are Receiving Liposomal Doxorubicin for Cancer

Breast Cancer | Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cavity Cancer | Endometrial Cancer | Drug/Agent Toxicity by Tissue/Organ

United States
Imperial College London

Completed

Predictive Model of Therapy Outcomes in Breast Cancer Patients

Toxicity From Medication (Endocrine Treatment and Chemotherapy) Given for Breast Cancer Treatment.

United Kingdom
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Pyridoxine and Topical Urea/Lactic Acid-Based Cream in Preventing Hand-Foot Syndrome in Patients Receiving Capecitabine for Breast Cancer or Other Cancer

Breast Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Drug/Agent Toxicity by Tissue/Organ

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Genetic Susceptibility to Radiation-Induced Skin Reactions in Racial/Ethnic Groups of Patients With Breast Cancer

Pain | Breast Cancer | Fatigue | Skin Abnormalities | Radiation Toxicity | Cognitive Ability, General | Psychosocial Deprivation

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Standard Versus Intensity-Modulated Pelvic Radiation Therapy in Treating Patients With Endometrial or Cervical Cancer

Cervical Cancer | Endometrial Cancer | Radiation Toxicity | Perioperative/Postoperative Complications | Gastrointestinal Complications | Urinary Complications | Urinary Tract Toxicity

United States, Canada, Singapore, Hong Kong
Scripps Health

Completed

Amifostine Followed by High Dose Chemotherapy in Treating Patients With Hematologic Cancer or Solid Tumors

Lymphoma | Breast Cancer | Ovarian Cancer | Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Drug/Agent Toxicity by Tissue/Organ

United States
Memorial Sloan Kettering Cancer Center

Recruiting

Clindamycin and Triamcinolone in People With Glioblastoma to Prevent Skin-Related Side Effects of Tumor Treating Fields

Glioblastoma | Recurrent Glioblastoma | Skin Toxicity

United States
Mayo Clinic
University of Toronto

Completed

A Comparison of Infection Rates Between Two Surgical Sites

Surgical Site Infection | Ototoxicity | Corneal Toxicity

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy and Cisplatin With or Without Amifostine for Patients With Stage IIIB or IVA Cervical Cancer

Cervical Cancer | Radiation Toxicity

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Phase II Studies Of Donepezil And Ginkgo Biloba In Irradiated Brain Tumor

Brain and Central Nervous System Tumors | Radiation Toxicity

United States
University of South Florida
National Cancer Institute (NCI)

Terminated

Triptorelin for Preserving Ovarian Function in Premenopausal Women Receiving Chemotherapy for Early-Stage Breast Cancer

Breast Cancer | Drug Toxicity | Hormone Changes

United States
The Cleveland Clinic

Unknown

Combination Chemotherapy Plus Amifostine in Treating Patients With Advanced Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Drug/Agent Toxicity by Tissue/Organ

United States
Richard Dart, MD, PhD
Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division

Recruiting

Evaluation of the Efficacy of Fomepizole in the Treatment of Acetaminophen Overdose

Liver Failure | Drug Overdose | Acetaminophen Overdose | Acetaminophen | Drug-induced Liver Injury | Acetaminophen Poisoning | Liver Toxicity

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Alkaline Water in Reducing Skin Toxicity in Women With Breast Cancer Undergoing Radiation Therapy

Stage I Breast Cancer | Radiation Toxicity | Stage IV Breast Cancer | Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer | Recurrent Breast Cancer

United States
Royal Marsden NHS Foundation Trust

Unknown

Parotid-Sparing Intensity-Modulated Radiation Therapy Compared With Conventional Radiation Therapy in Treating Patients With Oropharyngeal or Hypopharyngeal Cancer Who Are at High Risk of Radiation-Induced Xerostomia

Head and Neck Cancer | Xerostomia | Radiation Toxicity

United Kingdom
University of Edinburgh
NHS Lothian

Completed

Thermal Testing in Bone Pain (TiBoP) (TiBoP)

Pain | Toxicity Due to Radiotherapy | Cancer Induced Bone Pain | Secondary Malignant Neoplasm of Bone

United Kingdom
National Cancer Institute (NCI)

Unknown

Iseganan Hydrochloride in Preventing Oral Mucositis in Patients Who Are Undergoing Radiation Therapy for Head and Neck Cancer

Head and Neck Cancer | Radiation Toxicity | Oral Complications of Radiation Therapy

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Doxorubicin and Cyclophosphamide Followed By Trastuzumab, Paclitaxel, and Lapatinib in Treating Patients With Early-Stage HER2-Positive Breast Cancer That Has Been Removed By Surgery

Breast Cancer | Cardiac Toxicity

United States
Henry Ford Health System
Helen L. Kay Charitable Trust

Completed

Prevention Using Exercise Rehabilitation to Offset Cardiac Toxicities Induced Via Chemotherapy (HF-PROACTIVE)

Leukemia | Breast Cancer | Gastric Cancer | Doxorubicin Induced Cardiomyopathy

United States
The University of Texas Health Science Center at...

Recruiting

Financial Toxicity and Quality of Life in Patients With TGCT

Testicular Neoplasm

United States
Margaret Liotta

Recruiting

An Enhanced Vaginal Dilator to Reduce Radiation-Induced Vaginal Stenosis

Cervical Cancer | Endometrial Cancer | Radiation Toxicity | Vaginal Stricture

United States
M.D. Anderson Cancer Center
Massachusetts General Hospital

Completed

Early Detection and Prediction of Chemotherapy Induced Cardiac Toxicity in Breast Cancer Patients

Breast Cancer

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Cisplatin and Paclitaxel in Treating Patients With Stage IIB, Stage IIC, Stage III, or Stage IV Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cavity Cancer

Ovarian Clear Cell Cystadenocarcinoma | Ovarian Serous Cystadenocarcinoma | Fallopian Tube Carcinoma | Endometrial Adenocarcinoma | Primary Peritoneal Carcinoma | Malignant Ovarian Mixed Epithelial Tumor | Ovarian Brenner Tumor | Ovarian Mucinous Cystadenocarcinoma | Undifferentiated Ovarian Carcinoma | Gastrointestinal Complication and other conditions

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Terminated

Amifostine and Melphalan in Treating Patients With Primary Systemic Amyloidosis Who Are Undergoing Peripheral Stem Cell Transplantation

Multiple Myeloma and Plasma Cell Neoplasm | Drug/Agent Toxicity by Tissue/Organ

United States
Case Comprehensive Cancer Center

Completed

Low-Residue Diet in Treating Diarrhea in Patients Receiving Pelvic Radiation Therapy.

Sarcoma | Cervical Cancer | Diarrhea | Prostate Cancer | Radiation Toxicity

United States
Avera McKennan Hospital & University Health Center

Terminated

Use of Metformin to Reduce Cardiac Toxicity in Breast Cancer

Breast Cancer | Breast Tumors

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Terminated

Selenomethionine in Reducing Mucositis in Patients With Locally Advanced Head and Neck Cancer Who Are Receiving Cisplatin and Radiation Therapy

Mucositis | Xerostomia | Radiation Toxicity | Stage III Squamous Cell Carcinoma of the Hypopharynx | Stage III Squamous Cell Carcinoma of the Larynx | Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage III Squamous Cell Carcinoma of the Nasopharynx | Stage III Squamous Cell Carcinoma... and other conditions

United States, New Zealand
Vanderbilt University
National Cancer Institute (NCI)

Completed

Side Effects Involving the Heart in Women With Breast Cancer Receiving Doxorubicin and Trastuzumab (PACE in BC)

Breast Cancer | Cardiac Toxicity | Cardiovascular Complications

United States
Rutgers, The State University of New Jersey

Recruiting

Statins for Reduction of Cardiac Toxicity in Patients Receiving HER2 Targeted

Cardiac Toxicity | Early-stage Breast Cancer

United States
National Institute of Diabetes and Digestive and...

Recruiting

Search for New Methods to Detect Acute Renal Failure

Kidney Failure, Chronic | Healthy Volunteers | Kidney Failure | Kidney Disease | Renal Tubular Toxicity

United States
Indiana University

Recruiting

Pre-Rehabilitation for Female Patients Undergoing Pelvic Radiotherapy

Sexual Dysfunction | Pelvic Pain | Radiation Toxicity | Dyspareunia

United States

Clinical Trials on Chemotherapeutic Toxicity in United States

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