Clinical Trials on Chemotherapeutic Agent Toxicity

Total 1098 results

Fundació Institut de Recerca de l'Hospital de la...

Recruiting

Influence of Timing PTCy in AlloSCT

Cyclophosphamide Toxicity | Allogenic Haematopoetic Transplantation

Spain
Centre Hospitalier Universitaire, Amiens

Recruiting

Impact of a Multidisciplinary Consultation Program on Drug Adherence in First Oral Anticancer Treatment (IMPAM)

Multidisciplinary Consultation Program | Adherence to Oral Anticancer Treatment | Drug Related Toxicity | Securing Medication Management

France
Military Institute of Medicine, Poland

Completed

Compliance of Initial Empiric Antimicrobial Therapy

Anti-Infective Agents

Poland
Peking Union Medical College Hospital

Recruiting

Anesthesia Neurodevelopmental Impact in Congenital Scoliosis Children

General Anesthetics Toxicity

China
University Medical Center Goettingen

Recruiting

Efficacy of Structured SOcial COnsultation and Support in Reducing the FINancial Burden of Radiotherapy (SOCOFIN-1)

Financial Toxicity

Germany
Sohag University

Not yet recruiting

Evaluation of the Role of Poisoning Severity Score, Serum Procalcitonin and C-reactive Protein in Acute Hydrocarbon Intoxicated Cases Admitted to the Poison Control Center Ain Shams University Hospitals

Acute Hydrocarbon Toxicity

Egypt
Thomas Jefferson University

Active, not recruiting

Ropivacaine Pharmacokinetics in ESP Blocks

Pain | Quality of Recovery | Local Anesthetic Systemic Toxicity

United States
Montefiore Medical Center

Terminated

Mechanisms and Treatment of Chronic Allograft Injury (CAI) Due to Calcineurin Inhibitor (CNI) Toxicity

Chronic Allograft Injury | Calcineurin Inhibitor Toxicity

United States
National Institutes of Health Clinical Center (CC)

Completed

Probiotic Ingestion and Isoagglutinin Titers

Isoagglutinin-Mediated Hemolysis | Probiotic Toxicity

United States
Ain Shams University

Active, not recruiting

A Comparative Study Between Arm Intravenous Regional Anesthesia Versus Forearm Intravenous Regional Anesthesia in Patients Undergoing Hand and Wrist Surgery

Hand Injury Wrist | Intravenous Anesthetic Agent Overdose

Egypt
Heba Allah Ali Abd El-Halim Mabrouk
Tanta University

Unknown

Alpha Lipoic Acid as an Adjuvant Treatment in Acute Phosphide Poisoning (ALA)

Toxicity
Janssen Korea, Ltd., Korea

Completed

A Study to Evaluate Treatment Adherence in Schizophrenia With Long Acting Risperidone Microspheres (e-STAR)

Mental Disorders | Schizophrenia | Tranquilizing Agents | Therapeutic Uses | Physiological Effects of Drugs | Psychotropic Drugs | Antipsychotic Agents
University of California, Davis
Veloxis Pharmaceuticals

Completed

A Pilot Study to Evaluate Impact on Neurological Side Effects (Cognition, Memory, and Tremor) in Elderly (Age>65) Patients

Toxicity | Neurotoxicity | Kidney Transplant; Complications | Drug Toxicity

United States
Luye Pharma Group Ltd.

Completed

Study to Evaluate the PK Profiles of LY03010 in Patients With Schizophrenia or Schizoaffective Disorder

Mental Disorders | Psychotic Disorders | Mood Disorders | Schizophrenia | Schizophrenia Spectrum and Other Psychotic Disorders | Molecular Mechanisms of Pharmacological Action | Tranquilizing Agents | Physiological Effects of Drugs | Psychotropic Drugs | Antipsychotic Agents | Neurotransmitter Agents | Central...

United States
Osprey Medical, Inc

Terminated

Contrast Media Reduction and Removal in Patients With Chronic Kidney Disease (CKD) (PRESERV)

Radiographic Contrast Agent Nephropathy

United States, Germany
Radboud University Medical Center

Not yet recruiting

Model Informed preciSion doSIng tO iNdividualise and Optimize Pharmacotherapeutic Treatment (MISSION)

Pharmacokinetics | Tacrolimus | Area Under Curve | Immunosuppressive Agents | Mycophenolic Acid
Onconic Therapeutics Inc.

Completed

Compare Pharmacokinetics and Safety of JP-1366 Between Korean and Caucasian

Anti-Ulcer Agents

Korea, Republic of
Annelies Verbon
University Hospital, Geneva; Erasmus Medical Center; Uppsala University Hospital and other collaborators

Unknown

A Digital Antimicrobial Stewardship Smartphone Application to Combat AMR: the AB-assistant (AB-assistant)

Mobile Applications | Quality Improvement | Anti-Infective Agents | Antimicrobial Stewardship

Canada, Netherlands, Sweden, Switzerland
Dr. Krupa NC

Completed

Anticaries Effect of Xylitol,Probiotic and Chlorhexidine Mouth Rinses Among Individuals at High Risk (AEXPC)

Cariostatic Agents | Mouthwashes

India
Mayo Clinic

Recruiting

Comparative Study of Two Topical Anesthetics Prior to Fractional Nonablative Laser Treatment of the Face

Anesthesia, Local | Photodamaged Skin | Topical and Infiltration Anesthetic Toxicity

United States
National Cancer Institute, Naples

Recruiting

Development and Validation of a Tool for Patient-reported Assessment of Cancer-related Financial Toxicity in Italy (PROFTC-I)

Cancer

Italy
University Medical Center Groningen

Recruiting

Investigating Cardiovascular Adverse Events Related to Cancer Treatment (InvestiCAT)

Toxicity Due to Chemotherapy | Cancer, Treatment-Related | Cardiovascular Morbidity

Netherlands
Jong Hoon Lee

Unknown

Two-week Course Versus Conventionally Fractionated Chemoradiotherapy in Rectal Cancer

Recurrence | Toxicity | Response to Toxin

Korea, Republic of
Żelazna Medical Centre, LLC
Laboratory of Genetics and Human Genomics, University of Gdańsk

Completed

Genetic Aspects of Vaginal Aging

Genitourinary Agents

Poland
University of Geneva, Switzerland
University Hospital, Geneva

Recruiting

The OPTIMAL TDM Study: Determining Optimal Beta-lactam Plasma Concentrations Through Therapeutic Drug Monitoring (OPTIMAL TDM)

Efficacy | Toxicity | Beta-lactam Antibiotics | Therapeutic Drug Monitoring | Ceftazidime | Amoxicillin | Meropenem | Imipenem | Piperacillin | Flucloxacillin | Cefepime

Switzerland
Harvard School of Public Health (HSPH)
National Institute on Drug Abuse (NIDA); National Institute on Alcohol Abuse... and other collaborators

Recruiting

Surveillance Monitoring for ART Toxicities Study in HIV Uninfected Children Born to HIV Infected Women (SMARTT)

Antiretroviral Toxicity

United States, Puerto Rico
Hadassah Medical Organization

Unknown

Fertility Preservation by Ovarian and Oocyte Cryopreservation (HFPP)

Female Patients Aged 5-35 Prior to Systemic Chemotherapy | With Significant Risk of Ovarian Toxicity

Israel
UCB Pharma

Completed

Facial Thermography Study of Levocetirizine Versus Cetirizine

Anti-allergic Agents
Sohag University

Not yet recruiting

Evaluation of High Dose Methotrexate Toxicity

Methotrexate Toxicity
Duke University
United States Navy

Enrolling by invitation

Effects of Pre-dive Ketone Food Products on Latency to CNS Oxygen Toxicity (Aim 2)

Oxygen Toxicity

United States
Duke University
United States Navy

Enrolling by invitation

Effects of Pre-dive Ketone Food Products on Latency to CNS Oxygen Toxicity (Aim 1)

Oxygen Toxicity

United States
Hopital Louis Pradel

Unknown

Diagnosis Accuracy of Abdominal Compression and Hemoconcentration to Detect Diuretic Induced Fluid Removal Intolerance.

Fluid Overload | Hypovolemia | Diuretic Toxicity

France
Assaf-Harofeh Medical Center

Completed

Hyperbaric Oxygen Therapy Effects on Pulmonary Functions (PulmHBOT)

Hyperoxia | Oxygen Toxicity

Israel
University of Louisville

Withdrawn

The Acute Cardiovascular Effects of Nicotine in E-cigarettes (ACE) Study (ACE)

Nicotine | Cigarette Smoking Toxicity | Acute Cardiovascular Disease

United States
Luye Pharma Group Ltd.

Completed

Relative Bioavailability of LY03010 Compared to Listed Drug

Mental Disorders | Psychotic Disorders | Mood Disorders | Schizophrenia | Molecular Mechanisms of Pharmacological Action | Tranquilizing Agents | Physiological Effects of Drugs | Psychotropic Drugs | Antipsychotic Agents | Central Nervous System Depressants | Neurotransmitter Agents | Schizophrenia Spectrum

United States
Zonguldak Bulent Ecevit University

Completed

AGC Mode vs Minimal Flow in Breast Surgery

Breast Diseases | Anesthesia; Functional | Volatil Agent Consumption | Automatic End-tidal Controlled Anesthesia

Turkey
Jeil Pharmaceutical Co., Ltd.

Completed

Clinical Trial to Investigate the Safety, Tolerability and Pharmacokinetics and Pharmacodynamics of JP-1366 Oral Administration in Healthy Male Subjects

Anti-Ulcer Agents

Korea, Republic of
King Hussein Cancer Center

Withdrawn

Radiation Oncology Mobile Application (γ-App)

Head and Neck Cancer | Radiation Toxicity

Jordan
Vanderbilt University Medical Center
National Institute of General Medical Sciences (NIGMS)

Completed

Pharmacogenomics of the Variability in the In Vivo Response to Glucocorticoids

Glucose Intolerance | Glucocorticoids Toxicity

United States
University Hospital, Geneva

Unknown

APAP Hepatotoxicity After Therapeutic Doses

Malnutrition | Paracetamol Toxicity | Hepatotoxicity

Switzerland
RWTH Aachen University
Technion, Israel Institute of Technology

Unknown

Optimized Multi-modality Machine Learning Approach During Cardio-toxic Chemotherapy to Predict Arising Heart Failure (MERMAID)

Toxicity Due to Chemotherapy

Germany
Dartmouth-Hitchcock Medical Center

Completed

A Survey of Financial Toxicity in Rural Cancer Patients

Financial Toxicity

United States
Attikon Hospital

Completed

Echocardiography and Spinal Induced Hypotension.

Spinal Anesthetic Toxicity

Greece
University of Witwatersrand, South Africa

Terminated

Differences Between Stavudine and Tenofovir Each Combined With Lamivudine and Efavirenz in SA HIV-infected Patients (CHRU01)

Metabolic Complications | Mitochondrial Toxicity

South Africa
University Health Network, Toronto
University College London Hospitals; Brigham and Women's Hospital; University... and other collaborators

Recruiting

The STOP-MED CTRCD Trial (STOP-MED)

Heart Failure | Cancer | Cardiotoxicity | Cardiac Toxicity | Antineoplastics Toxicity

Canada, United States, United Kingdom, Australia
Centro Hospitalar do Porto

Completed

Propofol Pharmacokinetics and Pharmacodynamics Modelling

Intravenous Anesthetic Agent Overdose

Portugal
RenJi Hospital
BeiGene; Huidu Shanghai Medical Sciences Ltd

Recruiting

Safety and Efficacy Study of Tislelizumab in Combination With BCG in HR-NMIBC Patients (TACBIN-01) (TACBIN-01)

Urologic Neoplasms | Urogenital Neoplasms | Urinary Bladder Diseases | Urinary Bladder Neoplasms | Antineoplastic Agents | Tislelizumab Antineoplastic Agents, Immunological

China
University of South Alabama
University of Alabama at Birmingham; University of Nevada, Las Vegas; Rutgers... and other collaborators

Recruiting

Protective Effect of Nicotinamide Riboside Against Acetaminophen Toxicity

Drug Toxicity

United States
Supriya Mohile
National Cancer Institute (NCI); University of Chicago; City of Hope National...

Completed

Geriatric Assessment Intervention for Reducing Toxicity in Older Patients With Advanced Cancer

Lymphoma | Toxicity | Adult Solid Neoplasm

United States
Karabuk University

Completed

Investigation of Wet Cupping Therapy on Heavy Metal Levels of Steel Industry Workers

Heavy Metal Toxicity

Turkey

Clinical Trials on Chemotherapeutic Agent Toxicity

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