Clinical Trials on Cholangiocarcinoma, Perihilar

Total 763 results

National Cancer Center, Korea
Boston Scientific Corporation

Not yet recruiting

Intraductal Radiofrequency Thermoablation and Radiotherapy Combined Treatment for Extrahepatic Cholangiocarcinoma

Radiotherapy | Biliary Tract Carcinoma | Radio-frequency Ablation
AnHeart Therapeutics Inc.

Recruiting

IDH1 Inhibitor AB-218 in Patients With Advanced IDH1 Mutant Cholangiocarcinoma and Other Solid Tumor

Cholangiocarcinoma With IDH1 Mutation | Solid Tumors With IDH1 Mutation

China
National Cancer Institute (NCI)

Suspended

Testing Olaparib and AZD6738 in IDH1 and IDH2 Mutant Tumors

Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Refractory Cholangiocarcinoma

United States
Fudan University

Unknown

Clinical Trial of Adjuvant Chemotherapy Followed by Concurrent Chemoradiotherapy Compared With Adjuvant Chemotherapy Alone in Patients With Gallbladder Carcinoma and Extrahepatic Cholangiocarcinoma

Malignant Neoplasm Other Gallbladder/Extrahepatic Bile Duct

China
Sun Yat-sen University

Unknown

Preoperative Biliary Drainage for Resectable Hilar Cholangiocarcinoma

Surgery | Cholangiocarcinoma | Drainage

China
Geneplus-Beijing Co. Ltd.
Eastern Hepatobiliary Surgery Hospital

Withdrawn

Therapeutic ResistAnce and Clonal Evolution Assessed With Liquid Biopsy in ICIs Treated Primary Liver Cancer

Hepatocellular Carcinoma | Primary Liver Cancer | Intrahepatic Cholangiocarcinoma | Combined Hepatocellular-cholangiocarcinoma

China
Ronald DeMatteo, M.D.

Recruiting

Infusion System for Hepatic Cancer

Intrahepatic Cholangiocarcinoma | Colorectal Cancer Metastatic to Liver

United States
Michael Lidsky, M.D.

Withdrawn

Hepatic Artery Infusion (HAI) Program at Duke University

Intrahepatic Cholangiocarcinoma | Liver Cancer | Metastatic Colon Cancer
Zhejiang Cancer Hospital

Recruiting

GOT Applied as Neoadjuvant Regimen for Patients of Resectable ICC With High-risk Factors of Recurrence (GOT)

Intrahepatic Cholangiocarcinoma

China
Kinnate Biopharma

Active, not recruiting

A Study to Evaluate KIN-3248 in Participants With Advanced Tumors Harboring FGFR2 and//or FGFR3 Gene Alterations

Intrahepatic Cholangiocarcinoma | Urothelial Carcinoma | Solid Tumor, Adult

United States, Korea, Republic of, Taiwan, China, Denmark, Spain
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

Study of Irinotecan Liposome Injection in Patients With Advanced Biliary Tract Cancer

Intrahepatic Cholangiocarcinoma | Gallbladder Carcinoma | Advanced Biliary Tract Cancer | Extrahepatic Cholangiocarcinoma

China
Kaohsiung Medical University Chung-Ho Memorial...
Kaohsiung Medical University

Recruiting

Evaluation the Palliative Effects of Colchicine on Primary Hepatic Malignant Tumors Unable to Receive Curative Treatment

Cholangiocarcinoma, Intrahepatic | Hepatocellular Carcinoma Stage IIIB | Cholangiocarcinoma; With Hepatocellular Carcinoma | Hepatocellular Carcinoma Stage IV

Taiwan
307 Hospital of PLA
Changhai Hospital; The Affiliated Nanjing Drum Tower Hospital of Nanjing University...

Unknown

Radioactive Stents for Treatment of Unresectable Biliary Tract Cancer

Intrahepatic Cholangiocarcinoma | Biliary Obstruction | Cholangiocarcinoma of the Extrahepatic Bile Duct | Ampullary Carcinoma

China
Fudan University

Recruiting

Adjuvant PD-1 Antibody in Combination With Capecitabine for Patients With ICC at High-Risk of Postoperative Recurrence

Cholangiocarcinoma, Intrahepatic

China
The First Affiliated Hospital with Nanjing Medical...
Jiangsu Hengrui Pharmaceutical Co., Ltd.

Recruiting

Neoadjuvant Therapy of HAIC（GEMOX） Combined With Adebrelimab and Lenvatinib for Resectable Intrahepatic Cholangiocarcinoma With High-risk Recurrence Factors

Intrahepatic Cholangiocarcinoma

China
Tianjin Medical University Cancer Institute and...

Recruiting

Tislelizumab Combined With Lenvatinib and GEMOX Versus Tislelizumab Combined With GEMOX in Conversion Therapy of ICC and GBC.

Potentially Resectable Locally Advanced Intrahepatic Cholangiocarcinoma and Gallbladder Cancer

China
Institut für Klinische Krebsforschung IKF GmbH...
Incyte Biosciences International Sàrl

Recruiting

Pemigatinib After Curative Local Therapy in Advanced iCCA With FGFR2 Fusion/Rearrangements

Intrahepatic Cholangiocarcinoma | FGFR2 Gene Mutation | FGFR2 Gene Translocation | FGFR2 Gene Rearrangement

Germany
Tianjin Medical University Cancer Institute and...

Recruiting

Durvalumab Combined With GemCis Neoadjuvant Therapy of Resectable Intrahepatic Cholangiocarcinoma With High Recurrence Risk

Intrahepatic Cholangiocarcinoma | Durvalumab | Gemcis

China
Florida Hospital Tampa Bay Division

Enrolling by invitation

Tampa Associating Microwave Liver Ablation With Portal Vein Ligation for Staged Hepatectomy (TAMLAPS) (TAMLAPS)

Hepatocellular Carcinoma | Liver Tumor | Hilar Cholangiocarcinoma | Liver Cancer

United States
First People's Hospital of Hangzhou

Recruiting

Endoscopic Scissors Cutting Nasobiliary Duct VS Bilateral Plastic Stent

Bile Duct Diseases | Hilar Cholangiocarcinoma | Klatskin Tumor | Biliary Disease | Biliary Stricture | Bile Duct Stenosis | Cholangiocarcinoma, Hilar

China
Hepatopancreatobiliary Surgery Institute of Gansu...

Not yet recruiting

Effect of 37℃ Non-ionic Contrast Agent During ERCP Procedure in Hilar Cholangiocarcinoma

Cholangitis

China
Erasmus Medical Center

Recruiting

Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma (POELH-II)

Adenocarcinoma | Cholangiocarcinoma | Intrahepatic Cholangiocarcinoma | Hilar Cholangiocarcinoma | Common Bile Duct Neoplasms

Netherlands, Belgium
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Chemotherapy Combined With Adebrelimab and Apatinib as the Perioperative Treatment in Patients With Biliary Tract Cancer

Resectable Intrahepatic Cholangiocarcinoma With High Risk of Recurrence

China
Massachusetts General Hospital
Exelixis

Completed

Cabozantinib (XL-184) Monotherapy for Advanced Cholangiocarcinoma

Bile Duct Cancer | Intrahepatic Cholangiocarcinoma | Cholangiocarcinoma of the Extrahepatic Bile Duct

United States
Zhejiang University

Recruiting

A Study to Evaluate the Safety and Efficacy of PRRT With 177Lu-EB-FAPI in Patients With Advanced Cholopancreatic Tumors (CISPD-5)

Advanced Pancreatic Cancer and Cholangiocarcinoma

China
McMaster University
Canadian Institutes of Health Research (CIHR); Khon Kaen University; Global Alliance...

Not yet recruiting

Evaluating a Community-Based Behaviour Change Communication Model to Prevent Cholangiocarcinoma in Khon Kaen, Thailand (eCHEC)

Cholangiocarcinoma | Liver Fluke-Related Cholangiocarcinoma | Opisthorchiasis

Thailand
Shanghai Zhongshan Hospital
RenJi Hospital; Xinhua Hospital, Shanghai Jiao Tong University School of Medicine and other collaborators

Recruiting

Phase II-III Clinical Trial of PD1 Antibody (Toripalimab), Lenvatinib and GEMOX Neoadjuvant Treatment for Resectable Intrahepatic Cholangiocarcinoma With High-risk Recurrence Factors

Intrahepatic Cholangiocarcinoma | Lenvatinib | PD1 Antibody | Gemox Chemotherapy

China
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bristol-Myers Squibb; National Cancer Institute (NCI); Syndax Pharmaceuticals

Completed

A Clinical Trial of Entinostat in Combination With Nivolumab for Patients With Previously Treated Unresectable or Metastatic Cholangiocarcinoma and Pancreatic Adenocarcinoma

Pancreatic Cancer | Cholangiocarcinoma | Metastatic Pancreatic Cancer | Unresectable Pancreatic Cancer | Metastatic Cholangiocarcinoma | Unresectable Cholangiocarcinoma

United States
Washington University School of Medicine

Completed

Stereotactic Body Radiotherapy for Hepatocellular Carcinoma, and Intrahepatic Cholangiocarcinoma

Carcinoma, Hepatocellular | Intrahepatic Cholangiocarcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Gemcitabine Hydrochloride, Cisplatin, and Nab-Paclitaxel in Treating Patients With Advanced or Metastatic Biliary Cancers

Unresectable Extrahepatic Bile Duct Carcinoma | Unresectable Gallbladder Carcinoma | Stage IIIA Gallbladder Cancer AJCC v7 | Stage IIIB Gallbladder Cancer AJCC v7 | Stage IVA Gallbladder Cancer AJCC v7 | Stage IVB Gallbladder Cancer AJCC v7 | Stage III Intrahepatic Cholangiocarcinoma AJCC v7 | Stage... and other conditions

United States
Zhou Fuxiang

Not yet recruiting

Umbilical Cord Blood Derived MAK Immune Cells Combined With Standard Second-Line Treatments for Hepatobiliary and Pancreatic Malignancies

Stage IV Pancreatic Cancer | Hepatocellular Carcinoma , Cholangiocarcinoma

China
Weill Medical College of Cornell University

Unknown

Photodynamic Therapy (PDT) Cholangiocarcinoma Registry (PDTRegistry)

Biliary Stricture | Unresectable Cholangiocarcinoma | Biliary Obstruction | Stent Obstruction

United States
Fudan University

Recruiting

Lenvatinib Plus Sintilimab in Patients With Immune Checkpoint Inhibitor Previously Treated Advanced Liver Cancer

Intrahepatic Cholangiocarcinoma

China
West China Hospital

Recruiting

A Machine-learning Model to Predict Lymph Node Metastasis of Intrahepatic Cholangiocarcinoma

Intrahepatic Cholangiocarcinoma | Machine Learning

China
Azienda Ospedaliera di Padova

Unknown

Liver Transplantation for Hilar Cholangiocarcinoma in Association With Neoadjuvant Radio- and Chemo-therapy

Primary Sclerosing Cholangitis | Hilar Cholangiocarcinoma

Italy
Institut für Klinische Krebsforschung IKF GmbH...
AstraZeneca

Recruiting

Immunotherapy Combined With Y-90 SIRT Therapy in Advanced Stage Intrahepatic Biliary Tract Cancer (BTC)

Intrahepatic Cholangiocarcinoma

Germany
National Cancer Institute (NCI)

Completed

Mesothelin-Targeted Immunotoxin LMB-100 in Combination With Tofacitinib in Persons With Previously Treated Pancreatic Adenocarcinoma, Cholangiocarcinoma and Other Mesothelin Expressing Solid Tumors

Epithelioid Mesothelioma | Cholangiocarcinoma, Extrahepatic | Neoplasms With Mesothelin Expression | Adenocarcinoma, Pancreatic

United States
Virogin Biotech Canada Ltd

Recruiting

An Open-Label, Multiple-Center, Phase IIa/IIb Clinical Trial to Evaluate the Efficacy, Safety and Tolerability of VG161 as Monotherapy and in Combination With Nivolumab for Treatment of Patients With Hepatocellular Carcinoma or Intrahepatic Cholangiocarcinoma

Hepatocellular Carcinoma | Intrahepatic Cholangiocarcinoma

United States
TriSalus Life Sciences, Inc.

Active, not recruiting

Pressure Enabled Delivery of SD-101 With Checkpoint Blockade for Primary Liver Tumors

Hepatocellular Carcinoma | Intrahepatic Cholangiocarcinoma

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

MRI-based Clinico-radiomics Predicting Lymph Node Metastasis Status of Hilar Cholangiocarcinoma

Hilar Cholangiocarcinoma

China
Institut für Klinische Krebsforschung IKF GmbH...

Active, not recruiting

Immunotherapy With Durva and Treme With or Without Capecitabine in Adjuvant Treatment for Biliary Tract Cancer

Intrahepatic Cholangiocarcinoma | Hilar Cholangiocarcinoma | Distal Cholangiocarcinoma | Gall Bladder Carcinoma | Biliary Tract Cancer (CCA)

Germany
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

Gemcitabine Hydrochloride and Cisplatin With or Without Nab-Paclitaxel in Treating Patients With Newly Diagnosed Advanced Biliary Tract Cancers

Stage III Intrahepatic Cholangiocarcinoma AJCC v8 | Stage IIIA Intrahepatic Cholangiocarcinoma AJCC v8 | Stage IIIB Intrahepatic Cholangiocarcinoma AJCC v8 | Stage III Gallbladder Cancer AJCC v8 | Stage IIIA Gallbladder Cancer AJCC v8 | Stage IIIB Gallbladder Cancer AJCC v8 | Unresectable Extrahepatic... and other conditions

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
First Affiliated Hospital of Jinan University; Shenzhen University General...

Recruiting

Pemigatinib Combined With PD-1 Inhibitor in Unresectable or Metastatic Intrahepatic Cholangiocarcinoma

Carcinoma | Digestive System Neoplasms | Intrahepatic Cholangiocarcinoma | First-line Treatment | PD-1 Inhibitor

China
University Hospital, Ghent

Completed

Feasibility of Radiotherapy and Concomitant Gemcitabine and Oxaliplatin in Locally Advanced Pancreatic Cancer and Distal Cholangiocarcinoma

Locally Advanced and Unresectable, But Non-metastatic Pancreatic Adenocarcinoma or Cholangiocarcinoma

Belgium
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Ramucirumab in Treating Patients With Advanced or Metastatic, Previously Treated Biliary Cancers That Cannot Be Removed by Surgery

Cholangiocarcinoma | Liver and Intrahepatic Bile Duct Carcinoma | Unresectable Gallbladder Carcinoma | Stage III Gallbladder Cancer AJCC v7 | Stage IIIA Gallbladder Cancer AJCC v7 | Stage IIIB Gallbladder Cancer AJCC v7 | Stage IV Gallbladder Cancer AJCC v7 | Stage IVA Gallbladder Cancer AJCC v7 | Stage... and other conditions

United States
Relay Therapeutics, Inc.

Active, not recruiting

REFOCUS: A First-in-Human Study of Highly Selective FGFR2 Inhibitor, RLY-4008, in Patients With ICC and Other Advanced Solid Tumors

Cholangiocarcinoma | Intrahepatic Cholangiocarcinoma | FGFR2 Gene Mutation | FGFR2 Amplification | FGFR2 Gene Fusion/Rearrangement | FGFR2 Gene Translocation | FGFR2 Gene Activation | Other Solid Tumors, Adult

United States, France, Italy, United Kingdom, Korea, Republic of, Spain, Taiwan, Sweden, Germany, Netherlands, Singapore, Australia, Hong Kong
Genoscience Pharma

Terminated

Study of GNS561 in Patients With Liver Cancer

Hepatocellular Carcinoma | Cholangiocarcinoma, Intrahepatic

France, United States, Belgium
Medivir

Active, not recruiting

A Study to Evaluate MIV-818 in Patients With Liver Cancer Manifestations

Hepatocellular Carcinoma | Intrahepatic Cholangiocarcinoma | Liver Metastases

Korea, Republic of, Spain, Belgium, United Kingdom
University of Zurich

Withdrawn

Response of Hepatic Tumors to Radioembolization (RESRAD)

Hepatocellular Carcinoma | Intrahepatic Cholangiocarcinoma | Liver Metastasis

Switzerland
West China Hospital

Not yet recruiting

Cadonilimab Combined With Liposomal Irinotecan Plus Leucovorin and Fluorouracil for Advanced Cholangiocarcinoma

Cholangiocarcinoma

Clinical Trials on Cholangiocarcinoma, Perihilar

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