Clinical Trials on Chromosomal Abnormalities

Total 26831 results

AC Immune SA

Withdrawn

A Study of ACI-24 in Adults With Down Syndrome

Down Syndrome
University of Arkansas
Down Syndrome Research Foundation; Arkansas Children Research Institute

Withdrawn

Physiological Abnormalities Associated With Down Syndrome

Down Syndrome
Riphah International University

Completed

Effect of Neuro Developmental Therapy in Infants With Down Syndrome

Down Syndrome

Pakistan
University of Wisconsin, Madison

Completed

Feasibility and Dose Tolerability of HD-tDCS in Healthy Adults and Children With Down Syndrome

Down Syndrome

United States
National Human Genome Research Institute (NHGRI)

Completed

The Experience of Caregivers of Children With Down Syndrome

Down Syndrome

United States
University of Illinois at Chicago
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Terminated

Blood Flow in Individuals With Down Syndrome

Down Syndrome

United States
Eisai Co., Ltd.

Completed

A Double-blind, Placebo-controlled Comparative Study and Open-label Extension Study to Confirm the Efficacy and Safety of E2020 in Subjects With Down Syndrome Having Regression Symptoms and Disabled Activities of Daily Living.

Down Syndrome

Japan
University of Sao Paulo

Completed

Performance Analysis in Down Syndrome on Mobile Phone

Down Syndrome

Brazil
University of Arkansas

Completed

Assessment of Bone Density and Bone Turnover Markers in Patients With Down Syndrome and Comparison to the Ts65Dn Model

Down Syndrome

United States
Chugai Pharmaceutical

Completed

Non-drug Study to Assess the Suitability of Assessment Scales in Japanese Individuals With Down Syndrome Aged 6-30

Down Syndrome

Japan
Hoffmann-La Roche

Completed

A Non-Drug Study of The Suitability of Neurocognitive Tests And Functioning Scales For The Measurement of Cognitive And Functioning Changes in Individuals With Down Syndrome

Down Syndrome

United States, France, Italy, Canada, United Kingdom, Argentina, Spain
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Symbolic Representation in Young Children With Down Syndrome

Down Syndrome

Brazil
Institut Jerome Lejeune
Fondation Jérôme Lejeune

Completed

Efficacy Study of Folinic Acid to Improve Mental Development of Children With Down Syndrome

Down Syndrome

France
University of North Carolina, Chapel Hill
National Human Genome Research Institute (NHGRI); East Carolina University; Mission...

Active, not recruiting

North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2 (NCGENES2)

Neuromuscular Diseases | Movement Disorders | Intellectual Disability | Autism Spectrum Disorder | Microcephaly | Hearing Loss | Genetic Disease | Inborn Errors of Metabolism | Epilepsy; Seizure | Brain Malformation | Hypotonia | Development Delay | Chromosome Abnormality | Dysmorphic Features | Skeletal Dysplasia | Congenital... and other conditions

United States
University of Colorado, Denver

Completed

Micro RNAs as a Marker of Aortic Aneurysm in Hereditary Aortopathy Syndromes

Marfan Syndrome | Turner Syndrome | Loeys-Dietz Syndrome | Thoracic Aortic Aneurysm and Dissection Syndromes | Ehlers-Danlos Type IV Syndrome

United States
University College, London

Unknown

Pubertal Induction in Individuals With Hypogonadism

Hypopituitarism | Primary Ovarian Insufficiency | Turner's Syndrome | Hypogonadotrophic Hypogonadism | Primary Amenorrhoea | Hypothalamic Amenorrhoea

United Kingdom
University of Aarhus

Unknown

Prospective Characterization of the Heart, Aorta and Blood Pressure in Turner Syndrome. Association With Aortic Dissection. (TSCORII)

Hypertension | Ischemic Heart Disease | Aortic Aneurysm | Turner Syndrome | Congenital Heart Defect

Denmark
Novo Nordisk A/S

Completed

Safety and Efficacy of Long-term Somatropin Treatment in Children (GrowthWIN II)

Turner Syndrome | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Genetic Disorder | Foetal Growth Problem | Small for Gestational Age | Growth Disorder | Idiopathic Short Stature

Germany
LG Chem

Recruiting

Long-term Safety and Effectiveness of Growth Hormone With GHD, TS, CRF, SGA , ISS and PWS in Children (LGS)

Growth Hormone Deficiency | Chronic Renal Failure | Turner Syndrome | Small for Gestational Age | Idiopathic Short Stature

Korea, Republic of
Radboud University Medical Center
Princess Beatrix Muscle Foundation

Completed

Neuralgic Amyotrophy: Central Reorganization and Rehabilitation After Peripheral Dysfunction (NA-CONTROL)

Parsonage Turner Syndrome | Neuralgic Amyotrophy | Neuralgic Amyotrophy, Hereditary | Brachial Neuritis

Netherlands
Merck KGaA, Darmstadt, Germany

Completed

Predictive Markers in Growth Hormone Deficiency (GHD) and Turner Syndrome (TS) Children Treated With SAIZEN®

Growth Hormone Deficiency | Turner Syndrome

Argentina, Australia, Austria, Canada, France, Germany, Italy, Norway, Russian Federation, Singapore, Spain, Sweden, United Kingdom
Laboratoires Vivacy

Recruiting

Study of a Novel Hyaluronic Acid Based Gel for Volume Deficiency in the Mid-face (FaceHyal) (FaceHyal)

Aging | Aesthetics | Volume Deficiency in the Mid-Face

France
Perha Pharmaceuticals
Göteborg University; Proteas Bioanalytics

Recruiting

Phosphoproteomic Profile of Children With Down Syndrome (PEPS)

Down Syndrome

France
University of Colorado, Denver
National Institute on Aging (NIA)

Recruiting

Trial to Evaluate Safety and Efficacy of GM-CSF /Sargramostim in Down Syndrome

Down Syndrome

United States
Massachusetts Institute of Technology

Recruiting

Gamma Frequency Stimulation in Individuals With Down Syndrome

Down Syndrome

United States
Aelis Farma
European Commission

Active, not recruiting

Phase 1/2 Trial of AEF0217 in Participants With Down Syndrome (MDDS)

Down Syndrome

Spain
University of Illinois at Chicago
American College of Sports Medicine

Completed

Blood Flow and Blood Pressure Investigation in Down Syndrome (FBI21)

Down Syndrome

United States
Taibah University

Completed

Motorized Movement Therapy & Pulmonary Functions in Down Syndrome

Down Syndrome | Pulmonary Functions

Saudi Arabia
Boston Children's Hospital
Baylor College of Medicine; Vanderbilt University Medical Center; Children's... and other collaborators

Completed

Characterization of Angelman Syndrome

Angelman Syndrome

United States
University of Mississippi Medical Center

Completed

Balance Bike Training in Down Syndrome

Down Syndrome | Postural Balance

United States
Gazi University

Completed

The Effects of Kinesiotaping on Balance in Children With Down Syndrome.

Down Syndrome | Balance

Turkey
University of Colorado, Denver
Forest Laboratories

Completed

Efficacy and Safety of Memantine Hydrochloride in Enhancing the Cognitive Abilities of Young Adults With Down Syndrome

Down Syndrome

United States
Institut Jerome Lejeune
Fondation Jérôme Lejeune

Completed

Correlations Phenotype / Genotype in Down Syndrome (INTREPID)

Down Syndrome

France
Changhai Hospital

Not yet recruiting

Analyzing the Urine During BCG Instillation in Bladder Cancer Patients for Disease Followup

Bladder Cancer

China
Riphah International University

Completed

Treadmill Training With and Without Weighted Ankle Cuffs on Gait Parameters

Down's Syndrome

Pakistan
Cairo University

Completed

Effect of the Sensory Integration Approach on Balance and Motor Coordination in Children With Down Syndrome

Down Syndrome

Egypt
Badr University

Completed

Effect of Arm Ergometry on Children With Down Syndrome

EFFECT OF ARM ERGOMETRY ON RESPIRATION

Egypt
University of Colorado, Denver

Completed

Nutritional Formulation for Angelman Syndrome (FANS)

Angelman Syndrome

United States
University of Aarhus

Recruiting

The Danish TURNER Cryopreservation Study (DANTE)

Fertility Disorders | Turner Syndrome | Premature Ovarian Failure

Denmark
LG Life Sciences

Completed

Evaluation of the Ease of Use, Preference, and Safety of EutropinPen Inj.

Growth Hormone Deficiency | Chronic Renal Failure | Turner Syndrome | Infant, Small for Gestational Age | Short Stature, Idiopathic

Korea, Republic of
Institut Jerome Lejeune
Fondation Jérôme Lejeune

Completed

Pilot Study of Auto-immune Abnormalities Associated With Down Syndrome (IMMUTRI)

Down Syndrome With and Without Auto Immune Abnormalities

France
Riphah International University

Not yet recruiting

Effect of Group-Task-Oriented Training on GMFM and ADL in Children With DS

Downs Syndrome

Pakistan
University of Kansas Medical Center
HRSA/Maternal and Child Health Bureau

Not yet recruiting

GameSquad for Adults With Down Syndrome

Down Syndrome | Physical Inactivity
Cairo University

Not yet recruiting

Change in Quality of Life After Full Mouth Rehabilitation Under General Anesthesia in a Group of Egyptian Children With Down Syndrome

Pediatric Dentistry
Massachusetts General Hospital
National Institutes of Health (NIH)

Recruiting

Developing a Down Syndrome Health Instrument

Health, Subjective | Down Syndrome

United States
Children's Hospital Medical Center, Cincinnati
University of California, Davis

Recruiting

Evaluating Treatment of ADHD in Children With Down Syndrome (TEAM-DS)

ADHD | Down Syndrome

United States
Odense University Hospital

Completed

Use of eHealth in Communication With Patients About Prenatal Diagnosis (HIIP)

Health Knowledge, Attitudes, Practice | Downs Syndrome

Denmark
Stanford University

Completed

Effects of Social Gaze Training on Brain and Behavior in Fragile X Syndrome

Intellectual Disability | Fragile X Syndrome

United States
Marinus Pharmaceuticals
University of California, Davis; U.S. Army Medical Research and Development...

Completed

Ganaxolone Treatment in Children With Fragile X Syndrome

Fragile x Syndrome

Belgium, United States
RTI International
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Decisional Capacity and Informed Consent in Fragile X Syndrome

Fragile X Syndrome (FXS)

United States

Clinical Trials on Chromosomal Abnormalities

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Cote d'Ivoire

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations