Clinical Trials on Chromosome Abnormality in New Zealand

Total 168 results

Bristol-Myers Squibb

Completed

A Phase III Study of Dasatinib vs Imatinib in Patients With Newly Diagnosed Chronic Phase Chronic Myeloid Leukemia (DASISION)

Myeloid Leukemia, Chronic

Germany, India, Japan, Korea, Republic of, Turkey, Chile, China, Spain, Australia, France, Poland, Mexico, Colombia, Belgium, Austria, Italy, Peru, Greece, Brazil, Czech Republic, Hungary, Russian Federation, Netherlands, Argentina, Den... and more
Garvan Institute of Medical Research

Completed

Gut Derived Hormones, Body Composition and Metabolism in Prader-Willi Syndrome

Prader-Willi Syndrome

Australia
Seaside Therapeutics, Inc.

Completed

Efficacy and Safety Study of STX209 (Arbaclofen) for the Treatment of Social Withdrawal in Children With Fragile X Syndrome (Harbor-C)

Fragile X Syndrome

United States
Bristol-Myers Squibb

Completed

Long-term Safety of Dasatinib in Patients With Chronic Myelogenous Leukemia or Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (START rollover)

Leukemia

Germany, Italy, Korea, Republic of, Sweden, Thailand, United States, Australia, France, Poland, Switzerland, Spain, Ireland, Peru, Brazil, South Africa, Canada, Argentina, Hungary, Finland, Israel, Norway, Russian Federation, United... and more
Novartis Pharmaceuticals

Recruiting

Study to Determine the Dose and Safety of Asciminib in Pediatric Patients With Chronic Myeloid Leukemia

Myeloid Leukemia, Philadelphia Positive

Korea, Republic of, Germany, France, United States, Greece, Hungary, Italy, Japan, Poland, Russian Federation, Thailand, Turkey, China, Netherlands
Montefiore Medical Center
Jazz Pharmaceuticals; Foundation for Prader-Willi Research

Active, not recruiting

CBDV vs Placebo in Children and Adults up to Age 30 With Prader-Willi Syndrome (PWS)

Prader-Willi Syndrome

United States
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical...

Unknown

Autonomic Regulation in Prader-Willi Syndrome

Autonomic Dysfunction

Taiwan
Hoffmann-La Roche

Completed

A Study of RO4917523 in Patients With Fragile X Syndrome

Fragile X Syndrome

France, Spain, United States, Peru, Canada, United Kingdom, Chile, Argentina, Mexico, Sweden
Institute for Neurodegenerative Disorders

Completed

A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions (FPEB)

Parkinson Disease | Alzheimer Disease | Mild Cognitive Impairment | Fragile X Syndrome | Huntington Disease | Autistic Spectrum Disorders

United States
Novartis Pharmaceuticals

Completed

An Extension Study to Determine the Safety and Anti-Leukemic Effects of Imatinib Mesylate in Adult Participants With Ph+ Leukemia

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Philadelphia Positive Chronic Myeloid Leukemia

United States, Germany, United Kingdom, France, Italy
Icahn School of Medicine at Mount Sinai
National Cancer Institute (NCI); Myeloproliferative Disorders-Research Consortium

Completed

Correlative Biomarker Study in Patients With Myeloproliferative Disorders

Polycythemia Vera | Essential Thrombocythemia | Myelofibrosis | Idiopathic Myelofibrosis | Myeloproliferative Disease

United States, Canada, Italy, United Kingdom
Weill Medical College of Cornell University
National Institutes of Health (NIH); PWSAUSA

Terminated

Effect of Rimonabant on Weight Gain and Body Composition in Adults With Prader Willi Syndrome (PWS)

Prader-willi Syndrome

United States
NYU Langone Health
Winthrop University Hospital

Withdrawn

Dose Clinical Trial of Guanfacine Extended Release for the Reduction of Aggression and Self-injuries Behavior Associated With Prader-Willi Syndrome

Prader-Willi Syndrome

United States
Montefiore Medical Center

Recruiting

Intranasal Oxytocin vs. Placebo for the Treatment of Hyperphagia in Prader-Willi Syndrome

Hyperphagia | Prader-Willi Syndrome

United States
Montefiore Medical Center
Foundation for Prader-Willi Research

Completed

Oxytocin vs. Placebo for the Treatment Hyperphagia in Children and Adolescents With Prader-Willi Syndrome (OXT-PWS)

Hyperphagia | Prader-Willi Syndrome

United States
National Cancer Institute (NCI)

Active, not recruiting

Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | B Acute Lymphoblastic Leukemia | Recurrent Acute Lymphoblastic Leukemia | Refractory Acute Lymphoblastic Leukemia | B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1

United States
Bionano Genomics
Columbia University; University of Iowa; Medical College of Wisconsin; Augusta... and other collaborators

Recruiting

Validation of Optical Genome Mapping for the Identification of Constitutional Genomic Variants in a Postnatal Cohort

Intellectual Disability | Autism Spectrum Disorder | Fragile X Syndrome | Developmental Disability | Congenital Anomaly | Facioscapulohumeral Muscular Dystrophy 1

United States
Life Molecular Imaging SA

Completed

Phase II Study of Florbetaben (BAY94-9172) PET Imaging for Detection/Exclusion of Cerebral β-amyloid.

Down Syndrome | Amyloid Beta-protein

United States
Sequenom, Inc.
PRA Health Sciences

Completed

Noninvasive Screening for Fetal Aneuploidy: A New Maternal Plasma Marker

Pregnancy | Down Syndrome | Aneuploidy | Edwards Syndrome

United States, France
Foundation for Prader-Willi Research
RTI International

Recruiting

A Clinical Evaluation of Non-Invasive Vagus Nerve Stimulation for Temper Outbursts in People With PWS (VNS4PWS)

Prader-Willi Syndrome

United States
Novo Nordisk A/S

Recruiting

A Research Study to Compare Somapacitan Once a Week With Norditropin® Once a Day in Children Who Need Help to Grow (REAL 8)

SGA, Turner Syndrome, Noonan Syndrome, ISS

Belgium, Korea, Republic of, United States, Ireland, Malaysia, United Kingdom, Finland, France, Netherlands, Thailand, China, Japan, Portugal, Israel, Brazil, India, Austria, Bulgaria, Canada, Croatia, Germany, Greece, Italy, Poland, Saudi... and more
University of Central Florida
National Institute on Deafness and Other Communication Disorders (NIDCD); University...

Completed

Building Sentences With Preschoolers Who Use AAC

Down Syndrome | Speech Sound Disorder | Speech Disorders in Children | Speech Intelligibility | Speech and Language Disorder

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Donor Stem Cell Transplant in Treating Young Patients With Acute Myeloid Leukemia With Monosomy 7, -5/5q-, High FLT3-ITD AR, or Refractory or Relapsed Acute Myelogenous Leukemia

Leukemia

United States, Canada
Ferring Pharmaceuticals

Completed

Treatment of Hyperphagia Behavioral Symptoms in Children and Adults Diagnosed With Prader-Willi Syndrome

Hyperphagia in Prader-Willi Syndrome

United States
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical...

Completed

Prader-Willi Syndrome Body Composition

Body Weight Changes | Sarcopenia | Prader Labhart Willi Syndrome

Taiwan
Hoffmann-La Roche

Active, not recruiting

A Study To Investigate The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of RO7248824 In Participants With Angelman Syndrome

Angelman Syndrome

United States, Spain, Netherlands, Italy
Rhythm Pharmaceuticals, Inc.

Completed

Phase 2 Trial to Evaluate Safety and Efficacy of Setmelanotide (RM-493) in Obese Participants With Prader-Willi Syndrome

Prader-Willi Syndrome

United States
Bristol-Myers Squibb

Completed

Dasatinib (BMS-354825) in Subjects With Lymphoid Blast Phase Chronic Myeloid Leukemia or Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Chronic Myeloid Leukemia | Leukemia, Lymphoblastic, Acute, Philadelphia-positive

Netherlands, United States, Italy, Argentina, Austria, Brazil, Canada, Germany, Peru, United Kingdom, France, Korea, Republic of, Sweden, Finland, Australia, Israel, Belgium, Denmark, Norway, Switzerland
NYU Langone Health

Enrolling by invitation

Self-Face Recognition After Face Transplantation

Disfigurement of Face

United States
Maimonides Medical Center
Foundation for Prader-Willi Research

Recruiting

Impact of Bright Light Therapy on Prader-Willi Syndrome (PWS-LT)

Body Weight | Hyperphagia | Prader-Willi Syndrome | Mood | Behavior | Excessive Daytime Sleepiness

United States
Maimonides Medical Center

Recruiting

Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome (PWS-GXR)

Aggression | Behavioral Symptoms | Pathologic Processes | Nervous System Diseases | Obesity | Neurologic Manifestations | Neurobehavioral Manifestations | Congenital Abnormalities | Overnutrition | Nutrition Disorders | Genetic Diseases, Inborn | Intellectual Disability | Self-Injurious Behavior | Abnormalities, Multiple and other conditions

United States
Albert Einstein College of Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Examining Genetic Factors That Affect the Severity of 22q11.2 Deletion Syndrome

DiGeorge Syndrome | 22q11.2 Deletion Syndrome

United States
State University of New York - Upstate Medical...
Albert Einstein College of Medicine

Completed

Genetic Modifiers for 22q11.2 Syndrome (VCFS)

22q11.2 Deletion Syndrome

United States
State University of New York - Upstate Medical...
National Institute of Mental Health (NIMH)

Completed

Computerized Cognitive Skills Training for Adolescents With Velocardiofacial Syndrome

Velocardiofacial Syndrome

United States
National Cancer Institute (NCI)

Completed

Sorafenib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Leukemia

Juvenile Myelomonocytic Leukemia | Recurrent Disease | Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Myeloid Leukemia | Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Childhood Solid Neoplasm | Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Philadelphia... and other conditions

United States, Canada
Hoffmann-La Roche

Recruiting

Study to Investigate the Pharmacokinetics and Safety and to Provide Proof of Mechanism of Alogabat in Children and Adolescents Aged 5-17 Years With Angelman Syndrome (AS) With Deletion Genotype. (Aldebaran)

Angelman Syndrome

Australia, United States, Spain, Italy, France, Germany
Radius Pharmaceuticals, Inc.

Terminated

A Study to Assess RAD011 (Cannabidiol Oral Solution) for the Treatment of Participants With Prader-Willi Syndrome (SCOUT-015)

Prader-Willi Syndrome

United States
Ultragenyx Pharmaceutical Inc

Not yet recruiting

Long-term Extension of GTX-102 in Angelman Syndrome

Angelman Syndrome

United States, Australia, Canada, Germany, United Kingdom, Israel, France, Spain
Soleno Therapeutics, Inc.

Active, not recruiting

Open-Label Extension Study of DCCR in Patients With Prader-Willi Syndrome

Prader-Willi Syndrome

United States, United Kingdom
New York State Institute for Basic Research
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Unknown

Vitamin E in Aging Persons With Down Syndrome

Alzheimer Disease | Down Syndrome

United States, Canada, Australia, United Kingdom
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Idasanutlin, Ixazomib Citrate, and Dexamethasone in Treating Patients With Relapsed Multiple Myeloma

Recurrent Plasma Cell Myeloma | Loss of Chromosome 17p

United States
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC)

Marfan Syndrome | Turner Syndrome | Ehlers-Danlos Syndrome | Loeys-Dietz Syndrome | Shprintzen-Goldberg Syndrome | FBN1, TGFBR1, TGFBR2, ACTA2 or MYH11 Genetic Mutation | Bicuspid Aortic Valve Without Known Family History | Bicuspid Aortic Valve With Family History | Bicuspid Aortic Valve With Coarctation and other conditions

United States
Bausch Health Americas, Inc.

Terminated

Metyrosine (Demser®) for the Treatment of Psychotic Disorders in Patients With Velocardiofacial Syndrome

Psychosis | Velo-cardio-facial Syndrome

United States
Ultragenyx Pharmaceutical Inc

Active, not recruiting

A Study of the Safety and Tolerability of GTX-102 in Children With Angelman Syndrome

Angelman Syndrome

United States, United Kingdom, Canada, Australia, France, Germany, Spain, Israel
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Study of Blood Samples From Newborns With Down Syndrome

Myeloid Proliferations Associated With Down Syndrome

United States, Canada, Australia, Puerto Rico
Soleno Therapeutics, Inc.

Completed

Open-Label Extension Study of DCCR in PWS Followed by Double-Blind, Placebo-Controlled, Randomized Withdrawal Period

Prader-Willi Syndrome

United States, United Kingdom
Soleno Therapeutics, Inc.

Completed

A Study of Diazoxide Choline in Patients With Prader-Willi Syndrome

Prader-Willi Syndrome

United States, United Kingdom
Gedeon Richter Plc.

Recruiting

Study to Evaluate Efficacy, Safety, and Tolerability of RGH-706 in Prader-Willi Syndrome

Prader-Willi Syndrome

United States, Spain, Czechia, Italy, France
Zafgen, Inc.

Terminated

Double-Blind, Placebo Controlled, Phase 3 Trial of ZGN-440 (Beloranib) in Obese Subjects With Prader-Willi Syndrome (bestPWS)

Obesity | Prader-Willi Syndrome

United States
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome

Acute Myeloid Leukemia | Down Syndrome | Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Myeloid Leukemia Associated With Down Syndrome

United States, Canada, Saudi Arabia, Puerto Rico, Australia, New Zealand

Clinical Trials on Chromosome Abnormality in New Zealand

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