Clinical Trials on Chromosome 15q Duplication

Total 1341 results

Pfizer

Completed

Bioequivalence And Food Effect Study Of Bosutinib In Healthy Subjects

Philadelphia Chromosome Positive (Ph+) Chronic Myeloid Leukemia (CML)

Singapore
IVI Barcelona

Completed

Aneuploidy Rates of in Vitro Matured Oocytes (IVM)

Aneuploidy

Spain
Stanford University

Recruiting

Pregnancy and Developmental Outcomes After Transfer of Reportedly Aneuploid or Mosaic Embryos (TAME)

Aneuploidy | Mosaicism

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Multicenter Trial Treatment of Philadelphia Chromosome Negative B-cell Acute Lymphoblastic Leukemia of Young Adults (GRAALL-2014/B)

Philadelphia Chromosome Negative Adult B-cell Acute Lymphoblastic Leukemia

France
Boston Children's Hospital
Phelan-McDermid Syndrome Foundation

Completed

Mapping the Phenotype in Adults With Phelan-McDermid Syndrome

Intellectual Disability | Autism Spectrum Disorder | Phelan-McDermid Syndrome

United States
Antonio Persico
University of Bari; Associazione Italiana Sindrome di Phelan-McDermid (AISPHEM)

Enrolling by invitation

Q10 Ubiquinol in Autism Spectrum Disorder and in Phelan-McDermid Syndrome. (Q10ASD)

Autism Spectrum Disorder | Phelan-McDermid Syndrome

Italy
Hospices Civils de Lyon

Completed

Fertility Preservation in Cases of Klinefelter Syndrome. (FERTIPRESERVE)

Klinefelter Syndrome

France
University of Pittsburgh

Terminated

Fertility Assessment in Patients With Klinefelter Syndrome

Klinefelter Syndrome

United States
Odense University Hospital
Aarhus University Hospital; University of Copenhagen

Completed

Subcapsular Orchiectomy in Men With Klinefelter Syndrome

Klinefelter Syndrome

Denmark
Brian Jonas
National Cancer Institute (NCI); Pharmacyclics LLC.

Recruiting

Ibrutinib and Blinatumomab in Treating Patients With Relapsed or Refractory B Acute Lymphoblastic Leukemia

Philadelphia Chromosome Positive | Adult B Acute Lymphoblastic Leukemia

United States
National Human Genome Research Institute (NHGRI)

Completed

Adaptation Among Adolescents and Adults With Klinefelter Syndrome

Klinefelter Syndrome

United States
University of Wisconsin, Madison
Solvay Pharmaceuticals

Withdrawn

Adaptive Behavior Assessment of Men With 49, XXXXY, Klinefelter Syndrome

Klinefelter Syndrome

United States
University of Aarhus
Aarhus University Hospital

Completed

Neuropsychologic, Neuroradiologic, Endocrinologic, and Genetic Aspects of Klinefelter Syndrome

Klinefelter Syndrome

Denmark
Boston Children's Hospital

Completed

Klinefelter Fertility Preservation

Klinefelter Syndrome

United States
Hospital Clínico Universitario de Valladolid

Completed

Genomic Instability in Vascular Surgeons (IRADIENT)

Radiation Exposure | Cytogenetic Abnormality

Spain
RIVAGES

Not yet recruiting

Usefulness of the Medissimo Nurse Application for Supporting Medication Compliance in Elderly People With Chronic Polypathologies

Chronic Disease | Medication Compliance | Polypathology | Elderly Person | Digital Application
Cindy Cisneros

Completed

Non-Invasive Chromosomal Evaluation of 22q11.2 (22Q)

22q.11.2 Deletion/Duplication

Belgium
Applied Spectral Imaging Ltd.

Completed

Detection of Chromosomal Aberrations in Non-small Cell Lung Cancer (NSCLC) Using Fluorescent in Situ Hybridization (FISH) (ALK Test)

Non-small Cell Lung Cancer (NSCLC)

United States
University of Aarhus
Lundbeck Foundation; AP Moeller Foundation; The Korning Foundation Denmark

Completed

X-chromosome Inactivation, Epigenetics and the Transcriptome

Aortic Aneurysm | Turner Syndrome | Klinefelter Syndrome | Triple X Syndrome | 47 XYY Syndrome

Denmark
University of Colorado, Denver
Children's Hospital Colorado

Recruiting

Generating Advancements Through Longitudinal Analysis in X and Y Variations (GALAXY) (GALAXY)

Sex Chromosome Aneuploidy

United States
University of Colorado, Denver
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

TESTO: Testosterone Effects on Short-Term Outcomes in Infants With XXY (TESTO)

Klinefelter Syndrome

United States
Renato Melaragno

Unknown

Phase II Study for Safety and Efficacy Evaluation of Imatinib Mesylate in Children With Chronic Myeloid Leukemia (CML) Philadelphia Chromosome-positive (Ph+)

Chronic Myeloid Leukemia (CML) With Philadelphia Chromosome-positive (Ph+)

Brazil
Bristol-Myers Squibb

Completed

A Study of Dasatinib in Chronic Phase Philadelphia Chromosome Positive Chronic Myeloid Leukemia

Myeloid Leukemia, Chronic

Japan
Eyup Hakan Duran

Recruiting

Preimplantation Genetic Testing for Aneuploidy Counseling (PGT-A)

Patient Education

United States
IVI Vigo
Instituto Valenciano de Infertilidad, IVI VALENCIA; Juno Therapeutics, Inc.

Not yet recruiting

Embryos With Preimplantation Genetic Testing for Aneuploidies (PGT-A) Inconclusive Result: Clinical Implications

Embryo Disorder
The University of Hong Kong

Recruiting

RCT of niPGT for Aneuploidy and Morphology Compared With Morphology Alone in IVF

Preimplantation Diagnosis

China
Instituto Valenciano de Infertilidad, IVI VALENCIA

Completed

Embryo Aneuploidies and Ovarian Stimulation

Embryo Aneuploidies

Spain
Instituto Valenciano de Infertilidad, IVI VALENCIA

Terminated

Embryo Aneuploidies and Morphokinetics in Ovarian Stimulated and Non Stimulated IVF Cycles (AMOS)

Euploid Embryos

Spain
Cindy Cisneros

Completed

Development of a Prenatal Test for Fetal Aneuploidy Detection

Fetal Complications

United States
Reproductive Endocrinology Associates of Charlotte

Completed

Aneuploidy Rates in Advanced Maternal Age Patients Supplemented With Coenzyme Q10 (CoQ10) Versus Those That Are Not: a Pilot Study

Aneuploidy | Mitochondrial DNA

United States
IVI Madrid

Terminated

Aneuploidy Rate and Stimulation Protocol: Recombinant Follicle Stimulating Hormone (FSH) Versus Human FSH

Aneuploidy Rate

Spain
Center for Reproductive an Genetic Health

Unknown

The Effectiveness of Blastocentesis Versus Trophectoderm Biopsy

Abnormal Karyotype

United Kingdom
National Eye Institute (NEI)

Completed

Dry Eye in Women With Turner Syndrome and Women With Premature Ovarian Failure

Menopause | Turner Syndrome | Ovarian Failure, Premature | Sex Chromosome Aberrations | Perimenopause

United States
Sakarya University

Recruiting

The Effect of Mobile Application on Hypothyroid Patients

Hypothyroidism | Symptoms and Signs | Mobile Application | Digital Health | Symptom Management

Turkey
Novartis Pharmaceuticals

Not yet recruiting

Clinical Study of Asciminib in Previously Treated Indian Patients With Ph+ CML-CP Without T315I Mutation and in Patients With Ph+ CML-CP With T315I Mutation (ASC4INDIA)

Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase
University of Washington
Incyte Corporation

Recruiting

Chemotherapy (DA-EPOCH+/-R) and Targeted Therapy (Tafasitamab) for the Treatment of Newly-Diagnosed Philadelphia Chromosome Negative B Acute Lymphoblastic Leukemia

B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative

United States
Gruppo Italiano Malattie EMatologiche dell'Adulto

Recruiting

Sequential Treatment With Ponatinib and Blinatumomab vs Chemotherapy and Imatinib in Newly Diagnosed Adult Ph+ ALL

ALL, Adult | Philadelphia-Positive ALL | Acute Lymphoblastic Leukemia (Philadelphia Chromosome Positive)

Italy
Boston Children's Hospital
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Mapping the Genotype, Phenotype, and Natural History of Phelan-McDermid Syndrome

Intellectual Disability | Autism Spectrum Disorder | Phelan-McDermid Syndrome

United States
Icahn School of Medicine at Mount Sinai
National Institute of Neurological Disorders and Stroke (NINDS)

Enrolling by invitation

A Controlled Trial of Growth Hormone in Phelan-McDermid Syndrome and Idiopathic Autism

Autism Spectrum Disorder (ASD) | Phelan-McDermid Syndrome

United States
Novartis Pharmaceuticals

Active, not recruiting

A Study of Oral Asciminib Versus Other TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP

Chronic Myeloid Leukemia (CML) Philadelphia Chromosome Positive

United States, China, Hungary, Japan, Belgium, Germany, Canada, Singapore, Australia, Israel, Netherlands, Spain, Italy, Korea, Republic of, Bulgaria, France, United Kingdom, Czechia, Sweden, India, Malaysia, Denmark, Taiwan, Norway, Fi... and more
Gruppo Italiano Malattie EMatologiche dell'Adulto

Active, not recruiting

Sequential Chemotherapy and Blinatumomab to Improve MRD Response and Survival in Acute Lymphoblastic Leukemia (LAL2317)

Acute Lymphoid Leukemia | Philadelphia Chromosome-Negative B-Cell Precursor

Italy
Thomas Jefferson University
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Androgen Effect on Klinefelter Syndrome Motor Outcome

Klinefelter Syndrome

United States
University of Colorado, Denver

Completed

Body Composition in Infants With Klinefelter Syndrome and Effects of Testosterone Treatment

Klinefelter Syndrome

United States
Novartis Pharmaceuticals

Recruiting

A Study to Investigate Tolerability and Efficacy of Asciminib (Oral) Versus Nilotinib (Oral) in Adult Participants (≥18 Years of Age) With Newly Diagnosed Philadelphia Chromosome Positive Chronic Myelogenous Leukemia in Chronic Phase (Ph+ CML-CP) (ASC4START)

Philadelphia Chromosome-Positive Chronic Myeloid Leukemia

Singapore, France, Germany, United Arab Emirates, Greece, Italy, Czechia, Hungary, United States, Oman, Malaysia, Korea, Republic of, Turkey, Bulgaria, Canada, Slovakia, United Kingdom, Argentina, Jordan, Romania, South Africa, Sw... and more
Crystal Mackall, MD
California Institute for Regenerative Medicine (CIRM)

Active, not recruiting

CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells With or Without NKTR-255 in Adults With Recurrent or Refractory B Cell Malignancies

B Acute Lymphoblastic Leukemia | Philadelphia Chromosome Positive | Minimal Residual Disease | CD19 Positive

United States
University of Colorado, Denver
National Institute of Neurological Disorders and Stroke (NINDS); Children's... and other collaborators

Completed

Study of Psychological and Motor Effects of Testosterone in Adolescents With XXY/Klinefelter Syndrome (TestoXXY/KS)

Klinefelter Syndrome | XXY Syndrome

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Pembrolizumab and Blinatumomab in Treating Participants With Recurrent or Refractory Acute Lymphoblastic Leukemia

Philadelphia Chromosome Positive | Recurrent Acute Lymphoblastic Leukemia | Refractory Acute Lymphoblastic Leukemia | CD19 Positive

United States
Centre Leon Berard

Active, not recruiting

Safety and Efficacy of Ponatinib Followed by Imatinib in Patients With Chronic Myelogenous Leukemia in Chronic Phase (TIPI)

Philadelphia Chromosome Positive CML | BCR-ABL Positive Chronic Myelogenous Leukemia

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

ABL001 for the Treatment of Chronic Myeloid Leukemia in Patients Who Are on Therapy With Tyrosine Kinase Inhibitor

Philadelphia Chromosome Negative, BCR-ABL1 Positive Chronic Myelogenous Leukemia

United States
Versailles Hospital

Active, not recruiting

Study of Inotuzumab Ozogamicin Combined to Chemotherapy in Older Patients With Philadelphia Chromosome-negative CD22+ B-cell Precursor ALL (EWALL-INO)

Acute Lymphoblastic Leukemia (ALL) - Philadelphia Chromosome (Ph)-Negative CD22+ B-cell Precursor (BCP)

France

Clinical Trials on Chromosome 15q Duplication

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