Clinical Trials on Chronic Graft-versus-host Disease

Total 58822 results

University of California, San Francisco

Recruiting

UCSF PANC Cyst Registry (UCSF PCR)

Pancreatic Neoplasms | Pancreatic Cancer | Pancreatic Diseases | Pancreatic Ductal Adenocarcinoma | Pancreatic Cyst | Intraductal Papillary Mucinous Neoplasm | Mucinous Cyst | Pancreatic Intraductal Papillary Mucinous Neoplasm

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Study of Symptoms Caused by Cancer and Cancer Therapy in Patients With Invasive Breast, Lung, Prostate, or Colorectal Cancer

Pain | Breast Cancer | Colorectal Cancer | Lung Cancer | Prostate Cancer | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment

United States
Spark Therapeutics

Completed

Dose-finding Study of SPK-8016 Gene Therapy in Patients With Hemophilia A to Support Evaluation in Individuals With FVIII Inhibitors

Hematologic Diseases | Blood Coagulation Disorders, Inherited | Coagulation Protein Disorders | Hemorrhagic Disorders | Genetic Diseases, Inborn | Genetic Diseases, X-Linked | Gene Therapy | Blood Coagulation Disorder | Gene Transfer | Adeno-Associated Virus (AAV) | Factor VIII (FVIII) | Factor VIII (FVIII)... and other conditions

United States
Royal Marsden NHS Foundation Trust

Completed

Low-Fiber Diet or High-Fiber Diet in Preventing Bowel Side Effects in Patients Undergoing Radiation Therapy for Gynecological Cancer, Bladder Cancer, Colorectal Cancer, or Anal Cancer

Sarcoma | Cervical Cancer | Colorectal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Bladder Cancer | Anal Cancer | Radiation Toxicity | Gastrointestinal Complications

United Kingdom
Holy Name Medical Center, Inc.

Completed

Trial of Cytoreductive Surgery and HIPEC in Patients With Primary and Secondary Peritoneal Cancers

Cervical Cancer | Stomach Cancer | Colorectal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Carcinoma | Uterine Cancer | Appendiceal Cancer

United States
Universitaire Ziekenhuizen KU Leuven

Completed

Registry With Information About Colitis Ulcerosa and Familial Adenomatous Polyposis Patients (KOPOF)

Adenomatous Polyposis Coli | Colitis,Ulcerative | Reservoir, Ileoanal

Belgium
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

Ravuconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Stem Cell Transplantation

Lymphoma | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma | Infection | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Atezolizumab and Bevacizumab in Treating Patients With Rare Solid Tumors

Recurrent Peritoneal Malignant Mesothelioma | Recurrent Pleural Malignant Mesothelioma | Vaginal Squamous Cell Carcinoma, Not Otherwise Specified | Neuroendocrine Carcinoma | Pancreatic Neuroendocrine Tumor | Recurrent Merkel Cell Carcinoma | Recurrent Nasopharynx Carcinoma | Appendix Adenocarcinoma and other conditions

United States
Capital Medical University

Recruiting

Oncolytic Virus Ad-TD-nsIL12 for Progressive Pediatric Diffuse Intrinsic Pontine Glioma

Diffuse Intrinsic Pontine Glioma | Adverse Drug Event | Oncolytic Virus

China
Capital Medical University

Recruiting

Oncolytic Virus Ad-TD-nsIL12 for Primary Pediatric Diffuse Intrinsic Pontine Glioma

Diffuse Intrinsic Pontine Glioma | Adverse Drug Event | Oncolytic Virus

China
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Terminated

Moxifloxacin in Preventing Bacterial Infections in Patients Who Have Undergone Donor Stem Cell Transplant

Lymphoma | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma | Infection | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
University Hospital, Ghent
University Ghent; Kom Op Tegen Kanker

Recruiting

Intraperitoneal Aerosolized Nanoliposomal Irinotecan (Nal-IRI) in Peritoneal Carcinomatosis From Gastrointestinal Cancer (PIPAC-NAL-IRI)

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Small Bowel Cancer | Bile Duct Cancer | Peritoneal Carcinomatosis | Peritoneal Metastases | Appendix Cancer

Belgium
Compugen Ltd

Recruiting

COM902 (A TIGIT Inhibitor) in Subjects With Advanced Malignancies

Multiple Myeloma | Ovarian Cancer | Lung Cancer | Advanced Cancer | Colon Cancer | Plasma Cell Neoplasm | HNSCC | Microsatellite Stable Colorectal Carcinoma | MSS-CRC

United States
Cancer Trials Ireland

Completed

Study of Blood Samples From Patients With Malignant Melanoma, Metastatic Breast Cancer, Advanced Lung Cancer, Pancreatic Cancer, or Colorectal Cancer.

Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Lung Cancer | Melanoma (Skin)

Ireland
Pfizer

Completed

Study to Assess the Safety and Tolerability of Repeated Doses of an Investigational New Drug in Patients With Cancer and Cachexia.

Colorectal Cancer | Pancreatic Cancer | Cachexia | Non-Small-Cell Lung Cancer

United States
Celldex Therapeutics

Completed

Phase I Study of CDX-1307, hCG-B Vaccine, for Patients With Incurable, Locally Advanced or Metastatic Breast, Colorectal, Pancreatic, Bladder or Ovarian Cancer (CDX1307-02)

Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Bladder Cancer

United States
A2 Biotherapeutics Inc.
Tempus AI

Recruiting

A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Subjects With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression (EVEREST-1)

Cancer | Colorectal Neoplasms | Colorectal Cancer | Pancreatic Neoplasms | Pancreatic Cancer | NSCLC | Solid Tumor | Non Small Cell Lung Cancer | Colorectal Cancer Metastatic | Pancreas Cancer | Colorectal Adenocarcinoma | Solid Tumor, Adult | CRC | NSCLC, Recurrent | Non Small Cell Lung Cancer Recurrent | Non-Small Cell...

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Disease Management Program or Usual Care in Patients With Stage III or Stage IV Lung Cancer, Pancreatic Cancer, Ovarian Cancer, or Colorectal Cancer, and Their Caregivers

Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Lung Cancer

United States
Rigshospitalet, Denmark
Copenhagen University Hospital - Rigshospitalet, Department of Occupational... and other collaborators

Recruiting

The SaVe Project-Sarcopenia and Vertigo in Aging Patients With Colorectal Cancer (SaVe)

Cancer | Colorectal Cancer | Chemotherapy | Exercise | Sarcopenia | Vertigo | Rehabilitation | Elderly | Older Adults | Resistance Training | Geriatric | Chemotherapy-induced Peripheral Neuropathy | Vestibular Rehabilitation | Oncologic Complications | Comprehensive Geriatric Assessment | Frail | Postural Stability | Balance... and other conditions

Denmark
Boehringer Ingelheim

Recruiting

A Study Evaluating Different Doses of BI 765049 When Given Alone and When Given With Ezabenlimab to Patients With Advanced Solid Tumors Expressing the Protein B7-H6 on the Cell Surface

Colorectal Neoplasms, Carcinoma, Non-Small-Cell Lung, Pancreatic Neoplasms, Carcinoma, Hepatocellular, Head and Neck Neoplasms, Gastrointestinal Neoplasms

United States, Canada
Memorial Sloan Kettering Cancer Center

Recruiting

Researching the Effect of Exercise on Cancer

Breast Cancer | Colorectal Cancer | Prostate Cancer | Stage I Breast Cancer | Stage II Breast Cancer | Stage I Prostate Cancer | Stage II Prostate Cancer | Stage III Prostate Cancer | Stage III Breast Cancer | Stage III Colorectal Cancer | Stage I Colorectal Cancer | Stage II Colorectal Cancer

United States
Nektar Therapeutics

Completed

Study of NKTR 255 in Combination With Cetuximab in Solid Tumors

Cervical Cancer | Colorectal Cancer | Head and Neck Squamous Cell Carcinoma | Anal Squamous Cell Carcinoma | Cutaneous Squamous Cell Carcinoma

United States
Evelo Biosciences, Inc.
Merck Sharp & Dohme LLC; SCRI Development Innovations, LLC

Completed

A Study of EDP1503 in Patients With Colorectal Cancer, Breast Cancer, and Checkpoint Inhibitor Relapsed Tumors

Renal Cell Carcinoma | Non Small Cell Lung Cancer | Bladder Cancer | Triple Negative Breast Cancer | Colorectal Cancer Metastatic | GastroEsophageal Cancer | MSI-H

United States, Canada
University of California, Los Angeles

Completed

Primary Care Clinical Excellence Incentive Study (PCCE)

Diabetes | Cervical Cancer Screening | Primary Health Care | Behavioral Economics | Colorectal Cancer Screening | Health Maintenance | Chlamydia Screening | HPV Screening

United States
RemeGen Co., Ltd.

Recruiting

A RC198 Study in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors

Melanoma | Renal Cell Carcinoma | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Urothelial Carcinoma | Colorectal Carcinoma

Australia, China
Janux Therapeutics

Recruiting

Study of JANX008 in Subjects With Advanced or Metastatic Solid Tumor Malignancies

Renal Cell Carcinoma | Non-Small Cell Lung Cancer | Squamous Cell Carcinoma of the Head and Neck | Colorectal Carcinoma

United States
Julie L. Sutcliffe, Ph.D
National Cancer Institute (NCI)

Active, not recruiting

First-in-Human Positron Emission Tomography Study Using the 18F-αvβ6-Binding-Peptide

Breast Carcinoma | Lung Carcinoma | Colorectal Carcinoma | Pancreatic Carcinoma | Metastatic Malignant Neoplasm in the Lung | Metastatic Malignant Neoplasm in the Breast | Metastatic Malignant Neoplasm in the Colon | Metastatic Malignant Neoplasm in the Rectum

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Everolimus and Vatalanib in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific | Recurrent Melanoma | Stage IV Melanoma | Gastrinoma | Glucagonoma | Insulinoma | Metastatic Gastrointestinal Carcinoid Tumor | Pancreatic Polypeptide Tumor | Recurrent Gastrointestinal Carcinoid Tumor | Recurrent Islet Cell Carcinoma | Somatostatinoma | Stage... and other conditions

United States
University of Wisconsin, Madison
National Cancer Institute (NCI)

Completed

Motexafin Gadolinium and Doxorubicin in Treating Patients With Advanced Cancer

Lymphoma | Leukemia | Breast Cancer | Head and Neck Cancer | Chronic Myeloproliferative Disorders | Colorectal Cancer | Small Intestine Cancer | Lung Cancer | Prostate Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases

United States
National Cancer Institute (NCI)

Completed

A Broad Multi-histology Phase II Study of the Multi-Kinase Inhibitor R935788 (Fostamatinib Disodium) in Advanced Colorectal, Non-small Cell Lung, Head and Neck Hepatocellular and Renal Cell Carcinomas, and Pheochromocytoma and Thyroid Tumors (Multi-H...

Carcinoma, Renal Cell | Head and Neck Neoplasms | Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Pheochromocytoma

United States
Sanford Health
National Ataxia Foundation; Beyond Batten Disease Foundation; Pitt Hopkins Research... and other collaborators

Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)

Mitochondrial Diseases | Retinitis Pigmentosa | Myasthenia Gravis | Eosinophilic Gastroenteritis | Multiple System Atrophy | Leiomyosarcoma | Leukodystrophy | Anal Fistula | Spinocerebellar Ataxia Type 3 | Friedreich Ataxia | Kennedy Disease | Lyme Disease | Hemophagocytic Lymphohistiocytosis | Spinocerebellar Ataxia... and other conditions

United States, Australia
University of Toronto

Active, not recruiting

Family History App in Personalized Medicine (FHAMe)

Coronary Artery Disease | Melanoma | Diabetes Mellitus, Type 2 | Cancer, Breast | Cancer, Prostate | Cancer, Ovarian | Cancer, Colorectal

Canada
Foundation Fighting Blindness

Recruiting

Inherited Retinal Degenerative Disease Registry (MRTR)

Retinitis Pigmentosa | Choroideremia | Usher Syndrome | Batten Disease | Leber Congenital Amaurosis | Goldmann-Favre Syndrome | Kearns-Sayre Syndrome | Retinal Disease | Bardet-Biedl Syndrome | Stargardt Disease | Cone Dystrophy | Retinoschisis | Achromatopsia | Gyrate Atrophy | Eye Diseases Hereditary | Bassen-Kornzweig... and other conditions

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Genetic Mutations in Blood and Tissue Samples in Predicting Response to Treatment in Patients With Locally Advanced Rectal Cancer Undergoing Chemoradiation

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Recurrent Rectal Cancer

United States
Albert Einstein College of Medicine
National Cancer Institute (NCI)

Completed

Yoga-Based Rehabilitation Program in Reducing Physical and Emotional Side Effects in Patients With Cancer

Depression | Pain | Fatigue | Sleep Disorder | Anxiety | Breast Carcinoma | Lung Carcinoma | Alopecia | Colorectal Carcinoma | Nausea and Vomiting | Weight Change | Cognitive Side Effects of Cancer Therapy | Psychological Impact of Cancer

United States
Eli Lilly and Company
Merck Sharp & Dohme LLC; Loxo Oncology, Inc.

Recruiting

Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Pancreatic Neoplasms | Ovarian Neoplasms | Endometrial Neoplasms | Biliary Tract Neoplasms

Canada, United States, Japan, Australia, France, Korea, Republic of
Royal Marsden NHS Foundation Trust

Recruiting

Inherited Cancer Early Diagnosis (ICED) Study (ICED)

Lynch Syndrome | Familial Adenomatous Polyposis | Hereditary Diffuse Gastric Cancer | Peutz-Jeghers Syndrome | Cowden Syndrome | Li Fraumeni Syndrome | MutYH-associated Polyposis | SMAD4 Gene Mutation

United Kingdom
TILT Biotherapeutics Ltd.
Merck Sharp & Dohme LLC

Recruiting

Oncolytic Adenovirus TILT-123 With Pembrolizumab as Treatment for Ovarian Cancer (PROTA)

Platinum-resistant Ovarian Cancer | Platinum-Resistant Fallopian Tube Carcinoma | Platinum-Resistant Primary Peritoneal Carcinoma | Platinum-Refractory Fallopian Tube Carcinoma | Platinum-Refractory Primary Peritoneal Carcinoma | Platinum-refractory Ovarian Carcinoma | Platinum-Sensitive Ovarian... and other conditions

United States, Finland
Brigham and Women's Hospital
Northeastern University

Completed

Patient Safety Learning Laboratory: Making Acute Care More Patient-Centered (PSLL)

Venous Thromboembolism | Patient Fall | Adverse Drug Event | Severe Hypoglycemia | Hospital Acquired Pressure Ulcer | Central Line-Associated Bloodstream Infection (CLABSI) | Catheter-Associated Infection | Opioid-Related Severe Adverse Drug Event | Severe Hospital Acquired Delerium | Rapid Response Related...

United States
National Cancer Institute (NCI)

Completed

Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Locally Advanced Rectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Adenocarcinoma of the Rectum

United States
University Of Perugia

Unknown

ONE WEEK VERSUS FOUR WEEK HEPARIN PROPHYLAXIS AFTER LAPAROSCOPIC SURGERY FOR COLORECTAL CANCER. (PRO-LAPS I)

The Primary Study Objective is to Assess the Efficacy and | Safety of Extended 4-week Heparin Prophylaxis Compared to | Prophylaxis Given for 8±2 Days After Planned Laparoscopic | Surgery for Colorectal Cancer. | The Clinical Benefit Will be Evaluated as the Difference in | the Incidence of... and other conditions

Italy
Incyte Corporation

Active, not recruiting

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors

Cervical Cancer | Nasopharyngeal Carcinoma | Advanced Solid Tumors | Mesothelioma | Small-cell Lung Cancer | Esophageal Squamous Cell Carcinoma | Merkel Cell Carcinoma | Sarcomatoid Renal Cell Carcinoma | Anal Carcinoma | Cutaneous Squamous Cell Carcinoma | MSI-H/dMMR Tumors | PD-L1 Amplified Tumor (9p24.1) | Urothelial... and other conditions

Finland, United States, United Kingdom, Belgium, Sweden, Denmark, Norway
Virginia Commonwealth University
National Cancer Institute (NCI)

Completed

Phase I Study of Neoadjuvant Radiotherapy With 5-Fluorouracil for Rectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Rectal Adenocarcinoma | Recurrent Rectal Cancer

United States
King's College London

Recruiting

The Living With a Long-Term Condition Study (LTC)

Liver Diseases | Heart Diseases | Heart Failure | Stroke | Cerebrovascular Disorders | Epilepsy | Pain | Multiple Sclerosis | Hypertension | Obesity | Diabetes | Cancer | Arthritis | Osteoarthritis | Rheumatoid Arthritis | Parkinson Disease | Migraine | Hepatitis | Atrial Fibrillation | Asthma | Endometriosis | Dementia | Fibromyalgia | Celiac... and other conditions

United Kingdom
Emory University
National Cancer Institute (NCI); Merck Sharp & Dohme LLC; National Institutes... and other collaborators

Completed

Pembrolizumab and XL888 in Patients With Advanced Gastrointestinal Cancer

Unresectable Pancreatic Carcinoma | Metastatic Pancreatic Adenocarcinoma | Recurrent Pancreatic Carcinoma | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Recurrent Colorectal Carcinoma | Colorectal Adenocarcinoma | Stage IV Colorectal Cancer | Stage IVA Colorectal Cancer | Stage IVA Pancreatic... and other conditions

United States
NGM Biopharmaceuticals, Inc
Merck Sharp & Dohme LLC

Recruiting

Study of NGM831 as Monotherapy and in Combination With Pembrolizumab or Pembrolizumab and NGM438 in Advanced or Metastatic Solid Tumors

Melanoma | Renal Cell Carcinoma | Cervical Cancer | Breast Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Prostate Cancer | Mesothelioma | Squamous Cell Carcinoma of Head and Neck | Cholangiocarcinoma | Non-small Cell Lung Cancer | Colorectal Carcinoma | Bladder Urothelial Cancer | Endocervical...

United States
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Recruiting

Peritoneal Carcinomatosis Leveraging ctDNA Guided Treatment in GI Cancer Study (PERICLES Study)

Peritoneal Carcinomatosis | Digestive System Neoplasm | Liver and Intrahepatic Bile Duct Carcinoma | Appendix Carcinoma by AJCC V8 Stage | Colorectal Carcinoma by AJCC V8 Stage | Esophageal Carcinoma by AJCC V8 Stage | Gastric Carcinoma by AJCC V8 Stage

United States
Emory University
National Cancer Institute (NCI); National Institutes of Health (NIH); Vaccinex...

Completed

VX15/2503 and Immunotherapy in Resectable Pancreatic and Colorectal Cancer

Pancreatic Adenocarcinoma | Stage III Pancreatic Cancer | Colorectal Adenocarcinoma | Stage IIA Pancreatic Cancer | Stage IIB Pancreatic Cancer | Stage II Pancreatic Cancer | Stage IV Colorectal Cancer | Stage IVA Colorectal Cancer | Stage IVB Colorectal Cancer | Stage I Pancreatic Cancer | Resectable Pancreatic... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Trametinib and Trifluridine and Tipiracil Hydrochloride in Treating Patients With Colon or Rectal Cancer That is Advanced, Metastatic, or Cannot Be Removed by Surgery

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Metastatic Colorectal Carcinoma | Stage III Colon Cancer AJCC v7 | Stage III Rectal Cancer AJCC v7 | Stage IIIA Colon Cancer AJCC v7 | Stage IIIA Rectal Cancer AJCC v7 | Stage IIIB Colon... and other conditions

United States
AbbVie

Terminated

A Study Evaluating Safety and Pharmacokinetics of ABBV-221 in Subjects With Advanced Solid Tumor Types Likely to Exhibit Elevated Levels of Epidermal Growth Factor Receptor

Glioblastoma Multiforme | Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Colorectal Carcinoma

United States, Spain

Clinical Trials on Chronic Graft-versus-host Disease

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Thailand

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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