Clinical Trials on Chronic Instability of Knee Joint in South Africa

Total 256 results

Cleveland Chiropractic College
Durban University of Technology

Unknown

Comparing Manipulation and Rehabilitation to Rehabilitation Only, in the Management of Chronic Ankle Instability

Chronic Ankle Instability

South Africa
Aesculap AG
Raylytic GmbH

Recruiting

In-vivo Wear Behaviour of AS Coated Versus Uncoated Columbus® Total Knee Prosthesis (COLRAS)

Knee Osteoarthritis | Osteonecrosis | Knee Arthritis | Instability, Joint | Rheumatoid Arthritis of Knee | Deformity Knee | Primary Osteoarthritis of Knee Nos | Secondary Osteoarthritis of Knee Nos

Australia, Germany
University of Witwatersrand, South Africa

Completed

Habitual Physical Activity and Sedentary Behavior Following Total Knee Arthroplasty

Knee Osteoarthritis

South Africa
Janssen Research & Development, LLC

Completed

A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JNJ-39439335 in Patients With Osteoarthritis

Osteoarthritis, Knee

South Africa
University of Cape Town

Completed

Study of Hip and Knee Arthroplasty in South Africa

Arthritis, Rheumatoid | Osteoarthritis, Knee | Osteoarthritis, Hip | Arthritis Knee | Arthritis of Hip

South Africa
Medical University of South Carolina

Completed

Evaluation of the Duration of Bupivacaine Spinal Block in Orthopedic Procedures With and Without Epinephrine Wash

Arthropathy of Knee | Arthropathy of Hip

United States
Cleveland Chiropractic College
Durban University of Technology; Murdoch University

Completed

Comparing Manipulation, Rehabilitation and Combination of the Two in the Treatment of Knee Osteoarthritis

Osteoarthritis, Knee

United States, South Africa
Ampio Pharmaceuticals. Inc.

Completed

AP-003-C Study to Confirm the Efficacy of Ampion™ in Adults With Pain Due to Severe Osteoarthritis of the Knee

Knee Osteoarthritis | Osteoarthritis, Knee | Knee Arthritis | Knee Pain Chronic

United States
University of Vermont

Completed

Mobile Technology to Support Physical Therapy Exercise (MyTherEx)

Osteoarthritis of Knee | Osteoarthritis Of Hip

United States
Zimmer Biomet

Recruiting

Clinical Outcomes Study of the Nexel Total Elbow

Post-traumatic Arthritis | Degenerative Arthritis | Elbow Joint Destruction | Post-traumatic Lesions | Ankylosed Joints | Advanced Rheumatoid Arthritis | Joint Instability or Loss of Motion | Acute Comminuted Articular Fracture of Elbow Joint Surfaces | Bone Loss Contributing to Elbow Instability | Bilateral...

United States, Australia, Finland, France, Germany, Italy, Netherlands, United Kingdom
University of Stellenbosch
National Research Foundation of South Africa

Completed

Joint Position Sense in Individuals With Anterior Knee Pain

Proprioceptive Disorders | Anterior Knee Pain Syndrome

South Africa
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Patient Specific Instrumentation in TKR

Osteoarthritis of the Knee

United Kingdom
Taiwan Liposome Company

Completed

A Phase 2, Open Label, PK Study of TLC599 in Subject With Osteoarthritis of the Knee

OSTEOARTHRITIS OF THE KNEE

Taiwan, United States
Pacira Pharmaceuticals, Inc

Completed

Pharmacokinetic and Pharmacodynamic Study of FX006 in Patients With Osteoarthritis of the Knee

Osteoarthritis of the Knee

Australia
Helen Joseph Hospital
University of Johannesburg; Abbott Point of Care; Lodox Systems (Ltd)

Completed

Early Point-Of-Care Blood Tests, ECG & X-rays in the Emergency Department (EPOC-BEX-ED)

Emergency Medicine | Point-of-Care Testing

South Africa
GlaxoSmithKline

Completed

Effectiveness Of Single Doses Of Ibuprofen In Patients With Osteoarthritis Of The Knee

Osteoarthritis

Australia
Smith & Nephew, Inc.

Completed

Visionaire Health Economics Study Comparing Economic Outcomes Between Visionaire and Standard Instrumentation (VISHE13)

Osteoarthritis, Knee

South Africa
Xgene Pharmaceutical Group
Novotech (Australia) Pty Limited

Completed

A Study of Topical XG004 in Participants With Osteoarthritis of the Knee

Pain

Australia
University of South Carolina

Terminated

NEAT!2 Sedentary Behavior Reduction for Individuals With Past or Present Knee Symptoms, Injuries, or Surgeries

Sedentary Lifestyle | Knee Osteoarthritis | Knee Injuries | Knee Pain Chronic

United States
AstraZeneca

Completed

A Study of the Efficacy and Safety of MEDI7352 in Subjects With Painful Osteoarthritis of the Knee (BESPOKE)

Painful Osteoarthritis of the Knee

Spain, United Kingdom, South Africa, Poland, Estonia, Denmark, Germany
Tris Pharma, Inc.
Forest Laboratories

Completed

Safety and Efficacy Study of GRT6005 in Patients With Osteoarthritis (OA) Knee Pain

Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee

United States
Prisma Health-Midlands

Terminated

Astaxanthin for Management of Inflammation in Knee Osteoarthritis

Osteoarthritis, Knee | Osteoarthritis Knees Both | Joint Inflammation

United States
Olatec Therapeutics LLC

Completed

Phase 2 Efficacy Trial of OLT1177 Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee

Osteoarthritis of the Knee

United States
Carolyn M Hettrich
University of Colorado, Denver; Washington University School of Medicine; University... and other collaborators

Recruiting

MOON Shoulder Instability-Cohort of Patients Undergoing Operative Treatment. (MOONSI)

Other Instability, Shoulder | Dislocations | Subluxations | Recurrent Dislocation of Shoulder Region

United States
Ampio Pharmaceuticals. Inc.

Terminated

Open Label Extension to Assess the Safety of Long-Term Treatment With Ampion for Severe Osteoarthritis (OA) of the Knee

Severe Osteoarthritis of the Knee

United States
Merck KGaA, Darmstadt, Germany
Merck Serono S.A., Geneva

Completed

Study of AS902330 (rhFGF-18) Administered Intra-articularly in Patients With Knee Primary Osteoarthritis Who Are Candidates for Total Knee Replacement

Knee Osteoarthritis

Denmark, Finland, Sweden, United Kingdom, Bulgaria, South Africa
DePuy International

Terminated

A Single Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Primary Hip Resurfacing Surgery

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Nonunion of Femoral Fractures

South Africa
Unity Biotechnology, Inc.

Completed

A Study of Single and Repeat Dose Administration of UBX0101 in Patients With Osteoarthritis of the Knee

Knee Osteoarthritis

United States
Carbylan Therapeutics, Inc.

Completed

Hydros and Hydros-TA Joint Therapy for Pain Associated With Knee Osteoarthritis

Osteoarthritis of the Knee

Canada, Australia, Netherlands Antilles
Duke University
Orthopedic Research and Education Foundation; American Association of Hip and...

Recruiting

Antibiotic Prophylaxis in Patients Undergoing Elective TKA- Multi-center Trial

Arthropathy of Knee | Antibiotic Prophylaxis

United States
Harokopio University

Completed

The Effect of Phenolic Compounds in Osteoarthritis; a Nutritional Intervention

Symptomatic Knee Osteoarthritis

Greece
Novartis

Completed

Efficacy and Safety of Lumiracoxib in Patients With Primary Knee Osteoarthritis (OA)

Osteoarthritis

Czech Republic, Germany, Finland, Hungary, Australia, Austria, Turkey, Poland, Israel, Spain, South Africa, Slovakia, Sweden, Netherlands, New Zealand
IDEA AG

Completed

Study of Safety and Efficacy of Diractin® for the Treatment of Osteoarthritis (OA) of the Knee

Osteoarthritis of the Knee

United States
Regeneron Pharmaceuticals
Teva Pharmaceutical Industries, Ltd.

Completed

Long-Term Safety and Efficacy Study of Fasinumab in Patients With Pain Due to Osteoarthritis (OA) of the Knee or Hip (FACT LTS & OA)

Osteoarthritis of the Knee or Hip

United States, Bulgaria, Chile, Colombia, Denmark, Estonia, Germany, Hong Kong, Hungary, Italy, Lithuania, Mexico, Peru, Poland, Romania, Russian Federation, South Africa, Spain, Sweden, Ukraine, United Kingdom
Avanos Medical

Completed

Coolief Cooled Radiofrequency vs. Conventional Radiofrequency to Manage OA Knee Pain

Osteoarthritis of the Knee

United States
Organogenesis
Premier Research Group plc

Active, not recruiting

Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee

Knee Osteoarthritis

United States
Arrevus Inc.

Terminated

Safety and Efficacy of CEM-102 With Rifampin Compared to Standard Therapy in Patients With Prosthetic Joint Infections or Spacer Infection

Prosthetic Joint Infections of Hip | Prosthetic Joint Infections of Knee | Infected Spacers

United States
University of Cape Town
King's College London; University of KwaZulu

Completed

Collaborative Care for the Detection and Management of Depression Among Adults Receiving Antiretroviral Therapy in South Africa (COBALT)

Depression | HIV/AIDS | Chronic Diseases of Lifestyle

South Africa
Organogenesis

Recruiting

A Study to Evaluate the Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee

Knee Osteoarthritis

United States
Merck KGaA, Darmstadt, Germany

Completed

A Multicenter Study of rhFGF 18 in Patients With Knee Osteoarthritis Not Requiring Surgery

Knee Osteoarthritis

Germany, Croatia, Bulgaria, Canada, Finland, Poland, Serbia, South Africa, Sweden
Unity Biotechnology, Inc.

Terminated

Long-Term Follow-Up Study of Patients With Osteoarthritis of the Knee Treated With UBX0101 or Placebo

Knee Osteoarthritis

United States
Cubist Pharmaceuticals LLC
Pfizer

Completed

Efficacy and Safety Study Evaluating ADL5859 and ADL5747 in Participants With Pain Due to Osteoarthritis of the Knee

Osteoarthritis of the Knee

United States
Mallinckrodt

Completed

Exploratory Study of PENNSAID Gel to Treat Symptoms of Knee Osteoarthritis

Osteoarthritis of the Knee

United States
Genzyme, a Sanofi Company

Completed

Comparison of Hylastan to Methylprednisolone Acetate in Patients With Symptomatic Osteoarthritis of the Knee

Osteoarthritis, Knee

United States, Canada, France, Germany, United Kingdom
Halyard Health

Completed

Nerve Ablation by Cooled Radiofrequency Compared to Corticosteroid Injection for Management of Knee Pain

Osteoarthritis of the Knee

United States
Zimmer Biomet
Medical Metrics Diagnostics, Inc; MedNet Solutions

Completed

Subchondroplasty® Knee RCT (PRESERVE Knee)

Osteoarthritis | Knee Osteoarthritis | Osteoarthritis, Knee | Bone Marrow Edema | Knee Pain Chronic

United States, Canada
Grünenthal GmbH

Recruiting

Open-label Trial to Check the Safety and Tolerability of RTX-GRT7039 Injections for Pain Associated With Osteoarthritis of the Knee

Osteoarthritis

Japan, United States, South Africa, Bulgaria, Poland, Romania, United Kingdom
Avanos Medical

Completed

Cooled Radiofrequency vs. Hyaluronic Acid to Manage Knee Pain

Osteoarthritis of the Knee

United States
Canary Medical

Recruiting

Quantitative Assessment of Walking (Squawk) With the Canary canturioTM te (CTE) Tibial Extension

Arthritis Knee

United States
Regeneron Pharmaceuticals

Terminated

A Study to Examine the Efficacy and Safety of REGN5069 in Patients With Pain Due to Osteoarthritis of the Knee

Pain | Osteoarthritis of the Knee

United States, Georgia, Moldova, Republic of, Poland, Ukraine

Clinical Trials on Chronic Instability of Knee Joint in South Africa

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