Clinical Trials on Chronic Liver Disease in South Africa

Total 18766 results

GlaxoSmithKline
Aeras

Completed

Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine in Healthy HIV Negative Adolescents

Tuberculosis

South Africa
Massachusetts General Hospital
National Institute of Allergy and Infectious Diseases (NIAID); AIDS Healthcare...

Completed

Test and Treat TB: A Proof of Concept Trial in South Africa (Siyasiza)

Tuberculosis

South Africa
Boston Children's Hospital
National Institute of Mental Health (NIMH); National Institutes of Health (NIH)

Completed

A South African Pilot Worksite Parenting Program to Prevent HIV Among Adolescents

Parent-Child Relations

South Africa
Aeras
Crucell Holland BV

Completed

Safety and Immunogenicity of AERAS-402 in HIV-infected, Bacillus Calmette-Guerin (BCG)-Vaccinated Adults

HIV Infections | Tuberculosis

South Africa
Enyo Pharma

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of EYP001a in Healthy Volunteers and Nonalcoholic Steatohepatitis Patients

Healthy | NASH - Nonalcoholic Steatohepatitis

Australia
Aeras
Crucell Holland BV

Completed

A Study to Evaluate the Safety of AERAS-402 in Adults Recently Treated for Pulmonary TB (C-010-402)

Tuberculosis

South Africa
Sequella, Inc.

Completed

PNU-100480 In Newly Diagnosed, Drug Sensitive Patients With Pulmonary TB; Early Bactericidal Activity; Whole Blood Assay

Tuberculosis

South Africa
Clover Biopharmaceuticals AUS Pty Ltd

Completed

Safety and Immunogenicity Dose-finding Study of Adjuvanted SCB-2020S Vaccine in Adults

COVID-19

South Africa
University of Cape Town

Completed

Impact of Employee Wellness Programme

Obesity

South Africa
Massachusetts General Hospital
National Institute of Mental Health (NIMH); National Institutes of Health (NIH) and other collaborators

Completed

Safer Conception for Women - Understanding Use of Periconception PrEP

HIV Prevention | Conception

South Africa
Medical University of South Carolina

Completed

Portal Blood Flushes in the Peri-Reperfusion Stage of Liver Transplantation

Liver Disease

United States
Foundation for Innovative New Diagnostics, Switzerland
Ludwig-Maximilians - University of Munich; Heidelberg University; Swiss Tropical... and other collaborators

Active, not recruiting

TB-CAPT MTB/XDR Study

Tuberculosis | Diagnoses Disease | Resistance Bacterial

South Africa
Centre for the AIDS Programme of Research in South...

Completed

Improving Retreatment Success (IMPRESS) (IMPRESS)

Recurrent Tuberculosis

South Africa
GlaxoSmithKline

Completed

Study of Sequential GSK3228836 and Peginterferon Treatment in Participants With Chronic Hepatitis B (CHB) (B-Together)

Hepatitis B

Russian Federation, Spain, Canada, China, United States, Italy, Japan, Korea, Republic of, Poland, South Africa, United Kingdom
University of KwaZulu
Centre for the AIDS Programme of Research in South Africa

Recruiting

Pharmacokinetics of Twice or Once Daily DTG (50mg) in Children With HIV and TB (ORCHID)

Tuberculosis | Hiv

South Africa
GlaxoSmithKline

Completed

Bioequivalence Study Between SKF101804 Cefixime 200 Milligram (mg)/5 Milliliter (mL) Suspension Versus Cefixime 200 mg/5 mL Suspension Reference Product in Healthy Adult Subjects Under Fasting Conditions

Infections, Bacterial

South Africa
University of Illinois at Chicago
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

A Comprehensive HIV Prevention Package for South African Adolescent Girls and Young Women: IMARA SA (IMARA-SA pilot)

Hiv | Sexually Transmitted Infection

South Africa
Columbia University
Centre for the AIDS Programme of Research in South Africa

Not yet recruiting

An Adaptive Randomized Controlled Trial (ADAP-TIV)

HIV Infections | Multi Drug Resistant Tuberculosis

South Africa
University of Stellenbosch
University of Rochester; Fogarty International Center of the National Institute...

Recruiting

A Pilot Study of Metformin to Reduce Cerebrovascular Dysfunction in Participants With HIV and Metabolic Syndrome. (SMART)

Metabolic Syndrome | HIV Seropositivity

South Africa
Centre for the AIDS Programme of Research in South...
Institute for Healthcare Improvement; BroadReach Health Care

Completed

Scaling up TB and HIV Treatment Integration (SUTHI)

HIV | Tuberculosis

South Africa
Centre for the AIDS Programme of Research in South...

Completed

A Study to Compare Three Existing Starting Points of Anti-Retroviral Therapy (ART) Initiation in HIV/Tuberculosis (TB) Co-infected Patients (SAPIT)

HIV Infections | Tuberculosis

South Africa
University of Stellenbosch

Unknown

The Utility of Radiotherapy in the Management of Haemoptysis Secondary to Aspergillomata and Structural Lung Diseases

Haemoptysis

South Africa
Debiopharm International SA

Completed

Efficacy and Safety of a Triptorelin 6-month Formulation in Patients With Advanced Prostate Cancer

Prostatic Neoplasm

South Africa
Biofabri, S.L
University of Stellenbosch; University of Cape Town; TuBerculosis Vaccine Initiative and other collaborators

Recruiting

Efficacy, Safety and Immunogenicity Evaluation of MTBVAC in Newborns in Sub-Saharan Africa (MTBVACN3)

Tuberculosis

South Africa
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

Drug-drug Interaction Study With MDV3100 and a Cocktail of Substrates

Castration Resistant Prostate Cancer (CRPC) | Pharmacokinetics of MDV3100

South Africa
University of KwaZulu
University of California, San Francisco; Centers for Disease Control and Prevention and other collaborators

Completed

Effectiveness of an HIV-adapted IMCI Training and Supervision Programme for Community Health Workers

Infant Feeding Practices | Prevention of Mother-to-child Transmission of HIV | Antenatal Health Care Utilization | Postnatal Health Care Utilization

South Africa
Serum Institute of India Pvt. Ltd.
University of Stellenbosch; South African Tuberculosis Vaccine Initiative; Vakzine... and other collaborators

Completed

Study to Evaluate the Safety and Immunogenicity of VPM1002 in Comparison With BCG in HIV-exposed/-Unexposed Newborn Infants in South Africa

Tuberculosis

South Africa
Aeras
University of Oxford; University of Cape Town

Completed

A Study of MVA85A in Healthy Infants

Tuberculosis

South Africa
Novartis

Completed

A Crossover Study to Determine the Effect on Lung Function of Indacaterol in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD), Using Tiotropium as an Active Control

Chronic Obstructive Pulmonary Disease (COPD)

Spain, Germany, South Africa, Australia, Poland, New Zealand, Netherlands
RTI International
University of Cape Town

Completed

Treating South African Pregnant Women for Methamphetamine

HIV | Drug Addiction

South Africa
International Maternal Pediatric Adolescent AIDS...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

TASK-002: Bioequivalence of Bedaquiline 400mg Administered in Crushed Form Compared to Tablet Form in Healthy Male and Female Adults Under Fed Conditions (BDQ Crush Study)

Tuberculosis

South Africa
Duke University

Active, not recruiting

Reducing Disparities in the Quality of Advance Care Planning for Older Adults (EQUALACP)

End Stage Liver Disease | Diabetes Complications | Chronic Obstructive Pulmonary Disease | Parkinson Disease | Amyotrophic Lateral Sclerosis | End Stage Renal Disease | Metastatic Cancer | Interstitial Lung Disease | Congestive Heart Failure

United States
Novartis Pharmaceuticals

Completed

Adaptive-design Dose Finding Study to Assess the Antiviral Efficacy and Safety of NIM811 Administered in Combination With Standard of Care (SOC) in Relapsed Hepatitis C Virus 1 (HCV-1) Infected Patients

Chronic Hepatitis C Genotype-1 Relapse

Belgium, United States, Germany, Spain, Puerto Rico, Taiwan, Australia
Altimmune, Inc.

Completed

ALT-801 DDI Study in Healthy Volunteers

NASH - Nonalcoholic Steatohepatitis

Australia
Minervax ApS
European and Developing Countries Clinical Trials Partnership (EDCTP)

Completed

Study of a Group B Streptococcus Vaccine in Pregnant Women Living With HIV and in Pregnant Women Who do Not Have HIV

Group B Streptococcal Infection

South Africa, Uganda
Pfizer

Completed

An Open-label Study of APX001 for Treatment of Patients With Candidemia/Invasive Candidiasis Caused by Candida Auris (APEX)

Candidemia | Candida Infection | Invasive Candidiases

South Africa
GlaxoSmithKline

Completed

Restless Legs Patient Study On Absorption, Distribution, Metabolism And Excretion Of Ropinirole And The Effect Of Food

Restless Legs Syndrome

Germany, South Africa
University of Bern
University of Alabama at Birmingham; University of Southern California; Louisiana... and other collaborators

Active, not recruiting

Genital Tract Infections, the Vaginal Microbiome and Gestational Age at Birth Among Pregnant Women in South Africa

HIV Infections | Premature Birth | Microbial Colonization | Pregnancy; Infection | Bacterial Vaginosis | Trichomonas Vaginitis | Neisseria Gonorrheae Infection | Chlamydia Trachomatis Infection | Mycoplasma Genitalium Infection | Genital Mycoplasma Infection | Vaginal Candida | Sexually Transmitted Infections... and other conditions

South Africa
Kirby Institute

Recruiting

Enhancing Hepatitis C Testing and Treatment Among People Who Inject Drugs Attending Needle and Syringe Programs (TEMPO)

Hepatitis C | Hepatitis C, Chronic

Australia
Erasmus Medical Center
Rijndam Revalidatiecentrum; Capri Hartrevalidatie

Recruiting

PREoPerAtive pREhabilitation in Patients With Head and Neck Cancer or Liver Cancer (PREPARE) (PREPARE)

Cancer Head Neck | Cancer Liver

Netherlands
Brown University
Rhode Island Hospital; University of Cape Town; Medical Research Council, South... and other collaborators

Active, not recruiting

Our Family Our Future: A Resilience-oriented Family Intervention to Prevent Adolescent HIV/STI Infection and Depression in South Africa

Depression | Sexually Transmitted Diseases | Human Immunodeficiency Virus

South Africa
University of Cape Town
Imperial College London; Institute of Tropical Medicine, Belgium; European and... and other collaborators

Completed

Preventing TB-IRIS in High-risk Patients: a Randomized Placebo-controlled Trial of Prednisone (Pred-ART)

HIV | Tuberculosis | Immune Reconstitution Inflammatory Syndrome

South Africa
University of Cape Town
London School of Hygiene and Tropical Medicine; Johns Hopkins University; Imperial... and other collaborators

Completed

Isoniazid Plus Antiretroviral Therapy to Prevent Tuberculosis in HIV-infected Persons (HAART-IPT)

HIV Infections | Tuberculosis | Latent Tuberculosis Infection

South Africa
Hoffmann-La Roche

Completed

A Study of Continued Treatment Among Participants Who Have Responded to Peginterferon Alfa-2a (Pegasys®) or Recombinant Interferon Alfa-2a (Roferon-A®) in Prior Clinical Studies

Renal Cell Carcinoma | Chronic Myelogenous Leukemia | Malignant Melanoma

Canada, India, Bulgaria, Russian Federation, Spain, South Africa, Slovakia
Foundation for Professional Development (Pty) Ltd
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

Clinical Study of STI Screening to Prevent Adverse Birth and New-born Outcomes

HIV/AIDS | Pregnancy | Cost-effectiveness | Antenatal Care | Chlamydia Trachomatis | Vaginal Microbiome | Birth Outcomes | Sexually Transmitted Infection | Neisseria Gonorrhoeae | Trichomonas Vaginalis

South Africa
Bayer

Completed

HPA Axis Study in Adults

Eczema | Atopic Dermatitis

South Africa
South West Sydney Local Health District
National Health and Medical Research Council, Australia; University of Sydney

Completed

Baclofen in the Treatment of Alcohol Dependence With or Without Alcoholic Liver Disease (BacALD)

Alcohol Dependence | Alcoholic Liver Disease

Australia
Aretaieio Hospital

Unknown

The Effect of Volatile Anesthetics Sevoflurane and Desflurane on Liver, Renal and Cardiovascular Systems During Liver Surgery

Liver Surgery | Apoptosis

Greece
University of Cape Town
Population Health Research Institute; Walter Sisulu University

Unknown

IMPI 2 - A Trial of Intrapericardial Alteplase in Large Pericardial Effusion (IMPI-2)

Pericardial Effusion

South Africa
University of Stellenbosch
Columbia University; McMaster University

Active, not recruiting

Mobile Phone Text Messaging Plus Motivational Interviewing: Effects on Breastfeeding, Child Health Outcomes (MTM-MI)

HIV Infections | Breastfeeding, Exclusive

South Africa

Clinical Trials on Chronic Liver Disease in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Benin

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations