Clinical Trials on Chronic Lung Allograft Dysfunction (CLAD) in United Kingdom

Total 2435 results

London School of Hygiene and Tropical Medicine
University College, London; British Medical Research Council

Completed

Survival After First Myocardial Infarction in Patients With and Without Chronic Obstructive Pulmonary Disease

Myocardial Infarction | Chronic Obstructive Pulmonary Disease

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

The Effect of Two Weeks of Voluntary Reduced Physical Activity in Chronic Obstructive Pulmonary Disease (COPD)

Muscle Atrophy | Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
Novartis Pharmaceuticals

Completed

QVA Mechanistic Efficacy Study (Receptor Effects, Etc)

Chronic Obstructive Pulmonary Disease

United Kingdom
AstraZeneca

Completed

A Real-World Assessment of a COPD Disease Management Support Service (Me & My COPD) (Me&MyCOPD)

Chronic Obstructive Pulmonary Disease

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Completed

Use of Endobronchial Valves in Non-Upper Lobe Heterogeneous Emphysema

Heterogeneous Emphysema

United Kingdom
AstraZeneca
RTI Health Solutions

Completed

A Drug Utilisation Post-authorisation Study of New Users of Aclidinium Bromide (Monotherapy or in Combination) (DUS1/DUS2)

Pulmonary Disease, Chronic Obstructive

Denmark, Germany, United Kingdom
GlaxoSmithKline

Completed

A Study to Look at Day to Day Changes in Lung Function in COPD Subjects Taking Albuterol/Salbutamol and Ipratropium

Pulmonary Disease, Chronic Obstructive

United States, United Kingdom
Imperial College London

Unknown

Physiology and Structure of the Small Airways in Patients With Chronic Airflow Obstruction or COVID-19 (PASSPORT)

COVID-19 | Asthma | Copd | Small Airways Disease

United Kingdom
Duke University

Recruiting

At-Home Diaphragmatic Interventions for Voiding Abnormalities (DIVA) (DIVA)

Urinary Dysfunction | Dysfunctional Voiding

United States
Hull University Teaching Hospitals NHS Trust
Philips Respironics

Completed

Cough Frequency in Chronic Obstructive Pulmonary Disease

COPD Exacerbation

United Kingdom
Belfast Health and Social Care Trust
Queen's University, Belfast; Northern Ireland Clinical Trials Unit

Terminated

Epstein-Barr Virus Suppression in Chronic Obstructive Pulmonary Disease (EViSCO): a Phase 2 Randomised Control Trial (EViSCO)

COPD | EBV

United Kingdom
Imperial College London
Melinta Therapeutics, Inc.

Terminated

A Study to Evaluate the Anti-inflammatory Effects of Solithromycin in Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

United Kingdom
Queen Mary University of London

Completed

Skeletal Muscle Wasting and Renal Dysfunction After Critical Illness Trauma - Outcomes Study (KRATOS)

Quality of Life | Critical Illness | Chronic Kidney Diseases | Acute Kidney Injury | Muscle Loss | Major Trauma

United Kingdom
University College, London

Unknown

Mechanisms of COPD Exacerbation Recurrence

Recurrence | Pulmonary Disease, Chronic Obstructive | COPD Exacerbation | Patient Readmission

United Kingdom
Pfizer

Completed

A Study To Determine Effects Of Fluticasone Propionate On Sputum Neutrophils After Inhaled Lipopolysaccharide Challenge In Volunteers

Pulmonary Disease, Chronic Obstructive

United Kingdom
University of Dundee
AstraZeneca; NHS Tayside

Completed

Microbiome Use to Stratify Use of Inhaled Corticosteroids: MUSIC Trial (MUSIC)

Chronic Obstructive Pulmonary Disease

United Kingdom
GlaxoSmithKline

Completed

GSK159802 In Healthy Male Subjects And Asthmatics

Pulmonary Disease, Chronic Obstructive

United Kingdom
Northumbria Healthcare NHS Foundation Trust
Newcastle-upon-Tyne Hospitals NHS Trust; National Institute for Health Research... and other collaborators

Completed

Mortality and Symptom Burden Post Hospitalisation With COPD (MoSHCOPD)

Pulmonary Disease, Chronic Obstructive | Emphysema | Chronic Bronchitis | Pulmonary Disease, Obstructive | Chronic Bronchitis With Airways Obstruction | Chronic Bronchitis With Acute Exacerbation

United Kingdom
Maria Joyera Rodríguez

Not yet recruiting

Molecular Signatures Associated With Response to ICS Treatment in Patients With COPD Stratified by Eosinophil Levels (3TR-ICS-COPD)

Chronic Obstructive Pulmonary Disease

United Kingdom, Spain, Netherlands, Germany
GlaxoSmithKline

Completed

Repeat Dose Study in Male Healthy Volunteer Smokers

Pulmonary Disease, Chronic Obstructive

United Kingdom
National Institute of Diabetes and Digestive and...

Completed

Assessment of Insulin Production From Native Pancreas in Patients With Pancreas Transplants

Long-Functioning Pancreas Allografts | Pancreas Transplant

United States
Chiesi Farmaceutici S.p.A.

Completed

Phase II Study to Evaluate the Cardiac Safety of 2 Doses of CHF5993 Both Combined With CHF1535 BID Versus CHF1535 BID in Patients With Moderate to Severe COPD (CARSAF)

Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Bulgaria, Germany, Hungary, Poland, Russian Federation, United Kingdom
Apreo Health, Inc.

Recruiting

Study to Assess Safety, Feasibility, and Preliminary Efficacy of the Apreo Implant for Severe Emphysema (BREATHE-2)

Emphysema or COPD

United Kingdom, Austria, Netherlands
Boston Scientific Corporation
PneumRx, Inc.

Completed

Randomized Comparison of the RePneu Lung Volume Reduction Coil (LVRC) to Standard of Care for the Treatment of Emphysema (RESET Study)

Emphysema

United Kingdom
Pneumacare Ltd

Not yet recruiting

Structured Light Plethysmography Against Standard of Care in the Diagnosis and Monitoring of Dysfunctional Breathing (SLPDB)

Dysfunctional Breathing

United Kingdom
Royal Free Hospital NHS Foundation Trust
Fisher and Paykel Healthcare; Royal Free Charity

Active, not recruiting

Domiciliary Nasal High Flow and Patient Outcomes in Chronic Hypercapnic Respiratory Failure in the United Kingdom

Chronic Obstructive Pulmonary Disease | Chronic Hypercapnic Respiratory Failure | Health-related Quality of Life | Obesity Hypoventilation Syndrome (OHS) | Nasal High Flow

United Kingdom
Sheffield Hallam University
Symprove UK; Biomesight

Recruiting

Investigation of the Use of a Probiotic Supplement in People With Long COVID

Long COVID

United Kingdom
Heart of England NHS Trust
British Lung Foundation

Completed

Computed Tomography Assessment of Regional Ventilation (CURVE) (CURVE)

Lung Neoplasms | Pulmonary Disease, Chronic Obstructive | Emphysema | Lung Diseases, Interstitial

United Kingdom
Mannkind Corporation

Completed

A Study to Evaluate Insulin in the Blood After Inhalation of a Dry Powder Insulin Formulation (Called Technosphere®/Insulin) in Non-diabetic Patients With & Without Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

Netherlands, United States, Austria, United Kingdom
Novartis Pharmaceuticals

Terminated

A Proof-of-mechanism Study of Multiple, Oral Doses of Fevipiprant (QAW039) in COPD Patients With Eosinophilia

Chronic Obstructive Pulmonary Disease

Germany, United Kingdom
Papworth Hospital NHS Foundation Trust

Recruiting

RV Conductance Catheter Assessment During Balloon Pulmonary Angioplasty (RVBPA)

Chronic Thromboembolic Pulmonary Hypertension

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Completed

A Study to Investigate the Effects of Heated Humidification During Non-Invasive Ventilation

Chronic Obstructive Pulmonary Disease | Obesity Hypoventilation Syndrome | Neuromuscular Disease | Chronic Respiratory Hypercapnic Failure

United Kingdom
Michelle Ramsay
Royal Brompton & Harefield NHS Foundation Trust

Completed

Patient -Ventilator Interaction in Chronic Respiratory Failure

Chronic Obstructive Pulmonary Disease | Obesity Hypoventilation Syndrome | Neuromuscular Disease | Chronic Hypercapnic Respiratory Failure

United Kingdom
GlaxoSmithKline

Completed

A Clinical Study Assessing Critical Errors, Training/Teaching Time, and Preference Attributes of the ELLIPTA® Dry Powder Inhaler, in Comparison to Combinations of Dry Powder Inhalers Used to Provide Triple Therapy, in Patients With Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

United Kingdom, Netherlands
Imperial College London

Completed

Osteoprotegerin (OPG) in Induced Chronic Obstructive Pulmonary Disease (COPD) Sputum

Pulmonary Disease, Chronic Obstructive

United Kingdom
Philips Healthcare

Completed

Validation of Medication Non-adherence Model (UK)

Diabetes Mellitus | Chronic Obstructive Pulmonary Disease | Chronic Illness | Primary Care | Medication Management at Home

United Kingdom
University of Nottingham
Nottingham University Hospitals NHS Trust

Recruiting

Functional and Structural Lung Imaging in Chronic Obstructive Pulmonary Disease (FASTCOPD)

Chronic Obstructive Pulmonary Disease | Alpha 1-Antitrypsin Deficiency

United Kingdom
CSA Medical, Inc.

Completed

Safety and Feasibility Study of Rejuvenair™ for Treating Chronic Bronchitis Patients (Feasibility)

Bronchitis, Chronic | Cryotherapy Effect

Netherlands, Canada, United Kingdom
AstraZeneca

Completed

14729-D9831C00002- 1 Month Biopsy Study (Biopsy)

Chronic Obstructive Pulmonary Disease

United Kingdom, Germany, Netherlands
National Health Service, United Kingdom

Unknown

ToAST:Investigating the Effect of Bronchial Thermoplasty on Cough in Patients With Severe Asthma (ToAST)

Asthma Chronic, Cough

United Kingdom
Verona Pharma plc

Completed

SAD/MAD Study of a New Formulation of Nebulised RPL554 in Healthy Subjects and COPD Subjects

Chronic Obstructive Pulmonary Disorder | Inflammatory Disorder of the Respiratory Tract

United Kingdom
University of Lincoln
University of Kent; NHS Lincolnshire West Clinical Commissioning Group; NHS South...

Completed

Influenza Vaccination and COPD Phenotypes

Pulmonary Disease, Chronic Obstructive

United Kingdom
University of Nottingham
Imperial College London; University of Leeds; Vanderbilt University Medical Center and other collaborators

Recruiting

Understanding Gut Symptoms in People With Cystic Fibrosis (GRAMPUS-CF SRC)

Cystic Fibrosis | Gastrointestinal Dysfunction

United Kingdom
Almirall, S.A.
Forest Laboratories

Completed

Preference, Satisfaction and Ease of Use of Genuair® (Pressair™) and Breezhaler® (Neohaler™) Inhalers in Patients With COPD

Chronic Obstructive Pulmonary Disease (COPD)

Germany, Spain, United Kingdom
University of Winchester
University of Gloucestershire

Recruiting

Uninterrupted and Interrupted Sitting in Long COVID-19

COVID-19

United Kingdom
Joseph C. Wu
California Institute for Regenerative Medicine (CIRM)

Recruiting

Human Embryonic Stem Cell-Derived Cardiomyocyte Therapy for Chronic Ischemic Left Ventricular Dysfunction (HECTOR)

Chronic Ischemic Left Ventricular Dysfunction

United States
Kingston University
University College London Hospitals; St. George's Hospital, London

Completed

Toward Self-management in ILD

Idiopathic Pulmonary Fibrosis | Interstitial Lung Disease | Chronic Hypersensitivity Pneumonitis | Connective Tissue Related ILD | Fibrotic Lung Disease

United Kingdom
Bournemouth University

Completed

Feasibility of Personalised Health Behaviour Coaching to Support Symptoms and Activities of Daily Living in Those With Long COVID-19.

Long COVID

United Kingdom
University of Leicester
University Hospitals, Leicester

Completed

Right Heart Dysfunction and Pulmonary Hypertension Evaluation in Airway Disease Using Cardiac Magnetic Resonance (RiPAIR)

Pulmonary Disease, Chronic Obstructive | Asthma

United Kingdom
Spiration, Inc.

Completed

European Multi-center Post Market Study of the IBV Valve System (IBV)

Chronic Obstructive Pulmonary Disease

Spain, Germany, Italy, Austria, Belgium, United Kingdom

Clinical Trials on Chronic Lung Allograft Dysfunction (CLAD) in United Kingdom

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