Clinical Trials on Chronic Obstructive Pulmonary Disease in United States

Total 17054 results

Mrs Hanoof Aljohani
University Hospitals, Leicester

Recruiting

Home-based Body Weight Exercise With Blood Flow Restriction (BFR): Feasibility of a Novel Rehabilitation Intervention in COPD Patients (HomeBFR-COPD) (HomeBFR-COPD)

Chronic Obstructive Pulmonary Disease

United Kingdom
AstraZeneca

Completed

Long-term Efficacy and Safety of Aclidinium Bromide/Formoterol Fumarate Fixed-Dose Combination

Chronic Obstructive Pulmonary Disease (COPD)

Austria, Belgium, Bulgaria, Croatia, Czech Republic, Denmark, Finland, France, Germany, Hungary, Italy, Korea, Republic of, Netherlands, Poland, Romania, Russian Federation, Slovakia, South Africa, Spain, Sweden, Ukraine, United Kingdom
AstraZeneca
MedImmune LLC

Completed

Benralizumab Efficacy in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With Exacerbation History (GALATHEA)

Moderate to Very Severe Chronic Obstructive Pulmonary Disease

United States, Canada, Germany, Italy, Netherlands, Spain, United Kingdom, Poland, Japan, Austria, Korea, Republic of, Russian Federation, South Africa, Czechia, Hungary, Romania, Switzerland
Teesside University

Recruiting

Understanding Balance Impairment in COPD

Chronic Obstructive Pulmonary Disease | Healthy Volunteers

United Kingdom
Sunovion

Completed

Study of Arformoterol Tartrate Inhalation Solution and Racemic Formoterol in Subjects With Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD)

COPD

United States
AstraZeneca

Recruiting

A Study to Investigate the Effect on Lung Function of an Approved COPD Treatment (BGF, With HFA Propellant) Compared to BGF Formulated With a New Propellant (HFO) in Participants 40 to 80 Years of Age With COPD

COPD (Chronic Obstructive Pulmonary Disease)

United States, Turkey, Vietnam, Malaysia, Philippines, Thailand, Hungary, Mexico, Korea, Republic of, Argentina, Canada, India, Bulgaria, Poland
Medicines Evaluation Unit Ltd
Chiesi UK

Completed

A Study Comparing the Effects of Trimbow to Fostair in COPD (TRIFLOW)

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
Novartis Pharmaceuticals

Completed

NVA237 BID Versus Placebo Twelve-week Efficacy Study

Chronic Obstructive Pulmonary Disease

United States
Novartis

Completed

Comparison of Efficacy of Indacaterol Versus Placebo Over 12 Weeks

Chronic Obstructive Pulmonary Disease

United States
Boehringer Ingelheim

Completed

A Study in the US Based on Pharmacy and Medical Claims That Compares How Well Stiolto® and Trelegy® Work in People With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

United States
Patrick Murphy
ResMed; ResMed Foundation; Guy's & St Thomas' Charity; Respironics International

Completed

Home Mechanical Ventilation vs Home Oxygen Therapy in COPD

Chronic Obstructive Pulmonary Disease

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Fibre Specific Signalling in the Locomotor Myopathy of Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United Kingdom
University of California, San Francisco
National Institute of Nursing Research (NINR)

Completed

Dyspnea Self-Management: Internet or Face-to-Face

Chronic Obstructive Pulmonary Disease (COPD)

United States
University of Leicester
Aparito Ltd.

Not yet recruiting

Role of Inhaler Adherence and Blood Eosinophil Count in Exacerbations of COPD (INCLINE)

Chronic Obstructive Pulmonary Disease | Adherence, Treatment

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Novartis

Completed

SILO2 (Signal Intensity Lung washOut) (SILO2)

Chronic Obstructive Pulmonary Disease

United Kingdom
Baylor College of Medicine
M.D. Anderson Cancer Center

Completed

Effect of Curcumin on Lung Inflammation

Chronic Obstructive Pulmonary Disease

United States
Chiesi Farmaceutici S.p.A.

Completed

Efficacy and Safety of Glycopyrrolate Bromide of COPD Patients (Trigon)

Chronic Obstructive Pulmonary Disease

Bulgaria, Germany, Poland, United Kingdom
Imperial College London

Completed

Macrophage Phagocytosis in COPD

Chronic Obstructive Pulmonary Disease | Emphysema | Chronic Bronchitis

United Kingdom
University of Iowa
National Institute of Mental Health (NIMH)

Completed

Combined Illness Management and Psychotherapy in Treating Depressed Elders (COPE)

Depression | Heart Failure | Chronic Obstructive Pulmonary Disease

United States
The University of Texas Health Science Center,...

Completed

Effects of Marijuana Used on Lung Function in Persons With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United States
Novartis Pharmaceuticals

Completed

Efficacy and Safety Study of QVA149 in COPD Patients

Chronic Obstructive Pulmonary Disease

United States
Dey

Completed

Study in Subjects Greater Than 40 Years of Age With COPD

Chronic Obstructive Pulmonary Disease

United States
BioMarck Pharmaceuticals, Ltd.
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effectiveness and Safety of BIO-11006 Inhalation Solution to Treat the Overproduction of Mucus and Inflammation in COPD (BREATH-1)

Chronic Obstructive Pulmonary Disease | COPD

United States
Sanofi
Regeneron Pharmaceuticals

Recruiting

Mechanistic Study of the Effect of Itepekimab on Airway Inflammation in Patients With COPD (AERIFY-3)

Chronic Obstructive Pulmonary Disease

United States, Netherlands, Belgium, Denmark, Germany, United Kingdom, Brazil
Sociedad Española de Neumología y Cirugía Torácica
European Commission; SAVANA

Unknown

Chart Review of Patients With COPD, Using Electronic Medical Records and Artificial Intelligence (BigCOPData)

Chronic Obstructive Pulmonary Disease

Spain, Austria, Switzerland, United Kingdom
AstraZeneca
Parexel

Completed

Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of AZD8871 in Healthy Subjects

Chronic Obstructive Pulmonary Disease

United Kingdom
AstraZeneca

Recruiting

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease (THARROS)

COPD (Chronic Obstructive Pulmonary Disease)

France, Denmark, Italy, Spain, United States, Canada, Argentina, Japan, Colombia, Germany, Peru, Brazil, China, India, Thailand, Austria, Serbia, Malaysia, Philippines, Poland, Taiwan, Greece, Norway, Sweden, Mexico, Romania, Korea, Republic... and more
University of Southern California
Patient-Centered Outcomes Research Institute

Terminated

Expanding Access to Home-Based Palliative Care

Cancer | Chronic Obstructive Pulmonary Disease | Congestive Heart Failure

United States
AstraZeneca

Completed

AMPLIFY - D6571C00001 Duaklir USA Phase III Study

Chronic Obstructive Pulmonary Disease

United States, Germany, Poland, Israel, Bulgaria, Czechia, Hungary, Spain, Ukraine, United Kingdom
Dey

Completed

A Dose-Finding Study Evaluating Safety and Efficacy in Patients With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United States
Sunovion

Completed

A Pivotal Study of the Safety and Effectiveness of Arformoterol in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

COPD

United States
Sunovion Respiratory Development Inc.

Completed

A Study of the Efficacy and Safety of EP-101 ( (SUN101) in Subjects With Moderate to Severe Chronic Obstructive Pulmonary Disease (GOLDEN-2)

COPD

United States
Chiesi Farmaceutici S.p.A.

Completed

PK of BDP/FF/GB Single-inhaler Triple Therapy in Japanese vs. Caucasians

Chronic Obstructive Pulmonary Disease | Asthma

United Kingdom
University of California, San Diego

Terminated

Impact of Non-invasive Ventilation in Hypercapnic COPD

Chronic Obstructive Pulmonary Disease | Copd | Chronic Respiratory Failure | Hypoventilation | Hypercapnia

United States
Chiesi Farmaceutici S.p.A.

Completed

A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Dose in Healthy Volunteers, Repeat Doses in Asthmatic Patients and of Single Dose in COPD Patients of CHF6366

Chronic Obstructive Pulmonary Disease | Asthma

United Kingdom
University of Dundee
AstraZeneca; NHS Tayside

Completed

Microbiome Use to Stratify Use of Inhaled Corticosteroids: MUSIC Trial (MUSIC)

Chronic Obstructive Pulmonary Disease

United Kingdom
University of Lincoln
National Health Service, United Kingdom

Completed

Changes in Inflammatory Markers During Pulmonary Rehabilitation Based on Exacerbation States in COPD (CIMPRES-COPD)

Chronic Obstructive Pulmonary Disease

United Kingdom
University of Chicago
Hill-Rom

Completed

Chest Wall Oscillation for Asthma and COPD Exacerbations Trial (COAT)

Asthma | Chronic Obstructive Pulmonary Disease (COPD) | Undifferentiated Asthma/COPD

United States
Hoffmann-La Roche

Completed

A Study to Evaluate Safety and Efficacy of Lebrikizumab in Participants With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United States, Canada, Bulgaria, Hungary, Russian Federation, Denmark, Argentina, Mexico, Poland
Novartis

Completed

A Study to Assess the Safety, Tolerability and Efficacy of NVA237 Versus Placebo (GLOW 1)

Chronic Obstructive Pulmonary Disease

Russian Federation, Singapore, United States, Canada, Korea, Republic of, Japan, Spain, Turkey, Romania, Australia, Netherlands
Valley Medical Research

Completed

The Effect on Depressive Symptoms in ECF Residents With COPD (DISK-02)

Depression | Chronic Obstructive Pulmonary Disease

United States
AstraZeneca

Completed

A Phase II, Randomized, Double-blind, Placebo-controlled Study to Assess MEDI3506 in Participants With COPD and Chronic Bronchitis (FRONTIER-4)

Chronic Obstructive Pulmonary Disease (COPD) | Chronic Bronchitis

United States, Canada, Denmark, Spain, United Kingdom, Taiwan, New Zealand, Australia, Germany, Israel, South Africa, Czechia, Hungary, Poland, Netherlands
AstraZeneca

Completed

Trial to Assess the Anti-inflammatory Effects of Roflumilast in Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease | COPD

Poland, United Kingdom, Germany, Sweden, Denmark
University of Florida
Takeda

Terminated

COPD Patients Diagnosed With GERD,COPD Exacerbations After Treatment With High Dose PPI (GERD/COPD)

Chronic Obstructive Pulmonary Disease | Gastroesophageal Reflux

United States
Sunovion Respiratory Development Inc.

Completed

Efficacy and Safety Trial of 12 Weeks of Treatment With Nebulized SUN-101 in Patients With COPD (GOLDEN-4) (GOLDEN-4)

Chronic Obstructive Pulmonary Disease | COPD

United States
Mundipharma Research Limited

Completed

A Study to Show That Flutiform is Well Tolerated and Effective in the Treatment of COPD

Chronic Obstructive Pulmonary Disease

Ukraine, United Kingdom, Spain, Bulgaria, South Africa, Russian Federation, Germany, Hungary, Lithuania, Slovakia, Macedonia, The Former Yugoslav Republic of, Latvia, Romania, Korea, Republic of, Poland
Bridgeport Hospital

Unknown

Ventilator Settings and Comfort

Obesity | Chronic Obstructive Pulmonary Disease

United States
Northumbria Healthcare NHS Foundation Trust
GlaxoSmithKline; Newcastle University; Chiesi UK

Recruiting

Eosinopenia in Severe COPD Exacerbation (A-TREC)

Chronic Obstructive Pulmonary Disease

United Kingdom
Hywel Dda Health Board
Swansea University

Completed

sTep dOWn Inhalers in the reAl woRlD (TOWARD)

Chronic Obstructive Pulmonary Disease

United Kingdom
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Different Doses of Indacaterol in Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United States

Clinical Trials on Chronic Obstructive Pulmonary Disease in United States

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