Clinical Trials on Chronic Limb-threatening Ischemia

Total 781 results

Andalusian Initiative for Advanced Therapies -...
Iniciativa Andaluza en Terapias Avanzadas

Terminated

Clinical Trial I/II Opened, Randomized and Controlled for the Study of the Use of Stem Cells Therapy in Insulinized Diabetic Patients Type 2 With Critical Ischemia in Lower Limbs (CLI): Study of the Needs of Insulin

Critical Limb Ischemia (CLI)

Spain
Medtronic Endovascular

Completed

Study of IN.PACT Amphirion™ Drug Eluting Balloon vs. Standard PTA for the Treatment of Below the Knee Critical Limb Ischemia (INPACT-DEEP)

Critical Lower Limb Ischemia

Germany, Belgium, Netherlands, Switzerland, Austria, Italy
Assiut University

Unknown

Combined Management in ALI ( Image Guided Thrombectomy With Open Transfemoral Access )

Limb Ischemia
Pluristem Ltd.

Available

Expanded Access Treatment of Subjects With Critical Limb Ischemia (CLI) With Minor Tissue Loss Who Are Unsuitable for Revascularization

Critical Limb Ischemia (CLI)

United States
WideTrial, Inc.

Available

Expanded Access for Treatment Use of PLX-PAD in Critical Limb Ischemia (CLI)

Critical Limb Ischemia (CLI)
Cesca Therapeutics, Inc.

Unknown

Critical Limb Ischemia Rapid Delivery by SurgWerks-CLI Kit and VXP System (CLIRST III)

Critical Limb Ischemia (CLI)
North Karelia Central Hospital

Completed

Bacterial Growth in Vascular Surgery Wounds

Aneurysm | Lower Limb Ischaemia

Finland
Xuanwu Hospital, Beijing

Recruiting

Excimer Laser Combined With DCB Compared With Angioplasty Alone in the Treatment of Infrapopliteal Lesions.

Critical Limb Ischemia | Infrapopliteal Lesions

China
National University of Malaysia
Cytopeutics Sdn. Bhd.

Unknown

Intramuscular Mononuclear Cells and Mesenchymal Stem Cells Transplantation to Treat Chronic Critical Limb Ischemia

Critical Limb Ischemia

Malaysia
Sohag University

Not yet recruiting

Endovascular Management of Combined Common Femoral and Superficial Femoral Arteries Lesions

Lower Limb Ischemia
Andalusian Initiative for Advanced Therapies -...
Iniciativa Andaluza en Terapias Avanzadas

Completed

Application of Cell Regeneration Therapy With Mesenchymal Stem Cells From Adipose Tissue in Critical Chronic Ischemic Syndrome of Lower Limbs (CLI) in Nondiabetic Patients.

Critical Limb Ischemia

Spain
University of Chicago

Withdrawn

Use Art-assist and Neupogen to Treat Chronic Limb Ischemia

Lower Limb Ischemia

United States
Assiut University

Recruiting

The Role of Pharmaco-mechanical Thrombectomy in Management of Acute Lower Extremity Arterial Ischemia

Acute Limb Ischemia

Egypt
Ospedale San Donato

Unknown

Comparison of Sirolimus vs Paclitaxel Drug Eluting Balloon for Below-the-knee Angioplasty in Critical Limb Ischemia (DebateBTKDuell)

Drug Effect | Critical Limb Ischemia

Italy
Mansoura University

Completed

A Trial Comparing Routine Versus Selective Use of Completion Angiography After Surgical Thromboembolectomy in the Treatment of Acute Lower Limb Ischemia and Their Impacts on Limb Salvage Rates

Acute Limb Ischemia

Egypt
Lancashire Care NHS Foundation Trust
St. Franziskus Hospital

Unknown

Acute Limb Ischaemia (ALI) Management With 'Indigo' Mechanical Aspiration System

Lower Limb Ischemia

United Kingdom
Mast Therapeutics, Inc.

Terminated

Evaluation of MST-188 in Acute Lower Limb Ischemia

Acute Limb Ischemia

United States
Assiut University

Not yet recruiting

Outcomes of Endovascular Revascularization in CLTI in Patients Associated With Heel Ulcers

Lower Limb Ischemia Critical
Stanford University
National Heart, Lung, and Blood Institute (NHLBI); Medtronic Endovascular

Enrolling by invitation

The Use of FlowMet-R Technology to Predict Wound Healing in CLI Patients in a Wound Care Center Setting

Critical Limb Ischemia

United States
Andalusian Initiative for Advanced Therapies -...
Iniciativa Andaluza en Terapias Avanzadas

Completed

Intra-arterial Infusion of Autologous Bone Marrow Mononuclear Cells in Non-diabetic Patients With Critical Limb Ischemia (CLI).

Critical Limb Ischemia (CLI)

Spain
Kuopio University Hospital
Turku University Hospital; Helsinki University Central Hospital; Oulu University... and other collaborators

Recruiting

Paclitaxel Eluting Stent in Long SFA Obstruction: A Prospective, Randomized Comparison With Bypass Surgery (finnptx)

Claudication | Chronic Lower Limb Ischemia | Critical Ischemia | Peripheral Athero Obstructive Disease

Finland
Pedra Technology, PTE LTD

Completed

Improving Radiological Outcomes in Arterial Disease - A Pilot Evaluation of the Pedra Tissue Perfusion Monitoring System (IROAD)

Peripheral Arterial Disease | Chronic Limb Ischemia

United Kingdom
University Hospital, Strasbourg, France

Completed

Protective Effects of L-arginine During Reperfusion by Femoropopliteal Bypass for Lower Limb Ischemic Syndrome in Humans

Skeletal Muscle Ischemia | Severe Lower Limb Ischemia | Mitochondrial Dysfunction

France
Centre Hospitalier Universitaire de Nīmes

Not yet recruiting

Can the BeatMove Device Help Patients With Obliterative Arterial Disease of the Lower Limbs? (LEGS GO)

Lower Limb Ischemia | Atheromatous | Artery Disease
Southwest Regional Wound Care Center

Completed

A Retrospective Analysis of Patients With Full Thickness Wounds in Limbs With Critical Ischemia

Critical Limb Ischemia

United States
Grupo Rehabilitacion en Salud
Instituto Colombiano para el Desarrollo de la Ciencia y la Tecnología (COLCIENCIAS) and other collaborators

Completed

TeleEducation for Implementing a Clinical Practice Guideline For Amputees (TEFICA)

Diabetes Mellitus | Lower Limb Amputation Below Knee (Injury) | Lower Limb Amputation Above Knee (Injury) | Rehabilitation | Prosthesis User | Lower Limb Ischemia | Lower Limb Amputation Knee | Clinical Practice Guidelines

Colombia
Meshalkin Research Institute of Pathology of Circulation

Recruiting

Efficacy and Safety Comparison of the Open and Endovascular Surgical Methods for the Treatment of Long Atherosclerotic Lesions of the Femoral-popliteal Segment Below the Knee, TASC D in Patients With Critical Limb Ischemia

Superficial Femoral Artery Occlusion | Popliteal Artery Occlusion | Atherosclerotic Ischemic Disease | Critical Limb Ischemia

Russian Federation
Science Valley Research Institute
Wyeth is now a wholly owned subsidiary of Pfizer

Recruiting

Efficacy and Safety of Apixaban in Reducing Restenosis and Limb Loss in PAD Patients. (AGRIPPA)

Critical Limb Ischemia

Brazil
TotipotentSC Scientific Product Pvt. Ltd.
Thermogenesis Corp.

Completed

Safety and Efficacy of Autologous Bone Marrow Mononuclear Cells in Patients With Severe Critical Limb Ischemia

Critical Limb Ischemia

India
University Hospital Erlangen

Completed

Open Versus Endovascular Revascularization in Patients With End-stage Renal Disease (OERESRD)

End-stage Renal Disease | Critical Limb Ischemia

Germany
Hull University Teaching Hospitals NHS Trust

Completed

Peripheral Vascular Disease and Nerve Stimulation (CCLINS)

Varicose Veins | Claudication | Ulcers | Critical Limb Ischaemia | Post Angioplasty

United Kingdom
Centre Hospitalier Universitaire de Nice

Recruiting

OUTCOME OF PATIENTS ADMITTED WITH ACUTE LOWER EXTREMITY ISCHEMIA (DEVENIR-IAM)

Acute Ischemia of Lower Limb

France
University of Illinois at Chicago

Completed

Proteomics and Stem Cell Therapy as a New Vascularization Strategy

Critical Limb Ischemia

United States
Yonsei University

Unknown

Comparison of Cilostazol-based Triple Antiplatelet Therapy Versus Dual Antiplatelet Therapy for Outcomes of below-the Knee Endovascular Intervention in Patients With Critical Limb Ischemia (TAP CLI Study)

Critical Limb Ischemia

Korea, Republic of
Azienda Ospedaliera Universitaria Senese

Unknown

The Indigo System in Acute Lower Limb Malperfusion (INDIAN)

Acute Ischemia of Lower Limb

Italy
Juventas Therapeutics, Inc.

Completed

Study to Evaluate the Safety and Efficacy of JVS-100 Administered to Adults With Critical Limb Ischemia

Critical Limb Ischemia

United States, India
Southern Arizona Vascular Institute
Southern Illinois University

Unknown

UT-15C SR in the Treatment of Critical Limb Ischemia

Critical Limb Ischemia

United States
Kafrelsheikh University

Active, not recruiting

Outcomes of Straight-line Flow Versus Angiosome-targeted Angioplasty in Treatment of Critical Lower Limb Ischemia

Critical Lower Limb Ischemia | Angioplasty

Egypt
Ochsner Health System
United Therapeutics

Completed

Safety Study of UT-15C SR (Oral Treprostinil) in Patients Undergoing a Lower Limb Endovascular Procedure

Critical Limb Ischemia

United States
University Hospital, Angers

Completed

New Oxymetry Indices in Critical Limb Ischemia (NOVICE)

Critical Limb Ischemia

France
Tissue Genesis

Active, not recruiting

Feasibility Study of the TGI Adipose-derived Stromal Cell (ASC)-Coated ePTFE Vascular Graft (TGI-PVG-IDE)

Lower Limb Ischemia

United States
Vericel Corporation

Completed

An Efficacy and Safety Study of Ixmyelocel-T in Patients With Critical Limb Ischemia (CLI) (REVIVE)

Critical Limb Ischemia

United States
Cook Research Incorporated

Terminated

HemaTrate™ in the Treatment of Critical Limb Ischemia

Ischemia | Critical Limb Ischemia

United Kingdom
Helixmith Co., Ltd.

Completed

Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia

Critical Limb Ischemia

United States, Korea, Republic of
Helixmith Co., Ltd.

Completed

Safety Study of Gene Therapy in Treating Lower Leg Ischemia

Critical Limb Ischemia

United States
The Cleveland Clinic

Withdrawn

Correlation Between FlowMet™ and Other Gold Standard Assessments in the Management of Critical Limb Ischemia (CLI)

Critical Limb Ischemia

United States
Richard Burt, MD

Terminated

Efficacy and Safety of Umbilical Cord Blood Injection for Critical Limb Ischemia

Critical Limb Ischemia

United States
Clinical Centre of Serbia
University of California, Los Angeles

Unknown

Distal Venous Arterialisation of Ischemic Limb

Critical Limb Ischemia

Serbia
Medical University of Vienna

Unknown

Viennese Registry on Patients With Chronic Critical Limb Ischemia

Chronic (> 2 Weeks) Critical Ischemia With Skin Defect in Lower Limbs

Austria
Micro Medical Solution, Inc.

Recruiting

An All-Comers Observational Study of the MicroStent™ Peripheral Vascular Stent System in Subjects With Peripheral Arterial Disease (HEAL)

Peripheral Arterial Disease | Peripheral Artery Disease | Critical Limb Ischemia | Critical Lower Limb Ischemia

Austria, Belgium, Germany, Italy, Netherlands

Clinical Trials on Chronic Limb-threatening Ischemia

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Hungary

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations