Clinical Trials on Circadian Dysregulation

Total 301 results

Hospital Italiano de Buenos Aires

Unknown

Well-Being in Medical Residents in the HIBA

Depression | Anxiety | Cognition Disorders | Shift-Work Sleep Disorder
Shalvata Mental Health Center
University of Haifa

Completed

Correlating Real and Virtual World Behavioral Fluctuations in Adolescence

Depression | Anxiety | Oppositional Defiant Disorder | Disruptive Mood Dysregulation Disorder | Conduct | Attention-Deficit and Hyperactivity Disorder

Israel
Neurim Pharmaceuticals Ltd.

Completed

Efficacy and Safety of Circadin for Non-24 Hour Sleep-Wake Disorder in Totally Blind Subjects

Blindness | Non-24 Hour Sleep-Wake Disorder

United States
Aarhus University Hospital
University of Aarhus; Danish Cancer Society

Recruiting

The Role of Circadian Rhythms in Cancer-Related Symptoms (CHRONO)

Depression | Quality of Life | Inflammation | Breast Cancer | Fatigue | Stress, Psychological | Cognitive Impairment | Sleep | Circadian Rhythm Disorders | Cancer-Related Syndrome

Denmark
Haukeland University Hospital
University of Bergen

Recruiting

Sleep in Psychiatric Care (SIP): Treatment for Comorbid Delayed Sleep-Wake Phase Disorder (DSWPD) (SIP)

Sleep Disorder | Psychiatric Disorder | Delayed Sleep-Wake Phase Disorder

Norway
Assaf-Harofeh Medical Center
Hadassah Medical Organization; Western University, Canada

Not yet recruiting

Influence of Circadian Clock on Hormonal, Metabolic, Neurocognitive Markers in Adolescents With and Without Diabetes

ADHD | Memory Impairment | T1DM | Sleep Disorders, Circadian Rhythm
University of California, San Francisco

Terminated

Pilot Trial of Clofarabine Added to Standard Busulfan and Fludarabine for Conditioning Prior to Allogeneic Hematopoietic Cell Transplantation

Myeloid Malignancy | Metabolic Disease | Bone Marrow Failure Syndrome | Transfusion-dependent Red Blood Cell (RBC) Defect | Congenital Immunodeficiency | Severe Immune Dysregulation

United States
University Hospital, Strasbourg, France

Recruiting

Light Therapy for Chronic Insomnia in General Practice (Insolux)

Sleep Disorder | Insomnia Chronic | Circadian Rhythm Disorders

France
Universidad de Murcia

Unknown

The Efficacy of Melatonin in the Burning Mouth Syndrome (BMS)

Sleep Disorders, Circadian Rhythm

Spain
Vanda Pharmaceuticals

Completed

Evaluating the Effects of Tasimelteon vs. Placebo on Jet Lag Type Insomnia

Jet Lag Type Insomnia

United States
Vanda Pharmaceuticals

Completed

Tasimelteon for the Treatment of Non-24-hour Sleep-Wake Disorder (N24HSWD) in Blind Individuals With no Light Perception

Non-24-Hour Sleep-Wake Disorder

United States
Hospital of South West Jutland
Odense University Hospital; Rigshospitalet, Denmark; University of Southern Denmark and other collaborators

Recruiting

Sleep, Obesity and Mental Disease - Biological Markers for the Evaluation of Circadian Rhythmicity (SOMBER)

Obesity | Schizophrenia | Bipolar Disorder | Circadian Rhythm Disorders

Denmark
University of Pittsburgh
National Institute on Aging (NIA)

Recruiting

Self-Care for Dementia Caregivers (Care2)

Sleep | Dementia | Alzheimer Disease | Aging | Mental Disorder | Prodromal Symptoms | Physical Inactivity | Circadian Rhythm Disorders | Eating, Healthy

United States
Oregon Health and Science University
University of Washington; National Institute for Occupational Safety and Health... and other collaborators

Unknown

Tech4Rest Trial With Team Truck Drivers (Tech4Rest)

Fatigue | Sleep | Sleep Disturbance | Health Behavior | Health Knowledge, Attitudes, Practice | Vibration; Exposure | Sleep Disorder, Shift Work

United States
Vanda Pharmaceuticals

Completed

Withdrawal Study to Demonstrate the Maintenance Effect in the Treatment of Non-24-Hour Sleep-Wake Disorder

Non-24-Hour Sleep-Wake Disorder

United States
Duke University
National Institute of Mental Health (NIMH)

Recruiting

Neurostimulation Versus Therapy for Problems With Emotions

Mood Disorders | Obsessive-Compulsive Disorder | Anxiety Disorders | OCD | Borderline Personality Disorder | Stress Disorder | Emotional Distress | Emotion Regulation | Eating Disorders | Emotion Dysregulation | Emotional Dysfunction | Emotional Impulsivity | Emotional Instability | Impulse Control Disorder | Emotional...

United States
Children's Hospital Medical Center, Cincinnati

Completed

Enhanced Support for Behavioral Barriers to Learning: An Evaluation of the SCHOOL STARS Program

Attention Deficit Hyperactivity Disorder | Disruptive Mood Dysregulation Disorder | Oppositional Defiant Disorder in Children | Disruptive Behavior Disorder, Childhood Onset

United States
Vanda Pharmaceuticals

Completed

Efficacy and Safety of Tasimelteon Compared With Placebo in Totally Blind Subjects With Non-24-Hour Sleep-Wake Disorder

Non-24-Hour Sleep-Wake Disorder

United States, Germany
University of Chicago

Completed

Shift Work and Risk of Cardio-vascular Disease

Shift-Work Sleep Disorder
Hospices Civils de Lyon

Not yet recruiting

Circadian Rhythm Disorders in Children With Cystic Fibrosis Under CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) Modulators (CHRONO-MUCO)

Cystic Fibrosis

France
Norwegian Institute of Public Health
University of Bergen

Recruiting

Health Promoting Work Schedules: The Effect of Abolishing Quick Returns (HeWoS)

Fatigue | Insomnia | Health, Subjective | Psychological Distress | Shift-Work Sleep Disorder | Sick Leave | Work Accident | Turnover Intention | Work-family Spillover

Norway
Vanda Pharmaceuticals

Completed

Evaluating the Effects of Tasimelteon vs Placebo on Sleep Disturbances in SMS

Smith-Magenis Syndrome | Circadian

United States
Kyoto University

Completed

Circadian Variations of Prostaglandin in Sleep Apnea

Sleep Apnea | Continuous Positive Airway Pressure | Prostaglandins | Circadian Variations

Japan
Reykjavik University
The Icelandic Research Fund

Recruiting

The Effects of Light Therapy to Treat Cancer-related Side Effects

Depression | Breast Cancer | Fatigue | Cognitive Impairment | Inflammatory Response | Sleep Disturbance | Circadian Rhythms

Iceland
Cephalon

Completed

Safety/Efficacy Study With Armodafinil (CEP-10953) in Treatment of Excessive Sleepiness Associated With Chronic SWSD

Excessive Sleepiness | Shift Work Sleep Disorder
Brigham and Women's Hospital
University of Pennsylvania; National Heart, Lung, and Blood Institute (NHLBI); Beth Israel Deaconess Medical Center and other collaborators

Not yet recruiting

Adult Sleep Health in the Rural Appalachia and Mississippi Delta Region and Its Relationships With Cardiometabolic Health Disparities.

Fatigue | Insomnia | Sleep Apnea | Sleep Deprivation | Sleep Disorders, Circadian Rhythm | Sleepiness, Excessive Daytime

United States
Neurological Institute of Athens
King's College London; Uppsala University; Rabin Medical Center; University of... and other collaborators

Recruiting

Multidisciplinary Expert System for the Assessment & Management of Complex Brain Disorders (MES-CoBraD)

Epilepsy | Healthy | Sleep Disorder | Dementia | Alzheimer Disease | Circadian Rhythm Disorders

Israel, United Kingdom, Greece, Spain
Aretaieion University Hospital

Recruiting

General Versus Regional Anesthesia and Postoperative Sleep Quality (AnesthSleep)

Sleep Disorder | Sleep Initiation and Maintenance Disorders | Sleep | Sleep Disturbance | Surgery | Anesthesia | Sleep Fragmentation | Sleep Disorders, Circadian Rhythm

Greece
Brian Gehlbach
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Improving the Sleep and Circadian Rhythms of Mechanically Ventilated Patients

Critical Illness | Respiratory Failure | Sleep Deprivation | Sleep Disorders, Circadian Rhythm

United States
Second Affiliated Hospital of Soochow University

Recruiting

Light Therapy in Parkinson's Disease

Parkinson Disease | Sleep Disorder | Circadian Rhythm Disorders

China
Rigshospitalet, Denmark
Glostrup University Hospital, Copenhagen

Completed

Sleep Wake and Melatonin Pattern in Craniopharyngioma

Craniopharyngioma | Sleep Disorders, Circadian Rhythm
Finnish Institute of Occupational Health
City of Helsinki; Finnish Work Environment Fund; NordForsk; City of Turku, Occupational... and other collaborators

Unknown

Cognitive Behavioral Therapy for Insomnia Among Different Types of Shift Workers (CBT-INSOMNIA)

Chronic Insomnia | Sleep Disorders, Circadian Rhythm | Cognitive Behavioral Therapy | Sleep Disorders, Shift-Work

Finland
Washington University School of Medicine
Patient-Centered Outcomes Research Institute; University of Michigan

Recruiting

Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial (THRIVE)

Depression | Quality of Life | Pain, Postoperative | Surgery | Anesthesia Morbidity | Anesthesia | Sleep Disorders, Circadian Rhythm | Anesthesia Awareness | Anesthesia Complication | Surgery-Complications

United States
Tianjin Medical University Cancer Institute and...

Recruiting

Osimertinib Plus Dalpiciclib in Patients With EGFR-mutant, CDK4/6 Pathway Aberrant, Advanced Non-small Cell Lung Cancer Following Acquired Resistance to Third-generation EGFR TKI: a Phase II Trial

Non-small Cell Lung Cancer | EGFR Activating Mutation | EGFR-TKI Resistant Mutation | Cell Cycle Deregulation

China
Dayzz Live Well Ltd.

Completed

Evaluation of the Reliability and Validity of a Diagnostic Sleep Disorders Questionnaire

Sleep Apnea Syndromes | Insomnia | Circadian Rhythm Disorders | Insufficient Sleep Syndrome

Israel, United States
Brigham and Women's Hospital

Completed

Sleep Disorders Management, Health and Safety in Police

Sleep Apnea, Obstructive | Restless Legs Syndrome | Sleep Initiation and Maintenance Disorders | Sleep Disorders | Sleep Disorders, Circadian Rhythm

United States
Izmir Bakircay University

Recruiting

Ganglion Cell Thickness in Enuresis Nocturna

Circadian Rhythm Disorders | Ganglion | Enuresis, Nocturnal

Turkey
Brigham and Women's Hospital

Completed

Comprehensive Police Fatigue Management Program

Sleep Apnea, Obstructive | Restless Legs Syndrome | Sleep Initiation and Maintenance Disorders | Sleep Disorders | Sleep Disorders, Circadian Rhythm

United States
Federal State Budgetary Institution, V. A. Almazov...

Recruiting

The Role of Circadian Factors in Regulation of Neuroplasticity in Ischemic Stroke (Interventional)

Sleep Disorders, Circadian Rhythm | Ischemic Stroke, Acute

Russian Federation
Second Affiliated Hospital of Soochow University

Unknown

the Efficacy and Safety of Agomelatine in the Patients With Parkinson's Disease

Depression | Parkinson Disease | Sleep Disorders | Circadian Rhythm Disorders
Chinese University of Hong Kong

Recruiting

High-frequency Transcranial Random Noise Stimulation (Hf-tRNS) for Sleep Disturbances in Neurocognitive Disorders Due to Vascular Disease

Cognitive Impairment | Vascular Dementia | Sleep Disorders, Circadian Rhythm

Hong Kong
Cephalon, Inc.

Terminated

The Nuvigil and Provigil Pregnancy Registry

Obstructive Sleep Apnea | Narcolepsy | Shift Work Sleep Disorder

United States
Gynaecologisch Oncologisch Centrum Zuid
Radboud University Medical Center; Maastricht University Medical Center; Erasmus... and other collaborators

Recruiting

Signal TrAnsduction Pathway Activity Analysis in OVarian cancER (STAPOVER)

Recurrent Ovarian Cancer | Therapy-Associated Cancer | Signal Transduction Pathway Deregulation

Netherlands
Cephalon

Completed

Armodafinil (CEP-10953) for Treatment of Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, or Chronic Shift Work Sleep Disorder

Sleep Apnea Syndromes | Sleep Apnea, Obstructive | Narcolepsy | Shift-Work Sleep Disorder

United States, Russian Federation
King's College London
King's College Hospital NHS Trust; Northern Care Alliance NHS Foundation Trust and other collaborators

Not yet recruiting

Clinical Response of Impulsivity After Brain Stimulation in Parkinson's Disease (CRIPS)

Parkinson Disease | Impulsive Behavior | Gambling, Pathological | Hoarding Disorder | Caregiver Burnout | Dopamine Dysregulation Syndrome | Hypersexuality | Impulse Disorders | Eating, Binge | Compulsive Shopping
National Human Genome Research Institute (NHGRI)

Completed

Treatment Strategies for Children With Smith-Magenis Syndrome

Mental Retardation | Sleep Disorders, Circadian Rhythm | Developmental Delay Disorders | Chromosome Deletion | Self Injurious Behavior

United States
Washington University School of Medicine
Patient-Centered Outcomes Research Institute; University of Pennsylvania; University... and other collaborators

Active, not recruiting

THRIVE Feasibility Trial (THRIVE)

Depression | Quality of Life | Pain, Postoperative | Surgery | Anesthesia Morbidity | Surgery--Complications | Anesthesia | Nausea, Postoperative | Sleep Disorders, Circadian Rhythm | Anesthesia Awareness | Anesthesia Complication | Anesthesia Emergence Delirium

United States
Brigham and Women's Hospital
Federal Emergency Management Agency

Completed

Fire Fighter Fatigue Management Program: Operation Healthy Sleep

Insomnia | Obstructive Sleep Apnea | Injuries | Shift-Work Sleep Disorder | Impaired Driving | Restless Leg Syndrome

United States
Brigham and Women's Hospital
Federal Emergency Management Agency

Completed

Fire Fighter Fatigue Management Program: Operation Fight Fatigue

Insomnia | Obstructive Sleep Apnea | Shift-Work Sleep Disorder | Impaired Driving | Restless Leg Syndrome

United States
Cephalon

Completed

Extension Study of the Safety and Efficacy of Armodafinil in the Treatment of Patients With Excessive Sleepiness

Narcolepsy | Excessive Daytime Sleepiness | Chronic Shift Work Sleep Disorder | Obstructive Sleep Apnea/Hypopnea Syndrome

United States, Australia, Canada, France, Puerto Rico, Germany, Russian Federation

Clinical Trials on Circadian Dysregulation

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