Clinical Trials on Cirrose hepática

Total 1501 results

Medical College of Wisconsin

Terminated

Early Cycle Ergometry for Critically-Ill Liver Failure Patients in a Transplant Intensive Care Unit

Liver Failure | ICU Acquired Weakness | Liver Cirrhoses

United States
H. Lundbeck A/S

Completed

Pharmacokinetics Properties of Single Oral Dosing of Lu AE58054 in Subjects With Hepatic Impairment (Mild and Moderate) and in Healthy Subjects

Heptic Impairment

Germany
University Medical Centre Ljubljana
Johns Hopkins University; Medical University of Graz; University of Ljubljana...

Recruiting

Role of MRI in Detection of Minimal Hepatic Encephalopathy

Hepatic Encephalopathy | Liver Cirrhoses

Slovenia
University of California, San Francisco
Johns Hopkins University; Duke University

Completed

Exercise Intervention in Liver Transplant Patients

End Stage Liver Disease | Sarcopenia | Liver Cirrhoses

United States
Dongguan HEC TaiGen Biopharmaceuticals Co., Ltd.
Peking University People's Hospital

Completed

To Evaluate Efficacy and Safety in TG-2349 Combination With DAG181 (± Ribavirin) in HCV Genotype I Infected Patients

Cirrhosis | Chronic Hepatics C Virus (HCV) Genotype 1 | Non-Cirrhotic | Treatment naïve

China
Institute of Liver and Biliary Sciences, India

Recruiting

Risk Factors of Liver Fibrosis Among First Degree Relatives of Patients With NASH Related Cirrhosis (NRC)

Liver Cirrhoses

India
Institute of Liver and Biliary Sciences, India

Completed

Indirect Calorimeter Based Study in Patients With Liver Cirrhosis (METALIC)

Liver Cirrhoses

India
Dr.med. Monica Rusticeanu
University Hospital Inselspital, Berne; University of Bern

Terminated

Alterations in Intestinal Mucosal Barrier Visualized by Confocal Laser Endomicroscopy in Liver Cirrhosis: a Pilot Trial (AMBIC) (AMBIC)

Liver Cirrhoses

Switzerland
Judit Pich

Completed

Simvastatin Plus Rifaximin in Decompensated Cirrhosis (LIVERHOPE)

Cirrhoses, Liver

Spain, Germany, United Kingdom, Italy, Netherlands, France
Institute of Liver and Biliary Sciences, India

Unknown

Propofol for Sedation of Postoperative Electively Ventilated Liver Transplant Recipients.

Liver Cirrhoses

India
Massachusetts General Hospital
Shriners

Recruiting

Developing Viability Index for Machine Perfused Livers

Liver Cirrhoses

United States
Institute of Liver and Biliary Sciences, India

Unknown

To Study the Efficacy and Safety of TIPS (Trans Intrahepatic Portosystemic Shunt) Versus Self Expanding Metallic Stent (SEMS) in the Management of Refractory Variceal Bleed in Cirrhotics.

Liver Cirrhoses

India
Institute of Liver and Biliary Sciences, India

Unknown

Efficacy and Safety of Early TIPS (Transjugular Intrahepatic Portosystemic Shunts) in the Management of Cirrhosis With Recurrent Ascites.

Liver Cirrhoses

India
Abdelrahman Salah Eldin Abodief

Not yet recruiting

Assessing of Physicians' Knowledge About International Guidelines of Albumin Use in Patients With Liver Cirrhosis

Liver Cirrhoses
University Hospital, Bonn

Recruiting

Non-Invasive Characterization of Focal Liver Lesions in Liver Cirrhosis (NICETIES)

Liver Cirrhoses

Germany
Judit Pich

Completed

Efficacy of the Combination of Simvastatin Plus Rifaximin in Patients With Decompensated Cirrhosis to Prevent ACLF Development (2018-001698-25)

Liver Cirrhoses

Belgium, Spain, United Kingdom, Italy, Netherlands, France, Germany
Institute of Liver and Biliary Sciences, India

Unknown

"To Study the Impact of Balloon-occluded Retrograde Transvenous Obliteration (BRTO)/Plug Assisted Retrograde Transvenous Obliteration (PARTO) Mediated Portal Flow Modulation in Reduction of Ammonia and Improvement in Organ Volume and Functionality in Patients of Cirrhosis With LR Shunt

Liver Cirrhoses

India
Instituto Nacional de Ciencias Medicas y Nutricion...

Unknown

Evaluation of Intestinal Permeability in Cirrhotic Patients Before and After Treatment With Non-selective Beta Blocker (Propranolol)

Liver Cirrhoses

Mexico
Seoul National University Hospital

Active, not recruiting

Preoperative Portal and Splanchnic Flow Measurement Using MRI

Liver Cirrhoses

Korea, Republic of
Air Force Military Medical University, China

Recruiting

Early Use of TIPS With Polytetrafluoroethylene(PTFE) Covered Stents in Cirrhotic Patients With Refractory Ascites

Liver Cirrhoses

China
Centre Hospitalier Universitaire de Nīmes

Terminated

Concordance Between Echocardiographic Assessment Performed in the Initial Phase of Decompensated Cirrhosis With Edema and Ascites by an Expert Intensive Care Physician and a Non-expert Gastroenterologist (EchoCirrho)

Liver Cirrhoses

France
Novartis Pharmaceuticals

Completed

Evaluation of Hepatic Function Impairment on the Pharmacokinetics of LEE011

Normal Hepatic Function | Impaired Hepatic Function

United States
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDE225..

Normal Hepatic Function | Impaired Hepatic Function

Belgium, Germany, Israel, Bulgaria, United States
Daegu Catholic University Medical Center

Completed

The Effects of the Anhepatic Phase Extended by Temporary Portocaval Shunt on Anesthetic Sensitivity and Cognitive Function

Liver Cirrhoses
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDK378 Pharmacokinetics

Normal Hepatic Function | Impaired Hepatic Function

United States
GlycoMimetics Incorporated

Completed

A Study to Evaluate the Effect of IV Doses of Rivipansel in Subjects With Moderate Hepatic Impairment and in Healthy Subjects With Normal Hepatic Function

Moderate Hepatic Impairment | Normal Hepatic Function

United States
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Investigate the Effect of Severely Diminished Liver Function on the Metabolism, Safety, and Tolerability of a Single Oral Dose of Enzalutamide in Men

Severe Hepatic Impairment | Normal Hepatic Function

Bulgaria
Pfizer

Completed

Pharmacokinetics Of Orally Administered Fx-1006A In Subjects With Hepatic Dysfunction

Mild Hepatic Dysfunction | Moderate Hepatic Dysfunction

South Africa
Sequana Medical N.V.

Recruiting

International Alfapump Cohort Study (TOPMOST)

Liver Cirrhoses | Malignant Ascites

Germany, Switzerland
Hong Kong Children's Hospital

Recruiting

Ultrasound Measurements of Hepatic Vasculatures and Hepatic Doppler Assessment of Healthy Children

Portal Vein | Hepatic Veins | Hepatic Artery | Liver Circulation

Hong Kong
Pfizer

Recruiting

A Study to Learn About the Study Medicine (Called Lorlatinib) in People With Liver Dysfunction

Healthy Volunteers | Moderate Hepatic Impairment | Severe Hepatic Impairment

United States
Copenhagen University Hospital, Hvidovre
Aarhus University Hospital; Rigshospitalet, Denmark; University of Copenhagen

Terminated

Statins for Prevention of Disease Progression and Hospitalization in Liver Cirrhosis (STATLiver)

Liver Cirrhoses

Denmark
Assistance Publique - Hôpitaux de Paris

Unknown

Patients' Outcome With Severe or Fulminant Hepatic Insufficiency, Hospitalized in the Public Hospitals of Paris (DEVINHEF)

Fulminating Hepatic Failure

France
Eisai Inc.

Completed

A Pharmacokinetic and Safety Study of E7080 in Subjects With Mild (10 mg), Moderate (10 mg), and Severe Hepatic Impairment (5 mg) and Normal Hepatic Function (10 mg)

Hepatic Impairment | Hepatic Function

United States
Vital Therapies, Inc.

Completed

Phase 2 Evaluation of the ELAD System in the Management of Acute Liver Failure

Fulminant Hepatic Failure

United States
Vital Therapies, Inc.

Withdrawn

Safety and Efficacy of the Extracorporeal Liver Assist Device (ELAD®) In Patients With Fulminant Hepatic Failure (FHF) (ELAD)

Fulminant Hepatic Failure

United States
Agios Pharmaceuticals, Inc.

Completed

A Pharmacokinetic Study of Mitapivat in Participants With Moderate Hepatic Impairment Compared to Matched Healthy Control Participants With Normal Hepatic Function

Moderate Hepatic Impairment

United States
Institute of Liver and Biliary Sciences, India

Unknown

The Spectrum and Profile of COVID-19 Infection and Its Impact on Liver.

Liver Cirrhoses

India
Bausch Health Americas, Inc.

Terminated

Steady-State Pharmacokinetics of Rifaximin 550 mg Tablets in Healthy and Hepatically Impaired Subjects

Severe Hepatic Impairment

United States
Janssen Research & Development, LLC

Completed

A Study to Assess the Effects of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine

Hepatic Impairment | Normal Hepatic Function

United States
Cardiox Corporation

Terminated

Liver Function Assessment - Feasibility and Dosing Study

Hepatic Failure
Merck Sharp & Dohme LLC

Completed

Belzutifan (MK-6482) Hepatic Impairment Study (MK-6482-020)

Moderate Hepatic Impairment

United States
EQRx International, Inc.

Completed

An Open-Label, Single-Dose, Parallel-Group Study of the Pharmacokinetics and Safety of EQ143

Severe Hepatic Impairment

United States
Pfizer

Completed

Evaluate Severe Hepatic Impairment on Dacomitinib PK

Severe Hepatic Impairment

United States
Takeda

Completed

Pharmacokinetics, Safety and Tolerability of Vortioxetine in Normal Hepatic Function or Severe Hepatic Impairment

Severe Hepatic Impairment

United States
Institute of Liver and Biliary Sciences, India

Completed

N-Acetyl Cysteine in the Prevention of Contrast Induced Nephropathy in Cirrhosis of Liver-NEPHRO Trial

Liver Cirrhoses

India
Jonel Trebicka

Completed

Role of SWE-change After TIPS in the Prediction of Prognosis After TIPS (TIPS-SWE)

Portal Hypertension | Liver Cirrhoses
University Hospital, Strasbourg, France

Recruiting

Hydrodissection of the Hepatoduodenal Ligament (Duodenal)

Hepatic Lesions

France
Rennes University Hospital

Completed

Pharmacogenetic Study of Tacrolimus in Hepatic Transplant (CYPTAC'H)

Hepatic Transplantation

France
Maastricht University

Completed

Liver Glycogen Dynamics (LGD)

Hepatic Glycogen

Netherlands

3

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