Clinical Trials on Classical Phenylketonuria(PKU)

Total 317 results

Yale University

Withdrawn

A Risk Stratified Sequential Treatment With Rituximab, Brentuximab Vedotin and Bendamustine (RBvB)

Hematopoietic/Lymphoid Cancer | Infectious Mononucleosis | PTLD | Lymphoid Tumor | Plasmacytic Hyperplasia PTLD | Florid Follicular Hyperplasia PTLD | Polymorphic PTLD | Monomorphic PTLD | Classical Hodgkin Lymphoma Type PTLD

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI); University of California, San Francisco; George... and other collaborators

Completed

AIDS and Cancer Specimen Bank (ACSB)

Cancer | Non-Hodgkin's Lymphoma | AIDS | Kaposi's Sarcoma AIDS Related | Kaposi's Sarcoma Classical | HEMATOPOIETIC SYSTEM

United States
Egalet Ltd

Completed

Study to Assess the PK of Ketorolac Tromethamine Intranasal and to Assess the Effects of a Oxymetazoline Hydrochloride on the PK of Ketorolac Tromethamine

Assess Pharmacokinetics of Ketorolac Tromethamine Intranasal and Assess Effects of a Oxymetazoline Hydrochloride on the PK of Ketorolac Tromethamine

United Kingdom
Janssen-Ortho LLC
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

Potential Impact (Benefit) of Preventative Treatment With Topamax on the Effectiveness of Axert in the Acute Treatment of Migraine

Migraine | Common Migraine | Classic Migraine
Ortho-McNeil Neurologics, Inc.

Completed

Evaluation of the Effectiveness of Topiramate in Preventing the Transformation From Episodic Migraine to Chronic Daily Headache.

Migraine | Headache | Common Migraine | Classic Migraine
Fondazione Italiana Linfomi - ETS

Not yet recruiting

Lifestyles Implemented-Survivorship Care Plan In Lymphoma Survivors

Classical Hodgkin Lymphoma | Primary Mediastinal Large B-cell Lymphoma (PMBCL) | Diffuse Large B Cell Lymphoma (DLBCL)

Italy
M.D. Anderson Cancer Center
Takeda

Withdrawn

Study of Brentuximab Vedotin Plus TAK228 for Relapsed/Refractory Classical Hodgkin Lymphoma, Anaplastic Large Cell Lymphoma and Other CD30+Peripheral T-Cell Lymphomas

Anaplastic Large Cell Lymphoma | Classical Hodgkin Lymphoma | Malignant Neoplasms Stated as Primary Lymphoid Haematopoietic | CD30+ Peripheral T-cell Lymphoma
University Health Network, Toronto

Enrolling by invitation

Ultrastructural Collagen Markers in Ehlers Danlos Syndromes

Ehlers-Danlos Syndrome | Hypermobile EDS (hEDS) | Classical Ehlers-Danlos Syndrome

Canada
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Efficacy and Safety of Topiramate in the Prevention of Migraine

Migraine | Headache | Common Migraine | Classic Migraine
Alona Zer
Bristol-Myers Squibb

Unknown

Nivolumab and Ipilimumab in Classical Kaposi Sarcoma (CKS)

Classic Kaposi Sarcoma

Israel
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Efficacy and Safety of Two Doses of Topiramate Compared to Placebo and Propranolol in the Prevention of Migraine

Migraine | Headache | Common Migraine | Classic Migraine
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of the Efficacy and Safety of Topiramate in the Prevention of Migraine

Migraine | Headache | Common Migraine | Classic Migraine
University of Massachusetts, Amherst

Withdrawn

O2 Transport and Utilization in Health and Lung Disease

Oxidative Stress | COPD | Tetrahydrobiopterin Deficiency

United States
The Seventh Affiliated Hospital of Sun Yat-sen...
Huizhou Municipal Central Hospital; Dongguan Hospital of Traditional Chinese... and other collaborators

Recruiting

Development and Validation of a Postoperative Re-fracture Risk Model for Osteoporotic Spinal Fractures

Osteoporosis Fracture | Compression Fracture | Osteoporosis Vertebral | Perform PVP / PKP Treatment

China
Stanford University
University of Colorado, Denver

Completed

Pharmacokinetics of Ketamine in Infants and Children

The Pk of IV Ketamine in Children With Heart Disease

United States
Neurocrine Biosciences

Completed

Safety, Tolerability, and Pharmacokinetics of a Single Dose of NBI-98854 in Subjects With Mild,Moderate, or Severe Hepatic Insufficiency

Safety, Tolerability, and PK of NBI-98854 in Hepatically Impaired Subjects

United States
National Cancer Institute (NCI)

Not yet recruiting

Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

Classic Follicular Lymphoma | Follicular Lymphoma With Unusual Cytological Features
Merck Sharp & Dohme LLC

Recruiting

A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)

Melanoma | Lymphoma | Solid Tumor | Classical Hodgkin Lymphoma | Microsatellite-instability-high Solid Tumor

France, Germany, Italy, Netherlands, Sweden, United Kingdom, Brazil, Israel, Korea, Republic of, United States
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)

Withdrawn

Sunitinib Malate in Treating East African Patients With Kaposi Sarcoma

Classic Kaposi Sarcoma | AIDS-related Kaposi Sarcoma
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab & Brentuximab Vedotin Consolidation After Autologous SCT in Patients With High-Risk Classical Hodgkin Lymphoma

Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Classic Hodgkin Lymphoma

United States
Tel-Aviv Sourasky Medical Center

Unknown

Kidney Function in Patients With Bladder Exstrophy

Proteinuria | Renal Function | Classic Bladder Exstrophy | GFR

Israel
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Not yet recruiting

Pembrolizumab Plus Lenvatinib in Previously Treated Classic Kaposi Sarcoma (PULSAR)

Classic Kaposi Sarcoma | Kaposi Sarcoma | Refractory Kaposi Sarcoma
Applied Therapeutics, Inc.

Completed

Safety and Pharmacokinetics of AT-007 in Healthy Subjects and in Adult Subjects With Classic Galactosemia

Classic Galactosemia

United States
Applied Therapeutics, Inc.

Active, not recruiting

Clinical Benefit, Safety, PK and PD Study of AT-007 in Pediatric Subjects With Classic Galactosemia

Classic Galactosemia

United States
Academisch Ziekenhuis Maastricht

Completed

The Effect of Arginine on Classic Galactosemia (ARGALT)

Classic Galactosemia

Netherlands
University of Chicago

Completed

Pilot Study of Pembrolizumab Treatment for Disease Relapse After Allogeneic Stem Cell Transplantation

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Classical Hodgkin Lymphoma | B-cell Non-Hodgkin Lymphoma

United States
Allecra

Completed

Pharmacokinetics of Cefepime and AAI101 in Subjects With Renal Insufficiency and Healthy Subjects

PK in Patients With Various Degrees of Renal Impairment

Czechia, Hungary
National Cancer Institute (NCI)

Recruiting

Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

HIV Infection | Advanced Malignant Solid Neoplasm | Kaposi Sarcoma | Lung Carcinoma | Metastatic Malignant Solid Neoplasm | Unresectable Solid Neoplasm | Anal Carcinoma | Recurrent Classic Hodgkin Lymphoma | Refractory Classic Hodgkin Lymphoma

United States, Australia
Pfizer's Upjohn has merged with Mylan to form Viatris...

Terminated

An Open Label Pharmacokinetic Study Of Gabapentin In Japanese Subjects With Renal Impairment Including Hemodialysis

PK Properties Of Gabapentin In Subjects With Impaired Renal Function

Japan
Vitaflo International, Ltd

Active, not recruiting

Evaluation of TYR Sphere in France (TYR sphere Fra)

Tyrosinemia | AKU

France
Applied Therapeutics, Inc.

Active, not recruiting

AT-007 in Adult Subjects With Classic Galactosemia (CG)

Classic Galactosemia

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Rituximab in Treating Participants With Stage III-IV Classic Hodgkin Lymphoma

Classic Hodgkin Lymphoma | Lugano Classification Stage III Hodgkin Lymphoma AJCC v8 | Lugano Classification Stage IV Hodgkin Lymphoma AJCC v8

United States
University Medical Center Groningen

Completed

PK/PD of Ertapenem In Patients With TB

PK of Ertapenem in TB Patients

Netherlands
Genmab
AbbVie

Recruiting

A Study to Evaluate Adverse Events of Subcutaneous (SC) Epcoritamab Administered in the Outpatient Setting in Adult Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma and Classic Follicular Lymphoma

Diffuse Large B-Cell Lymphoma | Classic Follicular Lymphoma

United States, Puerto Rico
Sanofi
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of SAR444245 With or Without Other Anticancer Therapies for the Treatment of Adults and Adolescents With Relapsed or Refractory B Cell Lymphoma (Master Protocol) [Pegathor Lymphoma 205]

Diffuse Large B-cell Lymphoma | Classic Hodgkin Lymphoma

Chile, Spain, Argentina
Sarcoma Oncology Research Center, LLC
Aadi Bioscience, Inc.

Completed

Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers

Melanoma | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | Ewing Sarcoma | Non Small Cell Lung Cancer | Chordoma | Urothelial Carcinoma | Classical Hodgkin Lymphoma | PEComa | Desmoid Tumor | Epithelioid Sarcoma | Squamous Cell Carcinoma | MTOR Activating Mutation

United States
Pfizer

Completed

Post-Marketing Surveillance To Observe Safety And Efficacy Of Xyntha Solofuse Prefilled Syringe

Factor VIII Deficiency, Congenital | Hemophilia A, Congenital | Factor 8 Deficiency, Congenital | Autosomal Hemophilia A | Classic Hemophilia
National Cancer Institute (NCI)

Active, not recruiting

Brentuximab Vedotin and Combination Chemotherapy in Treating Children and Young Adults With Stage IIB, Stage IIIB, IVA, or IVB Hodgkin Lymphoma

Ann Arbor Stage IIIB Hodgkin Lymphoma | Ann Arbor Stage IVA Hodgkin Lymphoma | Ann Arbor Stage IVB Hodgkin Lymphoma | Classic Hodgkin Lymphoma | Ann Arbor Stage IIB Hodgkin Lymphoma | Childhood Hodgkin Lymphoma

United States, Canada, Puerto Rico
University of Utah
National Institute of Allergy and Infectious Diseases (NIAID); Duke University and other collaborators

Completed

Hyperphenylalaninemia in Cerebral Malaria

Plasmodium Falciparum Malaria

Tanzania
Bispebjerg Hospital

Completed

IGF-I Stimulation of Collagen Synthesis in Ehlers-Danlos Patients

Ehlers-Danlos Syndrome, Classic

Denmark
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Active, not recruiting

Doxorubicin, Vinblastine, Dacarbazine, Brentuximab Vedotin, and Nivolumab in Treating Patients With Stage I-II Hodgkin Lymphoma

Classic Hodgkin Lymphoma | Ann Arbor Stage IB Hodgkin Lymphoma | Ann Arbor Stage II Hodgkin Lymphoma | Ann Arbor Stage IIA Hodgkin Lymphoma | Ann Arbor Stage IIB Hodgkin Lymphoma | Ann Arbor Stage I Hodgkin Lymphoma | Ann Arbor Stage IA Hodgkin Lymphoma

United States
Arizona State University
Washington State University

Enrolling by invitation

Preventing Speech and Language Disorders in Children With Classic Galactosemia

Language Disorders in Children | Classic Galactosemia | Speech Disorders in Children

United States
M.D. Anderson Cancer Center

Active, not recruiting

Modified Immune Cells (AFM13-NK) and A Monoclonal Antibody (AFM13) in Treating Patients With Recurrent or Refractory CD30 Positive Hodgkin or Non-Hodgkin Lymphomas

Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Mycosis Fungoides | Refractory Mycosis Fungoides | Recurrent Classic Hodgkin Lymphoma | Refractory Classic Hodgkin Lymphoma | Refractory Anaplastic Large Cell Lymphoma | Recurrent Anaplastic Large Cell Lymphoma and other conditions

United States
Radboud University Medical Center

Completed

The Pharmacokinetics and Pharmacodynamics of Eculizumab in Patients With Paroxysmal Nocturnal Hemoglobinuria (PREPARE)

Paroxysmal Nocturnal Hemoglobinuria | Eculizumab | PK-PD

Netherlands
MacroGenics

Recruiting

A Study of MGD024 in Patients With Relapsed or Refractory Hematologic Malignancies

Myelodysplastic Syndromes | Chronic Myeloid Leukemia | Classical Hodgkin Lymphoma | Blastic Plasmacytoid Dendritic Cell Neoplasm | Leukemia, B-cell | Leukemia, Hairy Cell | Leukemia, Acute Myeloid | Mastocytosis, Aggressive Systemic

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab and Brentuximab Vedotin in Treating Older Patients With Untreated Hodgkin Lymphoma

Ann Arbor Stage III Hodgkin Lymphoma | Ann Arbor Stage IIIA Hodgkin Lymphoma | Ann Arbor Stage IIIB Hodgkin Lymphoma | Ann Arbor Stage IV Hodgkin Lymphoma | Ann Arbor Stage IVA Hodgkin Lymphoma | Ann Arbor Stage IVB Hodgkin Lymphoma | Classic Hodgkin Lymphoma | Ann Arbor Stage IB Hodgkin Lymphoma | Ann... and other conditions

United States
University Hospital, Essen
Federal Ministry of Education and Reserach (BMBF)

Completed

Cardiovascular Diseases in HIV-infected Subjects (HIV-HEART Study)

Detection of Frequency, Severity and Progression of Cardiovascular Diseases in Patients With HIV-infection. | Effect on Cardiovascular Risk and Life Quality by Age, Gender, Classic Cardiovascular Risk Factors, | HIV-specific Cardiovascular Risk Factors, Cardiovascular Medication, Antiretroviral...

Germany
Crinetics Pharmaceuticals Inc.

Recruiting

Evaluate the Safety, Efficacy, and Pharmacokinetics of CRN04894 in Participants With Congenital Adrenal Hyperplasia (TouCAHn)

Congenital Adrenal Hyperplasia | Classic Congenital Adrenal Hyperplasia

Brazil, India, United States, Argentina, Italy, United Kingdom
Hospices Civils de Lyon

Completed

Fertility and Pregnancy in Patients With Classic Congenital Adrenal Hyperplasia (FERTI-HCS)

Classic Congenital Adrenal Hyperplasia

France
National Cancer Institute (NCI)
The Lymphoma Academic Research Organisation

Active, not recruiting

Brentuximab Vedotin and Combination Chemotherapy in Treating Patients With Stage II-IV HIV-Associated Hodgkin Lymphoma

HIV Infection | Ann Arbor Stage III Hodgkin Lymphoma | Ann Arbor Stage IIIA Hodgkin Lymphoma | Ann Arbor Stage IIIB Hodgkin Lymphoma | Ann Arbor Stage IV Hodgkin Lymphoma | Ann Arbor Stage IVA Hodgkin Lymphoma | Ann Arbor Stage IVB Hodgkin Lymphoma | Classic Hodgkin Lymphoma | Ann Arbor Stage II Hodgkin... and other conditions

United States, France

Clinical Trials on Classical Phenylketonuria(PKU)

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