Clinical Trials on Clinical Pharmacology

Total 2867 results

Yale University
University Hospitals Cleveland Medical Center; Shockwave Medical, Inc.

Recruiting

CRUSH PAD: Real-world Outcomes Following Use of the Shockwave Intravascular Lithotripsy (IVL) Technology in Calcified Common Femoral Lesions

Peripheral Arterial Disease | Claudication | Critical Limb Ischemia | Femoral Arterial Calcification

United States
Heinrich-Heine University, Duesseldorf

Recruiting

Outcomes and Prognostic Factors in COVID-19 (COVIP)

COVID-19 | Critical Illness | Elderly Patients | Old Age | Survival

Germany, Denmark, France, Norway
University of Alberta
Alberta Innovates Health Solutions; Institute of Health Economics, Canada

Recruiting

Implementation of CRRT KPI Reports to Standardize and Improve the Quality of CRRT Delivery in Alberta "QUALITY CRRT" (QUALITY-CRRT)

Critical Illness | Acute Kidney Failure

Canada
University of Zurich

Active, not recruiting

The RIsk Stratification in COVID-19 Patients in the ICU Registry (RISC-19-ICU)

COVID-19 | Critical Illness | Inflammatory Response | ARDS | Circulatory Shock

Switzerland
Atrial Fibrillation Network

Completed

Prospective Registration and Assessment of Serious Adverse Events Within the AFNET (AFNET A7)

Atrial Fibrillation | Assessment of Serious Advers Events | Thromboembolic and Bleeding Complications | Complications of Antiarrhythmic Drugs or Invasive Procedures | Assessment by a Critical Event Committee

Germany
Tampa Bay Uveitis Center, LLC
Mallinckrodt

Completed

Study of H.P. ACTHAR Subcutaneous Gelatin (Gel)(Highly Purified Gel Injection) in Uveitis Patients

Uveitis | Posterior Uveitis | Intermediate Uveitis | Anterior Uveitis | Scleritis | Clinically Significant Macular Edema

United States
Massachusetts General Hospital

Unknown

Predictors of Upper Airway Function and Sleep-disordered Breathing in the Critically Ill

Obstructive Sleep Apnea | Critically Ill

United States
Zhongda Hospital

Unknown

Renal Resistive Index and Cardiac Output Changes During Resuscitation Predict the Occurrence of Acute Kidney Injury in Septic Shock Patients (CORRI)

Septic Shock | Acute Kidney Injury | Critically Ill

China
Fraser Health
University of Victoria

Recruiting

pEEG Monitoring Effect on Delirium, Ventilator Days, and PICS

Delirium | Critical Illness | Analgesia | Mechanical Ventilation Complication | Post Intensive Care Unit Syndrome | Post Intensive Care Syndrome | Sedative-Related Disorders; Subsequent Encounter

Canada
Hospital de Clinicas de Porto Alegre

Recruiting

VExUS-guided Fluid Management in Patients With Acute Kidney Injury in the Intensive Care Unit (AKIVEX)

Critical Illness | Acute Kidney Injury | Fluid Overload | Renal Insufficiency, Acute | Volume Overload | Kidney; Disease, Acute

Brazil
Guowei Tu

Recruiting

Predicting Poor Outcomes of Cardiac Surgery-Associated Acute Kidney Injury Using Novel Biomarkers

Critical Illness | Acute Kidney Injury

China
Karolinska University Hospital

Recruiting

Timing of Renal Replacement Therapy in the Critically Ill Patients (TORRT)

Critical Illness | Acute Kidney Injury | Fluid Overload | Uremia | Dialysis; Complications

Sweden
LimFlow, Inc.

Completed

PROMISE I Early Feasibility Trial of the LimFlow Stent Graft System

Critical Limb Ischemia | Chronic Limb-Threatening Ischemia

United States
Kyungmin Huh

Terminated

FilmArray Pneumonia Panel for Antimicrobial Treatment of HAP/VAP in Intensive Care Units (FilmArray)

Critically Ill | Pneumonia, Ventilator-Associated | Pneumonia, Hospital Acquired

Korea, Republic of
University of Calgary
Canadian Institutes of Health Research (CIHR)

Active, not recruiting

Partnering With Family Members to Prevent, Detect and Manage Delirium in Critically Ill Patients.

Delirium | Post Intensive Care Unit Syndrome | Intensive Care Unit Delirium | Post Intensive Care Unit Syndrome Family

Canada
Basri Cakiroglu

Completed

Comparison of the Results of Bronchoalveolar Lavage Culture and Endotracheal Aspirate Culture in Intubated Critically Ill COVID-19 Patients

Critical Illness | COVID-19 Pneumonia | Bronchoalveolar Lavage

Turkey
Medical University of Graz

Completed

ICU Trial in Critical Ill COVID-19 Patients (POINT-C)

Critical Illness | Covid19 | Risk Factor, Cardiovascular | Course Illness

Austria
Galera Therapeutics, Inc.

Terminated

A Trial of GC4419 in Patients With Critical Illness Due to COVID-19

Covid19 | SARS-CoV-2 Infection

United States
MultiGene Vascular Systems Ltd.

Active, not recruiting

Safety Study of MultiGeneAngio in Patients With Chronic Critical Limb Ischemia

Peripheral Arterial Disease | Peripheral Vascular Disease | Critical Limb Ischemia

Israel
M.D. Anderson Cancer Center

Recruiting

Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Antibodies

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Advanced Malignant Solid Neoplasm | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Clinical Stage III Cutaneous Melanoma AJCC v8 and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Nutritional Supplementation in Reducing Complications in Patients With Locally Advanced Esophageal Cancer Undergoing Chemotherapy, Radiation Therapy, and/or Surgery

Clinical Stage III Esophageal Adenocarcinoma AJCC v8 | Clinical Stage III Esophageal Squamous Cell Carcinoma AJCC v8 | Pathologic Stage III Esophageal Adenocarcinoma AJCC v8 | Pathologic Stage III Esophageal Squamous Cell Carcinoma AJCC v8 | Pathologic Stage IIIA Esophageal Adenocarcinoma... and other conditions

United States
National Cancer Institute (NCI)

Suspended

A Study Evaluating Whether Pembrolizumab Alone or in Combination With CMP-001 Improves Efficacy in Patients With Operable Melanoma

Clinical Stage III Cutaneous Melanoma AJCC v8 | Melanoma of Unknown Primary | Pathologic Stage IIIB Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Pathologic Stage IIID Cutaneous Melanoma AJCC v8 | Recurrent Cutaneous Melanoma

United States
Alliance for International Medical Action
Institut National de la Santé Et de la Recherche Médicale, France; University... and other collaborators

Recruiting

Lassa Fever Clinical Course and Prognostic Factors in Nigeria (LASCOPE)

Pregnancy Complications | Acute Kidney Injury | Coma | Acute Kidney Failure | Lassa Fever | Lassa Virus Infection

Nigeria
Haseki Training and Research Hospital

Recruiting

Acute Kidney Injury in Intensive Care Patients (AKI-ICU)

Critical Illness | Acute Renal Injury

Turkey
Children's Hospital of Fudan University
Shanghai Children's Hospital; Shanghai Children's Medical Center; Xinhua Hospital... and other collaborators

Recruiting

Study on Early Genetic Screening and Precise Strategy of Neonatal Critical Illness

Newborn | Stillbirth | Genetic Screening | Hereditary Disease

China
Mt. Sinai Medical Center, Miami

Recruiting

Trial to Assess Chelation Therapy in Critical Limb Ischemia (TACT3a)

Diabetes | Critical Limb Ischemia

United States
University of Ulm

Completed

Critically Ill ICU Patients Under Casirivimab- and/or Tocilizumab Application (CasiTocCOVID)

COVID-19 | Critically Ill | Outcome, Fatal | Interleukin 6 | Tocilizumab

Germany
University of Wisconsin, Madison
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

A Study of Communication Between Clinicians, Patients, and Families in the Intensive Care Unit (ICU) (TIME)

Communication | Palliative Care | Critical Care | Acute Respiratory Failure | Mechanical Ventilation | Decision Making | Life-Supporting Treatments

United States
University of Alberta

Completed

Using AtorVASTatin to Prevent VAscular Inflammatory OccLUSion in the Critically Ill (VASTVALUS)

Myocardial Infarction | Stroke | Renal Failure

Canada
Vésale Hospital
Janssen-Cilag Ltd.

Completed

Onychomycosis: Diagnosis and Prevalence in Diabetic Neuropathic Patients

Prevalence of Onychomycosis | Diabetic Neuropathic Patients | Diagnostic of Onychomycosis | Patients Clinically Suspected of Onychomycosis | Reliability of the Diagnosis of Onychomycosis

Belgium
Hospital do Cancer, Sao Paulo

Completed

Saline Instillation Before Tracheal Suctioning and the Incidence of Ventilator Associated Pneumonia

Critically Ill Patients | Mechanical Ventilation

Brazil
Universidad del Norte

Unknown

Piperacillin/Tazobactam Versus Carbapenems in Non-bacteremic UTI Due to -ESBL-producing Enterobacteriaceae (CAPITIS)

Urinary Tract Infections | Enterobacteriaceae Infections | Clinical Trial | Carbapenem | Klebsiella Pneumoniae Infection | Infection Due to ESBL Bacteria | Escherichia Coli Infection | Drug Resistance, Bacterial

Colombia
Shanghai Zhongshan Hospital
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University and other collaborators

Not yet recruiting

Predicting Adverse Kidney Events of Cardiac Surgery-Associated Acute Kidney Injury Using Novel Biomarkers

Critical Illness | Acute Kidney Injury | Kidney Failure

China
Southeast University, China

Not yet recruiting

Ultrasound to Evaluate Acute Kidney Injury

Acute Kidney Injury | Critically Ill

China
Xiangya Hospital of Central South University

Not yet recruiting

The Effect of BIA Monitoring of Brain Edema on the Neurological Prognosis of Supratentorial Massive ICH (BIATICH)

Intracranial Hypertension | Critical Care | Monitoring | Treatment Outcome | Cerebral Hemorrhage, Hypertensive | Bioelectrical Impedance Analysis

China
Xim Limited

Completed

The Measurement of VItal SIgns by Lifelight® Software in comparisON to the Standard of Care - Multi-site Development (VISION-MD)

Cardiovascular Diseases | Diabetes | Critical Care | Primary Care | Respiratory Disorder | Trauma and Emergency Care

United Kingdom
Jing Liang

Recruiting

Correlation Between the Change of Peripheral Lymphocyte Subsets and Clinically Amyopathic Dermatomyositis Combined With Rapidly Progressive Interstitial Lung Disease

Clinically Amyopathic Dermatomyisitis(CAMD)

China
Federico II University

Not yet recruiting

LegDeb2 Global Registry for Use of Legflow in Peripheral Arteries (LEGDEB2)

Arterial Occlusive Diseases | Peripheral Arterial Disease | Popliteal Artery Stenosis | Critical Limb Ischemia | Superficial Femoral Artery Stenosis | Iliac Artery Stenosis

Italy, Mexico
Boston Medical Center
Abbott; Vascular & Endovascular Surgery Society

Recruiting

Nutrition in Patient With Critical Limb Ischemia (NutriVasc)

Malnutrition | Critical Limb Ischemia | Nutritional Supplements

United States
Hasselt University
Jessa Hospital

Completed

Skeletal Muscle Wasting in SARS-CoV-2 (SMW)

Critical Illness | Cachexia | Muscle Atrophy | Muscle Loss | Muscle Wasting

Belgium
Mansoura University

Completed

The Impact of COVID-19 Pandemic on Critical Limb Threatening Ischemia and Emergency Vascular Practice

COVID | Critical Limb Ischemia

Egypt
Ataturk University

Completed

Oxygen Saturation and Perfusion Index ın Neonates at High Altitude

High Altitude | Critical Congenital Heart Disease

Turkey
Barts & The London NHS Trust
Queen Mary University of London

Recruiting

Recovery From ICUAW Following Severe Respiratory and Cardiac Failure (CLEVERER)

Respiratory Failure | Acute Respiratory Distress Syndrome | Critical Illness Myopathy | Intensive Care Unit Syndrome | Cardiac Failure | Intensive Care (ICU) Myopathy | Intensive Care Neuropathy

United Kingdom
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer

Peritoneal Carcinomatosis | Stage IV Uterine Corpus Cancer AJCC v8 | Stage IVA Uterine Corpus Cancer AJCC v8 | Stage IVB Uterine Corpus Cancer AJCC v8 | Metastatic Malignant Solid Neoplasm | Malignant Uterine Neoplasm | Clinical Stage IV Gastric Cancer AJCC v8 | Metastatic Colorectal Carcinoma | Stage... and other conditions

United States
Ain Shams University

Recruiting

Value of Early Post Operative Amino Acids in Critically Ill Obstetrics on Recovery Enhancement

Critical Illness | Patient Satisfaction | Postpartum Disorder | Malnutrition; Protein | Malnutrition in Pregnancy

Egypt
Careggi Hospital
University of Florence

Active, not recruiting

Development of a Web-based Multicenter Registry on the Use of oXiris Membrane for EBPTs in Critically Ill Patients

Sepsis | Systemic Inflammatory Response Syndrome | Critical Illness | Acute Kidney Injury

Italy
Sanjay Gandhi Postgraduate Institute of Medical...

Completed

Gastroesophageal Reflux Disease (GERD) Among ICU Survivors

Gastroesophageal Reflux Disease | Critically Ill

India
Instituto Universitario de Oftalmobiología Aplicada...
Hospital del Río Hortega; Fundación Eugenio Rodríguez Pascual

Enrolling by invitation

Visual Processing Speed and Objective Analysis of Ocular Movements in Multiple Sclerosis

Progressive Multiple Sclerosis | Multiple Sclerosis | Clinically Isolated Syndrome | Relapsing Remitting Multiple Sclerosis

Spain
Gunnar Lachmann

Completed

Investigation of Ferritin in Critically Ill Patients With Hemophagocytic Lymphohistiocytosis (FERRITS)

Hemophagocytic Lymphohistiocytosis (HLH) | Macrophage Activation Syndrome (MAS) | Hemophagocytic Syndromes
Abbott Medical Devices

Terminated

The ABSORB BTK (Below The Knee) Clinical Investigation

Atherosclerosis | Peripheral Arterial Occlusive Disease | Peripheral Vascular Disease | Peripheral Artery Disease | Claudication | Critical Limb Ischemia | PAD | PVD | Lower Limb Disease | PAOD

Belgium

Clinical Trials on Clinical Pharmacology

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Guinea

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations