Clinical Trials on Clostridium; Sepsis in Germany

Total 187 results

University of Rostock

Completed

Extracorporeal Immune Support System (EISS) for the Treatment of Septic Patients (EISS-1)

Severe Sepsis and Septic Shock

Germany
University Medicine Greifswald

Unknown

Bedside vs. Standard Microbiological Blood Culture Diagnostics - BEMIDIA Study (BEMIDIA)

Sepsis Septic Shock

Germany
Klinikum Emden
Universitätsklinikum Hamburg-Eppendorf; Kantonsspital Baden; Kantonsspital Münsterlingen

Completed

Evaluating a CytoSorb Score in Septic Shock (ECSISS)

Severe Sepsis With Septic Shock

Germany
Charite University, Berlin, Germany

Completed

IL 6 Measurement Using a New Densitometric Bedside (POC) Test

Sepsis, Septic Shock

Germany
German Center for Neurodegenerative Diseases (DZNE)
University Hospital, Bonn

Unknown

Long-term Cognitive and Cerebral Changes in Sepsis Survivors and Their Predictors (BonSEP)

Severe Sepsis With Septic Shock | Severe Sepsis Without Septic Shock

Germany
Universitätsmedizin Mannheim

Completed

Microcirculatory Oxygen Uptake in Sepsis

Sepsis | Septic Shock | Severe Sepsis

Germany
Center for Sepsis Control and Care, Germany
Hannover Medical School; German Federal Ministry of Education and Research; University... and other collaborators

Completed

Quality Improvement in Infection COntrol and Sepsis Management in MOdel Regions (icosmos)

Sepsis | Septic Shock | Severe Sepsis

Germany
Universitätsmedizin Mannheim

Recruiting

Mannheim Register of Sepsis and Septic Shock (MARSS)

Septic Shock | Severe Sepsis

Germany
Johannes Gutenberg University Mainz

Withdrawn

Cerebrovascular Autoregulation in Sepsis, Influence of Renal Replacement Therapy (SepsAR2)

Septic Shock | Severe Sepsis

Germany
InflaRx GmbH

Completed

Studying Complement Inhibition in Early, Newly Developing Septic Organ Dysfunction (SCIENS)

Septic Shock | Severe Sepsis

Germany
RWTH Aachen University

Completed

German Lactat Clearance in Severe Sepsis (GLASS)

Septic Shock | Severe Sepsis

Germany
Universitätsklinikum Hamburg-Eppendorf
CytoSorbents, Inc

Recruiting

Adjuvant Therapy With CytoSorb in Refractory Septic Shock (ACYSS)

Septic Shock

Germany
Claudia Spies

Completed

Clock Genes in Patients With Refractory Septic Shock (SeptiClock) - Pilot Study

Septic Shock

Germany
Johannes Gutenberg University Mainz

Unknown

Improvement of Cerebrovascular Autoregulation in Patients With Septic Shock Due to Cytokine Elimination (SepsAR3)

Septic Shock

Germany
Universitätsklinikum Hamburg-Eppendorf

Completed

Examination of ADMA Serum Level and DDAH II (ADSeS)

Sepsis | Septic Shock

Germany
Charite University, Berlin, Germany

Recruiting

Evaluation of Parameters Collected From Routine Data for the Diagnosis of Sepsis and Septic Shock and Their Influence on Time to Diagnosis and Patient Outcome

Sepsis | Septic Shock

Germany
University of Jena

Unknown

Jena Sepsis Registry (JenaSepsisReg)

Severe Sepsis or Septic Shock (ICD-10-GM, R65.0, R65.1)

Germany
University Hospital Tuebingen

Unknown

Fecal Microbiota Transplantation in Recurrent or Refractory Clostridium Difficile Colitis (TOCSIN)

Clostridium Difficile Infection | Clostridium Difficile

Germany
University Hospital Muenster

Active, not recruiting

Analysis of Sublingual Glycocalyx Damage at ICU Admission to Predict Risk of Death (ASGARD)

Sepsis | Septic Shock | Endothelial Dysfunction

Germany
Hannover Medical School

Unknown

Plasmaexchange in Early Septic Shock (EXCHANGE)

Septic Shock

Germany
SepNet - Critical Care Trials Group
Novo Nordisk A/S; German Federal Ministry of Education and Research; B. Braun... and other collaborators

Completed

Efficacy of Volume Substitution and Insulin Therapy in Severe Sepsis (VISEP Trial)

Septic Shock | Severe Sepsis

Germany
Hannover Medical School

Completed

Therapeutic Plasmaexchange in Early Septic Shock (EXCHANGE)

Septic Shock

Germany
Claudia Spies

Completed

Thermodilution - Controlled Management of Volume Therapy in Septic Shock (THEMIS)

Septic Shock | Volume Status

Germany
RWTH Aachen University

Recruiting

Observational Trial on Cytokine Adsorption in Sepsis (OuTCASt)

Sepsis | Septic Shock | Multiple Organ Failure

Germany
Kompetenznetz Sepsis
Biosyn; Brahms AG

Completed

Placebo Controlled Trial of Sodium Selenite and Procalcitonin Guided Antimicrobial Therapy in Severe Sepsis (SISPCT)

Septic Shock | Severe Sepsis

Germany
Sphingotec GmbH
Cliniques universitaires Saint-Luc- Université Catholique de Louvain; Hopital... and other collaborators

Completed

Adrenomedullin and Outcome in Severe Sepsis and Septic Shock (AdrenOSS)

Septic Shock | Severe Sepsis

France, Belgium, Germany, Italy, Netherlands
Kompetenznetz Sepsis
Bayer; AstraZeneca

Completed

Comparison of Two Antibiotic Regimen (Meropenem Versus Meropenem+Moxifloxacin)in the Treatment of Severe Sepsis and Septic Shock (MaxSep)

Septic Shock | Severe Sepsis

Germany
Center for Sepsis Control and Care, Germany
Center for Clinical Studies, University Hospital Jena, Germany; Dept. of Microbiology... and other collaborators

Completed

(1,3)-β-D-glucan Based Diagnosis of Invasive Candida Infection in Sepsis (CandiSep)

Septic Shock | Severe Sepsis

Germany
University Hospital Heidelberg

Completed

Anticholium® Per Se

Sepsis | Shock, Septic | Perioperative Period

Germany
CytoSorbents Europe GmbH
BRAHMS GmbH; MedInnovation GmbH

Recruiting

A RCT to Assess the Performance of CytoSorb for Shock Reversal in Patients With Vasoplegic Septic Shock (PROCYSS)

Septic Shock

Germany
Astellas Pharma Europe Ltd.
Cubist Pharmaceuticals LLC

Terminated

A Post-marketing, Blinded Study to Investigate How Effective Fidaxomicin is Compared to Vancomycin in the Sustained Cure of Clostridium Difficile Infection in Adults That Are Receiving Therapy to Suppress the Immune System (FREEDOM)

Clostridium Difficile

Spain, France, Germany, Greece, Denmark, Austria, Poland
Hannover Medical School

Not yet recruiting

Efficacy of add-on Plasma Exchange as an Adjunctive Strategy Against Septic Shock (EXCHANGE-2)

Septic Shock

Switzerland, Austria, Germany
Jena University Hospital
German Research Foundation; Instituto Grifols, S.A.; University Hospital Goettingen and other collaborators

Recruiting

Albumin Replacement Therapy in Septic Shock (ARISS)

Septic Shock

Germany
Astellas Pharma Europe B.V.

Terminated

To Determine the Feasibility of a Fidaxomicin Study in Neonates and to Assess C. Difficile (Clostridium Difficile) Involvement in the Pathogenesis (DAISY)

Clostridium Difficile

France, Germany, Netherlands, Spain
University of Leipzig

Recruiting

Rotational Thromboelastometry Versus DIC Score in Sepsis (RODSS)

Sepsis | Septic Shock

Germany
MJM Bonten
Universiteit Antwerpen; Universitätsklinikum Köln; Da Volterra

Completed

AssessmeNT of the Incidence of Clostridium Difficile Infections in Hospitalized Patients on Antibiotic TrEatment (ANTICIPATE)

Clostridium Difficile

Germany, Spain, France, Greece, Netherlands, Romania
Adrenomed AG

Completed

Treatment of Patients With Early Septic Shock and Bio-Adrenomedullin(ADM) Concentration > 70 pg/ml With ADRECIZUMAB (AdrenOSS-2)

Septic Shock

France, Belgium, Germany, Netherlands
Jena University Hospital
Department of Anesthesiology and Intensive Care Medicine, JUH; Department of... and other collaborators

Completed

Identification of Cardiovascular and Molecular Prognostic Factors for the Mid- and Long-term Outcome of Sepsis (ICROS)

Sepsis | Cardiomyopathies | Septic Cardiomyopathy

Germany
University of Cologne

Unknown

Incidence and Economic Burden of Clostridium Difficile Infections (CDI) in the German Health Care System (IBIS) (IBIS)

Clostridium Difficile Infection | Clostridium Difficile Diarrhea

Germany
Valneva Austria GmbH

Completed

Dose-Confirmation, Immunogenicity and Safety Study of the Clostridium Difficile Vaccine Candidate VLA84 in Healthy Adults Aged 50 Years and Older. Phase II Study

Clostridium Difficile

Germany, United States
University Hospital of Cologne
Charite University, Berlin, Germany; University Hospital Tuebingen; University... and other collaborators

Completed

Antibiotic Stewardship and Infection Control in Patients at High Risk of Developing Infection by Clostridium Difficile, Vancomycin-Resistant Enterococci or Multi-Resistant Gram-Negatives (ABSOLUTE)

Clostridium Difficile Infection | Nosocomial Infection | VRE Infection | MRGN Bacteria

Germany
University Hospital Tuebingen
University of Giessen; University Hospital Freiburg; Universitätsklinikum Köln; University Hospital Lübeck and other collaborators

Unknown

Bloodstream Infection Due to Multidrug-Resistant Organisms - Multicenter Study on Determinants of Clinical Outcomes (BLOOMY-COM)

Septic Shock | Bloodstream Infection

Germany
RWTH Aachen University
Biotest

Recruiting

Prospective, Randomized Trial of Personalized Medicine With Pentaglobin® After Surgical Infectious Source Control in Patients With Peritonitis (PEPPER Trial). (PEPPER)

Sepsis | Septic Shock | Peritonitis

Austria, Germany
University of Cologne

Unknown

MicroTrans - A Multicenter Registry of Fecal Microbiota Transplantation (MicroTrans)

Clostridium Infections

Germany
University Medicine Greifswald
Fresenius AG

Completed

The Benefit of Adding Fish Oil to the Nutrition of Critically Ill Patients

Sepsis Syndrome

Germany
Charite University, Berlin, Germany
German Research Foundation; adexter GmbH

Completed

Immunoadsorption of LPS, C5a and IL-6 in Severe Sepsis and Septic Shock (ISASS-1)

Septicemia

Germany
University of Minnesota
Merck Sharp & Dohme LLC; Astellas Pharma Inc; Medical Research Council; Washington... and other collaborators

Completed

Observational Study of C. Diff in Post-Transplant Patients (CDIFF)

Clostridium Difficile

Spain, United States, Argentina, Denmark, Germany
University Hospital Heidelberg
Fraunhofer Institute for Interfacial Engineering and Biotechnology; Dietmar...

Completed

Next-Generation Sequencing Diagnostics of Bacteremia in Sepsis (NextGeneSiS)

Sepsis | Septic Shock

Germany
Artcline GmbH
ZKS Jena

Recruiting

Recovery From Acute Immune Failure in Septic Shock by Immune Cell Extracorporeal Therapy - Observational Long-term Outcome Follow up (ReActIF- LTO)

Severe Sepsis

Germany
Klinikum St. Georg gGmbH
University of Halle Medical Faculty

Terminated

Alterations of Immunologic Mediators During Severe Sepsis (LAVISS_01)

Severe Sepsis

Germany

Clinical Trials on Clostridium; Sepsis in Germany

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