Clinical Trials on Cocaine Use Disorder

Total 144331 results

Yale University

Terminated

A Drug Treatment for Cocaine Users Who Are Also on Methadone Maintenance Treatment

Cocaine Dependence | Opiate Dependence

United States
Hennepin Healthcare Research Institute
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Recruiting

EXHIT ENTRE Comparative Effectiveness Trial (EXHITENTRE)

Substance Use Disorder | Opioid Use Disorder, Moderate | Opioid Use Disorder, Severe

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Glutamate-Glutamine Cycling (VCYC) During Cocaine Abstinence Using 1H-MRS

Healthy | Cocaine Dependence

United States
The University of Texas Health Science Center,...
National Institute on Drug Abuse (NIDA); University of Texas

Completed

Impulsivity, Brain Function, and Substance Abuse Treatment in Cocaine Dependent Individuals

Cocaine-Related Disorders | Cocaine Abuse

United States
University of Arkansas
National Institute on Drug Abuse (NIDA)

Completed

Clinical Efficacy of Sertraline Augmented With Gabapentin in Depressed, Recently Abstinent Cocaine-dependent Humans

Depressive Symptoms | Cocaine Dependence

United States
Paul Saenger

Unknown

A Double-Blind, Controlled Study of Aripiprazole in Co-Morbid Schizophrenia and Cocaine Dependence

Schizophrenia | Cocaine Dependence

United States
Woebot Health
Stanford University

Completed

The Anchor Study: Digitally Delivered Intervention for Reducing Problematic Substance Use

Substance Use Disorders | Alcohol Use Disorder (AUD)

United States
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Completed

Human Behavioral Pharmacology Laboratory (HBPL) Study of Varenicline's Impact on Cocaine and Alcohol Craving

Alcohol Dependence | Cocaine Dependence

United States
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Completed

HBPL Study of the Impact of the NK1 Antagonist Aprepitant

Alcohol Dependence | Cocaine Dependence

United States
Medical University of South Carolina
National Institute on Drug Abuse (NIDA)

Completed

10 Days of Theta Burst Stimulation as a Tool to Treat Cocaine Dependence

Alcohol Dependence | Cocaine Dependence

United States
Woebot Health
National Institute on Drug Abuse (NIDA); Stanford University

Completed

Pilot: Digital Therapeutic vs Education for the Management of Problematic Substance Use

Substance Use Disorders | Alcohol Use Disorder (AUD)

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Investigation of Cocaine Addiction Using mGluR5 PET and fMRI

Cocaine Dependence

United States
Bryon Adinoff
National Institute on Drug Abuse (NIDA)

Completed

Lidocaine Infusion as a Treatment for Cocaine Relapse and Craving (LIDO)

Cocaine Addiction

United States
Erasmus Medical Center

Completed

Effects of tDCS on Craving, Relapse and Cognitive Functions Among Patients With Cocaine Use Disorder

Cocaine Addiction

Netherlands
Psychiatric University Hospital, Zurich
Swiss Federal Institute of Technology; Zurich Center for Integrative Human... and other collaborators

Completed

Neurobiological Adaptations and Pharmacological Interventions in Cocaine Addiction (CoGlu)

Cocaine Addiction

Switzerland
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Cocaine Withdrawal and Pharmacotherapy Response (Carvedilol)

Cocaine Dependence | Opiate Dependence

United States
Prof. Dominique de Quervain, MD
Psychiatric Hospital of the University of Basel

Terminated

Effects of Glucocorticoids on Craving During Detoxification Treatment of Heroin and/or Stimulants (Goliath)

Opioid Dependence | Cocaine Dependence

Switzerland
Baylor College of Medicine
National Institute on Drug Abuse (NIDA); Yale University

Completed

Pharmacogenetics of Disulfiram for Cocaine (Disulfiram)

Opioid Dependence | Cocaine Dependence

United States
Yale University

Completed

Levetiracetam (Keppra) Tolerability in Cocaine Abusing Methadone-maintained Patients. (Keppra)

Opioid Dependence | Cocaine Dependence

United States
National Institute on Drug Abuse (NIDA)

Completed

Effect of Clonidine on Responses to Imagery Scripts

Cocaine Abuse | Heroin Abuse

United States
Chang Gung University
Chang Gung Memorial Hospital

Completed

The Impact of Exergame on User Health

Impact of Exergame Use on User Health

Taiwan
Mclean Hospital
National Institute on Drug Abuse (NIDA)

Completed

Families With Substance Use and Psychosis: A Pilot Study

Schizophrenia | Schizoaffective Disorder | Tobacco Use | Bipolar Disorder | Cannabis | Substance Use | Substance Use Disorders | Psychosis | Alcohol Use Disorder | Mental Disorder | Cigarette Smoking | Nicotine Use Disorder | Family | Marijuana | Alcohol

United States
National Institute on Drug Abuse (NIDA)
National Alliance for Research on Schizophrenia and Depression

Completed

Metabolic Effects of Cocaine

Cocaine Dependence

United States
University of North Carolina, Chapel Hill

Completed

Ultrabrief Behavioral Activation for Reducing Alcohol Use (UBA)

Alcohol Use Disorder, Mild | Alcohol Use Disorder, Moderate

United States
University of Maryland, Baltimore
National Institute on Drug Abuse (NIDA)

Completed

Integrative Meditation (IM) for Cocaine Addiction

Cocaine Addiction

United States
Medical University of South Carolina

Completed

Enhancing Disrupted Reconsolidation: Impact on Cocaine Craving

Cocaine Addiction

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Clinical Trial of Topiramate for Cocaine Addiction

Cocaine Dependence

United States
The University of Texas Health Science Center,...
National Institute on Drug Abuse (NIDA); University of Texas

Terminated

Pharmacotherapy Dosing Regimen in Cocaine and Opiate Dependent Individuals - 8

Opiate Dependence | Cocaine Abuse

United States
National Institute on Drug Abuse (NIDA)

Completed

Combined Behavioral and Pharmacologic Treatment of Polydrug Abuse

Opioid Dependence | Cocaine Abuse
The University of Texas Health Science Center,...
National Institute on Drug Abuse (NIDA)

Completed

Medications for Stopping Cocaine Dependence and Preventing Relapse

Cocaine-Related Disorders | Cocaine Abuse

United States
Hennepin Healthcare Research Institute
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Recruiting

EXHIT ENTRE Implementation Trial of High Intensity Versus Low Intensity Strategy (EXHITENTRE)

Substance Use Disorders | Opioid Use Disorder, Moderate | Opioid Use Disorder, Severe

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Therapeutic Substance Abuse Treatment in Pregnancy - 1 (PRIDE-P)

Marijuana Abuse | Alcohol Abuse | Cocaine Abuse

United States
National Institute on Drug Abuse (NIDA)
University of Maryland

Completed

Risk Perception in Drug-Dependent Adults With and Without Schizophrenia

Schizophrenia | Cannabis Dependence | Cocaine Dependence

United States
Ellen Herbst
Tobacco Related Disease Research Program

Recruiting

N-Acetylcysteine for Smoking Cessation in Tobacco and Cannabis Co-Use (NAC_CUD-TUD)

Tobacco Use Disorder | Cannabis Use | Drug Use Disorder

United States
Emory University
National Institute on Drug Abuse (NIDA); Georgia Institute of Technology; CUNY

Completed

Non-Invasive Vagal Nerve Stimulation in Opioid Use Disorders (nVNS in OUDs)

Substance-Related Disorders | Substance Abuse, Intravenous | Substance Use Disorders | Opioid Use | Substance Abuse | Opioid-use Disorder | Opioid Use Disorder, Severe | Substance Withdrawal

United States
VA Office of Research and Development
Oregon Health and Science University

Completed

Neurobiology of Alcohol and Nicotine Co-Addiction (NAUD)

Alcohol Use Disorder | Nicotine Use Disorder

United States
Catalyst Pharmaceuticals, Inc.

Completed

A Safety, Tolerability and Pharmacokinetic Study of CPP-115

Cocaine Dependency

United States
Albert Einstein College of Medicine
National Institute on Drug Abuse (NIDA); Pfizer; National Institutes of Health...

Active, not recruiting

A Trial of Directly Observed and Long-term Varenicline

Tobacco Use Disorder | Opioid-use Disorder

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Study of Adderall-XR for the Treatment of Adult Attention Deficit Hyperactivity Disorder and Cocaine Dependence (CAMP)

Cocaine Dependence | Adult Attention Deficit Hyperactivity Disorder

United States
Université du Québec à Trois-Rivières

Completed

My Choices: Efficacy and Implementation Study

Alcohol Use, Unspecified | Alcohol Use Disorder, Mild

Canada
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Modafinil, Sleep, and Cognition in Cocaine Dependence

Cocaine Dependence | Substance-induced Sleep Disorder | Substance-induced Cognitive Disorder

United States
University of Wisconsin, Madison
Revive Therapeutics, Ltd.

Recruiting

Study of the Safety and Feasibility of Psilocybin in Adults With Methamphetamine Use Disorder

Substance-Related Disorders | Chemically-Induced Disorders | Substance Use Disorders | Methamphetamine Use Disorder | Stimulant-Use Disorder

United States
Indivior Inc.

Completed

A Randomized, 4-sequence, 2-period, Double-blind, Placebo Controlled Study With a DSM-IV-TR Diagnosis of Cocaine Abuse (RBP-8000)

Opioid Dependence | Cocaine Dependence | Opioid Related Disorders

United States
University of Minnesota
National Cancer Institute (NCI)

Completed

Family-Skills Training to Prevent Tobacco and Other Substance Use in Latino Youth

Smoking | Alcohol Drinking | Tobacco Use Disorder | Alcohol Use Disorder | Drug Abuse | Drug Use Disorder

United States
Centre for Addiction and Mental Health

Completed

Effects of Corticorelin Administration on Dopamine Transmission, Craving, and Mood in Cocaine Dependence

Substance-Related Disorders | Cocaine-Related Disorders | Cocaine Addiction

Canada
University of Cincinnati
National Institute on Drug Abuse (NIDA)

Completed

Study of Buspirone for Relapse-Prevention in Adults With Cocaine Dependence (BRAC)

Cocaine Dependence

United States
University of Maryland, College Park
University of Maryland, Baltimore; National Center for Complementary and Integrative...

Completed

Peer-Delivered Behavioral Activation for Methadone Adherence - Pilot Phase (HEAL Together)

Substance Use | Substance Use Disorders | Opioid-use Disorder | Retention in Care | Methadone Treatment | Peer Delivered | Medication for Opioid Use Disorder (MOUD) | Behavioral Activation

United States
Vanderbilt University Medical Center

Completed

Evaluating the Impact of the Bridge Clinic in Patients With Opioid Use Disorder

Opioid Use | Opioid-use Disorder

United States
National Institute on Drug Abuse (NIDA)

Completed

Vigabatrin Ph 1 Cocaine Interaction Study

Cocaine Addiction

United States
Potomac Health Foundations
National Institutes of Health (NIH); National Institute of Drug Abuse

Recruiting

Peer Recovery Support Services for Individuals in Recovery Residences on MOUD

Substance Use Disorder | Opioid Use Disorder

United States

Clinical Trials on Cocaine Use Disorder

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