Clinical Trials on Cognitive Impairment, Progressive in New Zealand

Total 762 results

Tulane University
National Institute on Aging (NIA); Wake Forest University

Recruiting

Implementation of Multifaceted Patient-Centered Treatment Strategies for Intensive Blood Pressure Control in Minimize Cognitive Decline (IMPACTS-MIND)

Hypertension | Cognitive Decline

United States
Icahn School of Medicine at Mount Sinai
National Institute on Aging (NIA)

Completed

Elder Surgery - Functional Recovery Following Beta Blockade

Post Operative Cognitive Dysfunction

United States
Dartmouth-Hitchcock Medical Center

Recruiting

Use of Brain Wave Monitoring During Surgery to Reduce Postoperative Cognitive Dysfunction

Postoperative Cognitive Dysfunction

United States
Arthrosi Therapeutics
Iqvia Pty Ltd

Completed

Pharmacokinetic Study of AR882 in Subjects With Various Degrees of Renal Impairment

Renal Impairment

United States, New Zealand
Indiana University
National Institute on Aging (NIA); Alzheimer's Therapeutic Research Institute; Alzheimer's Association

Recruiting

Longitudinal Early-onset Alzheimer's Disease Study Protocol (LEADS)

Alzheimer Disease | Mild Cognitive Impairment | Early Onset Alzheimer Disease

United States
Columbia University

Recruiting

Autoimmune Features of Neurodegenerative Disorders

Parkinson Disease | Alzheimer Disease | Mild Cognitive Impairment

United States
Samuel Gandy

Completed

Amyloid and Tauopathy PET Imaging in Acute and Chronic Traumatic Brain Injury

Traumatic Brain Injury | Mild Cognitive Impairment | Chronic Traumatic Encephalopathy

United States
Taipei Medical University
Ministry of Science and Technology, Taiwan

Completed

Computerized Virtual Reality in Elderly

Quality of Life | Cognitive Dysfunction | Cognitive Change | Independent Living | Video Games

Taiwan
Albert Einstein College of Medicine
National Institute on Aging (NIA)

Completed

Cardiac Surgery Neuroprotection Study in Elders (CNS-Elders)

Post-operative Delirium | Post-operative Cognitive Decline

United States
Innate Immunotherapeutics
Syneos Health

Completed

Safety and Efficacy Study of MIS416 to Treat Secondary Progressive Multiple Sclerosis

Secondary Progressive Multiple Sclerosis

New Zealand, Australia
Yale University
National Alliance for Research on Schizophrenia and Depression

Completed

Galantamine for Cognitive Deficits in Schizophrenia

Schizophrenia

United States
University of California, San Francisco
New York University; Emory University

Completed

Correlation Between Montreal Cognitive Assessment and Voice Therapy Outcomes in the Aging Treatment- Seeking Population (MoCA)

Cognitive Impairment | Cognitive Decline | Voice Disorders | Swallowing Disorder | Voicebox Disorders

United States
Vanderbilt University Medical Center
University of Colorado, Denver; Beth Israel Deaconess Medical Center; Montefiore... and other collaborators

Completed

Vitamin D to Improve Outcomes by Leveraging Early Treatment: Long-term Brain Outcomes in Vitamin D Deficient Patients (VIOLET-BUD)

Cognitive Decline

United States
Columbia University

Not yet recruiting

Accelerated Age-related Cognitive Decline: Impact of Exercise on Executive Function and Neuroplasticity (EXEC)

Chronic Kidney Diseases | Mild Cognitive Impairment

United States
Pfizer

Completed

A Study Of Adjunctive Treatment Of Cognitive Deficits In Schizophrenia

Schizophrenia

United States
Centre for Addiction and Mental Health
National Institute of Mental Health (NIMH)

Active, not recruiting

RCT of Brain Longitudinal Biomarker Study (OPT-Neuro RCT) (ONR)

Depression | Dementia | Mild Cognitive Impairment | Major Depressive Disorder | Treatment Resistant Depression | Treatment-Refractory Depression | Late Life Depression | Geriatric Depression

United States, Canada
Allison Magnuson
National Institute on Aging (NIA)

Active, not recruiting

Feasibility of the Memory and Attention Adaptation-Training Geriatrics Intervention in Older Cancer Survivors With Mild Cognitive Impairment (urochester)

Cognitive Dysfunction

United States
Clalit Health Services

Unknown

MoCa Test for the Early Detection of Mild Cognitive Impairment During Annual Assessment of Young Adults With Diabetes and in a Control Group Without Diabetes

Diabetes Mellitus Type 2 | Mild Cognitive Impairment | Diabetes Mellitus Type 1

Israel
Woolcock Institute of Medical Research
National Health and Medical Research Council, Australia

Enrolling by invitation

The Effect of OSA on Brain Waste Clearance

Cognitive Impairment | Obstructive Sleep Apnea | Dementia

Australia
Region Skane
Lund University; Helsinki University Central Hospital; The George Institute for... and other collaborators

Recruiting

Stepcare Extended Follow-up Substudy

Cognitive Impairment | Caregiver Burden | Hypoxia, Brain | Cardiac Arrest With Successful Resuscitation

Sweden, Finland, New Zealand, Australia, Germany, Luxembourg
GE Healthcare
Covance; H2O Clinical LLC

Completed

Re-Read Study to Compare the Brain Uptake of [18F]Flutemetamol With Brain Neuritic Plaque Density Determined Postmortem

Cognitive Impairment

United States
DanceStream Projects
Alzheimer's Association

Recruiting

Stories in the Moment: Dance Program for People Living With Dementia

Dementia | Alzheimer Disease | Mild Cognitive Impairment | Lewy Body Disease | Frontotemporal Dementia | Vascular Dementia

United States
Merck Sharp & Dohme LLC

Completed

Evoked Responses as Pharmacodynamic Biomarkers in Healthy and Schizophrenic Participants (MK-4334-007)

Cognitive Impairment Associated With Schizophrenia

United States
Novartis Pharmaceuticals

Terminated

Rivastigmine in Multiple Sclerosis Patients With Cognitive Impairment (EXCITING)

Multiple Sclerosis | Cognitive Impairment

Germany
NYU Langone Health
Novartis

Completed

Rivastigmine in the Treatment of Postoperative Delirium: a Pilot Clinical Trial

Delirium | Postoperative Cognitive Dysfunction

United States
NYU Langone Health

Completed

Sleep Disordered Breathing and Alzheimer's Disease Biomarkers in Normal Aging and Mild Cognitive Impairment

Sleep Disorder

United States
Yale University

Completed

Translational Neuroscience Optimization of GlyT1 Inhibitor (NCATS)

Cognitive Impairments Associated With Schizophrenia

United States
Aptinyx
CogState Ltd.; Worldwide Clinical Trials

Active, not recruiting

NYX-458 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Parkinson's Disease or Lewy Body Dementia (Cognition, Memory, Attention, Thinking)

Parkinson Disease | Mild Cognitive Impairment | Lewy Body Disease | Mild Dementia

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Withdrawn

CPI-613 and Hydroxychloroquine for Patients With High Risk Myelodysplastic Syndrome

Myelodysplastic Syndromes | Progressive Disease

United States
Yale University
National Alliance for Research on Schizophrenia and Depression; Donaghue Medical...

Completed

D-Serine Treatment of Negative Symptoms and Cognitive Deficits in Schizophrenia

Schizophrenia | Schizoaffective Disorder

United States
Nathan Kline Institute for Psychiatric Research

Completed

Varenicline for Cognitive Deficits and Cigarette Smoking in Schizophrenia - Efficacy and Predictors

Schizophrenia | Cigarette Smoking

United States, China, Israel
Icahn School of Medicine at Mount Sinai

Terminated

Role of Absolute Cerebral Oximetry to Prevent Neurocognitive Injury in Elderly Patients Undergoing Cardiac Surgery

Postoperative Cognitive Dysfunction | Post-Operative Delirium

United States
Icahn School of Medicine at Mount Sinai

Terminated

Cognitive Protection - Dexmedetomidine and Cognitive Reserve

Postoperative Delirium | Postoperative Cognitive Dysfunction | PD | POCD

United States
Erasmus Medical Center

Completed

Resuscitation Outcomes in the Netherlands (ROUTiNE)

Quality of Life | Cognitive Impairment | Heart Arrest | Cardiac Arrest | Outcome, Fatal | Cardiac Arrest as A Complication of Care

Netherlands
National Institute on Aging (NIA)

Unknown

Predictors of Cognitive Decline in Normal Aging

Dementia | Alzheimer Disease

United States
AbbVie (prior sponsor, Abbott)

Completed

A Phase 2 Study to Evaluate ABT-126 for the Treatment of Cognitive Deficits in Schizophrenia

Schizophrenia

United States
New York Institute of Technology

Terminated

Effects of Multiple Concussions in Retired NHL Players (NHL)

Proprioceptive Disorders | Cognitive Deficits

United States
Cognito Therapeutics, Inc.

Recruiting

A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (Hope Study, CA-0011) (Hope)

Cognitive Impairment | Dementia | Alzheimer Disease | Mild Cognitive Impairment | Cognitive Decline | Alzheimer Disease, Early Onset | Alzheimer Disease, Late Onset | MCI | Dementia Alzheimers | Mild Dementia | Dementia of Alzheimer Type | Cognitive Impairment, Mild | Alzheimer Disease 1 | Dementia, Mild | Alzheimer... and other conditions

United States
Weill Medical College of Cornell University
National Center for Advancing Translational Sciences (NCATS); Brain & Behavior... and other collaborators

Completed

Can Cognitive Training Decrease Reactive Aggression?

Schizophrenia | Cognitive Deficits | Impulsivity | Emotion | Impulsive Aggression

United States
Icahn School of Medicine at Mount Sinai
Yale University; National Institute on Aging (NIA)

Completed

Trajectory of Recovery in the Elderly (TORIE)

Postoperative Delirium | Postoperative Cognitive Dysfunction | Delayed Emergence From Anesthesia

United States
AbbVie (prior sponsor, Abbott)

Completed

Safety and Efficacy Study for Cognitive Deficits in Adult Subjects With Schizophrenia

Cognitive Deficits in Schizophrenia

United States
Rutgers, The State University of New Jersey
Horizon Blue Cross Blue Shield of New Jersey

Recruiting

Computerized Cognitive Rehabilitation in MS Patients

Multiple Sclerosis | Cognitive Impairment

United States
VA Office of Research and Development
VA New York Harbor Healthcare System; VA Boston Healthcare System; Portland VA... and other collaborators

Recruiting

Methylphenidate for the Treatment of Epilepsy-related Cognitive Deficits

Epilepsy

United States
Weill Medical College of Cornell University
Oncolys BioPharma Inc

Terminated

Phase 2 Study of OBP-301 (Telomelysin™) in Combination With Pembrolizumab and SBRT in Patients With HNSCC With Inoperable, Recurrent or Progressive Disease

Head and Neck Squamous Cell Carcinoma With Inoperable Recurrent or Progressive Disease

United States
AbbVie (prior sponsor, Abbott)

Completed

Efficacy and Safety Study for Cognitive Deficits in Adult Subjects With Schizophrenia

Cognitive Deficits in Schizophrenia

United States
Icahn School of Medicine at Mount Sinai
National Institute on Aging (NIA)

Completed

Perioperative Cognitive Function - Dexmedetomidine and Cognitive Reserve

Postoperative Delirium | Postoperative Cognitive Dysfunction | PD | POCD

United States
Cephalon

Completed

Efficacy and Safety of Armodafinil as Adjunctive Therapy in Schizophrenic Adults With Cognitive Deficits

Schizophrenia

United States
The University of New South Wales

Recruiting

Healthy Body & Mind Program for Older Adults Living With Osteoarthritis and Cognitive Decline

Osteoarthritis | Cognitive Decline

Australia
Garvan Institute of Medical Research
National Health and Medical Research Council, Australia

Recruiting

Preventing Cognitive Decline With Metformin (MetMemory)

Cognitive Decline

Australia
Opexa Therapeutics, Inc.

Completed

Study of Tcelna (Imilecleucel-T) in Secondary Progressive Multiple Sclerosis (Abili-T)

Multiple Sclerosis | Autoimmune Diseases of the Nervous System | Disease Progression | Secondary Progressive Multiple Sclerosis | Brain Atrophy

United States, Canada

Clinical Trials on Cognitive Impairment, Progressive in New Zealand

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CROs in Gabon

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