Clinical Trials on Cognitively Healthy Subjects Influenced by Psychoactive Drugs

Total 56 results

K. Lieb

Completed

Cognitive Hyper-performance - Effects of Stimulating Substances in Chess-players (CHESS)

Cognitively Healthy Subjects Influenced by Psychoactive Drugs

Germany
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Drug-Drug Interaction of Pyrotinib With a Moderate CYP3A Inducer

Healthy Subjects, Drug-drug Interaction, Pyrotinib

China
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

Drug-drug Interaction Study With MDV3100 (ASP9785) and Gemfibrozil and Itraconazole

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction

France
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Effect of Multiple Doses of Gemfribozil on a Single Dose of ASP3652, and to Assess the Effects of Multiple Doses of ASP3652 on a Single Dose of Repaglinide in the Body of Healthy Subjects

Healthy Subjects | Drug-Drug Interaction (DDI)

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate Whether Verapamil Has an Effect on the Uptake and Elimination of Solifenacin and Tamsulosin When Administered in a Combination Tablet

Healthy Subjects | Drug-Drug Interaction (DDI)

France
Astellas Pharma Europe B.V.

Completed

Study to Evaluate the Effect of Solifenacin and Mirabegron on the Digoxin Concentrations in Blood in Healthy Subjects

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction (DDI)

Germany
Daiichi Sankyo Co., Ltd.

Completed

A Study of the Effect of a Moderate CYP3A Inducer Efavirenz on Quizartinib Pharmacokinetics in Healthy Participants

Healthy Subjects | Pharmacokinetics | Drug-drug Interaction | Quizartinib

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

Drug-Drug Interaction of SHR1459 With a Strong CYP3A Index Inducer (Rifampicin)

Healthy Subjects, Drug-drug Interaction, Pharmacokinetics, SHR1459

China
Daiichi Sankyo Co., Ltd.

Completed

A Study of the Effect of Quizartinib on the Pharmacokinetics of the P-gp Substrate Dabigatran Etexilate in Healthy Participants

Healthy Subjects | Pharmacokinetics | Drug-drug Interaction | Quizartinib

United States
Astellas Pharma Europe B.V.

Completed

Study to Evaluate the Effect of Solifenacin and Mirabegron on the Tamsulosin Hydrochloride (HCl) Concentrations in Blood in Healthy Male Subjects

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction (DDI)

Germany
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Evaluate How a Drug That Alters Liver Enzymes (Rifampin) Affects the Metabolism of Enzalutamide in Men

Healthy Subjects | Drug-Drug Interaction (DDI) | Pharmacokinetics of Enzalutamide

Germany
Astellas Pharma Inc

Completed

Pharmacokinetic Interaction Study to Assess the Effect of ASP015K on Mycophenolate Mofetil in Healthy Volunteers

Healthy Subjects | Drug Interactions | Pharmacokinetics of ASP015K

United States
Astellas Pharma Inc

Completed

Pharmacokinetic Interaction Study to Assess the Effect of ASP015K on Tacrolimus in Healthy Volunteers

Healthy Subjects | Drug Interactions | Pharmacokinetics of ASP015K

United States
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Interaction Between ASP1707 and Itraconazole in Healthy Female Subjects

Healthy Subjects | Pharmacokinetics | DDI (Drug-Drug Interaction)

Germany
Astellas Pharma Europe B.V.
Cubist Pharmaceuticals LLC

Completed

A Study to Assess the Effects of Multiple Doses of Fidaxomicin on a Single Dose of Rosuvastatin in Healthy Male Subjects

Healthy Subjects | Drug-Drug Interaction (DDI) | Intestinal Absorption | Pharmacokinetics of Rosuvastatin | Pharmacokinetics of Fidaxomicin

Germany
Beijing Tiantan Hospital

Active, not recruiting

PolyvasculaR Evaluation for Cognitive Impairment and vaScular Events (PRECISE)

Healthy Subjects

China
Universidad Nacional Autonoma de Mexico

Completed

Evaluation of the Bioavailability of Dexamethasone in Healthy Subjects

Inflammation | Healthy Subjects | Intravenous Drug Usage | Dexamethasone Administration | Intranasal Administration

Mexico
Fondazione Golgi Cenci
University of Pavia; Mario Negri Institute for Pharmacological Research; Alzheimer... and other collaborators

Completed

Cognitive Stimulation in Elderly Individuals at Risk to Develop Dementia (Allena-Mente). (Allena-Mente)

Mild Cognitive Impairment | Healthy Subjects With Family History for Dementia

Italy
University of California, San Francisco
National Cancer Institute (NCI)

Completed

Lay Health Worker Outreach in Increasing Colorectal Cancer Screening in Asian Americans

Colorectal Carcinoma | Healthy Subject | Health Status Unknown

United States
Université Catholique de Louvain
Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Recruiting

Telerehabilitation Through Serious Games in Virtual Reality in a Stroke Population (AutoRReVi) (AutoRReVi)

Stroke | Cognitive Impairment | Healthy Subjects | Hemiparesis

Belgium
Bright Cloud International Corp
National Cancer Institute (NCI); Rutgers, The State University of New Jersey

Completed

Telerehabilitation Cognitive Impairments Following Chemotherapy Usability Study (TCIFCU)

Healthy | Chemotherapy-Related Cognitive Impairment

United States
Roswell Park Cancer Institute
Susan G. Komen Breast Cancer Foundation

Recruiting

Photoacoustic Imaging of the Breast in Patients With Breast Cancer and Healthy Subjects

Breast Carcinoma | Healthy Subject

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Technology and Health Communication in Improving Health Outcomes in Patients Scheduled for Mammography

Healthy Subject | Female Breast Carcinoma

United States
Ostfold Hospital Trust
The Dam Foundation; Sykehuset Innlandet HF; Norwegian Health Association

Completed

Psychotropic Drug Use in the Elderly Living in Nursing Homes and the Influence of a Structured Drug Review

Depression | Quality of Life | Anxiety | Cognitive Symptom | Drug Use | Physical Health | Activity of Daily Living | Neuropsychiatric Syndrome

Norway
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Compare Capsule and Tablet Forms of MDV3100 (Enzalutamide) After Administration of a Single Set Dose Under Fasted Conditions in Healthy Male Subjects

Healthy Subjects | Relative Bioavailability | Castration Resistant Prostate Cancer (CRPC) | MDV3100

Germany
UNC Lineberger Comprehensive Cancer Center
American Cancer Society, Inc.

Completed

Chemotherapy-related Cognitive Impairment and Acute Leukemia

Acute Myeloid Leukemia

United States
NYU Langone Health

Completed

An Investigation of Chemotherapy Induced Cognitive Impairments in Breast Cancer Survivors

Breast Cancer

United States
Universidad de Granada

Enrolling by invitation

Telehealth Program to Prevent Cancer and Chemotherapy-related Cognitive Impairment.

Breast Neoplasms

Spain
Stanford University
National Cancer Institute (NCI)

Completed

Integrin Alpha-v-Beta and [18F]-R01-MG-F2 PET/CT in Measuring Response in Patients With Pancreatic Cancer and Healthy Volunteers

Pancreatic Carcinoma | Healthy Subject

United States
Sun Yat-sen University

Recruiting

GM1 Prophylaxis for Post-chemotherapy Cognitive Impairment in Patients With Early Operable Breast Cancer

Breast Cancer | Chemotherapy-Related Cognitive Impairment

China
Thomas Jefferson University
United States Department of Defense

Active, not recruiting

The Peer Genetic Study

Prostate Carcinoma | Healthy Subject

United States
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

Aerobic Dance During Chemotherapy in Breast Cancer Patients With Cognitive Impairment (ADANC)

Breast Neoplasms | Cognitive Dysfunction | Chemotherapy-Related Cognitive Impairment | Exercise Therapy | Dance Therapy

China
The University of Hong Kong
Chinese University of Hong Kong

Completed

Acupuncture Prevents Chemobrain in Breast Cancer Patients

Breast Cancer | Mild Cognitive Impairment | Drug-Related Side Effects and Adverse Reactions | Chemo-brain

China, Hong Kong
Xiaorong Dong

Unknown

The Role of Microbiota on the Development of Lung Cancer

Healthy Subjects | NSCLC Stage IV | NSCLC, Stage III | NSCLC, Stage I | NSCLC, Stage II

China
University of Miami

Completed

Individualized Piano Instruction (IPI) for Improving Cognition in Breast Cancer Survivors.

Breast Cancer | Chemotherapy-Related Cognitive Impairment

United States
Institut Bergonié
University of Bordeaux; Association Oncogite

Recruiting

Evaluation of Cognitive Management for Chemobrain in Patients Treated for Breast Cancer. (e-ONCOGITE)

Breast Cancer

France
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Terminated

Photoacoustic Imaging in Diagnosing Changes in Tumors in Participants With Breast Cancer, Sarcoma, Skin Cancer, or Soft Tissue Malignancy and Healthy Volunteers

Sarcoma | Breast Carcinoma | Skin Carcinoma | Healthy Subject | Malignant Soft Tissue Neoplasm

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Withdrawn

BBBD Followed By Methotrexate and Carboplatin With or Without Trastuzumab in Treating Women With Breast Cancer That Has Spread to the Brain

Breast Cancer | Brain and Central Nervous System Tumors | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment | Drug/Agent Toxicity by Tissue/Organ
Rachel Miller
Office of US Army Medical Research and Material Command

Completed

Chemotherapy-Induced Cognitive Impairment in Ovarian Cancer Patients

Chemotherapy-induced Cognitive Impairment

United States
Alexandria University

Completed

Effect of Acceptance and Commitment Therapy Based Interventions on Mental Health and Cognitive Impairment for Patients With Advanced Colorectal Cancer

Acceptance and Commitment Therapy, Mental Health, Cognitive Impairment,Colorectal Cancer

Egypt
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Magnetic Resonance (MR) Imaging & Blood Biomarkers for Head and Neck Cancer

Head and Neck Cancer | Cutaneous Squamous Cell Carcinoma of the Head and Neck | Healthy Subject

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

MRI and Cardio-Pulmonary Exercise Testing in Evaluating Exercise Intolerance in Patients With Stage I-III Breast Cancer After Chemotherapy Treatment

Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer | Healthy Subject

United States
Guido A. Davidzon, MD, SM

Completed

[18F]DASA-23 and PET Scan in Evaluating Pyruvate Kinase M2 Expression in Patients With Intracranial Tumors or Recurrent Glioblastoma and Healthy Volunteers

Glioblastoma | Healthy Subject | Intracranial Neoplasm

United States
Rigshospitalet, Denmark

Recruiting

Investigating Cognitive Impairment in Young Patients With Cancer Prospectively (MyBrain)

Sarcoma | Leukemia | Cancer | Hodgkin Lymphoma | Non Hodgkin Lymphoma | Childhood Cancer | Chemotherapeutic Toxicity | Chemotherapy-Related Cognitive Impairment | Chemo-brain | Testicular Cancer

Denmark
University of California, Irvine
Jarrow Formulas Inc

Not yet recruiting

Effect of NAC on Preventing Chemo-Related Cognitive Impairments in Ovarian Ca Pts Treated W/ PBT

Cognitive Impairment | Ovarian Cancer
Stanford University
National Cancer Institute (NCI)

Completed

Functional Magnetic Resonance Imaging in Assessing Affect Reactivity and Regulation in Patients With Stage 0-III Breast Cancer

Stage 0 Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer | Healthy Subject

United States
Tanta University

Enrolling by invitation

Role of Silymarin in Chemotherapy Toxicity and Cognition Improvement in Breast Cancer Patients

Breast Cancer | Cognitive Impairment | Peripheral Neuropathy | Cardiac Toxicities | Hepatic Toxicity

Egypt
University of Southern California
National Cancer Institute (NCI)

Active, not recruiting

Myeloid Derived Suppressor Cells Clinical Assay in Finding Kidney Cancer

Metastatic Renal Cell Cancer | Recurrent Renal Cell Carcinoma | Stage III Renal Cell Cancer | Healthy Subject | Stage I Renal Cell Cancer | Stage II Renal Cell Cancer

United States
IRCCS San Camillo, Venezia, Italy

Active, not recruiting

Neural and Cognitive Correlates of Pragmatic Abilities (APACS_Neuro)

Healthy | Traumatic Brain Injury | Mild Cognitive Impairment | Right Hemispheric Stroke | Left Hemispheric Stroke | Right Hemispheric Brain Tumor | Left Hemispheric Brain Tumor

Italy
Amsterdam University Medical Center

Enrolling by invitation

Cognitive Functioning and Health Related Quality of Life in Retinoblastoma Survivors (RbNeuroQoL)

Retinoblastoma | Neurocognitive Dysfunction | Health-Related Behavior

Netherlands

Clinical Trials on Cognitively Healthy Subjects Influenced by Psychoactive Drugs

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